(S)-colchicine decreases expression ISO RGD:736496 6480464 Colchicine results in decreased expression of MAPT protein CTD PMID:16930453 (Z)-ligustilide decreases phosphorylation ISO RGD:736497 6480464 ligustilide results in decreased phosphorylation of MAPT protein CTD PMID:23973442 1,2-dimethylhydrazine increases expression ISO RGD:736497 6480464 1, 2-Dimethylhydrazine results in increased expression of MAPT mRNA CTD PMID:22206623 1,4-benzoquinone multiple interactions ISO RGD:736496 6480464 quinone promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:16180106 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea multiple interactions ISO RGD:736496 6480464 [N-(4-methoxybenzyl)-N'-(5-nitro-1, 3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] CTD PMID:21715663 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression EXP 6480464 chlorcyclizine results in increased expression of MAPT mRNA CTD PMID:21058326 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:736497 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:15329391 17alpha-ethynylestradiol affects expression ISO RGD:736497 6480464 Ethinyl Estradiol affects the expression of MAPT mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:736497 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAPT mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:736497 6480464 Ethinyl Estradiol results in increased expression of MAPT mRNA CTD PMID:17942748 17beta-estradiol multiple interactions EXP 6480464 [BDNF protein co-treated with MF63 compound co-treated with Estradiol] inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein] more ... CTD PMID:31715309 , PMID:32738378 17beta-estradiol increases phosphorylation ISO RGD:736496 6480464 Estradiol results in increased phosphorylation of MAPT protein CTD PMID:27026707 17beta-estradiol increases expression ISO RGD:736496 6480464 Estradiol results in increased expression of MAPT mRNA, Estradiol results in increased expression of MAPT protein CTD PMID:20579400 , PMID:31614463 17beta-estradiol multiple interactions ISO RGD:736496 6480464 Tamoxifen inhibits the reaction [Estradiol results in increased expression of MAPT protein] CTD PMID:20579400 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:736497 6480464 [Tetrachlorodibenzodioxin affects the methylation of MAPT intron] which results in decreased expression of MAPT mRNA, [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAPT mRNA CTD PMID:17942748 , PMID:33017471 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of MAPT mRNA CTD PMID:32109520 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736496 6480464 Tetrachlorodibenzodioxin results in increased expression of MAPT mRNA CTD PMID:20106945 , PMID:26238291 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:736497 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPT protein CTD PMID:18996433 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736497 6480464 Tetrachlorodibenzodioxin results in increased expression of MAPT mRNA CTD PMID:16922920 , PMID:17942748 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:736497 6480464 2 more ... CTD PMID:18550172 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:19954255 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO RGD:736497 6480464 2 more ... CTD PMID:18550172 2,5-hexanedione decreases expression EXP 6480464 2, 5-hexanedione results in decreased expression of MAPT protein modified form CTD PMID:20554699 2-methyl-6-(phenylethynyl)pyridine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:24395787 2-methylcholine affects expression ISO RGD:736496 6480464 beta-methylcholine affects the expression of MAPT mRNA CTD PMID:21179406 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO RGD:736497 6480464 3 more ... CTD PMID:10051481 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of MAPT mRNA, alpha-Chlorohydrin results in increased expression of MAPT protein CTD PMID:28522335 , PMID:34915118 3-nitropropanoic acid affects localization EXP 6480464 3-nitropropionic acid affects the localization of MAPT protein CTD PMID:17634376 3alpha-hydroxy-5beta-pregnan-20-one increases phosphorylation EXP 6480464 Pregnanolone results in increased phosphorylation of MAPT protein CTD PMID:17443805 3alpha-hydroxy-5beta-pregnan-20-one decreases expression EXP 6480464 Pregnanolone results in decreased expression of MAPT protein CTD PMID:17443805 4-hydroxyphenyl retinamide increases expression ISO RGD:736497 6480464 Fenretinide results in increased expression of MAPT mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide increases expression ISO RGD:736496 6480464 Fenretinide results in increased expression of MAPT mRNA CTD PMID:16570282 5-azacytidine decreases expression ISO RGD:736496 6480464 Azacitidine results in decreased expression of MAPT protein CTD PMID:16930453 5-fluorouracil multiple interactions ISO RGD:736496 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 5-methoxypsoralen multiple interactions ISO RGD:736497 6480464 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] CTD PMID:34428446 5alpha-pregnane-3,20-dione decreases expression EXP 6480464 5-alpha-Dihydroprogesterone results in decreased expression of MAPT protein CTD PMID:17443805 5alpha-pregnane-3,20-dione increases phosphorylation EXP 6480464 5-alpha-Dihydroprogesterone results in increased phosphorylation of MAPT protein CTD PMID:17443805 8-azaguanine decreases expression ISO RGD:736496 6480464 Azaguanine results in decreased expression of MAPT protein CTD PMID:16930453 8-Br-cAMP decreases expression ISO RGD:736496 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MAPT mRNA CTD PMID:22079614 acetamide increases expression EXP 6480464 acetamide results in increased expression of MAPT mRNA CTD PMID:31881176 acrolein increases phosphorylation ISO RGD:736496 6480464 Acrolein results in increased phosphorylation of MAPT protein CTD PMID:12605413 acrolein increases phosphorylation ISO RGD:736497 6480464 Acrolein results in increased phosphorylation of MAPT protein CTD PMID:12605413 acrolein multiple interactions ISO RGD:736497 6480464 Acrolein promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 acrolein multiple interactions ISO RGD:736496 6480464 Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein], SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of MAPT mRNA CTD PMID:28959563 acrylamide increases phosphorylation ISO RGD:736496 6480464 Acrylamide results in increased phosphorylation of MAPT protein CTD PMID:32763439 acrylamide multiple interactions EXP 6480464 calpeptin inhibits the reaction [Acrylamide results in increased expression of MAPT protein] CTD PMID:30096436 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of MAPT protein CTD PMID:30096436 acrylamide decreases expression ISO RGD:736497 6480464 Acrylamide results in decreased expression of MAPT mRNA CTD PMID:29261810 acrylamide increases phosphorylation EXP 6480464 Acrylamide results in increased phosphorylation of MAPT protein CTD PMID:33421551 aflatoxin B1 affects expression ISO RGD:736496 6480464 Aflatoxin