(-)-Arctigenin multiple interactions ISO RGD:69005 6480464 arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:21426947 (-)-Arctigenin decreases phosphorylation ISO RGD:737517 6480464 arctigenin results in decreased phosphorylation of STAT3 protein CTD PMID:25380086 (-)-Arctigenin multiple interactions ISO RGD:737517 6480464 Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of STAT3 protein] CTD PMID:25380086 (-)-cotinine increases phosphorylation ISO RGD:737517 6480464 Cotinine results in increased phosphorylation of STAT3 protein CTD PMID:31678612 (-)-demecolcine increases expression ISO RGD:737517 6480464 Demecolcine results in increased expression of STAT3 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:737517 6480464 epigallocatechin gallate results in decreased expression of STAT3 mRNA more ... CTD PMID:20816778 , PMID:22348037 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:737517 6480464 [docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:25655047 (-)-epigallocatechin 3-gallate decreases activity ISO RGD:737517 6480464 epigallocatechin gallate results in decreased activity of STAT3 protein CTD PMID:22348037 (-)-lobeline multiple interactions ISO RGD:737517 6480464 [Lobeline binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein], Lobeline inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 , PMID:20106947 (-)-selegiline multiple interactions ISO RGD:69005 6480464 [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 (20R)-protopanaxadiol affects expression ISO RGD:737517 6480464 protopanaxadiol affects the expression of STAT3 protein CTD PMID:31805304 (25R)-cholest-5-ene-3beta,26-diol multiple interactions ISO RGD:69005 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:28739487 (25R)-cholest-5-ene-3beta,26-diol increases phosphorylation ISO RGD:737517 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:27856279 (25R)-cholest-5-ene-3beta,26-diol multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:27856279 (25R)-cholest-5-ene-3beta,26-diol increases phosphorylation ISO RGD:69005 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:28739487 (R)-lipoic acid multiple interactions ISO RGD:737517 6480464 Thioctic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:19635391 , PMID:28086195 (R)-mevalonic acid multiple interactions ISO RGD:737517 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein] CTD PMID:18453621 (R)-mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]] CTD PMID:16534557 (R)-noradrenaline increases phosphorylation ISO RGD:69005 6480464 Norepinephrine results in increased phosphorylation of STAT3 protein CTD PMID:34609854 (R)-noradrenaline multiple interactions ISO RGD:69005 6480464 [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein], Carnosine inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 (R,R,R)-alpha-tocopherol increases expression EXP 6480464 alpha-Tocopherol results in increased expression of STAT3 mRNA CTD PMID:16908007 (S)-naringenin decreases phosphorylation ISO RGD:737517 6480464 naringenin results in decreased phosphorylation of STAT3 protein CTD PMID:27468969 (S)-nicotine multiple interactions ISO RGD:737517 6480464 [alpha-cyano-(3 more ... CTD PMID:18448488 more ... (S)-nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:34153408 (S)-nicotine affects expression EXP 6480464 Nicotine affects the expression of STAT3 mRNA CTD PMID:29155039 (S)-nicotine multiple interactions EXP 6480464 [Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form more ... CTD PMID:29501575 , PMID:34153408 (S)-nicotine increases response to substance ISO RGD:737517 6480464 STAT3 results in increased susceptibility to Nicotine CTD PMID:20943775 (S)-nicotine increases activity ISO RGD:737517 6480464 Nicotine results in increased activity of STAT3 protein CTD PMID:18448488 (S)-nicotine increases phosphorylation ISO RGD:737517 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:18448488 , PMID:35131329 (S)-nicotine multiple interactions ISO RGD:69005 6480464 HMOX1 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein] more ... CTD PMID:24095726 (S)-nicotine increases response to substance ISO RGD:69005 6480464 STAT3 protein results in increased susceptibility to Nicotine CTD PMID:24095726 (S)-nicotine increases phosphorylation ISO RGD:69005 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:24095726 , PMID:25396421 1,1'-azobis(N,N-dimethylformamide) affects localization ISO RGD:737517 6480464 Diamide affects the localization of STAT3 protein CTD PMID:10364193 1,10-phenanthroline multiple interactions ISO RGD:737517 6480464 1, 10-phenanthroline inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] CTD PMID:10364193 1,2-dimethylhydrazine increases expression ISO RGD:69005 6480464 1, 2-Dimethylhydrazine results in increased expression of STAT3 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:69005 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of STAT3 mRNA] CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of STAT3 mRNA CTD PMID:21983209 , PMID:22841810 1,4-naphthoquinone multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:30871965 1,4-naphthoquinone decreases phosphorylation ISO RGD:737517 6480464 1, 4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein CTD PMID:30871965 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO RGD:737517 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO RGD:69005 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:28801915 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of STAT3 mRNA CTD PMID:17522070 , PMID:30723492 1-naphthyl isothiocyanate increases phosphorylation ISO RGD:69005 6480464 1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein CTD PMID:27853831 1-naphthyl isothiocyanate multiple interactions ISO RGD:69005 6480464 pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein], PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27853831 1-naphthyl isothiocyanate increases expression ISO RGD:69005 6480464 1-Naphthylisothiocyanate results in increased expression of STAT3 mRNA CTD PMID:15913567 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:69005 6480464 15-deoxy-delta(12 more ... CTD PMID:19922793 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein] CTD PMID:12584205 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:737517 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:12847270 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of STAT3 mRNA CTD PMID:16174780 17beta-estradiol multiple interactions ISO RGD:69005 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of STAT3 mRNA] CTD PMID:25210133 17beta-estradiol increases phosphorylation ISO RGD:737517 6480464 Estradiol results in increased phosphorylation of STAT3 protein CTD PMID:17336289 17beta-estradiol multiple interactions ISO RGD:737517 6480464 [Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:14975756 , PMID:17336289 17beta-estradiol increases expression ISO RGD:69005 6480464 Estradiol results in increased expression of STAT3 mRNA CTD PMID:15289156 more ... 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:69005 6480464 [2 more ... CTD PMID:24978599 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:69005 6480464 2 more ... CTD PMID:30294300 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:69005 6480464 Tetrachlorodibenzodioxin results in increased expression of STAT3 mRNA CTD PMID:14708085 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of STAT3 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:69005 6480464 Tetrachlorodibenzodioxin affects the expression of STAT3 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:69005 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of STAT3 protein] more ... CTD PMID:14708085 , PMID:23639249 2,4,6-trinitrobenzenesulfonic acid increases phosphorylation ISO RGD:69005 6480464 Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein CTD PMID:25740948 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] more ... CTD PMID:30365937 , PMID:33522063 2,4,6-trinitrobenzenesulfonic acid increases phosphorylation EXP 6480464 Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein CTD PMID:30365937 , PMID:33522063 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:69005 6480464 stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:25740948 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of STAT3 mRNA CTD PMID:21346803 2,6-dichloroindophenol multiple interactions ISO RGD:737517 6480464 2, 6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] CTD PMID:19635391 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of STAT3 mRNA CTD PMID:21346803 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein], Verapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation EXP 6480464 4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of STAT3 protein CTD PMID:31231976 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions EXP 6480464 rhyncophylline inhibits the reaction [4-iodo-2 more ... CTD PMID:31231976 2-acetamidofluorene multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein, Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:69005 6480464 [Galactosamine co-treated with lipopolysaccharide more ... CTD PMID:28887131 2-butoxyethanol increases expression ISO RGD:69005 6480464 n-butoxyethanol results in increased expression of STAT3 mRNA CTD PMID:19812364 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of STAT3 mRNA CTD PMID:19643169 2-methylcholine affects expression ISO RGD:737517 6480464 beta-methylcholine affects the expression of STAT3 mRNA CTD PMID:21179406 25-hydroxycholesterol multiple interactions EXP 6480464 25-hydroxycholesterol inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:27052460 26-hydroxycholesterol multiple interactions ISO RGD:69005 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:28739487 26-hydroxycholesterol multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:27856279 26-hydroxycholesterol increases phosphorylation ISO RGD:737517 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:27856279 26-hydroxycholesterol increases phosphorylation ISO RGD:69005 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:28739487 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [3 more ... CTD PMID:28284859 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:737517 6480464 3 more ... CTD PMID:28284859 3,3',5,5'-tetraiodothyroacetic acid multiple interactions ISO RGD:737517 6480464 [heteronemin co-treated with tetraiodothyroacetic acid] results in decreased expression of STAT3 protein CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid decreases expression ISO RGD:737517 6480464 tetraiodothyroacetic acid results in decreased expression of STAT3 protein modified form CTD PMID:35151786 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:69005 6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]], bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:24496235 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:737517 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 3-methylcholanthrene multiple interactions ISO RGD:69005 6480464 [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of STAT3 mRNA CTD PMID:25926378 3-Nitrobenzanthrone multiple interactions ISO RGD:737517 6480464 EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein], IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein] CTD PMID:34036453 3-Nitrobenzanthrone increases phosphorylation ISO RGD:737517 6480464 3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein CTD PMID:34036453 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of STAT3 protein modified form], cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:32628957 , PMID:33522063 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of STAT3 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol increases expression ISO RGD:737517 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of STAT3 protein CTD PMID:34186270 4-hydroxynon-2-enal decreases expression ISO RGD:69005 6480464 4-hydroxy-2-nonenal results in decreased expression of STAT3 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:69005 6480464 Fenretinide results in increased expression of STAT3 mRNA CTD PMID:28973697 4-nitrophenol increases expression ISO RGD:69005 6480464 4-nitrophenol results in increased expression of STAT3 mRNA CTD PMID:34673133 4-tert-Octylphenol increases phosphorylation ISO RGD:737517 6480464 4-tert-octylphenol results in increased phosphorylation of STAT3 protein CTD PMID:32466334 5,6,7-trimethoxyflavone multiple interactions ISO RGD:69005 6480464 5 more ... CTD PMID:24161485 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO RGD:737517 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 5-aza-2'-deoxycytidine decreases expression ISO RGD:737517 6480464 Decitabine results in decreased expression of STAT3 protein CTD PMID:19732952 5-aza-2'-deoxycytidine multiple interactions ISO RGD:69005 6480464 Decitabine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein] CTD PMID:24440346 5-azacytidine multiple interactions ISO RGD:737517 6480464 [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein CTD PMID:18443271 5-fluorouracil increases expression ISO RGD:737517 6480464 Fluorouracil results in increased expression of STAT3 mRNA CTD PMID:16557594 5-fluorouracil affects response to substance ISO RGD:737517 6480464 STAT3 protein affects the susceptibility to Fluorouracil CTD PMID:15682485 , PMID:15730734 5-fluorouracil decreases phosphorylation ISO RGD:737517 6480464 Fluorouracil results in decreased phosphorylation of STAT3 protein CTD PMID:18161298 , PMID:18205257 5-formyltetrahydrofolic acid multiple interactions ISO RGD:737517 6480464 FOLR1 protein affects the reaction [Leucovorin results in increased phosphorylation of STAT3 protein] more ... CTD PMID:25841994 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:737517 6480464 6-chloro-2 more ... CTD PMID:24064760 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:31981641 abamectin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of STAT3 mRNA] CTD PMID:34748272 abamectin increases expression EXP 6480464 abamectin results in increased expression of STAT3 mRNA CTD PMID:34748272 