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Gene: Flot2 (flotillin 2) Rattus norvegicus
Symbol: Flot2
Name: flotillin 2
Description: Exhibits ionotropic glutamate receptor binding activity and protease binding activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of establishment of T cell polarity; and protein localization to cell periphery. Localizes to the anchored component of presynaptic active zone membrane; flotillin complex; and glutamatergic synapse. Predicted to colocalize with the cortical actin cytoskeleton. Orthologous to human FLOT2 (flotillin 2); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: flotillin-2; MGC93331; REG-1; reggie-1; reggie1-1
Homo sapiens (human) : FLOT2 (flotillin 2)  HGNC  Alliance
Mus musculus (house mouse) : Flot2 (flotillin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flot2 (flotillin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FLOT2 (flotillin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flot2 (flotillin 2)
Sus scrofa (pig) : FLOT2 (flotillin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01065,304,901 - 65,329,332 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01066,303,072 - 66,327,750 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,081,463 - 64,104,166 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11064,095,085 - 64,117,788 (+)NCBI
Celera1061,904,365 - 61,926,029 (+)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Flot2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70993
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-06-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.