B1 affects the expression of MAPT protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:736496 6480464 Aflatoxin B1 results in increased methylation of MAPT intron CTD PMID:30157460 aflatoxin B1 decreases expression ISO RGD:736496 6480464 Aflatoxin B1 results in decreased expression of MAPT mRNA CTD PMID:21641981 , PMID:22100608 Aflatoxin B2 alpha decreases methylation ISO RGD:736496 6480464 aflatoxin B2 results in decreased methylation of MAPT intron CTD PMID:30157460 agmatine multiple interactions ISO RGD:736497 6480464 Agmatine inhibits the reaction [APP protein results in increased expression of MAPT protein] CTD PMID:32522471 albendazole decreases expression ISO RGD:736496 6480464 Albendazole results in decreased expression of MAPT mRNA, Albendazole results in decreased expression of MAPT protein CTD PMID:16930453 alexidine decreases expression ISO RGD:736496 6480464 alexidine results in decreased expression of MAPT protein CTD PMID:16930453 all-trans-retinoic acid affects response to substance ISO RGD:736496 6480464 MAPT protein affects the susceptibility to Tretinoin CTD PMID:16417947 all-trans-retinoic acid decreases expression ISO RGD:736496 6480464 Tretinoin results in decreased expression of MAPT mRNA CTD PMID:33167477 all-trans-retinoic acid increases expression ISO RGD:736496 6480464 Tretinoin results in increased expression of MAPT mRNA more ... CTD PMID:23903816 more ... all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of MAPT protein CTD PMID:17130476 all-trans-retinoic acid multiple interactions ISO RGD:736496 6480464 MAPT protein promotes the reaction [Tretinoin affects the localization of MAPT protein] more ... CTD PMID:16417947 , PMID:26655721 all-trans-retinoic acid multiple interactions ISO RGD:736497 6480464 MAPT protein promotes the reaction [Tretinoin results in increased activity of CASP3 protein] CTD PMID:16417947 aluminium atom increases phosphorylation EXP 6480464 Aluminum results in increased phosphorylation of MAPT protein CTD PMID:17662457 aluminium atom multiple interactions EXP 6480464 [Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA, Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 aluminium sulfate (anhydrous) increases phosphorylation EXP 6480464 aluminum sulfate results in increased phosphorylation of MAPT protein CTD PMID:11388372 aluminium(0) increases phosphorylation EXP 6480464 Aluminum results in increased phosphorylation of MAPT protein CTD PMID:17662457 aluminium(0) multiple interactions EXP 6480464 [Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA, Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of MAPT mRNA CTD PMID:16483693 ammonium chloride decreases expression EXP 6480464 Ammonium Chloride results in decreased expression of MAPT protein modified form CTD PMID:16483693 antimycin A decreases expression ISO RGD:736496 6480464 Antimycin A results in decreased expression of MAPT mRNA CTD PMID:33512557 antirheumatic drug increases expression ISO RGD:736496 6480464 Antirheumatic Agents results in increased expression of MAPT mRNA CTD PMID:24449571 arachidonic acid increases phosphorylation ISO RGD:736496 6480464 Arachidonic Acid results in increased phosphorylation of MAPT protein CTD PMID:12605413 arachidonic acid multiple interactions ISO RGD:736496 6480464 Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein] CTD PMID:12605413 aristolochic acid A decreases expression ISO RGD:736496 6480464 aristolochic acid I results in decreased expression of MAPT mRNA CTD PMID:33212167 arsane affects expression ISO RGD:736496 6480464 Arsenic metabolite affects the expression of MAPT mRNA CTD PMID:17553662 arsane affects methylation ISO RGD:736496 6480464 Arsenic affects the methylation of MAPT gene CTD PMID:25304211 arsenic atom affects expression ISO RGD:736496 6480464 Arsenic metabolite affects the expression of MAPT mRNA CTD PMID:17553662 arsenic atom affects methylation ISO RGD:736496 6480464 Arsenic affects the methylation of MAPT gene CTD PMID:25304211 ascomycin multiple interactions ISO RGD:736496 6480464 [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein CTD PMID:7723735 ascomycin multiple interactions EXP 6480464 [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein CTD PMID:7723735 astemizole affects binding ISO RGD:736496 6480464 Astemizole binds to MAPT protein alternative form CTD PMID:20110603 ATP multiple interactions EXP 6480464 [annonacin results in decreased abundance of Adenosine Triphosphate] which affects the localization of MAPT protein CTD PMID:17634376 benfotiamine multiple interactions ISO RGD:736497 6480464 [benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein more ... CTD PMID:29860433 benfotiamine decreases phosphorylation ISO RGD:736496 6480464 benphothiamine results in decreased phosphorylation of MAPT protein CTD PMID:29860433 benzo[a]pyrene multiple interactions ISO RGD:736497 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of MAPT mRNA] CTD PMID:22228805 benzo[a]pyrene affects methylation ISO RGD:736496 6480464 Benzo(a)pyrene affects the methylation of MAPT 5' UTR CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:736496 6480464 Benzo(a)pyrene results in decreased expression of MAPT mRNA CTD PMID:21871943 more ... benzo[a]pyrene decreases expression ISO RGD:736497 6480464 Benzo(a)pyrene results in decreased expression of MAPT mRNA CTD PMID:23735875 benzo[a]pyrene increases expression ISO RGD:736497 6480464 Benzo(a)pyrene results in increased expression of MAPT mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:736496 6480464 7 more ... CTD PMID:26238291 berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAPT mRNA CTD PMID:18164116 bis(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPT protein CTD PMID:22610992 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 bisphenol A increases methylation ISO RGD:736496 6480464 bisphenol A results in increased methylation of MAPT gene CTD PMID:22576693 bisphenol A decreases methylation ISO RGD:736496 6480464 bisphenol A results in decreased methylation of MAPT gene CTD PMID:31601247 bisphenol A decreases expression ISO RGD:736497 6480464 bisphenol A results in decreased expression of MAPT mRNA, bisphenol A results in decreased expression of MAPT protein CTD PMID:32512148 bisphenol A increases expression ISO RGD:736497 6480464 bisphenol A results in increased expression of MAPT protein modified form CTD PMID:32278051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Genistein] results in increased methylation of MAPT gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MAPT mRNA CTD PMID:30816183 , PMID:34947998 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of MAPT mRNA CTD PMID:25181051 bisphenol A increases phosphorylation ISO RGD:736497 6480464 bisphenol A results in increased phosphorylation of MAPT protein CTD PMID:26779933 , PMID:26923231 bisphenol A decreases expression ISO RGD:736496 6480464 bisphenol A results in decreased expression of MAPT mRNA CTD PMID:22576693 butanal increases expression ISO RGD:736496 6480464 butyraldehyde results in increased