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of STAT3 mRNA CTD PMID:31881176 acetic acid increases phosphorylation EXP 6480464 Acetic Acid results in increased phosphorylation of STAT3 protein CTD PMID:35122774 acetic acid multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein], Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:35122774 acetylsalicylic acid multiple interactions ISO RGD:737517 6480464 IL6 protein inhibits the reaction [Aspirin results in decreased expression of STAT3 protein modified form] CTD PMID:19595669 acetylsalicylic acid decreases phosphorylation ISO RGD:69005 6480464 Aspirin results in decreased phosphorylation of STAT3 protein CTD PMID:20886344 acetylsalicylic acid decreases expression ISO RGD:737517 6480464 Aspirin results in decreased expression of STAT3 mRNA, Aspirin results in decreased expression of STAT3 protein modified form CTD PMID:11906190 , PMID:19595669 aflatoxin B1 increases expression ISO RGD:737517 6480464 Aflatoxin B1 results in increased expression of STAT3 mRNA CTD PMID:21641981 , PMID:28943387 Aflatoxin G1 increases phosphorylation ISO RGD:69005 6480464 aflatoxin G1 results in increased phosphorylation of STAT3 protein CTD PMID:25445582 aldehydo-D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 , PMID:24810525 aldehydo-D-glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of STAT3 protein CTD PMID:24810525 aldehydo-D-glucose increases expression ISO RGD:737517 6480464 Glucose results in increased expression of STAT3 protein, Glucose results in increased expression of STAT3 protein modified form CTD PMID:24064760 aldehydo-D-glucose multiple interactions ISO RGD:737517 6480464 6-chloro-2 more ... CTD PMID:24064760 aldehydo-D-glucose multiple interactions ISO RGD:69005 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 , PMID:26064446 all-trans-acitretin decreases expression ISO RGD:737517 6480464 Acitretin results in decreased expression of STAT3 mRNA more ... CTD PMID:16610086 all-trans-retinoic acid affects localization ISO RGD:69005 6480464 Tretinoin affects the localization of STAT3 protein CTD PMID:17026715 all-trans-retinoic acid multiple interactions ISO RGD:69005 6480464 U 0126 inhibits the reaction [Tretinoin affects the localization of STAT3 protein] CTD PMID:17026715 all-trans-retinol affects expression EXP 6480464 Vitamin A affects the expression of STAT3 protein CTD PMID:15963505 allopurinol multiple interactions EXP 6480464 Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]] CTD PMID:21912612 Allylamine increases expression EXP 6480464 Allylamine results in increased expression of STAT3 protein CTD PMID:29355689 alpinumisoflavone multiple interactions ISO RGD:737517 6480464 alpinumisoflavone results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:23850732 alvocidib multiple interactions ISO RGD:737517 6480464 [alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:15039284 alvocidib decreases expression ISO RGD:737517 6480464 alvocidib results in decreased expression of STAT3 mRNA CTD PMID:21239698 AM-251 decreases expression ISO RGD:737517 6480464 AM 251 results in decreased expression of STAT3 mRNA CTD PMID:16500647 AM-251 multiple interactions ISO RGD:737517 6480464 AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of STAT3 protein] CTD PMID:33817834 AM-251 multiple interactions ISO RGD:69005 6480464 AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:27071101 amidotrizoic acid affects expression ISO RGD:737517 6480464 Diatrizoate affects the expression of STAT3 protein modified form CTD PMID:21036957 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of STAT3 mRNA CTD PMID:16483693 amosite asbestos increases expression EXP 6480464 Asbestos, Amosite results in increased expression of STAT3 protein modified form CTD PMID:27083413 amosite asbestos increases activity ISO RGD:69005 6480464 Asbestos, Amosite results in increased activity of STAT3 protein CTD PMID:29112861 amosite asbestos increases expression ISO RGD:69005 6480464 Asbestos, Amosite results in increased expression of STAT3 mRNA CTD PMID:29112861 amphibole asbestos increases expression EXP 6480464 Asbestos, Amphibole results in increased expression of STAT3 protein modified form CTD PMID:27083413 andrographolide decreases activity ISO RGD:737517 6480464 andrographolide results in decreased activity of STAT3 protein CTD PMID:23845849 andrographolide multiple interactions ISO RGD:737517 6480464 andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of STAT3 protein], IL6 protein promotes the reaction [andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of STAT3 protein]] CTD PMID:31128153 andrographolide multiple interactions ISO RGD:69005 6480464 andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of STAT3 protein] CTD PMID:31128153 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:737517 6480464 pyrazolanthrone inhibits the reaction [1 more ... CTD PMID:19429262 more ... anthra[1,9-cd]pyrazol-6(2H)-one increases phosphorylation ISO RGD:737517 6480464 pyrazolanthrone results in increased phosphorylation of STAT3 protein CTD PMID:33030807 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:27174766 antigen multiple interactions ISO RGD:69005 6480464 [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA CTD PMID:28935500 antirheumatic drug decreases expression ISO RGD:737517 6480464 Antirheumatic Agents results in decreased expression of STAT3 mRNA CTD PMID:24449571 apigenin decreases phosphorylation ISO RGD:737517 6480464 Apigenin results in decreased phosphorylation of STAT3 protein CTD PMID:27468969 apigenin multiple interactions ISO RGD:737517 6480464 Apigenin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein] CTD PMID:20153296 arecoline increases expression EXP 6480464 Arecoline results in increased expression of STAT3 protein CTD PMID:34999050 aristolochic acid A increases expression ISO RGD:737517 6480464 aristolochic acid I results in increased expression of STAT3 mRNA CTD PMID:33212167 arsane decreases response to substance ISO RGD:737517 6480464 STAT3 results in decreased susceptibility to Arsenic CTD PMID:15116095 arsane affects phosphorylation ISO RGD:737517 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:35031324 arsane decreases expression ISO RGD:737517 6480464 Arsenic results in decreased expression of STAT3 mRNA CTD PMID:35031324 arsane increases expression ISO RGD:737517 6480464 Arsenic results in increased expression of STAT3 mRNA CTD PMID:27838757 arsane affects phosphorylation ISO RGD:69005 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:27289040 arsane affects methylation ISO RGD:737517 6480464 Arsenic affects the methylation of STAT3 gene CTD PMID:25304211 arsane multiple interactions ISO RGD:737517 6480464 [ATF3 protein affects the susceptibility to Arsenic] which affects the phosphorylation of STAT3 protein more ... CTD PMID:24582688 more ... arsane increases phosphorylation ISO RGD:737517 6480464 Arsenic analog results in increased phosphorylation of STAT3 protein, Arsenic results in increased phosphorylation of STAT3 protein CTD PMID:24582688 , PMID:25559853 arsenic atom decreases response to substance ISO RGD:737517 6480464 STAT3 results in decreased susceptibility to Arsenic CTD PMID:15116095 arsenic atom affects phosphorylation ISO RGD:737517 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:35031324 arsenic atom decreases expression ISO RGD:737517 6480464 Arsenic results in decreased expression of STAT3 mRNA CTD PMID:35031324 arsenic atom increases expression ISO RGD:737517 6480464 Arsenic results in increased expression of STAT3 mRNA CTD PMID:27838757 arsenic atom affects phosphorylation ISO RGD:69005 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:27289040 arsenic atom affects methylation ISO RGD:737517 6480464 Arsenic affects the methylation of STAT3 gene CTD PMID:25304211 arsenic atom multiple interactions ISO RGD:737517 6480464 [ATF3 protein affects the susceptibility to Arsenic] which affects the phosphorylation of STAT3 protein more ... CTD PMID:24582688 more ... arsenic atom increases phosphorylation ISO RGD:737517 6480464 Arsenic analog results in increased phosphorylation of STAT3 protein, Arsenic results in increased phosphorylation of STAT3 protein CTD PMID:24582688 , PMID:25559853 arsenic trichloride increases phosphorylation ISO RGD:737517 6480464 arsenic trichloride results in increased phosphorylation of STAT3 protein CTD PMID:22696236 arsenic trichloride affects phosphorylation ISO RGD:737517 6480464 arsenic trichloride affects the phosphorylation of STAT3 protein CTD PMID:24434654 arsenic trichloride multiple interactions ISO RGD:69005 6480464 MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein], MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] CTD PMID:22696236 arsenic trichloride multiple interactions ISO RGD:737517 6480464 pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] more ... CTD PMID:22696236 , PMID:24434654 arsenite(3-) increases expression ISO RGD:69005 6480464 arsenite results in increased expression of STAT3 mRNA CTD PMID:18191166 arsenous acid multiple interactions ISO RGD:737517 6480464 [Arsenic Trioxide results in decreased activity of NOTCH1 protein] which results in decreased phosphorylation of and results in decreased activity of STAT3 protein more ... CTD PMID:12492118 more ... arsenous acid decreases expression ISO RGD:737517 6480464 Arsenic Trioxide results in decreased expression of STAT3 mRNA, Arsenic Trioxide results in decreased expression of STAT3 protein CTD PMID:23382965 arsenous acid decreases phosphorylation ISO RGD:69005 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:28454374 arsenous acid multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and affects the localization of STAT3 protein] more ... CTD PMID:27174766 arsenous acid affects methylation ISO RGD:737517 6480464 Arsenic Trioxide affects the methylation of STAT3 promoter CTD PMID:26046465 arsenous acid increases phosphorylation ISO RGD:737517 6480464 Arsenic Trioxide results in increased phosphorylation of STAT3 protein CTD PMID:29396848 arsenous acid decreases phosphorylation ISO RGD:737517 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:25196641 more ... aspartame multiple interactions ISO RGD:69005 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of STAT3 mRNA CTD PMID:23783067 aucubin multiple interactions ISO RGD:69005 6480464 aucubin inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:32504734 auranofin decreases expression ISO RGD:737517 6480464 Auranofin results in decreased expression of STAT3 protein modified form CTD PMID:20542334 auranofin multiple interactions ISO RGD:737517 6480464 [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein CTD PMID:20542334 azathioprine multiple interactions ISO RGD:737517 6480464 Azathioprine inhibits the reaction [RAC1 protein binds to STAT3 protein] CTD PMID:12697733 baicalein multiple interactions ISO RGD:737517 6480464 baicalein inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein] CTD PMID:30201452 Bardoxolone methyl decreases phosphorylation ISO RGD:737517 6480464 bardoxolone methyl results in decreased phosphorylation of STAT3 protein CTD PMID:17363558 Bardoxolone methyl multiple interactions ISO RGD:69005 6480464 [bardoxolone methyl co-treated with Dietary Fats] results in decreased expression of STAT3 protein, bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of STAT3 protein] CTD PMID:25637688 , PMID:27417254 benzatropine multiple interactions ISO RGD:737517 6480464 [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 benzo[a]pyrene affects activity ISO RGD:737517 6480464 Benzo(a)pyrene affects the activity of STAT3 protein CTD PMID:20624995 benzo[a]pyrene decreases methylation ISO RGD:737517 6480464 Benzo(a)pyrene results in decreased methylation of STAT3 promoter CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:737517 6480464 Benzo(a)pyrene affects the methylation of STAT3 5' UTR, Benzo(a)pyrene affects the methylation of STAT3 intron CTD PMID:27901495 , PMID:30157460 benzo[a]pyrene multiple interactions ISO RGD:737517 6480464 [AHR protein affects the susceptibility to Benzo(a)pyrene] which affects the phosphorylation of and affects the localization of STAT3 protein more ... CTD PMID:31748929 benzo[a]pyrene increases phosphorylation ISO RGD:69005 6480464 Benzo(a)pyrene results in increased phosphorylation of STAT3 protein CTD PMID:31748929 benzo[a]pyrene increases expression ISO RGD:69005 6480464 Benzo(a)pyrene results in increased expression of STAT3 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:69005 6480464 Benzo(a)pyrene results in decreased expression of STAT3 mRNA CTD PMID:19770486 benzo[a]pyrene diol epoxide I affects expression ISO RGD:737517 6480464 7 more ... CTD PMID:20382639 benzo[e]pyrene increases methylation ISO RGD:737517 6480464 benzo(e)pyrene results in increased methylation of STAT3 intron CTD PMID:30157460 benzoates multiple interactions ISO RGD:737517 6480464 Benzoates analog inhibits the reaction [IL6 protein results in increased activity of STAT3 protein] CTD PMID:29472718 benzoic acid multiple interactions ISO RGD:69005 6480464 Benzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] more ... CTD PMID:26088127 benzoic acid multiple interactions ISO RGD:737517 6480464 Benzoic Acid analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:26088127 beraprost multiple interactions ISO RGD:69005 6480464 beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein] CTD PMID:28887131 berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of STAT3 mRNA] CTD PMID:35121005 Bergenin multiple interactions EXP 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:30365937 beta-Elemonic acid decreases phosphorylation ISO RGD:737517 6480464 beta-elemonic acid results in decreased phosphorylation of STAT3 protein CTD PMID:33878321 betulinic acid multiple interactions ISO RGD:737517 6480464 [Betulinic Acid co-treated with Erlotinib Hydrochloride] results in decreased expression of STAT3 protein modified form CTD PMID:30136359 bis(2-chloroethyl) sulfide increases expression ISO RGD:69005 6480464 Mustard Gas results in increased expression of STAT3 mRNA CTD PMID:18955075 bisphenol A