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Gene: Prop1 (PROP paired-like homeobox 1) Rattus norvegicus
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Symbol: Prop1
Name: PROP paired-like homeobox 1
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II distal enhancer sequence-specific DNA binding activity; and beta-catenin binding activity. Predicted to be involved in several processes, including canonical Wnt signaling pathway; diencephalon development; and regulation of transcription by RNA polymerase II. Predicted to localize to the transcription factor complex. Human ortholog(s) of this gene implicated in hypogonadism; hypopituitarism; and panhypopituitarism. Orthologous to human PROP1 (PROP paired-like homeobox 1); INTERACTS WITH ammonium chloride; bisphenol A; 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein prophet of Pit-1; paired like homeodomain factor 1; prophet of Pit1 paired-like homeodomain transcription factor; prophet of Pit1, paired-like homeodomain transcription factor
Orthologs:
Homo sapiens (human) : PROP1 (PROP paired-like homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Prop1 (paired like homeodomain factor 1)  MGI  Alliance
Canis lupus familiaris (dog) : PROP1 (PROP paired-like homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prop1 (PROP paired-like homeobox 1)
Sus scrofa (pig) : PROP1 (PROP paired-like homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01036,449,920 - 36,452,381 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1036,449,920 - 36,452,378 (-)Ensembl
Rnor_5.01036,222,697 - 36,225,156 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41036,527,112 - 36,529,573 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11036,528,162 - 36,530,622 (-)NCBI
Celera1034,630,514 - 34,632,778 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prop1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628759
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.