expression of MAPT mRNA CTD PMID:26079696 Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 cadmium atom multiple interactions EXP 6480464 [Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA, Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 cadmium atom multiple interactions ISO RGD:736497 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MAPT mRNA, [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MAPT protein CTD PMID:30614199 cadmium dichloride multiple interactions ISO RGD:736497 6480464 [[Cadmium Chloride results in decreased activity of CHRM1 protein] which affects the expression of ACHE mRNA alternative form] which results in increased expression of MAPT protein more ... CTD PMID:26026611 more ... cadmium dichloride increases expression ISO RGD:736497 6480464 Cadmium Chloride results in increased expression of MAPT protein, Cadmium Chloride results in increased expression of MAPT protein modified form CTD PMID:27377441 caffeine affects phosphorylation ISO RGD:736496 6480464 Caffeine affects the phosphorylation of MAPT protein CTD PMID:35688186 calcitriol increases expression ISO RGD:736496 6480464 Calcitriol results in increased expression of MAPT mRNA CTD PMID:26485663 Calpeptin multiple interactions EXP 6480464 calpeptin inhibits the reaction [Acrylamide results in increased expression of MAPT protein] CTD PMID:30096436 camptothecin decreases expression ISO RGD:736496 6480464 Camptothecin results in decreased expression of MAPT mRNA, Camptothecin results in decreased expression of MAPT protein CTD PMID:16930453 cannabidiol affects methylation EXP 6480464 Cannabidiol affects the methylation of MAPT gene CTD PMID:30521419 cannabidiol decreases expression ISO RGD:736496 6480464 Cannabidiol results in decreased expression of MAPT mRNA CTD PMID:28025562 carbon nanotube decreases expression ISO RGD:736497 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 CCCP affects localization EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of MAPT protein CTD PMID:17634376 CGP 52608 multiple interactions ISO RGD:736496 6480464 CGP 52608 promotes the reaction [RORA protein binds to MAPT gene] CTD PMID:28238834 chelidonine decreases expression ISO RGD:736496 6480464 chelidonine results in decreased expression of MAPT protein CTD PMID:16930453 chlordecone decreases expression ISO RGD:736497 6480464 Chlordecone results in decreased expression of MAPT mRNA CTD PMID:33711761 chloroquine affects expression EXP 6480464 Chloroquine affects the expression of MAPT mRNA, Chloroquine affects the expression of MAPT protein CTD PMID:9690670 chloroquine multiple interactions EXP 6480464 Chloroquine affects the localization of and affects the degradation of MAPT protein CTD PMID:9690670 chlorpyrifos increases phosphorylation ISO RGD:736497 6480464 Chlorpyrifos results in increased phosphorylation of MAPT protein CTD PMID:29665406 chlorpyrifos multiple interactions ISO RGD:736497 6480464 BBC3 gene mutant form inhibits the reaction [Chlorpyrifos results in increased phosphorylation of and results in increased expression of MAPT protein] more ... CTD PMID:29665406 , PMID:34289071 cholesterol multiple interactions EXP 6480464 [Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form, Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form] CTD PMID:30695686 ciclopirox decreases expression ISO RGD:736496 6480464 ciclopirox results in decreased expression of MAPT protein CTD PMID:16930453 ciguatoxin CTX1B affects expression ISO RGD:736497 6480464 Ciguatoxins affects the expression of MAPT mRNA CTD PMID:18353800 cilostazol multiple interactions ISO RGD:736497 6480464 cilostazol affects the acetylation of and affects the phosphorylation of MAPT protein, SIRT1 protein affects the reaction [cilostazol affects the acetylation of and affects the phosphorylation of MAPT protein] CTD PMID:24254769 copper atom decreases expression EXP 6480464 Copper results in decreased expression of MAPT mRNA CTD PMID:22465980 copper atom increases phosphorylation ISO RGD:736496 6480464 Copper results in increased phosphorylation of MAPT protein CTD PMID:25671100 copper atom multiple interactions ISO RGD:736497 6480464 Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX1 protein], Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX2 protein] CTD PMID:25352456 copper atom multiple interactions ISO RGD:736496 6480464 [Copper binds to Thiosemicarbazones analog] which results in decreased phosphorylation of MAPT protein more ... CTD PMID:19122148 , PMID:25671100 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of MAPT mRNA CTD PMID:22465980 copper(0) increases phosphorylation ISO RGD:736496 6480464 Copper results in increased phosphorylation of MAPT protein CTD PMID:25671100 copper(0) multiple interactions ISO RGD:736497 6480464 Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX1 protein], Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX2 protein] CTD PMID:25352456 copper(0) multiple interactions ISO RGD:736496 6480464 [Copper binds to Thiosemicarbazones analog] which results in decreased phosphorylation of MAPT protein more ... CTD PMID:19122148 , PMID:25671100 cordycepin multiple interactions EXP 6480464 cordycepin inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPT protein] CTD PMID:30031108 coumarin affects phosphorylation ISO RGD:736496 6480464 coumarin affects the phosphorylation of MAPT protein CTD PMID:35688186 curcumin multiple interactions ISO RGD:736496 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA] CTD PMID:31521693 cyclophosphamide multiple interactions ISO RGD:736496 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 cyclosporin A decreases expression ISO RGD:736496 6480464 Cyclosporine results in decreased expression of MAPT mRNA CTD PMID:20106945 , PMID:27989131 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of MAPT mRNA CTD PMID:22528246 cypermethrin increases expression ISO RGD:736497 6480464 cypermethrin results in increased expression of MAPT protein CTD PMID:26143737 D-aspartic acid multiple interactions EXP 6480464 D-Aspartic Acid results in decreased expression of and affects the phosphorylation of MAPT protein more ... CTD PMID:30822420 D-aspartic acid increases cleavage EXP 6480464 D-Aspartic Acid results in increased cleavage of MAPT protein CTD PMID:30822420 daunorubicin decreases expression ISO RGD:736496 6480464 Daunorubicin results in decreased expression of MAPT mRNA, Daunorubicin results in decreased expression of MAPT protein CTD PMID:16930453 decabromodiphenyl ether increases expression ISO RGD:736497 6480464 decabromobiphenyl ether results in increased expression of MAPT protein CTD PMID:25194327 diaziquone decreases expression ISO RGD:736496 6480464 diaziquone results in decreased expression of MAPT protein CTD PMID:16930453 dibenz[a,h]anthracene increases expression ISO RGD:736496 6480464 1 more ... CTD PMID:16269432 dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 dicrotophos increases expression ISO RGD:736496 6480464 dicrotophos results in increased expression of MAPT mRNA CTD PMID:28302478 diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of MAPT mRNA CTD PMID:17005392 diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 diisononyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 dioxygen multiple interactions ISO RGD:736497 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MAPT mRNA CTD PMID:30529165 dipicolinic acid multiple interactions ISO RGD:736496 6480464 dipicolinic acid promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:31678113 dizocilpine maleate multiple interactions ISO RGD:736496 6480464 Dizocilpine Maleate inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPT protein] CTD PMID:21976409 dizocilpine maleate multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in decreased expression of and affects the phosphorylation of MAPT protein] more ... CTD PMID:30822420 dopamine multiple interactions ISO RGD:736496 6480464 Dopamine metabolite promotes the reaction [MAPT protein binds to MAPT protein], Dopamine promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:16180106 dorsomorphin multiple interactions ISO RGD:736496 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAPT mRNA CTD PMID:27188386 doxorubicin decreases expression ISO RGD:736496 6480464 Doxorubicin results in decreased expression of MAPT protein CTD PMID:16930453 doxorubicin multiple interactions ISO RGD:736496 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form] CTD PMID:30695686 emetine decreases expression ISO RGD:736496 6480464 Emetine results in decreased expression of MAPT protein CTD PMID:16930453 emodin decreases expression ISO RGD:736496 6480464 Emodin results in decreased expression of MAPT mRNA CTD PMID:16045814 endosulfan affects expression ISO RGD:736497 6480464 Endosulfan affects the expression of MAPT protein CTD PMID:26143737 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of MAPT mRNA CTD PMID:29391264 ethanol increases phosphorylation ISO RGD:736497 6480464 Ethanol results in increased phosphorylation of MAPT protein CTD PMID:30143782 ethanol multiple interactions ISO RGD:736497 6480464 Ethanol affects the expression of and affects the splicing of MAPT mRNA, Roscovitine inhibits the reaction [Ethanol results in increased phosphorylation of MAPT protein] CTD PMID:30143782 , PMID:30319688 fasudil multiple interactions EXP 6480464 fasudil inhibits the reaction [methylmercuric chloride results in decreased expression of MAPT protein] CTD PMID:20869980 fenbendazole decreases expression ISO RGD:736496 6480464 Fenbendazole results in decreased expression of MAPT protein CTD PMID:16930453 fisetin multiple interactions ISO RGD:736497 6480464 fisetin inhibits the reaction [Lead results in increased phosphorylation of MAPT protein] CTD PMID:31539617 folic acid multiple interactions ISO RGD:736497 6480464 Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BAD protein modified form] more ... CTD PMID:28422052 , PMID:29068127 folic acid decreases expression ISO RGD:736497 6480464 Folic Acid results in decreased expression of MAPT mRNA CTD PMID:25629700 folic acid decreases expression ISO RGD:736496 6480464 Folic Acid results in decreased expression of MAPT mRNA CTD PMID:21867686 formaldehyde multiple interactions ISO RGD:736496 6480464 Formaldehyde affects the reaction [MAPT protein binds to MAPT protein], Formaldehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17241479 , PMID:17637844 Formyl-N-acetyl-5-methoxykynurenamine multiple interactions EXP 6480464 N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] CTD PMID:31833155 fulvestrant decreases expression ISO RGD:736496 6480464 fulvestrant results in decreased expression of MAPT protein CTD PMID:20579400 genistein multiple interactions EXP 6480464 [bisphenol A co-treated with Genistein] results in increased methylation of MAPT gene CTD PMID:28505145 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of MAPT mRNA CTD PMID:33387578 glyoxal multiple interactions ISO RGD:736497 6480464 Glyoxal promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 griseofulvin increases expression ISO RGD:736497 6480464 Griseofulvin results in increased expression of MAPT mRNA more ... CTD PMID:10051481 harmine multiple interactions ISO RGD:736496 6480464 Harmine inhibits the reaction [DYRK1A protein results in increased phosphorylation of MAPT protein] CTD PMID:21573099 heparin multiple interactions ISO RGD:736496 6480464 Heparin promotes the reaction [MAPT protein binds to MAPT protein], Mercuric Chloride promotes the reaction [Heparin promotes the reaction [MAPT protein binds to MAPT protein]] CTD PMID:20665688 , PMID:31678113 hydrogen peroxide multiple interactions ISO RGD:736496 6480464 4-((alpha-L-rhamnosyloxy)benzyl)isothiocyanate inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA] more ... CTD PMID:28526263 more ... hydrogen peroxide decreases expression ISO RGD:736496 6480464 Hydrogen Peroxide results in decreased expression of MAPT mRNA CTD PMID:31521693 hydrogen peroxide increases phosphorylation ISO RGD:736496 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPT protein CTD PMID:31173752 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of MAPT mRNA CTD PMID:21396975 ionomycin decreases phosphorylation ISO RGD:736497 6480464 Ionomycin results in decreased phosphorylation of MAPT protein CTD PMID:9200503 ionomycin decreases phosphorylation EXP 6480464 Ionomycin results in decreased phosphorylation of MAPT protein CTD PMID:9200503 ionomycin multiple interactions EXP 6480464 Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein] CTD PMID:9200503 ionomycin multiple interactions ISO RGD:736497 6480464 Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein] CTD PMID:9200503 ivermectin decreases expression ISO RGD:736496 6480464 Ivermectin results in decreased expression of MAPT protein CTD PMID:32959892 ketamine increases phosphorylation ISO RGD:736497 6480464 Ketamine results in increased phosphorylation of MAPT protein CTD PMID:20093173 , PMID:31470060 ketamine multiple interactions ISO RGD:736497 6480464 MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein], MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein] CTD PMID:31470060 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:24142891 L-serine multiple interactions EXP 6480464 [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein], Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:30476904 lansoprazole affects binding ISO RGD:736496 6480464 Lansoprazole binds to MAPT protein alternative form CTD PMID:20110603 lasalocid decreases expression ISO RGD:736496 6480464 Lasalocid results in decreased expression of MAPT protein CTD PMID:16930453 lead diacetate multiple interactions EXP 6480464 lead acetate results in decreased expression of and results in increased phosphorylation of MAPT protein more ... CTD PMID:23134599 more ... lead diacetate multiple interactions ISO RGD:736496 6480464 lead acetate results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:27293183 lead diacetate increases phosphorylation EXP 6480464 lead acetate results in increased phosphorylation of