increases expression ISO RGD:737517 6480464 bisphenol A results in increased expression of STAT3 mRNA, bisphenol A results in increased expression of STAT3 protein CTD PMID:21909620 more ... bisphenol A increases expression ISO RGD:69005 6480464 bisphenol A results in increased expression of STAT3 mRNA CTD PMID:32156529 , PMID:32575098 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of STAT3 mRNA CTD PMID:30903817 bisphenol A increases phosphorylation ISO RGD:69005 6480464 bisphenol A results in increased phosphorylation of STAT3 protein CTD PMID:30609183 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of STAT3 gene CTD PMID:28505145 bisphenol A multiple interactions EXP 6480464 Curcumin inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA] CTD PMID:25963729 bisphenol A affects methylation ISO RGD:69005 6480464 bisphenol A affects the methylation of STAT3 gene, bisphenol A affects the methylation of STAT3 promoter CTD PMID:26542749 , PMID:27334623 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of STAT3 mRNA CTD PMID:25181051 , PMID:25963729 bisphenol A increases phosphorylation ISO RGD:737517 6480464 bisphenol A results in increased phosphorylation of STAT3 protein CTD PMID:22343039 more ... bisphenol A multiple interactions ISO RGD:737517 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 more ... bisphenol A multiple interactions ISO RGD:69005 6480464 [bisphenol A co-treated with Dietary Fats] results in increased expression of STAT3 mRNA more ... CTD PMID:16860915 more ... bisphenol A increases response to substance ISO RGD:737517 6480464 STAT3 results in increased susceptibility to bisphenol A CTD PMID:21909620 Bisphenol A diglycidyl ether multiple interactions ISO RGD:69005 6480464 2 more ... CTD PMID:19922793 Bisphenol B increases expression ISO RGD:737517 6480464 bisphenol B results in increased expression of STAT3 protein CTD PMID:34186270 bisphenol F multiple interactions ISO RGD:737517 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 bisphenol F multiple interactions ISO RGD:69005 6480464 alpha-cyano-(3 more ... CTD PMID:32044397 bisphenol F increases phosphorylation ISO RGD:69005 6480464 4, 4'-bisphenol F results in increased phosphorylation of STAT3 protein CTD PMID:32044397 bleomycin A2 multiple interactions ISO RGD:69005 6480464 honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 bleomycin A2 increases expression ISO RGD:69005 6480464 Bleomycin results in increased expression of STAT3 protein modified form CTD PMID:32032644 bortezomib multiple interactions ISO RGD:737517 6480464 [alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein more ... CTD PMID:15039284 more ... bortezomib multiple interactions EXP 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of STAT3 mRNA] CTD PMID:35121005 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of STAT3 mRNA CTD PMID:35121005 BQ 123 multiple interactions ISO RGD:69005 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased phosphorylation of STAT3 protein] CTD PMID:25203536 bucladesine multiple interactions ISO RGD:69005 6480464 STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC protein]] CTD PMID:26064446 butein multiple interactions ISO RGD:737517 6480464 butein affects the reaction [IL6 protein affects the phosphorylation of STAT3 protein] CTD PMID:35130734 butylated hydroxyanisole multiple interactions ISO RGD:737517 6480464 Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17028263 cadmium atom multiple interactions ISO RGD:737517 6480464 Cadmium inhibits the reaction [CNTF protein affects the localization of STAT3 protein], Cadmium inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:16843830 cadmium atom increases phosphorylation ISO RGD:737517 6480464 Cadmium results in increased phosphorylation of STAT3 protein CTD PMID:31154059 cadmium dichloride multiple interactions ISO RGD:737517 6480464 2 more ... CTD PMID:16843830 more ... cadmium dichloride decreases expression ISO RGD:69005 6480464 Cadmium Chloride results in decreased expression of STAT3 protein modified form CTD PMID:33813002 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of STAT3 mRNA CTD PMID:25993096 cadmium dichloride increases phosphorylation ISO RGD:69005 6480464 Cadmium Chloride results in increased phosphorylation of STAT3 protein CTD PMID:23948867 cadmium dichloride increases expression ISO RGD:69005 6480464 Cadmium Chloride results in increased expression of STAT3 mRNA CTD PMID:23948867 cadmium dichloride increases phosphorylation ISO RGD:737517 6480464 Cadmium Chloride results in increased phosphorylation of STAT3 protein CTD PMID:27634459 cadmium dichloride multiple interactions ISO RGD:69005 6480464 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:23376140 , PMID:23948867 cadmium dichloride affects localization ISO RGD:737517 6480464 Cadmium Chloride affects the localization of STAT3 protein modified form CTD PMID:19429262 caffeine affects phosphorylation ISO RGD:737517 6480464 Caffeine affects the phosphorylation of STAT3 protein CTD PMID:35688186 calcitriol increases expression ISO RGD:69005 6480464 Calcitriol results in increased expression of STAT3 CTD PMID:19603526 calyculin a multiple interactions ISO RGD:737517 6480464 [calyculin A co-treated with LIF protein] results in increased phosphorylation of STAT3 protein CTD PMID:22142222 camostat increases phosphorylation ISO RGD:69005 6480464 camostat results in increased phosphorylation of STAT3 protein CTD PMID:25104499 cannabidiol multiple interactions ISO RGD:69005 6480464 Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19910459 cannabidiol increases phosphorylation ISO RGD:737517 6480464 Cannabidiol results in increased phosphorylation of STAT3 protein CTD PMID:32060308 , PMID:33817834 cannabidiol decreases expression ISO RGD:737517 6480464 Cannabidiol results in decreased expression of STAT3 mRNA CTD PMID:27932991 , PMID:31801206 cannabidiol multiple interactions ISO RGD:737517 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of STAT3 mRNA more ... CTD PMID:30096889 more ... capsaicin multiple interactions ISO RGD:737517 6480464 Bortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein] more ... CTD PMID:17505005 capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of STAT3 protein CTD PMID:16788306 capsaicin multiple interactions EXP 6480464 Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein], SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein] CTD PMID:16788306 , PMID:19285962 capsaicin affects localization ISO RGD:737517 6480464 Capsaicin affects the localization of STAT3 protein CTD PMID:17505005 carbamazepine affects expression ISO RGD:737517 6480464 Carbamazepine affects the expression of STAT3 mRNA CTD PMID:24752500 carbidopa multiple interactions ISO RGD:737517 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein], Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 carbidopa multiple interactions ISO RGD:69005 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein], Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 carbofuran increases expression EXP 6480464 Carbofuran results in increased expression of STAT3 mRNA CTD PMID:22240977 , PMID:28982980 carbon nanotube increases expression ISO RGD:69005 6480464 Nanotubes more ... CTD PMID:25554681 more ... carbon nanotube multiple interactions ISO RGD:69005 6480464 [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of STAT3 mRNA CTD PMID:25926378 carbon nanotube increases activity ISO RGD:69005 6480464 Nanotubes, Carbon results in increased activity of STAT3 protein CTD PMID:29112861 carbonyl cyanide p-trifluoromethoxyphenylhydrazone affects response to substance ISO RGD:69005 6480464 STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone CTD PMID:20224768 carnosine multiple interactions ISO RGD:69005 6480464 Carnosine inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of STAT3 mRNA CTD PMID:18500788 celecoxib multiple interactions ISO RGD:69005 6480464 [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein CTD PMID:21268125 ceritinib multiple interactions ISO RGD:737517 6480464 ceritinib analog results in decreased expression of and results in decreased phosphorylation of STAT3 protein CTD PMID:35803438 ceruletide multiple interactions ISO RGD:69005 6480464 (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein] more ... CTD PMID:26390243 , PMID:34423886 ceruletide increases phosphorylation ISO RGD:69005 6480464 Ceruletide results in increased phosphorylation of STAT3 protein CTD PMID:34423886 cetrorelix decreases phosphorylation ISO RGD:737517 6480464 cetrorelix results in decreased phosphorylation of STAT3 protein CTD PMID:21062912 CGP 52608 multiple interactions ISO RGD:737517 6480464 CGP 52608 promotes the reaction [RORA protein binds to STAT3 gene] CTD PMID:28238834 chitin multiple interactions ISO RGD:737517 6480464 [[Aptamers more ... CTD PMID:30041514 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of STAT3 mRNA CTD PMID:23125180 chromium(6+) multiple interactions ISO RGD:737517 6480464 chromium hexavalent ion promotes the reaction [STAT3 protein binds to MIR21 promoter] more ... CTD PMID:17078813 more ... chromium(6+) increases expression ISO RGD:737517 6480464 chromium hexavalent ion results in increased expression of STAT3 protein CTD PMID:25448439 ciglitazone multiple interactions ISO RGD:69005 6480464 2 more ... CTD PMID:19922793 Cirsimarin multiple interactions ISO RGD:69005 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein] CTD PMID:30053449 cisplatin decreases activity ISO RGD:737517 6480464 Cisplatin results in decreased activity of STAT3 protein CTD PMID:20106947 cisplatin increases phosphorylation ISO RGD:737517 6480464 Cisplatin results in increased phosphorylation of STAT3 protein CTD PMID:34560070 cisplatin affects response to substance ISO RGD:737517 6480464 STAT3 protein affects the susceptibility to Cisplatin CTD PMID:34656559 cisplatin increases phosphorylation ISO RGD:69005 6480464 Cisplatin results in increased phosphorylation of STAT3 protein CTD PMID:31306688 more ... cisplatin multiple interactions ISO RGD:69005 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] more ... CTD PMID:31306688 more ... cisplatin increases expression ISO RGD:737517 6480464 Cisplatin results in increased expression of STAT3 mRNA CTD PMID:27392435 cisplatin decreases phosphorylation ISO RGD:737517 127284886 cisplatin decreases phosphorylation of STAT3 protein in stomach RGD cisplatin decreases response to substance ISO RGD:737517 6480464 STAT3 protein results in decreased susceptibility to Cisplatin, STAT3 results in decreased susceptibility to Cisplatin CTD PMID:20106947 more ... cisplatin multiple interactions ISO RGD:737517 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of STAT3 mRNA more ... CTD PMID:20106947 more ... cladribine increases phosphorylation ISO RGD:737517 6480464 Cladribine results in increased phosphorylation of STAT3 protein CTD PMID:21679466 clorgyline multiple interactions ISO RGD:69005 6480464 [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 cobalt dichloride multiple interactions ISO RGD:737517 6480464 [cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter] binds to [APEX1 protein binds to CREBBP promoter]] more ... CTD PMID:15735682 cocaine increases phosphorylation ISO RGD:69005 6480464 Cocaine results in increased phosphorylation of STAT3 protein CTD PMID:29673861 cocaine multiple interactions ISO RGD:69005 6480464 alpha-cyano-(3 more ... CTD PMID:29673861 columbamine multiple interactions ISO RGD:737517 6480464 columbamine inhibits the reaction [CSF2 protein results in increased phosphorylation of STAT3 protein] CTD PMID:23124089 copper atom multiple interactions ISO RGD:737517 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of STAT3 protein CTD PMID:20931265 copper atom increases expression ISO RGD:737517 6480464 Copper results in increased expression of STAT3 mRNA CTD PMID:16391388 copper(0) multiple interactions ISO RGD:737517 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of STAT3 protein CTD PMID:20931265 copper(0) increases expression ISO RGD:737517 6480464 Copper results in increased expression of STAT3 mRNA CTD PMID:16391388 copper(II) sulfate multiple interactions ISO RGD:737517 6480464 [ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein], Copper Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:10364193 , PMID:16896058 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of STAT3 protein CTD PMID:30431687 copper(II) sulfate multiple interactions EXP 6480464 Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] more ... CTD PMID:30431687 copper(II) sulfate increases expression ISO RGD:737517 6480464 Copper Sulfate results in increased expression of STAT3 mRNA CTD PMID:19549813 corosolic acid multiple interactions ISO RGD:69005 6480464 corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein], corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] CTD PMID:26513295 corticosterone multiple interactions ISO RGD:69005 6480464 [Corticosterone co-treated with Isoflurophate] results in increased phosphorylation of STAT3 protein more ... CTD PMID:28500787 coumarin increases phosphorylation ISO RGD:737517 6480464 coumarin results in increased phosphorylation of STAT3 protein CTD PMID:35688186 coumermycin A1 multiple interactions ISO RGD:69005 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased phosphorylation of STAT3 protein]], coumermycin inhibits the reaction [limonin inhibits the reaction [Ceruletide results in increased phosphorylation of STAT3 protein]] CTD PMID:34423886 coumermycin A1 increases phosphorylation ISO RGD:69005 6480464 coumermycin results in increased phosphorylation of STAT3 protein CTD PMID:34423886 coumestrol decreases expression ISO RGD:737517 6480464 Coumestrol results in decreased expression of STAT3 mRNA CTD PMID:19167446 crizotinib decreases phosphorylation ISO RGD:737517 6480464 crizotinib results in decreased phosphorylation of STAT3 protein CTD PMID:22034911 more ... crizotinib multiple interactions ISO RGD:737517 6480464 [[crizotinib results in decreased phosphorylation of MET protein] which results in increased expression of HGF protein] which results in