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Gene: Pfas (phosphoribosylformylglycinamidine synthase) Rattus norvegicus
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Symbol: Pfas
Name: phosphoribosylformylglycinamidine synthase
Description: Predicted to have phosphoribosylformylglycinamidine synthase activity. Involved in glutamine metabolic process; response to drug; and ribonucleoside monophosphate biosynthetic process. Biomarker of hepatocellular carcinoma. Orthologous to human PFAS (phosphoribosylformylglycinamidine synthase); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FGAM synthetase; LOC287420; phosphoribosylformylglycinamidine synthase (FGAR amidotransferase); similar to phosphoribosylformylglycinamidine synthase
Orthologs:
Homo sapiens (human) : PFAS (phosphoribosylformylglycinamidine synthase)  HGNC  Alliance
Mus musculus (house mouse) : Pfas (phosphoribosylformylglycinamidine synthase (FGAR amidotransferase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pfas (phosphoribosylformylglycinamidine synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : PFAS (phosphoribosylformylglycinamidine synthase)
Canis lupus familiaris (dog) : PFAS (phosphoribosylformylglycinamidine synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pfas (phosphoribosylformylglycinamidine synthase)
Sus scrofa (pig) : PFAS (phosphoribosylformylglycinamidine synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01055,571,881 - 55,593,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01055,314,680 - 55,336,185 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,745,617 - 55,761,944 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11055,759,631 - 55,771,591 (-)NCBI
Celera1052,858,284 - 52,874,638 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pfas
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304926
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.