Prop1 (PROP paired-like homeobox 1) - Rat Genome Database

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Gene: Prop1 (PROP paired-like homeobox 1) Ictidomys tridecemlineatus
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Symbol: Prop1
Name: PROP paired-like homeobox 1
RGD ID: 12456104
Description: ENCODES a protein that exhibits beta-catenin binding (inferred); chromatin binding (inferred); DNA binding (inferred); INVOLVED IN adenohypophysis development (ortholog); animal organ morphogenesis (ortholog); apoptotic process (ortholog); ASSOCIATED WITH amenorrhea (ortholog); Combined Pituitary Hormone Deficiency 2 (ortholog); disorder of sexual development (ortholog); FOUND IN nucleus (inferred); transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein prophet of Pit-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213120,644,095 - 120,647,296 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,854,072 - 1,856,657 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,854,072 - 1,856,657 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Prop1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213120,644,095 - 120,647,296 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,854,072 - 1,856,657 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,854,072 - 1,856,657 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PROP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385177,992,235 - 177,996,242 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5177,992,235 - 177,996,242 (-)EnsemblGRCh38hg38GRCh38
GRCh375177,419,236 - 177,423,243 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365177,351,842 - 177,355,849 (-)NCBINCBI36Build 36hg18NCBI36
Build 345177,351,841 - 177,355,849NCBI
Cytogenetic Map5q35.3NCBI
HuRef5172,154,313 - 172,158,320 (-)NCBIHuRef
CHM1_15176,851,155 - 176,855,162 (-)NCBICHM1_1
T2T-CHM13v2.05178,543,102 - 178,547,110 (-)NCBIT2T-CHM13v2.0
Prop1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,841,633 - 50,844,584 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,841,633 - 50,844,592 (-)EnsemblGRCm39 Ensembl
GRCm381150,950,806 - 50,953,757 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,950,806 - 50,953,765 (-)EnsemblGRCm38mm10GRCm38
MGSCv371150,764,308 - 50,767,134 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,794,229 - 50,797,055 (-)NCBIMGSCv36mm8
MGSCv361151,370,609 - 51,374,220 (-)NCBIMGSCv36mm8
Cytogenetic Map11B1.3NCBI
cM Map1130.95NCBI
Prop1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,772,968 - 35,775,443 (-)NCBIGRCr8
mRatBN7.21035,271,959 - 35,274,434 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1035,271,973 - 35,274,434 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,966,675 - 39,969,150 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01039,456,986 - 39,459,461 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,960,358 - 34,962,833 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01036,449,920 - 36,452,381 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1036,449,920 - 36,452,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,222,697 - 36,225,156 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41036,527,112 - 36,529,573 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11036,528,162 - 36,530,622 (-)NCBI
Celera1034,630,514 - 34,632,778 (-)NCBICelera
Cytogenetic Map10q22NCBI
PROP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24172,868,712 - 172,875,052 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15171,008,253 - 171,014,594 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05173,086,726 - 173,090,461 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PROP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1112,739,958 - 2,742,576 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl112,739,958 - 2,743,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,883,875 - 2,886,493 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0112,716,274 - 2,718,892 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl112,715,535 - 2,719,844 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1112,687,403 - 2,690,021 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0112,765,895 - 2,768,512 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,006,789 - 3,009,407 (+)NCBIUU_Cfam_GSD_1.0
PROP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl279,627,603 - 79,631,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1279,627,466 - 79,631,270 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2281,214,581 - 81,218,380 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PROP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12379,704,746 - 79,710,013 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2379,705,287 - 79,708,566 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607510,948,977 - 10,953,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prop1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473341,850,474 - 41,856,459 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473341,852,638 - 41,856,493 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005339353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010002273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000013568   ⟹   ENSSTOP00000012157
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367391,854,072 - 1,856,657 (-)Ensembl
RefSeq Acc Id: XM_005339353   ⟹   XP_005339410
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,644,095 - 120,647,296 (-)NCBI
SpeTri2.0NW_0049367391,854,072 - 1,856,657 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005339410 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012157.3
GenBank Protein KAG3265705 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005339410   ⟸   XM_005339353
- UniProtKB: I3ML91 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000012157   ⟸   ENSSTOT00000013568
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013571 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013568.3 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  PROP1 UniProtKB/TrEMBL
NCBI Gene Prop1 ENTREZGENE
PANTHER HOMEOBOX PROTEIN PROPHET OF PIT-1 UniProtKB/TrEMBL
  PTHR47409 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt I3ML91 ENTREZGENE, UniProtKB/TrEMBL