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Gene: Acadvl (acyl-CoA dehydrogenase, very long chain) Rattus norvegicus
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Symbol: Acadvl
Name: acyl-CoA dehydrogenase, very long chain
Description: Exhibits fatty-acyl-CoA binding activity; flavin adenine dinucleotide binding activity; and very-long-chain-acyl-CoA dehydrogenase activity. Involved in fatty acid beta-oxidation. Localizes to the mitochondrial inner membrane. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in very long chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADVL (acyl-CoA dehydrogenase very long chain); PARTICIPATES IN fatty acid beta degradation pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acyl-Coa dehydrogenase Very long chain; acyl-Coenzyme A dehydrogenase, very long chain; MGC93660; Very long chain Acyl-Coa dehydrogenase; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VLCAD; VLCAD very-long-chain acyl-CoA dehydrogenase; VLCAD, very-long-chain acyl-CoA dehydrogenase
Orthologs:
Homo sapiens (human) : ACADVL (acyl-CoA dehydrogenase very long chain)  HGNC  Alliance
Mus musculus (house mouse) : Acadvl (acyl-Coenzyme A dehydrogenase, very long chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acadvl (acyl-CoA dehydrogenase very long chain)
Pan paniscus (bonobo/pygmy chimpanzee) : ACADVL (acyl-CoA dehydrogenase very long chain)
Canis lupus familiaris (dog) : ACADVL (acyl-CoA dehydrogenase very long chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acadvl (acyl-CoA dehydrogenase very long chain)
Sus scrofa (pig) : ACADVL (acyl-CoA dehydrogenase very long chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01056,619,321 - 56,624,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,619,303 - 56,624,526 (-)Ensembl
Rnor_5.01056,364,440 - 56,369,587 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,856,233 - 56,861,380 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,869,857 - 56,875,003 (-)NCBI
Celera1053,886,459 - 53,891,606 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acadvl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2014
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.