Gfpt2 (glutamine-fructose-6-phosphate transaminase 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Gfpt2 (glutamine-fructose-6-phosphate transaminase 2) Rattus norvegicus
Analyze
Symbol: Gfpt2
Name: glutamine-fructose-6-phosphate transaminase 2
RGD ID: 1303097
Description: Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and protein N-linked glycosylation. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GFPT2 (glutamine-fructose-6-phosphate transaminase 2); PARTICIPATES IN alanine, aspartate and glutamate metabolic pathway; amino sugar metabolic pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: D-fructose-6-phosphate amidotransferase 2; GFAT 2; GFAT2; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2; glutamine:fructose 6 phosphate amidotransferase 2; glutamine:fructose-6-phosphate amidotransferase 2; hexosephosphate aminotransferase 2; MGC112555
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21034,115,005 - 34,161,329 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,115,052 - 34,161,329 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1038,790,597 - 38,836,668 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,329,012 - 7,375,083 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01033,784,262 - 33,830,334 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,279,237 - 35,325,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,279,236 - 35,325,508 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,051,132 - 35,097,280 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,290,139 - 35,336,286 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11035,291,187 - 35,337,335 (+)NCBI
Celera1033,471,073 - 33,517,016 (+)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ampicillin  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methylparaben  (ISO)
metronidazole  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
neomycin  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. A genomic analysis of rat proteases and protease inhibitors. Puente XS and Lopez-Otin C, Genome Res 2004 Apr;14(4):609-22.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Common variants in glutamine:fructose-6-phosphate amidotransferase 2 (GFPT2) gene are associated with type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels. Zhang H, etal., J Clin Endocrinol Metab. 2004 Feb;89(2):748-55.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:20439489   PMID:34735873  


Genomics

Comparative Map Data
Gfpt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21034,115,005 - 34,161,329 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,115,052 - 34,161,329 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1038,790,597 - 38,836,668 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,329,012 - 7,375,083 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01033,784,262 - 33,830,334 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,279,237 - 35,325,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,279,236 - 35,325,508 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,051,132 - 35,097,280 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,290,139 - 35,336,286 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11035,291,187 - 35,337,335 (+)NCBI
Celera1033,471,073 - 33,517,016 (+)NCBICelera
Cytogenetic Map10q21NCBI
GFPT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385180,300,698 - 180,353,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5180,300,698 - 180,353,336 (-)EnsemblGRCh38hg38GRCh38
GRCh375179,727,698 - 179,780,336 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,660,306 - 179,712,921 (-)NCBINCBI36Build 36hg18NCBI36
Build 345179,660,305 - 179,712,921NCBI
Celera5175,353,585 - 175,406,149 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5174,452,687 - 174,505,224 (-)NCBIHuRef
CHM1_15179,160,010 - 179,212,604 (-)NCBICHM1_1
T2T-CHM13v2.05180,856,156 - 180,908,788 (-)NCBIT2T-CHM13v2.0
Gfpt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391149,684,981 - 49,729,448 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1149,685,005 - 49,729,440 (+)EnsemblGRCm39 Ensembl
GRCm381149,794,155 - 49,838,620 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1149,794,178 - 49,838,613 (+)EnsemblGRCm38mm10GRCm38
MGSCv371149,607,657 - 49,652,122 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361149,637,612 - 49,682,036 (+)NCBIMGSCv36mm8
Celera1154,356,266 - 54,400,730 (+)NCBICelera
Cytogenetic Map11B1.2NCBI
cM Map1129.9NCBI
Gfpt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955408330,112 - 372,413 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955408330,112 - 372,413 (+)NCBIChiLan1.0ChiLan1.0
GFPT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan15173,487,562 - 173,542,333 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05175,504,272 - 175,558,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,815,725 - 182,869,823 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,815,719 - 182,869,823 (-)Ensemblpanpan1.1panPan2
GFPT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,378,275 - 1,419,643 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,378,336 - 1,419,653 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha111,440,563 - 1,481,926 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0111,349,822 - 1,391,200 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl111,349,855 - 1,391,191 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1111,302,674 - 1,344,040 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0111,400,733 - 1,442,090 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0111,640,780 - 1,682,142 (+)NCBIUU_Cfam_GSD_1.0
Gfpt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213119,283,259 - 119,333,923 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936739493,060 - 543,702 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936739493,082 - 543,700 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFPT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl278,285,203 - 78,328,285 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1278,285,208 - 78,328,288 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2279,770,248 - 79,813,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GFPT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12382,035,258 - 82,086,201 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2382,034,854 - 82,071,828 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607513,422,000 - 13,475,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfpt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473343,058,156 - 43,089,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473343,057,319 - 43,103,568 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gfpt2
237 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:466
Count of miRNA genes:231
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000003770
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum immunoglobulin E level (CMO:0002101)102291826836400810Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)102795762634490668Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 9 1 1 26 4 16
Low 3 34 50 35 18 35 8 11 48 31 25 11 8
Below cutoff 6 6 6

