Exhibits D-glucose transmembrane transporter activity. Involved in several processes, including glucose import; regulation of synaptic vesicle budding from presynaptic endocytic zone membrane; and response to ethanol. Localizes to several cellular components, including the T-tubule; clathrin-coated pit; and cytoplasm. Colocalizes with the vesicle. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; facilitative sugar transporter mediated glucose transport pathway; insulin signaling pathway; INTERACTS WITH (R)-carnitine; (R,R)-tramadol; (S)-naringenin.
naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA], naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose], Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]
2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]] more ...
Melatonin inhibits the reaction [Triiodothyronine, Reverse results in decreased expression of SLC2A4 mRNA], Vitamin E affects the reaction [Triiodothyronine, Reverse results in decreased expression of SLC2A4 mRNA]
Melatonin inhibits the reaction [Triiodothyronine, Reverse results in decreased expression of SLC2A4 mRNA], Vitamin E affects the reaction [Triiodothyronine, Reverse results in decreased expression of SLC2A4 mRNA]
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 mRNA, [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 protein
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 mRNA more ...
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA], 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA], 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose], Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]
imisopasem manganese inhibits the reaction [Alloxan results in decreased expression of SLC2A4 protein], Taurine inhibits the reaction [Alloxan affects the localization of SLC2A4 protein]
[arsenite affects the localization of SLC2A4 protein] which results in increased uptake of Deoxyglucose, arsenite inhibits the reaction [INS1 protein affects the localization of SLC2A4 protein]
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose], Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]
boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of SLC2A4 mRNA], boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of SLC2A4 protein]
Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]
[Niacin co-treated with Chromium] promotes the reaction [SLC2A4 protein binds to CAV3 protein], [Niacin co-treated with Chromium] results in increased localization of SLC2A4 protein
[Niacin co-treated with Chromium] promotes the reaction [SLC2A4 protein binds to CAV3 protein], [Niacin co-treated with Chromium] results in increased localization of SLC2A4 protein
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose], Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]
Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SLC2A4 mRNA]
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 mRNA more ...
dorsomorphin inhibits the reaction [Quercetin inhibits the reaction [INS1 protein affects the localization of SLC2A4 protein]], dorsomorphin promotes the reaction [Palmitates results in decreased expression of SLC2A4 mRNA]
gingerol inhibits the reaction [sodium arsenite results in decreased expression of SLC2A4 mRNA], gingerol inhibits the reaction [sodium arsenite results in decreased expression of SLC2A4 protein]
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [SLC2A4 gene mutant form results in increased abundance of Glutathione Disulfide]
Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA], Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]], Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with Rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 mRNA, [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with Rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]] more ...
mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA], mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
Metformin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of SLC2A4 protein], Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]
methyl pyruvate inhibits the reaction [Palmitates results in decreased expression of SLC2A4 mRNA], methyl pyruvate inhibits the reaction [Palmitates results in decreased expression of SLC2A4 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC2A4 mRNA]
[Niacin co-treated with Chromium] promotes the reaction [SLC2A4 protein binds to CAV3 protein], [Niacin co-treated with Chromium] results in increased localization of SLC2A4 protein
Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in decreased phosphorylation of SLC2A4 protein]] more ...
plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA], plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
[Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of SLC2A4 mRNA, Quercetin inhibits the reaction [Palmitic Acid results in decreased expression of SLC2A4 protein]
tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA], tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
[Testosterone co-treated with Calcitriol] results in increased expression of SLC2A4 mRNA, Metformin affects the reaction [Testosterone results in decreased expression of SLC2A4]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate affects the localization of SLC2A4 protein], Vitamin E affects the reaction [Triiodothyronine, Reverse results in decreased expression of SLC2A4 mRNA]
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Gene-Chemical Interaction Annotations
