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Gene: Irgm (immunity-related GTPase M) Rattus norvegicus
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Symbol: Irgm
Name: immunity-related GTPase M
Description: Predicted to have several functions, including GTPase activity; protein domain specific binding activity; and protein serine/threonine kinase activator activity. Predicted to be involved in several processes, including positive regulation of cellular metabolic process; positive regulation of innate immune response; and response to bacterium. Predicted to localize to several cellular components, including the Golgi membrane; autolysosome; and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in inflammatory bowel disease 19 and tuberculosis. Orthologous to human IRGM (immunity related GTPase M); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ifggd3; Ifi1; immunity-related GTPase family M protein; immunity-related GTPase family, M; interferon inducible protein 1; interferon-gamma-inducible GTPase Ifggd3 protein; LOC303090
Orthologs:
Homo sapiens (human) : IRGM (immunity related GTPase M)  HGNC  Alliance
Mus musculus (house mouse) : Irgm1 (immunity-related GTPase family M member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irgm (immunity related GTPase M)
Pan paniscus (bonobo/pygmy chimpanzee) : IRGM (immunity related GTPase M)
Canis lupus familiaris (dog) : LOC606863 (immunity-related GTPase family M protein-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irgm (immunity related GTPase M)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01034,213,885 - 34,221,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1034,213,936 - 34,221,928 (-)Ensembl
Rnor_5.01033,997,565 - 34,005,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41034,132,512 - 34,140,450 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11034,133,560 - 34,141,499 (-)NCBI
Celera1032,619,552 - 32,627,490 (-)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Irgm
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305163
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.