Flot1 (flotillin 1) - Rat Genome Database

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Gene: Flot1 (flotillin 1) Rattus norvegicus
Analyze
Symbol: Flot1
Name: flotillin 1
RGD ID: 70991
Description: Enables ionotropic glutamate receptor binding activity and protease binding activity. Predicted to be involved in several processes, including positive regulation of cell-cell adhesion; positive regulation of cellular component organization; and protein localization to membrane. Predicted to act upstream of with a positive effect on plasma membrane raft organization. Predicted to act upstream of or within axonogenesis and regulation of Rho protein signal transduction. Located in caveola. Part of flotillin complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone. Orthologous to human FLOT1 (flotillin 1); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: flotillin-1; Rareg; REG-2; reggie-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2202,917,864 - 2,927,993 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl202,917,137 - 2,927,978 (-)Ensembl
Rnor_6.0203,427,890 - 3,438,418 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,427,880 - 3,438,396 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,524,708 - 5,535,232 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,065,792 - 3,076,166 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,066,008 - 3,169,167 (-)NCBI
Celera20343,778 - 353,887 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
megacolon  (ISO)
Q fever  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
8-Br-cAMP  (ISO)
aconitine  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calciol  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fipronil  (EXP)
folic acid  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
ivermectin  (ISO)
lovastatin  (ISO)
microcystin RR  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
oleic acid  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
pravastatin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
trichloroethene  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:9153235   PMID:11001060   PMID:12370178   PMID:12388596   PMID:12967676   PMID:14581507   PMID:15469992   PMID:15545008   PMID:15934946   PMID:16455755   PMID:16785509  
PMID:17206938   PMID:17218121   PMID:17482312   PMID:17897319   PMID:18000879   PMID:18155272   PMID:18850735   PMID:19056867   PMID:19144954   PMID:19458231   PMID:19946888   PMID:20458337  
PMID:20600927   PMID:20682791   PMID:21119006   PMID:21187433   PMID:21399631   PMID:21413931   PMID:21423176   PMID:21696602   PMID:21700703   PMID:23319823   PMID:23376485   PMID:23533145  
PMID:23983584   PMID:24046456   PMID:24377861   PMID:25204797   PMID:25429154   PMID:25468996   PMID:25732136   PMID:25893292   PMID:27676653   PMID:30452906  


