Cryba1<sup>Hiser</sup> (crystallin, beta A1; HiSER mutant) - Rat Genome Database

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Gene: Cryba1Hiser (crystallin, beta A1; HiSER mutant) Rattus norvegicus
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Symbol: Cryba1Hiser
Name: crystallin, beta A1; HiSER mutant
RGD ID: 38676462
Description: HiSER was established in 2013 as a spontaneous mutant of Sprague-Dawley rat. This mutant strain has retinal detachment and the disease is progressively exacerbated. The muation is autosomal recessive and is suggested to be due to deletion of the crystallin gene Cryba1.
ASSOCIATED WITH abnormal ciliary body morphology; abnormal lens morphology; abnormal retina ganglion layer morphology
Type: allele  of Cryba1  
Previously known as: Cryba1^[Hiser]
Is Marker For: Strains:   HHSE/Hat  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene. Yamada T, etal., Biochem J. 2015 Oct 15;471(2):293-305. doi: 10.1042/BJ20150165. Epub 2015 Aug 24.

Genomics


Related Rat Strains
The following Strains have been annotated to Cryba1Hiser
HHSE/Hat    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information