Enables P-type calcium transporter activity and calcium-dependent ATPase activity. Involved in calcium ion transmembrane transport; endoplasmic reticulum calcium ion homeostasis; and liver regeneration. Predicted to be located in organelle membrane and sarcoplasmic reticulum. Predicted to be active in membrane. Biomarker of hypertension. Orthologous to human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil.
[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ATP2A3 mRNA and ESR1 protein affects the reaction [Estradiol results in decreased expression of ATP2A3 mRNA]
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA] and Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA]
[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATP2A3 mRNA
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA] and Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA]
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ATP2A3 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ATP2A3 mRNA
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATP2A3 mRNA
[Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA and [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein