Enables several functions, including histone deacetylase binding activity; nuclear receptor binding activity; and peroxisome proliferator activated receptor binding activity. Involved in several processes, including lactation; negative regulation of macromolecule biosynthetic process; and skeletal muscle tissue development. Located in perinuclear region of cytoplasm. Used to study anxiety disorder and polycystic ovary syndrome. Biomarker of hypothyroidism and polycystic ovary syndrome. Orthologous to human NCOR1 (nuclear receptor corepressor 1); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; cortisol signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
[bisphenol A co-treated with Estradiol] results in increased expression of NCOR1 mRNA and [Estradiol co-treated with ormeloxifene] promotes the reaction [NCOR1 protein binds to ESR1 protein]
tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]] and tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]] more ...
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NCOR1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NCOR1 mRNA and bis(4-hydroxyphenyl)sulfone inhibits the reaction [ESR1 protein binds to NCOR1 protein]
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of NCOR1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of NCOR1 mRNA
Glucose promotes the reaction [NCOR1 protein binds to SRI promoter] and NCOR1 protein affects the reaction [Glucose results in decreased expression of SRI protein]
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of NCOR1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of NCOR1 mRNA
[bisphenol A binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to NCOR1 protein modified form] more ...
[bisphenol A co-treated with Estradiol] results in increased expression of NCOR1 mRNA and [bisphenol A co-treated with tributyltin] results in increased expression of NCOR1 mRNA
7-hydroxytheonellasterol inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [NCOR1 protein binds to SLC51A promoter]] and Chenodeoxycholic Acid inhibits the reaction [NCOR1 protein binds to SLC51A promoter]
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of NCOR1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NCOR1 gene
[Cyproterone Acetate binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to NCOR1 protein modified form] and [Cyproterone Acetate binds to AR protein] promotes the reaction [NCOR1 protein binds to KLK3 promoter]
Glucose promotes the reaction [NCOR1 protein binds to SRI promoter] and NCOR1 protein affects the reaction [Glucose results in decreased expression of SRI protein]
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NCOR1 mRNA
Glucose promotes the reaction [NCOR1 protein binds to SRI promoter] and NCOR1 protein affects the reaction [Glucose results in decreased expression of SRI protein]
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of NCOR1 mRNA
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of NCOR1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NCOR1 gene
[Estradiol co-treated with ormeloxifene] promotes the reaction [NCOR1 protein binds to ESR1 protein] and ormeloxifene promotes the reaction [NCOR1 protein binds to ESR1 protein]
[Phosphorus co-treated with paricalcitol] affects the localization of NCOR1 protein and [Phosphorus co-treated with paricalcitol] results in decreased expression of NCOR1 protein
[Phosphorus co-treated with paricalcitol] affects the localization of NCOR1 protein and [Phosphorus co-treated with paricalcitol] results in decreased expression of NCOR1 protein
[Phosphorus co-treated with paricalcitol] affects the localization of NCOR1 protein and [Phosphorus co-treated with paricalcitol] results in decreased expression of NCOR1 protein
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NCOR1 mRNA and pirinixic acid inhibits the reaction [PPARA protein binds to NCOR1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]] more ...
Effects of neonatal exposure to bisphenol A on steroid regulation of vascular endothelial growth factor expression and endothelial cell proliferation in the adult rat uterus.
Expression of estrogen receptor co-regulators SRC-1, RIP140 and NCoR and their interaction with estrogen receptor in rat uterus, under the influence of ormeloxifene.
Nuclear receptor co-repressor is required to maintain proliferation of normal intestinal epithelial cells in culture and down-modulates the expression of pigment epithelium-derived factor.
Expression of nuclear hormone receptors, their coregulators and type I iodothyronine 5'-deiodinase gene in mammary tissue of nonlactating and postlactating rats.
A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.
Quantification of thyroid hormone receptor isoforms, 9-cis retinoic acid receptor gamma, and nuclear receptor co-repressor by reverse-transcriptase PCR in maturing and adult skeletal muscles of rat.
Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain.