increased phosphorylation of STAT3 protein, MET gene mutant form promotes the reaction [crizotinib results in decreased phosphorylation of STAT3 protein] CTD PMID:22683780 , PMID:22729845 crocin-1 multiple interactions ISO RGD:737517 6480464 crocin affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32886819 Cryptotanshinone decreases phosphorylation ISO RGD:737517 6480464 cryptotanshinone results in decreased phosphorylation of STAT3 protein CTD PMID:28578322 crystal violet multiple interactions ISO RGD:737517 6480464 [Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein] inhibits the reaction [STAT3 protein binds to SOX2 promoter], Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:27373978 cucurbitacin B multiple interactions ISO RGD:69005 6480464 [WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B more ... CTD PMID:24316209 , PMID:29250925 cucurbitacin B affects response to substance ISO RGD:69005 6480464 STAT3 protein affects the susceptibility to cucurbitacin B CTD PMID:24316209 cucurbitacin I multiple interactions ISO RGD:737517 6480464 cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19153190 cucurbitacin I decreases activity ISO RGD:69005 6480464 cucurbitacin I results in decreased activity of STAT3 protein CTD PMID:24316209 cucurbitacin I multiple interactions ISO RGD:69005 6480464 [WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin I CTD PMID:24316209 cucurbitacin I affects response to substance ISO RGD:69005 6480464 STAT3 protein affects the susceptibility to cucurbitacin I CTD PMID:24316209 Cuprizon increases expression ISO RGD:69005 6480464 Cuprizone results in increased expression of STAT3 protein modified form CTD PMID:29864483 Cuprizon multiple interactions ISO RGD:737517 6480464 [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of STAT3 mRNA CTD PMID:26577399 , PMID:27523638 Cuprizon multiple interactions ISO RGD:69005 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of STAT3 protein modified form] CTD PMID:29864483 curcumin multiple interactions ISO RGD:737517 6480464 Bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:16959222 more ... curcumin multiple interactions ISO RGD:69005 6480464 [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:33617879 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of STAT3 mRNA CTD PMID:25963729 curcumin multiple interactions EXP 6480464 Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] more ... CTD PMID:25963729 , PMID:30431687 curcumin increases phosphorylation ISO RGD:69005 6480464 Curcumin results in increased phosphorylation of STAT3 protein CTD PMID:25822711 curcumin decreases phosphorylation ISO RGD:737517 6480464 Curcumin results in decreased phosphorylation of STAT3 protein CTD PMID:19383353 curcumin decreases expression ISO RGD:737517 6480464 Curcumin results in decreased expression of STAT3 mRNA, Curcumin results in decreased expression of STAT3 protein CTD PMID:16959222 , PMID:20816778 cyanidin cation multiple interactions EXP 6480464 cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein] CTD PMID:32044269 cyanidin cation multiple interactions ISO RGD:69005 6480464 [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein, cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:32044269 cyclophosphamide increases phosphorylation EXP 6480464 Cyclophosphamide results in increased phosphorylation of STAT3 protein CTD PMID:19625377 cyclophosphamide decreases phosphorylation ISO RGD:69005 6480464 Cyclophosphamide results in decreased phosphorylation of STAT3 protein CTD PMID:21880982 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein], Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 cyclosporin A increases expression ISO RGD:69005 6480464 Cyclosporine results in increased expression of STAT3 protein CTD PMID:27585667 cyclosporin A increases phosphorylation ISO RGD:69005 6480464 Cyclosporine results in increased phosphorylation of STAT3 protein CTD PMID:22155090 , PMID:23958496 cyclosporin A multiple interactions ISO RGD:69005 6480464 alpha-cyano-(3 more ... CTD PMID:22155090 more ... cytochalasin D multiple interactions ISO RGD:737517 6480464 Cytochalasin D deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 D-glucose multiple interactions ISO RGD:69005 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 , PMID:26064446 D-glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of STAT3 protein CTD PMID:24810525 D-glucose multiple interactions ISO RGD:737517 6480464 6-chloro-2 more ... CTD PMID:24064760 D-glucose increases expression ISO RGD:737517 6480464 Glucose results in increased expression of STAT3 protein, Glucose results in increased expression of STAT3 protein modified form CTD PMID:24064760 D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 , PMID:24810525 dapagliflozin multiple interactions EXP 6480464 dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of STAT3 protein], STAT3 protein promotes the reaction [dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]] CTD PMID:35438302 dapagliflozin increases expression EXP 6480464 dapagliflozin results in increased expression of STAT3 protein CTD PMID:35438302 DDE decreases activity ISO RGD:737517 6480464 Dichlorodiphenyl Dichloroethylene results in decreased activity of STAT3 protein CTD PMID:27589886 DDT multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein] more ... CTD PMID:24820114 DDT affects localization ISO RGD:737517 6480464 DDT affects the localization of STAT3 protein CTD PMID:24820114 deguelin increases activity ISO RGD:737517 6480464 deguelin metabolite results in increased activity of STAT3 protein, deguelin results in increased activity of STAT3 protein CTD PMID:19139008 delphinidin decreases phosphorylation ISO RGD:737517 6480464 delphinidin results in decreased phosphorylation of STAT3 protein CTD PMID:33955636 deoxynivalenol multiple interactions ISO RGD:69005 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 deoxynivalenol increases phosphorylation ISO RGD:69005 6480464 deoxynivalenol results in increased phosphorylation of STAT3 protein CTD PMID:22454431 deoxynivalenol increases expression ISO RGD:69005 6480464 deoxynivalenol results in increased expression of STAT3 mRNA CTD PMID:22454431 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] CTD PMID:30431687 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 dexamethasone multiple interactions ISO RGD:737517 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 dextran sulfate multiple interactions EXP 6480464 [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein, Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein] CTD PMID:19028472 dextran sulfate increases phosphorylation ISO RGD:69005 6480464 Dextran Sulfate results in increased phosphorylation of STAT3 protein CTD PMID:31737179 , PMID:32272095 dextran sulfate increases expression ISO RGD:69005 6480464 Dextran Sulfate results in increased expression of STAT3 protein CTD PMID:26074695 dextran sulfate multiple interactions ISO RGD:69005 6480464 3 more ... CTD PMID:20155626 more ... diarsenic trioxide multiple interactions ISO RGD:737517 6480464 [Arsenic Trioxide results in decreased activity of NOTCH1 protein] which results in decreased phosphorylation of and results in decreased activity of STAT3 protein more ... CTD PMID:12492118 more ... diarsenic trioxide decreases expression ISO RGD:737517 6480464 Arsenic Trioxide results in decreased expression of STAT3 mRNA, Arsenic Trioxide results in decreased expression of STAT3 protein CTD PMID:23382965 diarsenic trioxide decreases phosphorylation ISO RGD:69005 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:28454374 diarsenic trioxide increases phosphorylation ISO RGD:737517 6480464 Arsenic Trioxide results in increased phosphorylation of STAT3 protein CTD PMID:29396848 diarsenic trioxide multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and affects the localization of STAT3 protein] more ... CTD PMID:27174766 diarsenic trioxide decreases phosphorylation ISO RGD:737517 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:25196641 more ... diarsenic trioxide affects methylation ISO RGD:737517 6480464 Arsenic Trioxide affects the methylation of STAT3 promoter CTD PMID:26046465 dibenziodolium multiple interactions ISO RGD:737517 6480464 diphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:19429262 , PMID:20523355 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of STAT3 mRNA CTD PMID:21266533 dibutyl phthalate increases expression ISO RGD:69005 6480464 Dibutyl Phthalate results in increased expression of STAT3 mRNA CTD PMID:17361019 , PMID:21266533 diclofenac increases expression ISO RGD:69005 6480464 Diclofenac results in increased expression of STAT3 mRNA CTD PMID:22285467 , PMID:26934552 diclofenac affects expression ISO RGD:737517 6480464 Diclofenac affects the expression of STAT3 mRNA CTD PMID:24752500 diclofenac increases expression ISO RGD:737517 6480464 Diclofenac results in increased expression of STAT3 mRNA CTD PMID:23506792 diethylstilbestrol increases expression ISO RGD:69005 6480464 Diethylstilbestrol results in increased expression of STAT3 mRNA CTD PMID:15289156 digitoxin multiple interactions ISO RGD:737517 6480464 [Digitoxin co-treated with Oxygen deficiency] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:34717917 Diisodecyl phthalate multiple interactions ISO RGD:69005 6480464 diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein], Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27871981 diisononyl phthalate increases phosphorylation ISO RGD:737517 6480464 diisononyl phthalate results in increased phosphorylation of STAT3 protein CTD PMID:31154059 diisopropyl fluorophosphate multiple interactions ISO RGD:69005 6480464 [Corticosterone co-treated with Isoflurophate] results in increased phosphorylation of STAT3 protein CTD PMID:28500787 dimethyl sulfoxide multiple interactions ISO RGD:737517 6480464 [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 dimethylarsinic acid multiple interactions ISO RGD:737517 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA CTD PMID:23192986 dimethylarsinic acid multiple interactions EXP 6480464 Cacodylic Acid results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:32890875 dinitrogen oxide multiple interactions ISO RGD:69005 6480464 Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein] CTD PMID:15748169 dinitrogen oxide multiple interactions ISO RGD:737517 6480464 Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:15748169 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 dioxygen multiple interactions ISO RGD:737517 6480464 [Digitoxin co-treated with Oxygen deficiency] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:20153296 more ... dioxygen increases phosphorylation ISO RGD:737517 6480464 Oxygen deficiency results in increased phosphorylation of STAT3 protein, Oxygen results in increased phosphorylation of STAT3 protein CTD PMID:19587783 more ... dioxygen increases phosphorylation ISO RGD:69005 6480464 Oxygen results in increased phosphorylation of STAT3 protein CTD PMID:25203536 dioxygen multiple interactions ISO RGD:69005 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 more ... docebenone multiple interactions ISO RGD:69005 6480464 2 more ... CTD PMID:25432964 doxorubicin increases expression ISO RGD:737517 6480464 Doxorubicin results in increased expression of STAT3 mRNA, Doxorubicin results in increased expression of STAT3 protein CTD PMID:16001973 , PMID:17920763 doxorubicin multiple interactions EXP 6480464 dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of STAT3 protein], STAT3 protein promotes the reaction [dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]] CTD PMID:35438302 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of STAT3 protein CTD PMID:35438302 doxorubicin increases phosphorylation ISO RGD:69005 6480464 Doxorubicin results in increased phosphorylation of STAT3 protein CTD PMID:24812279 , PMID:34605108 doxorubicin decreases response to substance ISO RGD:69005 6480464 STAT3 protein results in decreased susceptibility to Doxorubicin CTD PMID:11524388 doxorubicin increases response to substance ISO RGD:69005 6480464 STAT3 gene mutant form results in increased susceptibility to Doxorubicin, STAT3 protein results in increased susceptibility to Doxorubicin CTD PMID:10618415 more ... doxorubicin multiple interactions ISO RGD:69005 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of STAT3 mRNA more ... CTD PMID:10618415 more ... doxorubicin decreases expression ISO RGD:69005 6480464 Doxorubicin results in decreased expression of STAT3 mRNA CTD PMID:10618415 doxorubicin affects response to substance ISO RGD:737517 6480464 STAT3 protein affects the susceptibility to Doxorubicin CTD PMID:17920763 ellagic acid increases expression ISO RGD:737517 6480464 Ellagic Acid results in increased expression of STAT3 mRNA CTD PMID:12002526 ellagic acid decreases expression ISO RGD:737517 6480464 Ellagic Acid results in decreased expression of STAT3 mRNA CTD PMID:20816778 emodin multiple interactions ISO RGD:737517 6480464 Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:23848338 emodin affects localization ISO RGD:737517 6480464 Emodin affects the localization of STAT3 protein CTD PMID:23848338 enalapril multiple interactions EXP 6480464 Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA], Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein] CTD PMID:19958114 endosulfan multiple interactions ISO RGD:737517 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of STAT3 mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:737517 6480464 entinostat results in increased expression of STAT3 mRNA CTD PMID:27188386 enzalutamide multiple interactions ISO RGD:737517 6480464 enzalutamide promotes the reaction [Niclosamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein], Niclosamide inhibits the reaction [STAT3 protein results in decreased susceptibility to enzalutamide] CTD PMID:25970160 enzalutamide decreases response to substance ISO RGD:737517 6480464 STAT3 protein results in decreased susceptibility to enzalutamide CTD PMID:25970160 enzyme inhibitor multiple interactions EXP 6480464 Enzyme Inhibitors inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 protein modified form] CTD PMID:24792324 epoxiconazole decreases expression ISO RGD:69005 6480464 epoxiconazole results in decreased expression of STAT3 mRNA CTD PMID:35436446 eriocitrin decreases phosphorylation ISO RGD:737517 6480464 eriocitrin results in decreased phosphorylation of STAT3 protein CTD PMID:34724282 erlotinib hydrochloride increases phosphorylation ISO RGD:737517 6480464 Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein CTD PMID:23894143 erlotinib hydrochloride decreases expression ISO RGD:737517 6480464 Erlotinib Hydrochloride results in decreased expression of STAT3 protein modified form CTD PMID:30136359 erlotinib hydrochloride increases response to substance ISO RGD:737517 6480464 STAT3 mutant form results in increased susceptibility to Erlotinib Hydrochloride CTD PMID:23894143 erlotinib hydrochloride decreases response to substance ISO RGD:737517 6480464 STAT3 mRNA results in decreased susceptibility to Erlotinib Hydrochloride CTD PMID:23125191 erlotinib hydrochloride multiple interactions ISO RGD:737517 6480464 [Betulinic Acid co-treated with Erlotinib Hydrochloride] results in decreased expression of STAT3 protein modified form more ... CTD PMID:23894143 , PMID:30136359 erythromycin estolate increases expression EXP 6480464 Erythromycin Estolate results in increased expression of STAT3 mRNA CTD PMID:17522070 ethanol multiple interactions EXP 6480464 Ethanol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein] CTD PMID:20052772 ethanol affects splicing ISO RGD:69005 6480464 Ethanol affects the splicing of STAT3 mRNA CTD PMID:30319688 ethosuximide multiple interactions EXP 6480464 Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of STAT3 mRNA] CTD PMID:26420483 ethosuximide increases expression EXP 6480464 Ethosuximide results in increased expression of STAT3 mRNA CTD PMID:26420483 ethyl methanesulfonate increases expression ISO RGD:737517 6480464 Ethyl Methanesulfonate results in increased expression of STAT3 mRNA CTD PMID:23649840 fisetin multiple interactions ISO RGD:737517 6480464 fisetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein] CTD PMID:20153296 fisetin decreases expression ISO RGD:737517 6480464 fisetin results in decreased expression of STAT3 protein CTD PMID:30802432 fluorescein 5-isothiocyanate increases phosphorylation ISO RGD:69005 6480464 Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein CTD PMID:27871981 fluorescein 5-isothiocyanate multiple interactions ISO RGD:69005 6480464 diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein], Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27871981 fluticasone multiple interactions ISO RGD:737517 6480464 Fluticasone inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein], TNF protein inhibits the reaction [Fluticasone inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]] CTD PMID:31822346 folic acid multiple interactions ISO RGD:737517 6480464 alpha-cyano-(3 more ... CTD PMID:25841994 , PMID:29685624 folic acid multiple interactions ISO RGD:69005 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of STAT3 mRNA] CTD PMID:22206623 folic acid increases expression ISO RGD:69005 6480464 Folic Acid results in increased expression of STAT3 mRNA CTD PMID:25629700 formaldehyde increases expression ISO RGD:737517 6480464 Formaldehyde results in increased expression of STAT3 mRNA CTD PMID:23649840 fraxetin decreases phosphorylation ISO RGD:737517 125097526 Fraxetin decreases phosphorylation of STAT3 protein in colorectum RGD fructose increases phosphorylation EXP 6480464 Fructose results in increased phosphorylation of STAT3 protein CTD PMID:22426011 fructose decreases phosphorylation EXP 6480464 Fructose results in decreased phosphorylation of STAT3 protein CTD PMID:23533474 fructose multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:22426011 , PMID:23533474 fulvestrant multiple interactions ISO RGD:69005 6480464 Fulvestrant inhibits the reaction [4, 4'-bisphenol F results in increased phosphorylation of STAT3 protein] CTD PMID:32044397 fulvestrant decreases phosphorylation ISO RGD:69005 6480464 Fulvestrant results in decreased phosphorylation of STAT3 protein CTD PMID:32044397 fulvestrant multiple interactions ISO RGD:737517 6480464 Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:28284859 more ... galangin multiple interactions ISO RGD:737517 6480464 galangin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein] CTD PMID:20153296 galaxolide increases expression ISO RGD:737517 6480464 galaxolide results in increased expression of STAT3 mRNA CTD PMID:34687775 galaxolide multiple interactions ISO RGD:737517 6480464 [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of STAT3 mRNA CTD PMID:34687775 Ganoderic acid A multiple interactions ISO RGD:69005 6480464 ganoderic acid A inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein] CTD PMID:34029542 Garcinol decreases expression ISO RGD:737517 151667907 garcinol decreases expression of STAT3 protein in xenograft glioblastoma tumor RGD gefitinib multiple interactions ISO RGD:737517 6480464 gefitinib inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein], gefitinib inhibits the reaction [EGF results in increased phosphorylation of STAT3 protein] CTD PMID:19318490 , PMID:21787763 gefitinib multiple interactions ISO RGD:69005 6480464 gefitinib inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA], gefitinib inhibits the reaction [Cadmium Chloride results in increased phosphorylation of STAT3 protein] CTD PMID:23948867 gemcitabine decreases activity ISO RGD:737517 6480464 Gemcitabine results in decreased activity of STAT3 protein CTD PMID:22348037 genistein increases expression ISO RGD:69005 6480464 Genistein results in increased expression of STAT3 mRNA CTD PMID:15289156 genistein multiple interactions ISO RGD:737517 6480464 Genistein inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of STAT3 protein], Genistein inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] CTD PMID:10364193 , PMID:33396024 genistein decreases expression ISO RGD:69005 6480464 Genistein results in decreased expression of STAT3 mRNA CTD PMID:21048042 genistein decreases expression ISO RGD:737517 6480464 Genistein results in decreased expression of STAT3 mRNA CTD PMID:20816778 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of STAT3 mRNA CTD PMID:22061828 , PMID:33387578 Ginkgoic acid decreases phosphorylation ISO RGD:737517 127284886 Ginkgoic acid decreases phosphorylation of STAT3 protein in stomach RGD glafenine increases expression EXP 6480464 Glafenine results in increased expression of STAT3 mRNA CTD PMID:24136188 glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 , PMID:24810525 glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of STAT3 protein CTD PMID:24810525 glucose increases expression ISO RGD:737517 6480464 Glucose results in increased expression of STAT3 protein, Glucose results in increased expression of STAT3 protein modified form CTD PMID:24064760 glucose multiple interactions ISO RGD:737517 6480464 6-chloro-2 more ... CTD PMID:24064760 glucose multiple interactions ISO RGD:69005 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 , PMID:26064446 glutathione multiple interactions ISO RGD:737517 6480464 Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:16896058 glutathione affects abundance ISO RGD:69005 6480464 STAT3 protein affects the abundance of Glutathione CTD PMID:20224768 Glutathione ethyl ester multiple interactions EXP 6480464 S-ethyl glutathione inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 mRNA] CTD PMID:24792324 glycine betaine multiple interactions EXP 6480464 Betaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein] CTD PMID:25080425 glyphosate decreases expression ISO RGD:737517 6480464 glyphosate results in decreased expression of STAT3 mRNA CTD PMID:31295307 gold atom increases expression ISO RGD:69005 6480464 Gold results in increased expression of STAT3 mRNA CTD PMID:22155353 gold atom multiple interactions ISO RGD:69005 6480464 [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA CTD PMID:22155353 gold(0) increases expression ISO RGD:69005 6480464 Gold results in increased expression of STAT3 mRNA CTD PMID:22155353 gold(0) multiple interactions ISO RGD:69005 6480464 [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA CTD PMID:22155353 GSK690693 multiple interactions ISO RGD:737517 6480464 GSK690693 promotes the reaction [1, 4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein] CTD PMID:30871965 GW 3965 multiple interactions EXP 6480464 GW 3965 inhibits the reaction [IL6 protein results in increased expression of STAT3 protein modified form] CTD PMID:27052460 halothane multiple interactions ISO RGD:69005 6480464 Halothane results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:24598351 halothane increases expression ISO RGD:69005 6480464 Halothane results in increased expression of STAT3 mRNA CTD PMID:24598351 hesperetin multiple interactions EXP 6480464 hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:33522063 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of STAT3 mRNA] CTD PMID:34748272 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of STAT3 mRNA CTD PMID:21905055 hexadecanoic acid decreases phosphorylation ISO RGD:737517 6480464 Palmitic Acid results in decreased phosphorylation of STAT3 protein CTD PMID:28073184 Hexamethonium multiple interactions ISO RGD:737517 6480464 Hexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 , PMID:20106947 Hexamethonium multiple interactions EXP 6480464 Hexamethonium inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form] CTD PMID:29501575 Honokiol multiple interactions ISO RGD:69005 6480464 honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 Honokiol multiple interactions ISO RGD:737517 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of STAT3 protein modified form] CTD PMID:32032644 hydrogen peroxide multiple interactions ISO RGD:737517 6480464 1 more ... CTD PMID:10364193 more ... hydrogen peroxide increases phosphorylation ISO RGD:737517 6480464 Hydrogen Peroxide results in increased phosphorylation of STAT3 protein CTD PMID:17028263 hydrogen peroxide increases ubiquitination ISO RGD:737517 6480464 Hydrogen Peroxide results in increased ubiquitination of STAT3 protein CTD PMID:24657799 hydrogen peroxide multiple interactions ISO RGD:69005 6480464 Hydrogen Peroxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein] CTD PMID:15748169 hydroxamic acid multiple interactions ISO RGD:737517 6480464 Hydroxamic Acids analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein], Hydroxamic Acids analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:26088127 hydroxamic acid multiple interactions ISO RGD:69005 6480464 Hydroxamic Acids analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] more ... CTD PMID:26088127 imiquimod increases expression ISO RGD:69005 6480464 imiquimod results in increased expression of STAT3 mRNA CTD PMID:26149470 indometacin multiple interactions ISO RGD:69005 6480464 [Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein more ... CTD PMID:21268125 indometacin multiple interactions ISO RGD:737517 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 indoxyl sulfate multiple interactions ISO RGD:69005 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein], Indican results in increased phosphorylation of and results in increased activity of STAT3 protein CTD PMID:23639249 Interferon beta-1b multiple interactions ISO RGD:737517 6480464 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside inhibits the reaction [Interferon beta-1b results in increased phosphorylation of STAT3 protein] CTD PMID:29031523 Interferon beta-1b increases phosphorylation ISO RGD:737517 6480464 Interferon beta-1b results in increased phosphorylation of STAT3 protein CTD PMID:29031523 iomeprol affects expression ISO RGD:737517 6480464 iomeprol affects the expression of STAT3 protein modified form CTD PMID:21036957 iron(2+) sulfate (anhydrous) multiple interactions ISO RGD:737517 6480464 [ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] CTD PMID:10364193 isoliquiritigenin multiple interactions ISO RGD:69005 6480464 isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein] CTD PMID:25026504 isoorientin decreases expression ISO RGD:737517 6480464 homoorientin results in decreased expression of STAT3 protein modified form CTD PMID:34019859 isoorientin decreases phosphorylation ISO RGD:737517 6480464 homoorientin results in decreased phosphorylation of STAT3 protein CTD PMID:34019859 isoprenaline affects localization EXP 6480464 Isoproterenol affects the localization of STAT3 protein CTD PMID:19299911 isoprenaline multiple interactions ISO RGD:69005 6480464 STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]] CTD PMID:31712309 isoprenaline multiple interactions ISO RGD:737517 6480464 STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol] CTD PMID:31712309 isoprenaline increases phosphorylation EXP 6480464 Isoproterenol results in increased phosphorylation of STAT3 protein CTD PMID:25080425 isoprenaline increases expression ISO RGD:69005 6480464 Isoproterenol results in increased expression of STAT3 mRNA CTD PMID:21335049 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of STAT3, Isoproterenol results in increased expression of STAT3 protein CTD PMID:19299911 , PMID:29355689 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA more ... CTD PMID:19299911 more ... ivermectin decreases expression ISO RGD:737517 6480464 Ivermectin results in decreased expression of STAT3 protein CTD PMID:32959892 ivermectin decreases phosphorylation ISO RGD:737517 6480464 Ivermectin results in decreased phosphorylation of STAT3 protein CTD PMID:34904774 ivermectin multiple interactions ISO RGD:737517 6480464 AZD 1480 inhibits the reaction [SLC2A4 protein inhibits the reaction [Ivermectin results in decreased phosphorylation of STAT3 protein]], SLC2A4 protein inhibits the reaction [Ivermectin results in decreased phosphorylation of STAT3 protein] CTD PMID:34904774 kurarinol multiple interactions ISO RGD:69005 6480464 kurarinol inhibits the reaction [STAT3 protein binds to BCL2L1 