Genomics

Comparative Map Data
Flot1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2202,917,864 - 2,927,993 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl202,917,137 - 2,927,978 (-)Ensembl
Rnor_6.0203,427,890 - 3,438,418 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,427,880 - 3,438,396 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,524,708 - 5,535,232 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,065,792 - 3,076,166 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,066,008 - 3,169,167 (-)NCBI
Celera20343,778 - 353,887 (-)NCBICelera
Cytogenetic Map20p12NCBI
FLOT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,727,709 - 30,742,687 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl630,727,709 - 30,742,732 (-)EnsemblGRCh38hg38GRCh38
GRCh37630,695,486 - 30,710,464 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,803,490 - 30,818,432 (-)NCBINCBI36hg18NCBI36
Build 34630,803,491 - 30,818,432NCBI
Celera632,293,643 - 32,308,593 (-)NCBI
Cytogenetic Map6p21.33NCBI
HuRef630,495,459 - 30,510,242 (-)NCBIHuRef
CHM1_1630,697,639 - 30,712,561 (-)NCBICHM1_1
Flot1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,134,213 - 36,143,681 (+)NCBIGRCm39mm39
GRCm39 Ensembl1736,134,122 - 36,143,683 (+)Ensembl
GRCm381735,823,320 - 35,832,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,823,230 - 35,832,791 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,960,302 - 35,969,732 (+)NCBIGRCm37mm9NCBIm37
MGSCv361735,431,410 - 35,440,840 (+)NCBImm8
Celera1739,333,424 - 39,342,847 (+)NCBICelera
Cytogenetic Map17B1NCBI
Flot1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583713,560 - 729,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955583717,246 - 729,924 (-)NCBIChiLan1.0ChiLan1.0
FLOT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1631,342,026 - 31,357,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,342,033 - 31,357,559 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0630,472,839 - 30,487,809 (-)NCBIMhudiblu_PPA_v0panPan3
FLOT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112517,941 - 528,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12516,032 - 528,637 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12655,207 - 665,931 (-)NCBI
ROS_Cfam_1.012661,078 - 671,802 (-)NCBI
ROS_Cfam_1.0 Ensembl12656,880 - 671,882 (-)Ensembl
UMICH_Zoey_3.112519,006 - 529,724 (-)NCBI
UNSW_CanFamBas_1.012587,853 - 598,598 (-)NCBI
UU_Cfam_GSD_1.012656,440 - 667,178 (-)NCBI
Flot1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494634,021,923 - 34,035,815 (-)NCBI
SpeTri2.0NW_004936837387,012 - 401,076 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLOT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,253,160 - 23,265,106 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,253,157 - 23,265,165 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2726,975,124 - 26,987,109 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FLOT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11741,714,354 - 41,725,820 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1741,714,402 - 41,725,397 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604430,425,408 - 30,437,271 (-)NCBIVero_WHO_p1.0
Flot1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,992,961 - 25,000,463 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D20Yum36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,923,662 - 2,924,126 (+)MAPPERmRatBN7.2
mRatBN7.2202,923,970 - 2,924,126 (+)MAPPERmRatBN7.2
Rnor_6.0203,433,998 - 3,434,548NCBIRnor6.0
Rnor_6.0203,434,393 - 3,434,548NCBIRnor6.0
Rnor_5.0205,531,211 - 5,531,366UniSTSRnor5.0
Rnor_5.0205,530,816 - 5,531,366UniSTSRnor5.0
RGSC_v3.4203,071,900 - 3,072,055UniSTSRGSC3.4
Celera20349,883 - 350,038UniSTS
Cytogenetic Map20p12UniSTS
RH129082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,917,909 - 2,918,078 (+)MAPPERmRatBN7.2
Rnor_6.0203,427,936 - 3,428,104NCBIRnor6.0
Rnor_5.0205,524,754 - 5,524,922UniSTSRnor5.0
RGSC_v3.4203,065,838 - 3,066,006UniSTSRGSC3.4
Celera20343,824 - 343,992UniSTS
RH 3.4 Map2052.42UniSTS
Cytogenetic Map20p12UniSTS
RH131920  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,928,448 - 2,928,631 (+)MAPPERmRatBN7.2
Rnor_6.0203,438,869 - 3,439,051NCBIRnor6.0
Rnor_5.0205,535,687 - 5,535,869UniSTSRnor5.0
RGSC_v3.4203,076,639 - 3,076,821UniSTSRGSC3.4
Celera20354,360 - 354,542UniSTS
RH 3.4 Map2052.72UniSTS
Cytogenetic Map20p12UniSTS
RH140901  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,917,863 - 2,918,014 (+)MAPPERmRatBN7.2
Rnor_6.0203,427,890 - 3,428,040NCBIRnor6.0
Rnor_5.0205,524,708 - 5,524,858UniSTSRnor5.0
RGSC_v3.4203,065,792 - 3,065,942UniSTSRGSC3.4
Celera20343,778 - 343,928UniSTS
RH 3.4 Map2052.32UniSTS
Cytogenetic Map20p12UniSTS
UniSTS:496739  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,928,940 - 2,929,042 (+)MAPPERmRatBN7.2
Rnor_6.0203,439,361 - 3,439,462NCBIRnor6.0
Rnor_5.0205,536,179 - 5,536,280UniSTSRnor5.0
RGSC_v3.4203,077,131 - 3,077,232UniSTSRGSC3.4
Celera20354,852 - 354,953UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:100
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000001098
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 38 50 34 19 34 1 4 74 30 36 11 1
Low 5 7 7 7 7 7 5 5 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001098   ⟹   ENSRNOP00000001098
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,917,864 - 2,927,976 (-)Ensembl
Rnor_6.0 Ensembl203,427,892 - 3,438,389 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl203,427,892 - 3,430,085 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082523
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl203,427,893 - 3,428,625 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083657
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,917,857 - 2,927,678 (-)Ensembl
Rnor_6.0 Ensembl203,427,880 - 3,438,098 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090039   ⟹   ENSRNOP00000071275
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,917,864 - 2,927,976 (-)Ensembl
Rnor_6.0 Ensembl203,427,890 - 3,438,396 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091945   ⟹   ENSRNOP00000068968
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl202,917,137 - 2,927,978 (-)Ensembl
Rnor_6.0 Ensembl203,435,966 - 3,438,360 (-)Ensembl
RefSeq Acc Id: NM_022701   ⟹   NP_073192
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2202,917,864 - 2,927,976 (-)NCBI
Rnor_6.0203,427,890 - 3,438,396 (-)NCBI
Rnor_5.0205,524,708 - 5,535,232 (-)NCBI
RGSC_v3.4203,065,792 - 3,076,166 (-)RGD
Celera20343,778 - 353,887 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256024   ⟹   XP_006256086
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2202,917,864 - 2,927,993 (-)NCBI
Rnor_6.0203,427,890 - 3,438,418 (-)NCBI
Rnor_5.0205,524,708 - 5,535,232 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099052   ⟹   XP_038954980
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2202,917,864 - 2,927,992 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_073192   ⟸   NM_022701
- UniProtKB: Q9Z1E1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256086   ⟸   XM_006256024
- Peptide Label: isoform X1
- UniProtKB: Q9Z1E1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071275   ⟸   ENSRNOT00000090039
RefSeq Acc Id: ENSRNOP00000068968   ⟸   ENSRNOT00000091945
RefSeq Acc Id: ENSRNOP00000001098   ⟸   ENSRNOT00000001098
RefSeq Acc Id: XP_038954980   ⟸   XM_039099052
- Peptide Label: isoform X2
Protein Domains
PHB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1E1-F1-model_v2 AlphaFold Q9Z1E1 1-428 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701306
Promoter ID:EPDNEW_R11825
Type:initiation region
Name:Flot1_1
Description:flotillin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0203,438,341 - 3,438,401EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70991 AgrOrtholog
BioCyc Gene G2FUF-4776 BioCyc
Ensembl Genes ENSRNOG00000000826 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001098 UniProtKB/Swiss-Prot
  ENSRNOP00000068968 UniProtKB/TrEMBL
  ENSRNOP00000071275 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001098 UniProtKB/Swiss-Prot
  ENSRNOT00000090039 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000091945 UniProtKB/TrEMBL
Gene3D-CATH 3.30.479.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598180 IMAGE-MGC_LOAD
InterPro Band_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Band_7/SPFH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flotillin_C UniProtKB/Swiss-Prot
  Flotillin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64665 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72438 IMAGE-MGC_LOAD
NCBI Gene 64665 ENTREZGENE
PANTHER PTHR13806 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Band_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flot UniProtKB/Swiss-Prot
PhenoGen Flot1 PhenoGen
SMART PHB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117892 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JU52_RAT UniProtKB/TrEMBL
  FLOT1_RAT UniProtKB/Swiss-Prot
  Q6MG17_RAT UniProtKB/TrEMBL
  Q9Z1E1 ENTREZGENE
UniProt Secondary Q9Z1E2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Flot1  flotillin 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization enriched at the plasma membrane, micropatches in neurons and in nonneuronal cells 70739
gene_mapping found within the rat major histocompatibility RT1 complex 1300431