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Gene: Cryba1 (crystallin, beta A1) Rattus norvegicus
Symbol: Cryba1
Name: crystallin, beta A1
RGD ID: 2415
Description: Predicted to have identical protein binding activity. Involved in several processes, including lens development in camera-type eye; negative regulation of intracellular signal transduction; and positive regulation of anoikis. Localizes to cytoplasm and nucleus. Used to study retinal detachment. Biomarker of ocular hypertension. Human ortholog(s) of this gene implicated in cataract and cataract 10 multiple types. Orthologous to human CRYBA1 (crystallin beta A1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BA3A1C; beta-A3; beta-A3 crystallin; beta-crystallin A3
Homo sapiens (human) : CRYBA1 (crystallin beta A1)  HGNC  Alliance
Mus musculus (house mouse) : Cryba1 (crystallin, beta A1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cryba1 (crystallin beta A1)
Pan paniscus (bonobo/pygmy chimpanzee) : CRYBA1 (crystallin beta A1)
Canis lupus familiaris (dog) : CRYBA1 (crystallin beta A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cryba1 (crystallin beta A1)
Sus scrofa (pig) : CRYBA1 (crystallin beta A1)
Chlorocebus sabaeus (African green monkey) : CRYBA1 (crystallin beta A1)
Heterocephalus glaber (naked mole-rat) : Cryba1 (crystallin beta A1)
more info ...
Allele / Splice: Cryba1Hiser  
Genetic Models: HHSE/Hat
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01065,160,777 - 65,167,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,161,152 - 65,167,494 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,458,061 - 66,480,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,758,929 - 63,765,451 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11063,772,566 - 63,776,395 (-)NCBI
Celera1061,589,011 - 61,595,363 (-)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cryba1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2415
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.