Sequence


RefSeq Acc Id: ENSRNOT00000003770   ⟹   ENSRNOP00000003770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1034,115,052 - 34,161,329 (+)Ensembl
Rnor_6.0 Ensembl1035,279,236 - 35,325,508 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103704   ⟹   ENSRNOP00000089728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1034,126,622 - 34,161,329 (+)Ensembl
RefSeq Acc Id: NM_001002819   ⟹   NP_001002819
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21034,115,052 - 34,161,329 (+)NCBI
Rnor_6.01035,279,237 - 35,325,506 (+)NCBI
Rnor_5.01035,051,132 - 35,097,280 (+)NCBI
RGSC_v3.41035,290,139 - 35,336,286 (+)RGD
Celera1033,471,073 - 33,517,016 (+)RGD
Sequence:
RefSeq Acc Id: XM_039086297   ⟹   XP_038942225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21034,115,005 - 34,160,736 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001002819 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942225 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98630 (Get FASTA)   NCBI Sequence Viewer  
  CAE48379 (Get FASTA)   NCBI Sequence Viewer  
  EDM04236 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003770
  ENSRNOP00000003770.6
  ENSRNOP00000089728.1
GenBank Protein Q4KMC4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001002819   ⟸   NM_001002819
- UniProtKB: Q4KMC4 (UniProtKB/Swiss-Prot),   Q6IE69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003770   ⟸   ENSRNOT00000003770
RefSeq Acc Id: XP_038942225   ⟸   XM_039086297
- Peptide Label: isoform X1
- UniProtKB: Q6IE69 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089728   ⟸   ENSRNOT00000103704
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KMC4-F1-model_v2 AlphaFold Q4KMC4 1-682 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697145
Promoter ID:EPDNEW_R7670
Type:multiple initiation site
Name:Gfpt2_1
Description:glutamine-fructose-6-phosphate transaminase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01035,279,278 - 35,279,338EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303097 AgrOrtholog
BioCyc Gene G2FUF-25266 BioCyc
Ensembl Genes ENSRNOG00000002810 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003770 ENTREZGENE
  ENSRNOT00000003770.7 UniProtKB/TrEMBL
  ENSRNOT00000103704.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7105780 IMAGE-MGC_LOAD
InterPro GATase_2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GFAT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GlmS/AgaS_SIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GlmS/FrlB_SIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GlmS_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ntn_hydrolases_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIS_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:360518 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112555 IMAGE-MGC_LOAD
NCBI Gene 360518 ENTREZGENE
PANTHER GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GATase_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gfpt2 PhenoGen
PROSITE GATASE_TYPE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002810 RatGTEx
Superfamily-SCOP SSF53697 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56235 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A7W8_RAT UniProtKB/TrEMBL
  A0A8L2Q0F7_RAT UniProtKB/TrEMBL
  A6HDY1_RAT UniProtKB/TrEMBL
  GFPT2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6IE69 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-02-14 Gfpt2  glutamine-fructose-6-phosphate transaminase 2      Symbol and Name status set to provisional 70820 PROVISIONAL