promoter] CTD PMID:24997323 kurarinol decreases phosphorylation ISO RGD:69005 6480464 kurarinol results in decreased phosphorylation of STAT3 protein CTD PMID:24997323 kurarinol multiple interactions ISO RGD:737517 6480464 kurarinol inhibits the reaction [STAT3 protein binds to BCL2L1 promoter], STAT3 protein inhibits the reaction [kurarinol results in increased activity of CASP3 protein] CTD PMID:24997323 kurarinol decreases phosphorylation ISO RGD:737517 6480464 kurarinol results in decreased phosphorylation of STAT3 protein CTD PMID:24997323 L-arginine multiple interactions ISO RGD:69005 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:34423886 L-arginine increases phosphorylation ISO RGD:69005 6480464 Arginine results in increased phosphorylation of STAT3 protein CTD PMID:34423886 L-ascorbic acid multiple interactions ISO RGD:737517 6480464 Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:16896058 L-ascorbic acid affects expression ISO RGD:737517 6480464 Ascorbic Acid affects the expression of STAT3 mRNA CTD PMID:30597948 L-mimosine increases phosphorylation EXP 6480464 Mimosine results in increased phosphorylation of STAT3 protein CTD PMID:25469848 lapatinib multiple interactions ISO RGD:737517 6480464 Lapatinib inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of STAT3 protein]], Lapatinib inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein] CTD PMID:32890875 , PMID:33396024 lead diacetate increases phosphorylation ISO RGD:737517 6480464 lead acetate results in increased phosphorylation of STAT3 protein CTD PMID:26542248 lead(0) increases expression ISO RGD:69005 6480464 Lead results in increased expression of STAT3 mRNA CTD PMID:35760230 lead(2+) increases expression ISO RGD:69005 6480464 Lead results in increased expression of STAT3 mRNA CTD PMID:35760230 leflunomide increases expression ISO RGD:737517 6480464 leflunomide results in increased expression of STAT3 mRNA CTD PMID:28988120 levofloxacin increases expression EXP 6480464 Levofloxacin results in increased expression of STAT3 mRNA CTD PMID:24136188 limonin multiple interactions ISO RGD:69005 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:34423886 linagliptin multiple interactions ISO RGD:69005 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of STAT3 protein modified form] CTD PMID:29864483 linagliptin multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:35122774 lipoic acid multiple interactions ISO RGD:737517 6480464 Thioctic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:19635391 , PMID:28086195 lipopolysaccharide increases activity ISO RGD:737517 6480464 Lipopolysaccharides results in increased activity of STAT3 protein CTD PMID:21586572 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of STAT3 protein CTD PMID:35279615 lipopolysaccharide increases phosphorylation ISO RGD:737517 6480464 Lipopolysaccharides results in increased phosphorylation of STAT3 protein CTD PMID:32583487 lipopolysaccharide increases response to substance ISO RGD:69005 6480464 STAT3 gene mutant form results in increased susceptibility to Lipopolysaccharides, STAT3 results in increased susceptibility to Lipopolysaccharides CTD PMID:15781265 , PMID:25429137 lipopolysaccharide increases phosphorylation ISO RGD:69005 6480464 Lipopolysaccharides results in increased phosphorylation of STAT3 protein CTD PMID:21262334 more ... lipopolysaccharide increases expression ISO RGD:69005 6480464 Lipopolysaccharides results in increased expression of STAT3 mRNA CTD PMID:10975854 more ... lipopolysaccharide increases activity ISO RGD:69005 6480464 [Lipopolysaccharides results in increased activity of JAK2 protein] which results in increased activity of STAT3 protein, Lipopolysaccharides results in increased activity of STAT3 protein CTD PMID:21586572 more ... lipopolysaccharide multiple interactions ISO RGD:69005 6480464 [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of STAT3 protein] more ... CTD PMID:16275627 more ... lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of STAT3 protein CTD PMID:12584205 lipopolysaccharide multiple interactions EXP 6480464 15-deoxy-delta(12 more ... CTD PMID:12584205 , PMID:35279615 lipopolysaccharide multiple interactions ISO RGD:737517 6480464 [Nicotine co-treated with Lipopolysaccharides] results in increased phosphorylation of STAT3 protein more ... CTD PMID:21135123 more ... lipoxin A4 multiple interactions ISO RGD:69005 6480464 lipoxin A4 inhibits the reaction [Ovalbumin results in increased phosphorylation of STAT3 protein] CTD PMID:34537180 lithium chloride multiple interactions ISO RGD:737517 6480464 Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein, N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 loganin multiple interactions ISO RGD:69005 6480464 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:35279615 loganin multiple interactions EXP 6480464 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein] CTD PMID:35279615 losartan decreases phosphorylation ISO RGD:69005 6480464 Losartan results in decreased phosphorylation of STAT3 protein CTD PMID:33380422 losartan decreases phosphorylation ISO RGD:737517 6480464 Losartan results in decreased phosphorylation of STAT3 protein CTD PMID:33380422 luteolin decreases phosphorylation ISO RGD:737517 6480464 Luteolin results in decreased phosphorylation of STAT3 protein CTD PMID:24525192 luteolin multiple interactions ISO RGD:737517 6480464 Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of STAT3 protein] more ... CTD PMID:24525192 , PMID:25448439 luteolin 7-O-beta-D-glucoside multiple interactions ISO RGD:737517 6480464 1 more ... CTD PMID:31381935 LY294002 multiple interactions ISO RGD:737517 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Silicon Dioxide results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:16427044 , PMID:29894800 LY294002 multiple interactions EXP 6480464 Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein] CTD PMID:34455488 LY294002 increases phosphorylation EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein CTD PMID:34455488 lycopene increases expression ISO RGD:737517 6480464 lycopene results in increased expression of STAT3 mRNA CTD PMID:16886892 lycorine multiple interactions ISO RGD:69005 6480464 lycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein] CTD PMID:22155741 malaoxon decreases phosphorylation EXP 6480464 malaoxon results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 malathion decreases phosphorylation EXP 6480464 Malathion results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 maneb multiple interactions ISO RGD:69005 6480464 [Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA more ... CTD PMID:23963992 manganese atom multiple interactions ISO RGD:69005 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein], [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein CTD PMID:34018660 manganese(0) multiple interactions ISO RGD:69005 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein], [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein CTD PMID:34018660 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of STAT3 mRNA CTD PMID:28801915 manganese(II) chloride multiple interactions ISO RGD:69005 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein], [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein CTD PMID:34018660 manganese(II) chloride decreases expression ISO RGD:69005 6480464 manganese chloride results in decreased expression of STAT3 mRNA CTD PMID:28801915 manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of STAT3 gene CTD PMID:28801915 manumycin A multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [manumycin results in decreased phosphorylation of STAT3 protein] CTD PMID:19409983 manumycin A decreases phosphorylation ISO RGD:737517 6480464 manumycin results in decreased phosphorylation of STAT3 protein CTD PMID:19409983 maslinic acid multiple interactions ISO RGD:69005 6480464 maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein], maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] CTD PMID:26513295 masoprocol decreases phosphorylation ISO RGD:737517 6480464 Masoprocol results in decreased phosphorylation of STAT3 protein CTD PMID:19503098 melatonin multiple interactions ISO RGD:69005 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA] more ... CTD PMID:22225513 more ... melatonin increases response to substance ISO RGD:69005 6480464 STAT3 protein results in increased susceptibility to Melatonin CTD PMID:21342247 melatonin increases phosphorylation ISO RGD:69005 6480464 Melatonin results in increased phosphorylation of STAT3 protein CTD PMID:21342247 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein] CTD PMID:19028472 melittin decreases phosphorylation ISO RGD:737517 6480464 Melitten results in decreased phosphorylation of STAT3 protein CTD PMID:22027265 melittin multiple interactions EXP 6480464 Melitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased expression of STAT3 mRNA], Melitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:21354845 melittin multiple interactions ISO RGD:737517 6480464 TNFRSF10A protein affects the reaction [Melitten results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:22027265 mercury dichloride multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:16896058 , PMID:19635391 mercury dichloride multiple interactions ISO RGD:69005 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride results in increased phosphorylation of STAT3 protein] CTD PMID:29981841 mercury dichloride increases phosphorylation ISO RGD:69005 6480464 Mercuric Chloride analog results in increased phosphorylation of STAT3 protein, Mercuric Chloride results in increased phosphorylation of STAT3 protein CTD PMID:29981841 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:35122774 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of STAT3 mRNA CTD PMID:30467583 methapyrilene increases methylation ISO RGD:737517 6480464 Methapyrilene results in increased methylation of STAT3 intron CTD PMID:30157460 methotrexate decreases expression ISO RGD:737517 6480464 Methotrexate results in decreased expression of STAT3 mRNA CTD PMID:24449571 methotrexate multiple interactions ISO RGD:737517 6480464 Methotrexate inhibits the reaction [Oncostatin M results in increased expression of STAT3 mRNA] CTD PMID:34953855 methoxychlor multiple interactions ISO RGD:737517 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 methyl methanesulfonate decreases expression ISO RGD:737517 6480464 Methyl Methanesulfonate results in decreased expression of STAT3 mRNA CTD PMID:23649840 methylarsonic acid multiple interactions ISO RGD:737517 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA CTD PMID:23192986 methylglyoxal increases phosphorylation EXP 6480464 Pyruvaldehyde results in increased phosphorylation of STAT3 protein CTD PMID:34455488 methylglyoxal multiple interactions EXP 6480464 Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of STAT3 protein] CTD PMID:34455488 methyllycaconitine multiple interactions ISO RGD:737517 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 methyllycaconitine multiple interactions EXP 6480464 methyllycaconitine inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form] CTD PMID:29501575 methyllycaconitine decreases phosphorylation ISO RGD:69005 6480464 methyllycaconitine results in decreased phosphorylation of STAT3 protein CTD PMID:25396421 methylmercury chloride increases expression ISO RGD:69005 6480464 methylmercuric chloride results in increased expression of STAT3 mRNA CTD PMID:33338554 methylmercury chloride multiple interactions ISO RGD:69005 6480464 methylmercuric chloride promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein] CTD PMID:33338554 Methylthiouracil multiple interactions ISO RGD:737517 6480464 Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein] CTD PMID:26298005 microcystin-LR increases phosphorylation ISO RGD:69005 6480464 cyanoginosin LR results in increased phosphorylation of STAT3 protein CTD PMID:33474710 monocrotaline multiple interactions EXP 6480464 [Monocrotaline co-treated with TGFB1] results in increased phosphorylation of STAT3 protein, NCP-2454 inhibits the reaction [Monocrotaline results in increased phosphorylation of STAT3 protein] CTD PMID:25275723 , PMID:27870162 monocrotaline increases phosphorylation EXP 6480464 Monocrotaline results in increased phosphorylation of STAT3 protein CTD PMID:25275723 monosodium L-glutamate multiple interactions ISO RGD:69005 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of STAT3 mRNA CTD PMID:23783067 monosodium L-glutamate decreases phosphorylation ISO RGD:69005 6480464 Sodium Glutamate results in decreased phosphorylation of STAT3 protein CTD PMID:24502529 morphine increases phosphorylation ISO RGD:69005 6480464 Morphine results in increased phosphorylation of STAT3 protein CTD PMID:18385270 Morroniside multiple interactions EXP 6480464 morroniside inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein] CTD PMID:35279615 Morroniside multiple interactions ISO RGD:69005 6480464 morroniside inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:35279615 morusin decreases phosphorylation ISO RGD:737517 6480464 morusin results in decreased phosphorylation of STAT3 protein CTD PMID:25476160 morusin multiple interactions ISO RGD:737517 6480464 morusin results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:25476160 myo-inositol hexakisphosphate multiple interactions ISO RGD:69005 6480464 Phytic Acid inhibits the reaction [Urethane results in increased expression of and results in increased phosphorylation of STAT3 protein], Phytic Acid inhibits the reaction [Urethane results in increased expression of STAT3 mRNA] CTD PMID:22797328 myricetin multiple interactions ISO RGD:69005 6480464 myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA], myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:18995957 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine decreases expression ISO RGD:737517 6480464 N more ... CTD PMID:18778698 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:737517 6480464 TP53 mutant form inhibits the reaction [N more ... CTD PMID:18778698 