Pfas (phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)) - Rat Genome Database

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Gene: Pfas (phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)) Mus musculus
Analyze
Symbol: Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
RGD ID: 1614154
MGI Page MGI
Description: Predicted to enable phosphoribosylformylglycinamidine synthase activity. Acts upstream of or within anterior head development. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; integumental system; and liver. Orthologous to human PFAS (phosphoribosylformylglycinamidine synthase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4432409B16Rik; FGAM synthase; FGAMS; FGAR amidotransferase; FGAR-AT; FGARAT; formylglycinamide ribonucleotide amidotransferase; formylglycinamide ribotide amidotransferase; formylglycinamide ribotide synthetase; Gm18; phosphoribosylformylglycinamidine synthase; PURL; RP23-153N12.1; S; Sofa
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,876,527 - 68,899,286 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,876,523 - 68,899,286 (-)EnsemblGRCm39 Ensembl
GRCm381168,985,701 - 69,008,460 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,985,697 - 69,008,460 (-)EnsemblGRCm38mm10GRCm38
MGSCv371168,799,203 - 68,821,962 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,803,482 - 68,824,649 (-)NCBIMGSCv36mm8
Celera1175,928,697 - 75,951,460 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
C60 fullerene  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
methidathion  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nickel dichloride  (ISO)
oxaliplatin  (ISO)
p-toluidine  (ISO)
paracetamol  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trimellitic anhydride  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Proliferation-linked increase in phosphoribosylformylglycinamidine synthetase activity (EC 6.3.5.3). Elliott WL and Weber G, Cancer Res. 1984 Jun;44(6):2430-4.
2. Insulin regulatory effects on purine- and pyrimidine metabolism in alloxan diabetic rat liver. Pillwein K, etal., Padiatr Padol. 1988;23(2):135-44.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14681479   PMID:15368895   PMID:16141072  
PMID:16141073   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21917142   PMID:25917818   PMID:26234751   PMID:27590927   PMID:28378742   PMID:29337348   PMID:30333137  
PMID:30457570   PMID:32325033   PMID:36114006   PMID:36293380   PMID:37770184  


Genomics

Comparative Map Data
Pfas
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,876,527 - 68,899,286 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,876,523 - 68,899,286 (-)EnsemblGRCm39 Ensembl
GRCm381168,985,701 - 69,008,460 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,985,697 - 69,008,460 (-)EnsemblGRCm38mm10GRCm38
MGSCv371168,799,203 - 68,821,962 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,803,482 - 68,824,649 (-)NCBIMGSCv36mm8
Celera1175,928,697 - 75,951,460 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.26NCBI
PFAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,247,608 - 8,270,486 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,247,618 - 8,270,491 (+)EnsemblGRCh38hg38GRCh38
GRCh37178,152,607 - 8,173,804 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,093,362 - 8,114,528 (+)NCBINCBI36Build 36hg18NCBI36
Build 34178,093,361 - 8,114,528NCBI
Celera178,181,466 - 8,202,639 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,048,239 - 8,069,519 (+)NCBIHuRef
CHM1_1178,161,523 - 8,182,731 (+)NCBICHM1_1
T2T-CHM13v2.0178,153,834 - 8,176,708 (+)NCBIT2T-CHM13v2.0
Pfas
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,189,157 - 54,210,685 (-)NCBIGRCr8
mRatBN7.21053,690,301 - 53,711,811 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,691,626 - 53,708,420 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,352,061 - 58,370,245 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,840,655 - 57,858,839 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,349,123 - 53,367,092 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,571,881 - 55,593,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,571,118 - 55,589,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,314,680 - 55,336,185 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,745,617 - 55,761,944 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,759,631 - 55,771,591 (-)NCBI
Celera1052,858,284 - 52,874,638 (-)NCBICelera
Cytogenetic Map10q24NCBI
Pfas
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,640,044 - 8,660,979 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,640,044 - 8,660,950 (-)NCBIChiLan1.0ChiLan1.0
PFAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21965,484,101 - 65,504,296 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11770,293,598 - 70,313,731 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01743,389,389 - 43,409,454 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11748,121,601 - 48,141,728 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1748,121,606 - 48,141,720 (-)Ensemblpanpan1.1panPan2
PFAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,055,144 - 33,076,823 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,060,929 - 33,076,287 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,191,282 - 33,212,476 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,158,221 - 33,179,437 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,162,526 - 33,179,478 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,124,973 - 33,146,201 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,080,723 - 33,102,164 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,260,701 - 33,281,894 (+)NCBIUU_Cfam_GSD_1.0
Pfas
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,009,422 - 48,025,476 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,483,689 - 1,501,364 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,483,688 - 1,499,716 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11253,458,401 - 53,477,254 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,933,799 - 55,951,227 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PFAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,618,952 - 7,639,700 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,623,817 - 7,638,594 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605913,760,889 - 13,781,648 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfas
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,836,943 - 10,853,274 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,831,287 - 10,854,526 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pfas
668 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1893
Count of miRNA genes:831
Interacting mature miRNAs:1074
Transcripts:ENSMUST00000021282, ENSMUST00000146490, ENSMUST00000149703, ENSMUST00000152964, ENSMUST00000172915, ENSMUST00000172987, ENSMUST00000173410
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000021282   ⟹   ENSMUSP00000021282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,876,523 - 68,899,286 (-)Ensembl
GRCm38.p6 Ensembl1168,985,697 - 69,008,460 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146490
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,877,286 - 68,881,432 (-)Ensembl
GRCm38.p6 Ensembl1168,986,460 - 68,990,606 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149703   ⟹   ENSMUSP00000133984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,883,808 - 68,885,157 (-)Ensembl
GRCm38.p6 Ensembl1168,992,982 - 68,994,331 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152964   ⟹   ENSMUSP00000121808
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,878,789 - 68,882,175 (-)Ensembl
GRCm38.p6 Ensembl1168,987,963 - 68,991,349 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172915
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,876,526 - 68,885,102 (-)Ensembl
GRCm38.p6 Ensembl1168,985,700 - 68,994,276 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,887,781 - 68,899,277 (-)Ensembl
GRCm38.p6 Ensembl1168,996,955 - 69,008,451 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173410
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1168,881,547 - 68,882,651 (-)Ensembl
GRCm38.p6 Ensembl1168,990,721 - 68,991,825 (-)Ensembl
RefSeq Acc Id: NM_001159519   ⟹   NP_001152991
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391168,876,527 - 68,899,286 (-)NCBI
GRCm381168,985,701 - 69,008,460 (-)ENTREZGENE
MGSCv371168,799,203 - 68,821,962 (-)RGD
Celera1175,928,697 - 75,951,460 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_001152991   ⟸   NM_001159519
- UniProtKB: A4FUJ6 (UniProtKB/Swiss-Prot),   Q6A080 (UniProtKB/Swiss-Prot),   Q5SUR0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000121808   ⟸   ENSMUST00000152964
RefSeq Acc Id: ENSMUSP00000133984   ⟸   ENSMUST00000149703
RefSeq Acc Id: ENSMUSP00000021282   ⟸   ENSMUST00000021282
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SUR0-F1-model_v2 AlphaFold Q5SUR0 1-1337 view protein structure