MAPT protein CTD PMID:22811615 , PMID:25088297 lead diacetate multiple interactions ISO RGD:736497 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPT protein more ... CTD PMID:24954411 more ... lead diacetate increases expression ISO RGD:736497 6480464 lead acetate results in increased expression of MAPT mRNA CTD PMID:24954411 lead tetraacetate decreases expression ISO RGD:736497 6480464 lead tetraacetate results in decreased expression of MAPT mRNA CTD PMID:20865013 lead(0) affects phosphorylation EXP 6480464 Lead affects the phosphorylation of MAPT protein CTD PMID:22342405 lead(0) multiple interactions ISO RGD:736497 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPT protein, fisetin inhibits the reaction [Lead results in increased phosphorylation of MAPT protein] CTD PMID:31539617 , PMID:31730887 lead(0) increases phosphorylation ISO RGD:736497 6480464 Lead results in increased phosphorylation of MAPT protein CTD PMID:31539617 lead(2+) affects phosphorylation EXP 6480464 Lead affects the phosphorylation of MAPT protein CTD PMID:22342405 lead(2+) multiple interactions ISO RGD:736497 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPT protein, fisetin inhibits the reaction [Lead results in increased phosphorylation of MAPT protein] CTD PMID:31539617 , PMID:31730887 lead(2+) increases phosphorylation ISO RGD:736497 6480464 Lead results in increased phosphorylation of MAPT protein CTD PMID:31539617 leflunomide increases expression ISO RGD:736496 6480464 leflunomide results in increased expression of MAPT mRNA CTD PMID:28988120 liraglutide multiple interactions ISO RGD:736496 6480464 Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein], Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein]] CTD PMID:31173752 lithium atom multiple interactions ISO RGD:736496 6480464 Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 lithium chloride multiple interactions ISO RGD:736497 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]], Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein] CTD PMID:27050422 lithium chloride decreases expression ISO RGD:736496 6480464 Lithium Chloride results in decreased expression of MAPT mRNA CTD PMID:23527032 lithium chloride multiple interactions EXP 6480464 [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein] CTD PMID:20937724 lithium hydride multiple interactions ISO RGD:736496 6480464 Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 losartan multiple interactions EXP 6480464 Losartan inhibits the reaction [AGT protein modified form results in increased phosphorylation of MAPT protein] CTD PMID:22982863 LY294002 multiple interactions ISO RGD:736497 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]] CTD PMID:27050422 malonaldehyde multiple interactions ISO RGD:736497 6480464 Malondialdehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 maneb multiple interactions ISO RGD:736497 6480464 [Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA more ... CTD PMID:23963992 manganese(II) chloride multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein] more ... CTD PMID:20937724 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of MAPT protein CTD PMID:20937724 mebendazole decreases expression ISO RGD:736496 6480464 Mebendazole results in decreased expression of MAPT protein CTD PMID:16930453 melatonin multiple interactions ISO RGD:736497 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA], Melatonin inhibits the reaction [Wortmannin results in increased phosphorylation of MAPT protein] CTD PMID:15842767 , PMID:23963992 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein], Melatonin metabolite inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] CTD PMID:31833155 melatonin multiple interactions ISO RGD:736496 6480464 Melatonin inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPT protein] CTD PMID:10617124 mercury dichloride multiple interactions ISO RGD:736496 6480464 Melatonin inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPT protein] more ... CTD PMID:10617124 , PMID:20665688 mercury dichloride increases phosphorylation ISO RGD:736496 6480464 Mercuric Chloride results in increased phosphorylation of MAPT protein CTD PMID:10617124 methamphetamine multiple interactions ISO RGD:736497 6480464 (1R-(exo more ... CTD PMID:11756511 more ... methamphetamine multiple interactions ISO RGD:736496 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] more ... CTD PMID:29705343 more ... methamphetamine increases phosphorylation EXP 6480464 Methamphetamine results in increased phosphorylation of MAPT protein CTD PMID:29705343 methamphetamine increases phosphorylation ISO RGD:736497 6480464 Methamphetamine results in increased phosphorylation of MAPT protein CTD PMID:29981415 methamphetamine multiple interactions EXP 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] CTD PMID:29705343 methamphetamine increases phosphorylation ISO RGD:736496 6480464 Methamphetamine results in increased phosphorylation of MAPT protein CTD PMID:29705343 , PMID:31270305 methamphetamine increases expression ISO RGD:736497 6480464 Methamphetamine results in increased expression of MAPT mRNA, Methamphetamine results in increased expression of MAPT protein modified form CTD PMID:26307267 , PMID:32278788 methamphetamine decreases expression ISO RGD:736497 6480464 Methamphetamine results in decreased expression of MAPT mRNA CTD PMID:11756511 methylene blue decreases expression ISO RGD:736496 6480464 Methylene Blue results in decreased expression of MAPT protein CTD PMID:16930453 methylene blue multiple interactions ISO RGD:736497 6480464 [Methylene Blue co-treated with MAPT protein mutant form] affects the localization of NFE2L2 protein more ... CTD PMID:24556215 methylene blue decreases phosphorylation ISO RGD:736496 6480464 Methylene Blue results in decreased phosphorylation of MAPT protein modified form CTD PMID:24556215 methylene blue increases expression ISO RGD:736496 6480464 Methylene Blue results in increased expression of MAPT mRNA CTD PMID:16930453 methylglyoxal multiple interactions ISO RGD:736497 6480464 Pyruvaldehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 methylmercury chloride increases expression ISO RGD:736497 6480464 methylmercuric chloride results in increased expression of MAPT mRNA CTD PMID:20061341 methylmercury chloride increases phosphorylation EXP 6480464 methylmercuric chloride results in increased phosphorylation of MAPT protein CTD PMID:28821999 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of MAPT protein CTD PMID:20869980 methylmercury chloride multiple interactions EXP 6480464 exoenzyme C3 more ... CTD PMID:20869980 methylseleninic acid decreases expression ISO RGD:736496 6480464 methylselenic acid results in decreased expression of MAPT mRNA CTD PMID:12517777 microcystin increases phosphorylation EXP 6480464 Microcystins results in increased phosphorylation of MAPT protein CTD PMID:22430071 microcystin LF affects phosphorylation ISO RGD:736497 6480464 microcystin-LF affects the phosphorylation of MAPT protein CTD PMID:21934130 microcystin-LR affects phosphorylation ISO RGD:736497 6480464 cyanoginosin LR affects the phosphorylation of MAPT protein CTD PMID:21934130 microcystin-LR increases phosphorylation EXP 6480464 cyanoginosin LR results in increased phosphorylation of MAPT protein CTD PMID:22000993 , PMID:24142891 microcystin-LR multiple interactions ISO RGD:736496 6480464 SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:23929704 microcystin-LR increases phosphorylation ISO RGD:736496 6480464 cyanoginosin LR results in increased phosphorylation of MAPT protein CTD PMID:23929704 , PMID:27393157 microcystin-LR multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] more ... CTD PMID:22000993 , PMID:24142891 microcystin-LR increases localization EXP 6480464 cyanoginosin LR results in increased localization of MAPT protein CTD PMID:22000993 mono(2-ethylhexyl) phthalate increases expression ISO RGD:736497 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of MAPT mRNA CTD PMID:22401849 morphine increases expression EXP 6480464 Morphine results in increased expression of MAPT mRNA CTD PMID:15183518 Morroniside multiple interactions ISO RGD:736496 6480464 morroniside inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] CTD PMID:26836014 mycophenolic acid decreases expression ISO RGD:736496 6480464 Mycophenolic Acid results in decreased expression of MAPT protein CTD PMID:16930453 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:24142891 N-acetyl-L-cysteine multiple interactions ISO RGD:736496 6480464 Acetylcysteine inhibits the reaction [1, 2-diacetylbenzene results in increased phosphorylation of MAPT protein] CTD PMID:28734998 N-methyl-4-phenylpyridinium increases expression ISO RGD:736497 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPT mRNA CTD PMID:26558463 N-methyl-4-phenylpyridinium affects localization EXP 6480464 1-Methyl-4-phenylpyridinium affects the localization of MAPT protein CTD PMID:17634376 N-methyl-4-phenylpyridinium increases splicing ISO RGD:736496 6480464 1-Methyl-4-phenylpyridinium results in increased splicing of MAPT mRNA CTD PMID:25402454 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:736496 6480464 SRSF2 promotes the reaction [1-Methyl-4-phenylpyridinium results in increased splicing of MAPT mRNA] CTD PMID:25402454 N-methyl-4-phenylpyridinium increases expression ISO RGD:736496 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPT protein alternative form CTD PMID:25402454 N-methyl-D-aspartic acid multiple interactions ISO RGD:736497 6480464 N-Methylaspartate inhibits the reaction [gelsenicine results in increased phosphorylation of MAPT protein] CTD PMID:34389372 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAPT mRNA, Diethylnitrosamine results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:18164116 more ... nickel atom decreases expression ISO RGD:736497 6480464 Nickel results in decreased expression of MAPT mRNA CTD PMID:12540486 nickel atom decreases expression ISO RGD:736496 6480464 Nickel results in decreased expression of MAPT mRNA CTD PMID:24768652 , PMID:25583101 nickel sulfate decreases expression ISO RGD:736497 6480464 nickel sulfate results in decreased expression of MAPT mRNA CTD PMID:16100012 nocodazole decreases expression ISO RGD:736496 6480464 Nocodazole results in decreased expression of MAPT protein CTD PMID:16930453 norethisterone decreases expression ISO RGD:736496 6480464 Norethindrone results in decreased expression of MAPT protein CTD PMID:16930453 okadaic acid affects phosphorylation ISO RGD:736497 6480464 Okadaic Acid affects the phosphorylation of MAPT protein CTD PMID:21934130 , PMID:27050422 okadaic acid increases phosphorylation EXP 6480464 Okadaic Acid results in increased phosphorylation of MAPT protein CTD PMID:26732598 , PMID:7723735 okadaic acid multiple interactions EXP 6480464 [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein more ... CTD PMID:7723735 , PMID:9200503 okadaic acid increases phosphorylation ISO RGD:736496 6480464 Okadaic Acid results in increased phosphorylation of MAPT protein CTD PMID:21715663 more ... okadaic acid multiple interactions ISO RGD:736496 6480464 [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] more ... CTD PMID:21715663 more ... okadaic acid multiple interactions ISO RGD:736497 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]] more ... CTD PMID:27050422 , PMID:9200503 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of MAPT mRNA CTD PMID:25729387 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of MAPT mRNA CTD PMID:25729387 oxidopamine multiple interactions EXP 6480464 Oxidopamine results in increased cleavage of and results in decreased phosphorylation of MAPT protein CTD PMID:12686375 ozone decreases expression ISO RGD:736497 6480464 Ozone results in decreased expression of MAPT mRNA CTD PMID:12763052 ozone multiple interactions ISO RGD:736497 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of MAPT mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of MAPT mRNA CTD PMID:34911549 paclitaxel multiple interactions ISO RGD:736496 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 paclitaxel multiple interactions EXP 6480464 Paclitaxel inhibits the reaction [annonacin affects the localization of MAPT protein] CTD PMID:17634376 paclitaxel decreases expression ISO RGD:736496 6480464 Paclitaxel results in decreased expression of MAPT mRNA, Paclitaxel results in decreased expression of MAPT protein CTD PMID:16930453 paracetamol affects expression ISO RGD:736497 6480464 Acetaminophen affects the expression of MAPT mRNA CTD PMID:17562736 paraquat multiple interactions ISO RGD:736497 6480464 [Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA more ... CTD PMID:22292029 , PMID:23963992 paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of MAPT protein CTD PMID:31715309 , PMID:32738378 paraquat multiple interactions EXP 6480464 [BDNF protein co-treated with MF63 compound co-treated with Estradiol] inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein] more ... CTD PMID:31715309 , PMID:32738378 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of MAPT protein CTD PMID:24521700 pentachlorophenol increases expression ISO RGD:736497 6480464 Pentachlorophenol results in increased expression of MAPT mRNA CTD PMID:23892564 pentanal increases expression ISO RGD:736496 6480464 pentanal results in increased expression of MAPT mRNA CTD PMID:26079696 pentetrazol increases phosphorylation EXP 6480464 Pentylenetetrazole results in increased phosphorylation of MAPT protein CTD PMID:32653415 pentetrazol multiple interactions EXP 6480464 Sitagliptin Phosphate inhibits the reaction [Pentylenetetrazole results in increased phosphorylation of MAPT protein] CTD PMID:32653415 perfluorooctane-1-sulfonic acid increases expression ISO RGD:736497 6480464 perfluorooctane sulfonic acid results in increased expression of MAPT protein CTD PMID:19211617 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of MAPT mRNA CTD PMID:27018931 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 perfluorooctane sulfonic acid