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:737517 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions EXP 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of STAT3 protein] CTD PMID:31231976 N-acetyl-L-cysteine treatment ISO RGD:737517 127284846 N-acetyl-L-cysteine co-treated with Il-6 inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of STAT3 protein in the stomach) RGD N-acetyl-L-cysteine decreases phosphorylation ISO RGD:737517 6480464 Acetylcysteine results in decreased phosphorylation of STAT3 protein CTD PMID:29894800 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein], Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]] CTD PMID:21912612 N-acetyl-L-cysteine multiple interactions ISO RGD:69005 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:16481037 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:16896058 more ... N-butyl-N-(4-hydroxybutyl)nitrosamine multiple interactions EXP 6480464 [Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form more ... CTD PMID:29501575 N-butyl-N-(4-hydroxybutyl)nitrosamine increases expression EXP 6480464 Butylhydroxybutylnitrosamine results in increased expression of STAT3 mRNA CTD PMID:35771629 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:69005 6480464 Ethylnitrosourea results in increased mutagenesis of STAT3 mRNA CTD PMID:27776689 N-ethyl-N-nitrosourea decreases phosphorylation ISO RGD:69005 6480464 Ethylnitrosourea results in decreased phosphorylation of STAT3 protein CTD PMID:27725143 N-methyl-4-phenylpyridinium decreases phosphorylation ISO RGD:737517 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein CTD PMID:31381935 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of STAT3 mRNA CTD PMID:28801915 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:737517 6480464 1 more ... CTD PMID:28958159 , PMID:31381935 N-methyl-4-phenylpyridinium increases expression ISO RGD:737517 6480464 1-Methyl-4-phenylpyridinium results in increased expression of STAT3 mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein CTD PMID:28958159 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein CTD PMID:26648565 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 RTN4 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein], Sirolimus inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein] CTD PMID:26648565 N-nitrosodiethylamine increases phosphorylation ISO RGD:69005 127285675 N-nitrosodiethylamine increases phosphorylation of Stat3 protein in liver RGD N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of STAT3 protein CTD PMID:29698782 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein, Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 N-phosphocreatine multiple interactions EXP 6480464 Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein] more ... CTD PMID:34455488 N-phosphocreatine increases response to substance EXP 6480464 STAT3 protein results in increased susceptibility to Phosphocreatine CTD PMID:34455488 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO RGD:737517 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:10616907 naringin affects expression ISO RGD:69005 6480464 naringin affects the expression of STAT3 mRNA, naringin affects the expression of STAT3 protein CTD PMID:25117567 nickel atom increases expression ISO RGD:737517 6480464 Nickel results in increased expression of STAT3 mRNA CTD PMID:24768652 , PMID:25583101 nickel atom multiple interactions ISO RGD:737517 6480464 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide more ... CTD PMID:35623502 niclosamide decreases expression ISO RGD:737517 6480464 Niclosamide analog results in decreased expression of STAT3 protein, Niclosamide results in decreased expression of STAT3 protein CTD PMID:26116531 , PMID:28284560 niclosamide multiple interactions ISO RGD:69005 6480464 Niclosamide affects the reaction [FAS protein mutant form affects the phosphorylation of STAT3 protein] CTD PMID:33632240 niclosamide decreases phosphorylation ISO RGD:737517 6480464 Niclosamide analog results in decreased phosphorylation of STAT3 protein, Niclosamide results in decreased phosphorylation of STAT3 protein CTD PMID:23333246 more ... niclosamide multiple interactions ISO RGD:737517 6480464 [Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]] which results in increased susceptibility to Erlotinib Hydrochloride more ... CTD PMID:23894143 more ... nicotine multiple interactions ISO RGD:737517 6480464 [alpha-cyano-(3 more ... CTD PMID:18448488 more ... nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:34153408 nicotine affects expression EXP 6480464 Nicotine affects the expression of STAT3 mRNA CTD PMID:29155039 nicotine multiple interactions EXP 6480464 [Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form more ... CTD PMID:29501575 , PMID:34153408 nicotine increases response to substance ISO RGD:737517 6480464 STAT3 results in increased susceptibility to Nicotine CTD PMID:20943775 nicotine increases activity ISO RGD:737517 6480464 Nicotine results in increased activity of STAT3 protein CTD PMID:18448488 nicotine increases phosphorylation ISO RGD:737517 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:18448488 , PMID:35131329 nicotine multiple interactions ISO RGD:69005 6480464 HMOX1 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein] more ... CTD PMID:24095726 nicotine increases response to substance ISO RGD:69005 6480464 STAT3 protein results in increased susceptibility to Nicotine CTD PMID:24095726 nicotine increases phosphorylation ISO RGD:69005 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:24095726 , PMID:25396421 nifuroxazide multiple interactions EXP 6480464 nifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein] CTD PMID:29291386 nimesulide decreases phosphorylation ISO RGD:737517 127285656 Nimesulide decreases phoshphorylation of STAT3 in esophagus squamous epithelium RGD nitrofen increases expression EXP 6480464 nitrofen results in increased expression of STAT3 protein modified form CTD PMID:25812446 nitrofurantoin multiple interactions ISO RGD:737517 6480464 Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein], Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]] CTD PMID:15748169 nitrofurantoin increases activity EXP 6480464 Nitrofurantoin results in increased activity of STAT3 protein CTD PMID:11841787 nitrofurantoin increases expression EXP 6480464 Nitrofurantoin results in increased expression of STAT3 mRNA CTD PMID:11841787 nitroglycerin increases expression EXP 6480464 Nitroglycerin results in increased expression of STAT3 mRNA CTD PMID:12102619 ochratoxin A multiple interactions ISO RGD:69005 6480464 [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA CTD PMID:28935500 olanzapine multiple interactions EXP 6480464 olanzapine promotes the reaction [[STAT3 protein binds to RGS7 promoter] which results in increased expression of RGS7 mRNA], olanzapine promotes the reaction [STAT3 protein binds to RGS7 promoter] CTD PMID:18976543 oleanolic acid increases expression ISO RGD:69005 6480464 Oleanolic Acid results in increased expression of STAT3 mRNA CTD PMID:18706400 oleanolic acid multiple interactions ISO RGD:69005 6480464 Oleanolic Acid inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:31306688 oleanolic acid multiple interactions ISO RGD:737517 6480464 [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of STAT3 mRNA CTD PMID:31401087 oridonin multiple interactions ISO RGD:69005 6480464 oridonin analog inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:31594861 oridonin multiple interactions ISO RGD:737517 6480464 oridonin analog binds to and results in decreased stability of STAT3 protein more ... CTD PMID:31594861 oridonin decreases phosphorylation ISO RGD:737517 6480464 oridonin analog results in decreased phosphorylation of STAT3 protein CTD PMID:31594861 osimertinib multiple interactions ISO RGD:737517 6480464 osimertinib affects the reaction [EGF protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:30623574 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of STAT3 mRNA CTD PMID:25729387 ozone increases phosphorylation ISO RGD:69005 6480464 Ozone results in increased phosphorylation of STAT3 protein CTD PMID:20826374 , PMID:26342085 ozone increases expression ISO RGD:69005 6480464 Ozone results in increased expression of STAT3 mRNA CTD PMID:26342085 p-tert-Amylphenol increases phosphorylation ISO RGD:737517 6480464 4-tert-octylphenol results in increased phosphorylation of STAT3 protein CTD PMID:32466334 paclitaxel multiple interactions ISO RGD:737517 6480464 Luteolin promotes the reaction [Paclitaxel results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:20106947 , PMID:24525192 paclitaxel decreases response to substance ISO RGD:737517 6480464 STAT3 protein results in decreased susceptibility to Paclitaxel CTD PMID:20106947 paclitaxel decreases phosphorylation ISO RGD:737517 6480464 Paclitaxel results in decreased phosphorylation of STAT3 protein CTD PMID:24525192 paclitaxel decreases activity ISO RGD:737517 6480464 Paclitaxel results in decreased activity of STAT3 protein CTD PMID:20106947 panobinostat multiple interactions ISO RGD:737517 6480464 Panobinostat inhibits the reaction [STAT3 protein binds to GADD45G promoter] more ... CTD PMID:23681230 paracetamol affects expression ISO RGD:69005 6480464 Acetaminophen affects the expression of STAT3 mRNA CTD PMID:17562736 paracetamol increases activity ISO RGD:69005 6480464 Acetaminophen results in increased activity of STAT3 protein CTD PMID:34726736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of STAT3 mRNA CTD PMID:33387578 paracetamol increases phosphorylation ISO RGD:69005 6480464 Acetaminophen results in increased phosphorylation of STAT3 protein CTD PMID:25265579 , PMID:32045647 paracetamol increases expression ISO RGD:737517 6480464 Acetaminophen results in increased expression of STAT3 mRNA CTD PMID:22230336 paracetamol multiple interactions ISO RGD:69005 6480464 MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of STAT3 mRNA], saikosaponin D inhibits the reaction [Acetaminophen results in increased phosphorylation of STAT3 protein] CTD PMID:18700144 , PMID:25265579 paracetamol increases expression ISO RGD:69005 6480464 Acetaminophen results in increased expression of STAT3 mRNA CTD PMID:11752693 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of STAT3 mRNA CTD PMID:17522070 paraoxon decreases phosphorylation EXP 6480464 Paraoxon results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 paraquat increases expression ISO RGD:69005 6480464 Paraquat results in increased expression of STAT3 mRNA alternative form CTD PMID:17215068 paraquat multiple interactions ISO RGD:69005 6480464 [Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA more ... CTD PMID:23963992 paroxetine decreases expression ISO RGD:737517 6480464 Paroxetine results in decreased expression of STAT3 mRNA, Paroxetine results in decreased expression of STAT3 protein CTD PMID:17499975 paroxetine multiple interactions ISO RGD:737517 6480464 LY 215840 promotes the reaction [Paroxetine results in increased expression of STAT3 mRNA] CTD PMID:32020710 paroxetine increases expression ISO RGD:737517 6480464 Paroxetine results in increased expression of STAT3 mRNA CTD PMID:32020710 pentachlorophenol multiple interactions ISO RGD:737517 6480464 HMGB1 protein promotes the reaction [Pentachlorophenol results in increased expression of STAT3 mRNA], HSPA1A protein promotes the reaction [Pentachlorophenol results in increased expression of STAT3 mRNA] CTD PMID:35550411 pentachlorophenol increases expression ISO RGD:737517 6480464 Pentachlorophenol results in increased expression of STAT3 mRNA, Pentachlorophenol results in increased expression of STAT3 protein CTD PMID:35550411 phenethyl caffeate multiple interactions ISO RGD:69005 6480464 caffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein] CTD PMID:22155090 phenethyl caffeate multiple interactions ISO RGD:737517 6480464 caffeic acid phenethyl ester analog affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32125059 phenformin increases expression EXP 6480464 Phenformin results in increased expression of STAT3 mRNA CTD PMID:31324951 phenobarbital affects expression ISO RGD:69005 6480464 Phenobarbital affects the expression of STAT3 mRNA CTD PMID:23091169 phenylarsine oxide multiple interactions ISO RGD:737517 6480464 Hydrogen Peroxide promotes the reaction [oxophenylarsine affects the localization of STAT3 protein] more ... CTD PMID:10364193 , PMID:11882386 phenylarsine oxide affects localization ISO RGD:737517 6480464 oxophenylarsine affects the localization of STAT3 protein CTD PMID:10364193 phenylarsine oxide multiple interactions ISO RGD:69005 6480464 oxophenylarsine inhibits the reaction [EGF protein affects the localization of and results in increased activity of STAT3 protein] CTD PMID:12093727 phenylephrine affects localization EXP 6480464 Phenylephrine affects the localization of STAT3 protein CTD PMID:19299911 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of STAT3 CTD PMID:19299911 phenylephrine multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] more ... CTD PMID:19299911 , PMID:27094369 phenylpropanolamine increases activity EXP 6480464 Phenylpropanolamine results in increased activity of STAT3 protein CTD PMID:24792324 phenylpropanolamine increases expression EXP 6480464 Phenylpropanolamine results in increased expression of STAT3 mRNA, Phenylpropanolamine results in increased expression of STAT3 protein modified form CTD PMID:24792324 phenylpropanolamine multiple interactions EXP 6480464 Enzyme Inhibitors inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 protein modified form] more ... CTD PMID:24792324 phenylpropanolamine increases response to substance EXP 6480464 STAT3 mRNA results in increased susceptibility to Phenylpropanolamine CTD PMID:24792324 PhIP multiple interactions ISO RGD:737517 6480464 fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of STAT3 mRNA] CTD PMID:29362861 PhIP increases expression ISO RGD:737517 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of STAT3 mRNA CTD PMID:29362861 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:737517 