Mat2b (methionine adenosyltransferase 2 non-catalytic beta subunit) - Rat Genome Database

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Gene: Mat2b (methionine adenosyltransferase 2 non-catalytic beta subunit) Rattus norvegicus
Analyze
Symbol: Mat2b
Name: methionine adenosyltransferase 2 non-catalytic beta subunit (Ensembl:methionine adenosyltransferase 2B)
RGD ID: 1593534
Description: Predicted to enable enzyme binding activity and methionine adenosyltransferase regulator activity. Predicted to be involved in S-adenosylmethionine biosynthetic process. Predicted to be located in nucleus. Predicted to be part of methionine adenosyltransferase complex. Orthologous to human MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit); PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; furan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC689330; MAT II beta; methionine adenosyltransferase 2 beta subunit; methionine adenosyltransferase 2 subunit beta; methionine adenosyltransferase 2B; methionine adenosyltransferase II, beta; MGC94725; similar to methionine adenosyltransferase II, beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,609,202 - 25,626,694 (-)NCBIGRCr8
mRatBN7.21025,106,928 - 25,122,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,106,930 - 25,122,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,861,993 - 29,877,026 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,350,532 - 29,365,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,837,185 - 24,852,218 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,832,096 - 25,848,045 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,686,294 - 25,701,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,713,132 - 25,718,879 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1024,666,794 - 24,680,351 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
methionine adenosyltransferase complex  (IBA,IEA,ISO,ISS)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. S-adenosylmethionine in liver health, injury, and cancer. Lu SC and Mato JM, Physiol Rev. 2012 Oct;92(4):1515-42. doi: 10.1152/physrev.00047.2011.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10644686   PMID:12477932   PMID:18614015   PMID:21630459   PMID:23533145   PMID:25075345   PMID:31686458   PMID:31904090   PMID:35287147  


Genomics

Comparative Map Data
Mat2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,609,202 - 25,626,694 (-)NCBIGRCr8
mRatBN7.21025,106,928 - 25,122,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,106,930 - 25,122,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,861,993 - 29,877,026 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,350,532 - 29,365,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,837,185 - 24,852,218 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,832,096 - 25,848,045 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,686,294 - 25,701,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,713,132 - 25,718,879 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1024,666,794 - 24,680,351 (-)NCBICelera
Cytogenetic Map10q12NCBI
MAT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,503,064 - 163,519,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,503,114 - 163,519,558 (+)EnsemblGRCh38hg38GRCh38
GRCh375162,930,070 - 162,946,360 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,862,809 - 162,878,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera5158,964,332 - 158,980,423 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5158,029,749 - 158,046,037 (+)NCBIHuRef
CHM1_15162,362,532 - 162,378,812 (+)NCBICHM1_1
T2T-CHM13v2.05164,038,230 - 164,054,512 (+)NCBIT2T-CHM13v2.0
Mat2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,570,141 - 40,586,030 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)EnsemblGRCm39 Ensembl
GRCm381140,679,314 - 40,695,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,492,816 - 40,506,115 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361140,522,737 - 40,536,036 (-)NCBIMGSCv36mm8
Celera1144,529,462 - 44,542,765 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.4NCBI
Mat2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBIChiLan1.0ChiLan1.0
MAT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24158,675,643 - 158,692,011 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15156,815,297 - 156,831,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05158,879,425 - 158,895,690 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15165,656,086 - 165,672,176 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,656,086 - 165,672,176 (+)Ensemblpanpan1.1panPan2
MAT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,703,991 - 47,726,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,597,100 - 47,621,728 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0448,134,581 - 48,159,235 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl448,137,166 - 48,156,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1447,918,036 - 47,942,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0448,076,525 - 48,101,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0448,596,150 - 48,620,797 (-)NCBIUU_Cfam_GSD_1.0
Mat2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,094,901 - 102,111,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936515544,037 - 561,182 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936515544,218 - 561,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,255,358 - 60,274,135 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11660,255,541 - 60,274,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,065,436 - 65,111,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244929
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,776,808 - 65,792,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2365,779,437 - 65,792,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666097990,267 - 1,006,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mat2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473326,297,653 - 26,306,942 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473326,296,920 - 26,309,228 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mat2b
130 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:84
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000004269
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum immunoglobulin E level (CMO:0002101)102291826836400810Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat

Markers in Region
AU022853  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,106,950 - 25,107,155 (+)MAPPERmRatBN7.2
Rnor_6.01025,832,119 - 25,832,323NCBIRnor6.0
Rnor_5.01025,686,319 - 25,686,523UniSTSRnor5.0
RGSC_v3.41025,713,155 - 25,713,359UniSTSRGSC3.4
Celera1024,666,817 - 24,667,021UniSTS
AI182287  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,107,071 - 25,107,233 (+)MAPPERmRatBN7.2
Rnor_6.01025,832,240 - 25,832,401NCBIRnor6.0
Rnor_5.01025,686,440 - 25,686,601UniSTSRnor5.0
RGSC_v3.41025,713,276 - 25,713,437UniSTSRGSC3.4
Celera1024,666,938 - 24,667,099UniSTS
RH134368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,107,066 - 25,107,263 (+)MAPPERmRatBN7.2
Rnor_6.01025,832,235 - 25,832,431NCBIRnor6.0
Rnor_5.01025,686,435 - 25,686,631UniSTSRnor5.0
RGSC_v3.41025,713,271 - 25,713,467UniSTSRGSC3.4
Celera1024,666,933 - 24,667,129UniSTS
RH 3.4 Map10254.53UniSTS
RH143265  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,107,389 - 25,107,514 (+)MAPPERmRatBN7.2
Rnor_6.01025,832,558 - 25,832,682NCBIRnor6.0
Rnor_5.01025,686,758 - 25,686,882UniSTSRnor5.0
RGSC_v3.41025,713,594 - 25,713,718UniSTSRGSC3.4
Celera1024,667,256 - 24,667,380UniSTS
RH 3.4 Map10256.83UniSTS
RH137200  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,121,310 - 25,121,520 (+)MAPPERmRatBN7.2
Rnor_6.01025,846,450 - 25,846,659NCBIRnor6.0
Rnor_5.01025,700,229 - 25,700,438UniSTSRnor5.0
Celera1024,681,167 - 24,681,376UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000004269   ⟹   ENSRNOP00000004269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1025,106,930 - 25,120,544 (-)Ensembl
Rnor_6.0 Ensembl1025,832,098 - 25,845,634 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082076   ⟹   ENSRNOP00000068549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1025,106,930 - 25,117,823 (-)Ensembl
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118093   ⟹   ENSRNOP00000084010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1025,107,158 - 25,122,777 (-)Ensembl
RefSeq Acc Id: NM_001044282   ⟹   NP_001037747
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81025,609,202 - 25,622,769 (-)NCBI
mRatBN7.21025,106,928 - 25,120,495 (-)NCBI
Rnor_6.01025,832,096 - 25,845,634 (-)NCBI
Rnor_5.01025,686,294 - 25,701,795 (-)NCBI
RGSC_v3.41025,713,132 - 25,718,879 (-)ENTREZGENE
Celera1024,666,794 - 24,680,351 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006246126   ⟹   XP_006246188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81025,609,202 - 25,626,694 (-)NCBI
mRatBN7.21025,107,041 - 25,122,982 (-)NCBI
Rnor_6.01025,832,719 - 25,848,045 (-)NCBI
Rnor_5.01025,686,294 - 25,701,795 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001037747 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246188 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85899 (Get FASTA)   NCBI Sequence Viewer  
  EDM04110 (Get FASTA)   NCBI Sequence Viewer  
  EDM04111 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004269.6
  ENSRNOP00000068549.2
  ENSRNOP00000084010.1
GenBank Protein Q5U2R0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001037747   ⟸   NM_001044282
- UniProtKB: Q5U2R0 (UniProtKB/Swiss-Prot),   A0A8L2Q226 (UniProtKB/TrEMBL),   A6HDK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246188   ⟸   XM_006246126
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT30 (UniProtKB/TrEMBL),   A0A8I5ZYI5 (UniProtKB/TrEMBL),   A6HDK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004269   ⟸   ENSRNOT00000004269
RefSeq Acc Id: ENSRNOP00000068549   ⟸   ENSRNOT00000082076
RefSeq Acc Id: ENSRNOP00000084010   ⟸   ENSRNOT00000118093
Protein Domains
RmlD-like substrate binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2R0-F1-model_v2 AlphaFold Q5U2R0 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697105
Promoter ID:EPDNEW_R7630
Type:initiation region
Name:Mat2b_1
Description:methionine adenosyltransferase 2B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01025,845,672 - 25,845,732EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593534 AgrOrtholog
BioCyc Gene G2FUF-25493 BioCyc
BioCyc Pathway METHIONINE-DEG1-PWY [L-methionine degradation I (to L-homocysteine)] BioCyc
  PWY-5041 [S-adenosyl-L-methionine salvage II] BioCyc
BioCyc Pathway Image METHIONINE-DEG1-PWY BioCyc
  PWY-5041 BioCyc
Ensembl Genes ENSRNOG00000003177 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004269.7 UniProtKB/TrEMBL
  ENSRNOT00000082076.2 UniProtKB/TrEMBL
  ENSRNOT00000118093.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7193416 IMAGE-MGC_LOAD
InterPro dTDP_dehydrorham_reduct UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RmlD-like-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:683630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94725 IMAGE-MGC_LOAD
NCBI Gene Mat2b ENTREZGENE
PANTHER METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10491 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RmlD_sub_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mat2b PhenoGen
RatGTEx ENSRNOG00000003177 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JT30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q226 ENTREZGENE, UniProtKB/TrEMBL
  A6HDK4 ENTREZGENE, UniProtKB/TrEMBL
  A6HDK5 ENTREZGENE, UniProtKB/TrEMBL
  MAT2B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-18 Mat2b  methionine adenosyltransferase 2 non-catalytic beta subunit  Mat2b  methionine adenosyltransferase 2B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-10 Mat2b  methionine adenosyltransferase 2B  Mat2b  methionine adenosyltransferase II, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-09-08 Mat2b  methionine adenosyltransferase II, beta  MGC94725  similar to methionine adenosyltransferase II, beta  Data merged from RGD:1584521 737654 APPROVED
2008-03-06 Mat2b  methionine adenosyltransferase II, beta  LOC689330  similar to methionine adenosyltransferase II, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689330  similar to methionine adenosyltransferase II, beta      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 MGC94725  similar to methionine adenosyltransferase II, beta      Symbol and Name status set to provisional 70820 PROVISIONAL