results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:27018931 perfluorooctanoic acid increases expression ISO RGD:736497 6480464 perfluorooctanoic acid results in increased expression of MAPT protein CTD PMID:19211617 phenylarsine oxide multiple interactions ISO RGD:736496 6480464 [oxophenylarsine results in increased activity of MARK1 protein] which results in increased phosphorylation of MAPT protein, Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 phenylarsine oxide multiple interactions EXP 6480464 Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 phenylarsine oxide increases phosphorylation ISO RGD:736496 6480464 oxophenylarsine results in increased phosphorylation of MAPT protein CTD PMID:10737602 phenylarsine oxide increases phosphorylation EXP 6480464 oxophenylarsine results in increased phosphorylation of MAPT protein CTD PMID:10737602 PhIP increases expression ISO RGD:736497 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of MAPT protein modified form CTD PMID:32169473 phosgene affects expression ISO RGD:736497 6480464 Phosgene affects the expression of MAPT mRNA CTD PMID:16300373 picoxystrobin decreases expression ISO RGD:736496 6480464 picoxystrobin results in decreased expression of MAPT mRNA CTD PMID:33512557 piericidin A increases phosphorylation ISO RGD:736497 6480464 piericidin A results in increased phosphorylation of MAPT protein polymorphism CTD PMID:25437199 piericidin A increases response to substance ISO RGD:736497 6480464 MAPT protein polymorphism results in increased susceptibility to piericidin A CTD PMID:25437199 pirinixic acid decreases expression ISO RGD:736497 6480464 pirinixic acid results in decreased expression of MAPT mRNA CTD PMID:23811191 podophyllotoxin decreases expression ISO RGD:736496 6480464 Podophyllotoxin results in decreased expression of MAPT protein CTD PMID:16930453 potassium chloride multiple interactions EXP 6480464 Okadaic Acid inhibits the reaction [Potassium Chloride results in decreased phosphorylation of MAPT protein] CTD PMID:9200503 potassium chloride decreases phosphorylation EXP 6480464 Potassium Chloride results in decreased phosphorylation of MAPT protein CTD PMID:9200503 pravastatin affects expression ISO RGD:736496 6480464 Pravastatin affects the expression of MAPT CTD PMID:19461118 pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of MAPT mRNA CTD PMID:27225895 pravastatin decreases expression ISO RGD:736497 6480464 Pravastatin results in decreased expression of MAPT mRNA CTD PMID:27225895 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPT protein] CTD PMID:25088297 progesterone increases phosphorylation EXP 6480464 Progesterone results in increased phosphorylation of MAPT protein CTD PMID:17443805 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of MAPT protein CTD PMID:17443805 propanal increases expression ISO RGD:736496 6480464 propionaldehyde results in increased expression of MAPT mRNA CTD PMID:26079696 pyrithione multiple interactions EXP 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein, GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228 pyrrolidine dithiocarbamate decreases phosphorylation ISO RGD:736497 6480464 pyrrolidine dithiocarbamic acid results in decreased phosphorylation of MAPT protein CTD PMID:17409235 quercetin multiple interactions ISO RGD:736497 6480464 Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein] CTD PMID:27050422 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [aluminum lactate results in increased phosphorylation of MAPT protein] CTD PMID:26493151 quinolinic acid multiple interactions ISO RGD:736496 6480464 Quinolinic Acid promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:31678113 resveratrol multiple interactions ISO RGD:736497 6480464 resveratrol affects the acetylation of and affects the phosphorylation of MAPT protein CTD PMID:24254769 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [APP protein modified form results in increased expression of MAPT protein modified form], resveratrol inhibits the reaction [APP protein modified form results in increased expression of MAPT protein] CTD PMID:25654502 resveratrol decreases expression ISO RGD:736496 6480464 resveratrol results in decreased expression of MAPT mRNA CTD PMID:12569576 resveratrol decreases phosphorylation ISO RGD:736497 6480464 resveratrol results in decreased phosphorylation of MAPT protein CTD PMID:23129026 resveratrol increases expression ISO RGD:736497 6480464 resveratrol results in increased expression of MAPT mRNA CTD PMID:22610192 Ro 31-8220 multiple interactions ISO RGD:736496 6480464 Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein] CTD PMID:12605413 rotenone increases expression EXP 6480464 Rotenone results in increased expression of MAPT protein CTD PMID:16219024 rotenone increases phosphorylation EXP 6480464 Rotenone results in increased phosphorylation of MAPT protein CTD PMID:16219024 rotenone decreases expression ISO RGD:736496 6480464 Rotenone results in decreased expression of MAPT protein CTD PMID:16930453 sarin decreases expression ISO RGD:736496 6480464 Sarin results in decreased expression of MAPT mRNA CTD PMID:19522546 SB 203580 multiple interactions ISO RGD:736496 6480464 SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein], SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:12605413 , PMID:23929704 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [cyanoginosin LR results in increased localization of MAPT protein], SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:22000993 SB 431542 multiple interactions ISO RGD:736496 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAPT mRNA CTD PMID:27188386 scopolamine decreases expression EXP 6480464 Scopolamine results in decreased expression of MAPT mRNA CTD PMID:12818353 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form] CTD PMID:30695686 serpentine asbestos decreases expression ISO RGD:736497 6480464 Asbestos, Serpentine results in decreased expression of MAPT mRNA CTD PMID:16251409 sevoflurane increases phosphorylation ISO RGD:736497 6480464 Sevoflurane results in increased phosphorylation of MAPT protein CTD PMID:35575159 sevoflurane multiple interactions ISO RGD:736497 6480464 APOE protein alternative form inhibits the reaction [Sevoflurane results in increased phosphorylation of MAPT protein] CTD PMID:35575159 silicon dioxide increases phosphorylation ISO RGD:736497 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPT protein CTD PMID:24831964 silicon dioxide increases phosphorylation ISO RGD:736496 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPT protein CTD PMID:24831964 silver atom increases expression ISO RGD:736496 6480464 Silver results in increased expression of MAPT protein modified form CTD PMID:27593553 silver atom decreases expression ISO RGD:736496 6480464 Silver results in decreased expression of MAPT protein CTD PMID:27593553 silver(0) increases expression ISO RGD:736496 6480464 Silver results in increased expression of MAPT protein modified form CTD PMID:27593553 silver(0) decreases expression ISO