Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Acsl6 (acyl-CoA synthetase long-chain family member 6) Rattus norvegicus
Analyze
Symbol: Acsl6
Name: acyl-CoA synthetase long-chain family member 6
Description: Exhibits long-chain fatty acid-CoA ligase activity and protein homodimerization activity. Involved in several processes, including generation of neurons; organophosphate biosynthetic process; and positive regulation of long-chain fatty acid import across plasma membrane. Localizes to the nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia and leukemia. Orthologous to human ACSL6 (acyl-CoA synthetase long chain family member 6); PARTICIPATES IN fatty acid beta degradation pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; fatty acid metabolic pathway; INTERACTS WITH (S)-nicotine; 6-propyl-2-thiouracil; actinomycin D.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Facl6; fatty acid Coenzyme A ligase, long chain 6; LACS 6; Lacsl; long-chain acyl-CoA synthetase 6; long-chain acyl-CoA synthetase-like; long-chain-fatty-acid--CoA ligase 6; long-chain-fatty-acid--CoA ligase, brain isozyme
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01039,654,771 - 39,717,592 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01039,430,561 - 39,491,346 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,729,805 - 39,778,106 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,743,427 - 39,791,726 (+)NCBI
Celera1037,792,002 - 37,839,268 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acsl6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69403
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.