Promoters
RGD ID:6846918
Promoter ID:MM_ACW:7804
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:PFAS.GSEP07-UNSPLICED,   SPAWSY.ASEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361168,801,531 - 68,802,031 (-)MPROMDB
RGD ID:6821532
Promoter ID:MM_KWN:8014
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:UC007JOT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361168,806,326 - 68,807,032 (-)MPROMDB
RGD ID:6821533
Promoter ID:MM_KWN:8018
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   ES_Cell,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000021282,   UC007JOV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361168,821,644 - 68,822,144 (-)MPROMDB
RGD ID:8675132
Promoter ID:EPDNEW_M15597
Type:initiation region
Name:Pfas_1
Description:Mus musculus phosphoribosylformylglycinamidine synthase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,008,460 - 69,008,520EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2684864 AgrOrtholog
Ensembl Genes ENSMUSG00000020899 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000021282 ENTREZGENE
  ENSMUST00000021282.12 UniProtKB/Swiss-Prot
  ENSMUST00000149703.4 UniProtKB/TrEMBL
  ENSMUST00000152964.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.880 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.650.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphoribosylformylglycinamidine synthase, linker domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Class_I_gatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGAR-AT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PurL_large UniProtKB/Swiss-Prot
  PurL_linker UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PurM-like_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PurM-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PurM-like_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PurS-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:237823 UniProtKB/Swiss-Prot
MGD MGI:2684864 ENTREZGENE
NCBI Gene 237823 ENTREZGENE
PANTHER PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE UniProtKB/Swiss-Prot
  PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE UniProtKB/Swiss-Prot
  PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE UniProtKB/TrEMBL
  PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE UniProtKB/TrEMBL
Pfam AIRS_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGAR-AT_linker UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGAR-AT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GATase_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pfas PhenoGen
PROSITE GATASE_TYPE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GATase_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP FGAM synthase PurL, linker domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55326 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56042 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82697 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A4FUJ6 ENTREZGENE
  F6RUL9_MOUSE UniProtKB/TrEMBL
  G3UY86_MOUSE UniProtKB/TrEMBL
  PUR4_MOUSE UniProtKB/Swiss-Prot
  Q14BH5_MOUSE UniProtKB/TrEMBL
  Q3UTT7_MOUSE UniProtKB/TrEMBL
  Q5SUR0 ENTREZGENE
  Q6A080 ENTREZGENE
  Q8BVW7_MOUSE UniProtKB/TrEMBL
UniProt Secondary A4FUJ6 UniProtKB/Swiss-Prot
  Q6A080 UniProtKB/Swiss-Prot