RGD:736496 6480464 Silver results in decreased expression of MAPT protein CTD PMID:27593553 simvastatin affects expression ISO RGD:736496 6480464 Simvastatin affects the expression of MAPT CTD PMID:19461118 sodium arsenate decreases expression ISO RGD:736497 6480464 sodium arsenate results in decreased expression of MAPT mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO RGD:736497 6480464 sodium arsenite results in decreased expression of MAPT mRNA CTD PMID:23022324 sodium arsenite affects methylation ISO RGD:736496 6480464 sodium arsenite affects the methylation of MAPT gene CTD PMID:28589171 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of MAPT protein CTD PMID:18674524 Soman decreases expression EXP 6480464 Soman results in decreased expression of MAPT mRNA CTD PMID:19281266 staurosporine multiple interactions ISO RGD:736496 6480464 Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 staurosporine multiple interactions EXP 6480464 Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 streptozocin multiple interactions ISO RGD:736497 6480464 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] more ... CTD PMID:20976160 more ... streptozocin increases expression ISO RGD:736497 6480464 Streptozocin results in increased expression of MAPT protein modified form CTD PMID:34428446 streptozocin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] more ... CTD PMID:31833155 streptozocin increases phosphorylation EXP 6480464 Streptozocin results in increased phosphorylation of MAPT protein CTD PMID:31833155 streptozocin increases phosphorylation ISO RGD:736497 6480464 Streptozocin results in increased phosphorylation of MAPT protein CTD PMID:20976160 , PMID:28422052 sunitinib increases expression ISO RGD:736496 6480464 Sunitinib results in increased expression of MAPT mRNA CTD PMID:31533062 tadalafil multiple interactions ISO RGD:736497 6480464 Tadalafil inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] CTD PMID:34428446 tamoxifen multiple interactions ISO RGD:736496 6480464 Tamoxifen inhibits the reaction [Estradiol results in increased expression of MAPT protein] CTD PMID:20579400 tamoxifen affects expression ISO RGD:736497 6480464 Tamoxifen affects the expression of MAPT mRNA CTD PMID:17555576 tamoxifen increases expression ISO RGD:736496 6480464 Tamoxifen results in increased expression of MAPT protein CTD PMID:20579400 tauroursodeoxycholic acid multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [[APP protein modified form results in increased activity of CASP3 protein] which results in increased cleavage of MAPT protein] CTD PMID:18368144 tebufenpyrad decreases expression ISO RGD:736496 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of MAPT mRNA CTD PMID:33512557 testosterone enanthate affects expression ISO RGD:736496 6480464 testosterone enanthate affects the expression of MAPT mRNA CTD PMID:17440010 tetrachloromethane affects expression ISO RGD:736497 6480464 Carbon Tetrachloride affects the expression of MAPT mRNA CTD PMID:17484886 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of MAPT mRNA CTD PMID:16644059 tetrathiomolybdate(2-) multiple interactions ISO RGD:736496 6480464 tetrathiomolybdate inhibits the reaction [Copper results in increased phosphorylation of MAPT protein] CTD PMID:25671100 thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of MAPT protein CTD PMID:35544339 titanium dioxide decreases expression ISO RGD:736497 6480464 titanium dioxide results in decreased expression of MAPT mRNA CTD PMID:23557971 more ... titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of MAPT mRNA CTD PMID:30012374 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of MAPT mRNA CTD PMID:25729387 tributylstannane multiple interactions ISO RGD:736497 6480464 CAST protein inhibits the reaction [tributyltin results in increased degradation of MAPT protein] CTD PMID:33481012 tributylstannane increases cleavage EXP 6480464 tributyltin results in increased cleavage of MAPT protein CTD PMID:23743147 tributylstannane increases degradation ISO RGD:736497 6480464 tributyltin results in increased degradation of MAPT protein CTD PMID:33481012 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of MAPT mRNA CTD PMID:33387578 trichostatin A increases expression ISO RGD:736496 6480464 trichostatin A results in increased expression of MAPT mRNA CTD PMID:24935251 troglitazone decreases expression ISO RGD:736497 6480464 troglitazone results in decreased expression of MAPT mRNA CTD PMID:28973697 Tryptanthrine increases expression ISO RGD:736496 6480464 tryptanthrine results in increased expression of MAPT mRNA CTD PMID:23500671 valproic acid increases methylation ISO RGD:736496 6480464 Valproic Acid results in increased methylation of MAPT gene CTD PMID:29154799 valproic acid multiple interactions ISO RGD:736496 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAPT mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:736496 6480464 Valproic Acid results in increased expression of MAPT, Valproic Acid results in increased expression of MAPT mRNA CTD PMID:19101580 more ... valproic acid affects expression ISO RGD:736496 6480464 Valproic Acid affects the expression of MAPT mRNA CTD PMID:25979313 vancomycin increases expression ISO RGD:736497 6480464 Vancomycin results in increased expression of MAPT mRNA CTD PMID:18930951 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of MAPT mRNA CTD PMID:23034163 vitamin E multiple interactions ISO RGD:736497 6480464 Vitamin E inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein] CTD PMID:15842767 WIN 55212-2 increases expression ISO RGD:736497 6480464 (3R)-((2 more ... CTD PMID:12237329 wortmannin increases phosphorylation ISO RGD:736497 6480464 wortmannin results in increased phosphorylation of MAPT protein CTD PMID:15842767 wortmannin multiple interactions ISO RGD:736496 6480464 Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein]] CTD PMID:31173752 wortmannin multiple interactions ISO RGD:736497 6480464 Melatonin inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein], Vitamin E inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein] CTD PMID:15842767 Y-27632 multiple interactions EXP 6480464 Y 27632 inhibits the reaction [methylmercuric chloride results in decreased expression of MAPT protein] CTD PMID:20869980 zaragozic acid A decreases expression ISO RGD:736497 6480464 squalestatin 1 results in decreased expression of MAPT mRNA CTD PMID:27225895 zaragozic acid A increases expression EXP 6480464 squalestatin 1 results in increased expression of MAPT mRNA CTD PMID:27225895 zinc acetate multiple interactions ISO RGD:736496 6480464 [Zinc Acetate results in decreased abundance of Copper] which results in decreased phosphorylation of MAPT protein CTD PMID:25671100 zinc atom multiple interactions EXP 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein, GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228 zinc(0) multiple interactions EXP 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein, GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228
