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Gene: Mprip (myosin phosphatase Rho interacting protein) Rattus norvegicus
Symbol: Mprip
Name: myosin phosphatase Rho interacting protein
Description: Predicted to have actin binding activity. Involved in maintenance of protein location in cell; negative regulation of myosin-light-chain-phosphatase activity; and positive regulation of protein phosphorylation. Localizes to the stress fiber. Orthologous to human MPRIP (myosin phosphatase Rho interacting protein); INTERACTS WITH ammonium chloride; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: M-rip; MGC114284; Mrip; myosin phosphatase Rho-interacting protein; myosin phosphatase-Rho interacting protein; p116Rip; Rho interacting protein 3; rho-interacting protein 3; Rhoip3; RIP3
Homo sapiens (human) : MPRIP (myosin phosphatase Rho interacting protein)  HGNC  Alliance
Mus musculus (house mouse) : Mprip (myosin phosphatase Rho interacting protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mprip (myosin phosphatase Rho interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : MPRIP (myosin phosphatase Rho interacting protein)
Canis lupus familiaris (dog) : MPRIP (myosin phosphatase Rho interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mprip (myosin phosphatase Rho interacting protein)
Sus scrofa (pig) : MPRIP (myosin phosphatase Rho interacting protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01046,018,397 - 46,133,580 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,018,659 - 46,133,571 (+)Ensembl
Rnor_5.01045,775,202 - 45,890,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,975,683 - 46,090,601 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11045,989,375 - 46,103,686 (+)NCBI
Celera1043,716,586 - 43,830,972 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mprip
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619947
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.