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Strain Registration

Strain: HHSE/Hat

Symbol: HHSE/Hat
Strain: HHSE
Substrain: Hat
RGD ID: 38676463
Citation ID: RRID:RGD_38676463
Ontology ID: RS:0004945
Alleles: Cryba1Hiser
Also Known As: NBRP Rat No: 0904; HISER-HHR/Hat
Type: mutant
Available Source: National BioResource Project for the Rat in Japan ;Depart of Biochemistry and Genome Biology, Hirosaki Univer-sity School of Medicine
Origination: National BioResource Project for the Rat in Japan ;Depart of Biochemistry and Genome Biology, Hirosaki Univer-sity School of Medicine
Description: HHSE/Hat was derived from Hirosaki hairless rat (HHR) and Hirosaki small-eye rat (HiSER), which are Sprague-Dawley rat (SDR)mutant lines. HHR was established in 1984 as a spontaneous mutant of SDR that has been inbred in Department of Biochemistry and Genome Biology Hirosaki University Graduate School of Medicine. Whole body shows hypotrichosis, abnormal differentiation of thymus, and regressed mammary gland in females. These mutations are autosomal recessive and are suggested to be due to deletion of the keratin gene cluster and the lectin-like receptor gene Ly49s3. HiSER was established in 2013 as a spontaneous mutant of Sprague-Dawley rat maintained in our course in the same way as HHR/Hat. This mutant strain has retinal detachment and the disease is progressively exacerbated. The muation is autosomal recessive and is suggested to be due to deletion of the crystallin gene Cryba1. The mutations in HHR and HiSER are on different chromosomes and do not affect each other. The mutations in HHR and HiSER are on different chromosomes and do not affect each other.
Genetic Status: Homozygous
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-09-18)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21062,608,373 - 62,614,726RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01065,160,777 - 65,167,504RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01066,458,061 - 66,480,390RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41063,758,929 - 63,765,451RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP

Region


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