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein CTD PMID:20523355 , PMID:24496235 phorbol 13-acetate 12-myristate affects localization ISO RGD:737517 6480464 Tetradecanoylphorbol Acetate affects the localization of STAT3 protein CTD PMID:30133131 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:69005 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein CTD PMID:22986104 , PMID:26513295 phorbol 13-acetate 12-myristate increases expression ISO RGD:69005 6480464 Tetradecanoylphorbol Acetate results in increased expression of STAT3 CTD PMID:26100520 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:69005 6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]] more ... CTD PMID:22986104 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:737517 6480464 [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein, diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] CTD PMID:20523355 , PMID:25128825 phorone increases activity EXP 6480464 phorone results in increased activity of STAT3 protein CTD PMID:11841787 phorone increases expression EXP 6480464 phorone results in increased expression of STAT3 mRNA CTD PMID:11841787 phosphatidic acid multiple interactions ISO RGD:69005 6480464 Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT3 protein CTD PMID:16354768 physostigmine decreases phosphorylation ISO RGD:69005 6480464 Physostigmine results in decreased phosphorylation of STAT3 protein CTD PMID:28500787 piperine multiple interactions ISO RGD:69005 6480464 piperine inhibits the reaction [IL2 protein results in increased phosphorylation of STAT3 protein] CTD PMID:25655587 pipoxolan multiple interactions ISO RGD:69005 6480464 pipoxolan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein] CTD PMID:32677756 pirinixic acid decreases expression ISO RGD:69005 6480464 pirinixic acid results in decreased expression of STAT3 mRNA CTD PMID:17321000 pirinixic acid multiple interactions ISO RGD:69005 6480464 pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17321000 , PMID:27853831 pirinixic acid increases expression ISO RGD:69005 6480464 pirinixic acid results in increased expression of STAT3 mRNA CTD PMID:18445702 piroxicam multiple interactions ISO RGD:737517 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of STAT3 mRNA CTD PMID:21858171 platycodin D multiple interactions ISO RGD:69005 6480464 platycodin D inhibits the reaction [[IL6 protein co-treated with TGFB1 protein] results in increased phosphorylation of STAT3 protein] CTD PMID:25887267 poly(I:C) multiple interactions ISO RGD:69005 6480464 IL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein], Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein CTD PMID:21195166 Ponicidin decreases phosphorylation ISO RGD:737517 127285620 Ponicidin decreases phosphorylation of STAT3 protein in the stomach RGD potassium dichromate multiple interactions ISO RGD:737517 6480464 LCK protein affects the reaction [Potassium Dichromate results in increased phosphorylation of STAT3 protein alternative form], Potassium Dichromate results in increased phosphorylation of and results in increased activity of and affects the localization of STAT3 protein alternative form CTD PMID:17078813 pravastatin decreases phosphorylation ISO RGD:69005 6480464 Pravastatin results in decreased phosphorylation of STAT3 protein CTD PMID:19330073 progesterone multiple interactions ISO RGD:737517 6480464 Progesterone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:21768398 propiconazole decreases expression ISO RGD:69005 6480464 propiconazole results in decreased expression of STAT3 mRNA CTD PMID:21278054 propionic acid increases expression EXP 6480464 propionic acid results in increased expression of STAT3 protein CTD PMID:32481507 propofol decreases phosphorylation ISO RGD:737517 125097524 Propofol decreases phosphorylation of STAT3 protein in colon epithelium RGD propofol multiple interactions EXP 6480464 HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]] more ... CTD PMID:24810525 propofol increases phosphorylation EXP 6480464 Propofol results in increased phosphorylation of STAT3 protein CTD PMID:24810525 propranolol multiple interactions ISO RGD:737517 6480464 Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 , PMID:20106947 prostaglandin E2 multiple interactions ISO RGD:69005 6480464 Dinoprostone inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein], Dinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]] CTD PMID:21268125 , PMID:25432964 pterostilbene decreases expression ISO RGD:737517 6480464 pterostilbene results in decreased expression of STAT3 protein modified form CTD PMID:22450950 pterostilbene decreases phosphorylation ISO RGD:69005 6480464 pterostilbene results in decreased phosphorylation of STAT3 protein CTD PMID:26138072 pterostilbene decreases phosphorylation ISO RGD:737517 6480464 pterostilbene results in decreased phosphorylation of STAT3 protein CTD PMID:26138072 pterostilbene decreases activity ISO RGD:737517 6480464 pterostilbene results in decreased activity of STAT3 protein CTD PMID:23313376 Punicalagin affects localization ISO RGD:737517 6480464 punicalagin affects the localization of STAT3 protein CTD PMID:33720461 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA] CTD PMID:11578593 quercetin decreases phosphorylation ISO RGD:69005 6480464 Quercetin results in decreased phosphorylation of STAT3 protein CTD PMID:24275163 quercetin increases phosphorylation ISO RGD:737517 6480464 Quercetin results in increased phosphorylation of STAT3 protein CTD PMID:22230496 quercetin multiple interactions ISO RGD:737517 6480464 [Docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:20153296 more ... quercetin decreases phosphorylation ISO RGD:737517 6480464 Quercetin results in decreased phosphorylation of STAT3 protein CTD PMID:24275163 , PMID:27468969 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of STAT3 protein], Quercetin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein] CTD PMID:22426011 , PMID:23533474 quercetin decreases expression ISO RGD:69005 6480464 Quercetin results in decreased expression of STAT3 mRNA CTD PMID:24275163 quercetin 3-O-beta-D-glucofuranoside increases expression ISO RGD:737517 6480464 isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 quercetin 3-O-beta-D-glucopyranoside increases expression ISO RGD:737517 6480464 isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 raloxifene multiple interactions ISO RGD:737517 6480464 [Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17336289 reactive oxygen species multiple interactions ISO RGD:69005 6480464 [[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein] more ... CTD PMID:23376140 reparixin multiple interactions ISO RGD:737517 6480464 reparixin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of STAT3 protein] CTD PMID:33396024 resiquimod increases expression ISO RGD:69005 6480464 resiquimod results in increased expression of STAT3 mRNA CTD PMID:17238832 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA], Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein] CTD PMID:23421680 resveratrol increases phosphorylation ISO RGD:737517 6480464 resveratrol results in increased phosphorylation of STAT3 protein CTD PMID:22748497 resveratrol decreases expression ISO RGD:737517 6480464 resveratrol results in decreased expression of STAT3 more ... CTD PMID:18592012 more ... resveratrol decreases activity ISO RGD:737517 6480464 resveratrol results in decreased activity of STAT3 protein CTD PMID:21503893 , PMID:25061499 resveratrol affects activity ISO RGD:737517 6480464 resveratrol affects the activity of STAT3 protein CTD PMID:25063218 resveratrol affects localization ISO RGD:737517 6480464 resveratrol affects the localization of STAT3 protein CTD PMID:18592012 more ... resveratrol decreases phosphorylation ISO RGD:737517 6480464 resveratrol results in decreased phosphorylation of STAT3 protein CTD PMID:18592012 more ... resveratrol increases expression ISO RGD:69005 6480464 resveratrol results in increased expression of STAT3 protein CTD PMID:25505154 resveratrol decreases phosphorylation ISO RGD:69005 6480464 resveratrol results in decreased phosphorylation of STAT3 protein CTD PMID:26138072 resveratrol increases phosphorylation ISO RGD:69005 6480464 resveratrol results in increased phosphorylation of STAT3 protein CTD PMID:21342247 resveratrol increases response to substance ISO RGD:69005 6480464 STAT3 protein results in increased susceptibility to resveratrol CTD PMID:21342247 resveratrol decreases acetylation ISO RGD:737517 6480464 resveratrol results in decreased acetylation of STAT3 protein CTD PMID:23681230 resveratrol decreases expression ISO RGD:69005 6480464 resveratrol results in decreased expression of STAT3 protein modified form CTD PMID:19063842 resveratrol multiple interactions ISO RGD:69005 6480464 IL10 protein affects the reaction [Resveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:19796711 more ... resveratrol multiple interactions ISO RGD:737517 6480464 6-chloro-2 more ... CTD PMID:16546976 more ... Rhynchophylline multiple interactions EXP 6480464 rhyncophylline inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of STAT3 protein] CTD PMID:31231976 rimonabant multiple interactions ISO RGD:69005 6480464 Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein] CTD PMID:16046413 risperidone multiple interactions EXP 6480464 Risperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA] CTD PMID:17442543 ritodrine increases phosphorylation ISO RGD:69005 6480464 Ritodrine results in increased phosphorylation of STAT3 protein CTD PMID:23370008 ritonavir decreases phosphorylation ISO RGD:737517 6480464 Ritonavir results in decreased phosphorylation of STAT3 protein CTD PMID:21270666 rofecoxib increases expression ISO RGD:737517 6480464 rofecoxib results in increased expression of STAT3 mRNA CTD PMID:17070997 rotenone multiple interactions ISO RGD:737517 6480464 Rotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:15748169 , PMID:19635391 rotenone decreases expression ISO RGD:737517 6480464 Rotenone results in decreased expression of STAT3 mRNA, Rotenone results in decreased expression of STAT3 protein CTD PMID:31408661 rotenone increases expression EXP 6480464 Rotenone results in increased expression of STAT3 mRNA CTD PMID:28374803 rotenone affects response to substance ISO RGD:69005 6480464 STAT3 protein affects the susceptibility to Rotenone CTD PMID:20224768 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of STAT3 mRNA CTD PMID:17442543 rotenone multiple interactions EXP 6480464 Risperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA] CTD PMID:17442543 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA], Rutin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein] CTD PMID:22426011 , PMID:26062544 ruxolitinib multiple interactions ISO RGD:737517 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of STAT3 protein, ruxolitinib inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein] CTD PMID:24820114 , PMID:30012499 S-butyl-DL-homocysteine (S,R)-sulfoximine increases activity EXP 6480464 Buthionine Sulfoximine results in increased activity of STAT3 protein CTD PMID:11841787 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression EXP 6480464 Buthionine Sulfoximine results in increased expression of STAT3 mRNA CTD PMID:11841787 Salinomycin multiple interactions ISO RGD:737517 6480464 salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:32822738 sarpogrelate multiple interactions ISO RGD:737517 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein], sarpogrelate inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 sarpogrelate multiple interactions ISO RGD:69005 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein], sarpogrelate inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 SB 203580 multiple interactions ISO RGD:737517 6480464 SB 203580 inhibits the reaction [1 more ... CTD PMID:30871965 , PMID:33030807 SB 203580 increases phosphorylation ISO RGD:737517 6480464 SB 203580 results in increased phosphorylation of STAT3 protein CTD PMID:33030807 Se-methyl-L-selenocysteine multiple interactions ISO RGD:737517 6480464 selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter], STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 Se-methylselenocysteine multiple interactions ISO RGD:737517 6480464 selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter], STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 selenic acid increases activity ISO RGD:737517 6480464 Selenic Acid results in increased activity of STAT3 protein CTD PMID:22366233 sertraline decreases expression ISO RGD:737517 6480464 Sertraline results in decreased expression of STAT3 mRNA, Sertraline results in decreased expression of STAT3 protein CTD PMID:17499975 silicon dioxide multiple interactions ISO RGD:69005 6480464 [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA more ... CTD PMID:20490462 more ... silicon dioxide increases phosphorylation ISO RGD:69005 6480464 Silicon Dioxide results in increased phosphorylation of STAT3 protein CTD PMID:30658076 silicon dioxide multiple interactions ISO RGD:737517 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Silicon Dioxide results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:29894800 silicon dioxide increases expression ISO RGD:69005 6480464 Silicon Dioxide results in increased expression of STAT3 mRNA CTD PMID:20490462 , PMID:23221170 simvastatin decreases activity ISO RGD:737517 6480464 Simvastatin results in decreased activity of STAT3 protein CTD PMID:19886038 simvastatin decreases phosphorylation ISO RGD:737517 6480464 Simvastatin results in decreased phosphorylation of STAT3 protein CTD PMID:18453621 , PMID:21910007 simvastatin decreases phosphorylation EXP 6480464 Simvastatin results in decreased phosphorylation of STAT3 protein CTD PMID:18400235 simvastatin decreases activity ISO RGD:69005 6480464 Simvastatin results in decreased activity of STAT3 protein CTD PMID:19886038 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]] more ... CTD PMID:16534557 more ... simvastatin affects expression ISO RGD:69005 6480464 Simvastatin affects the expression of STAT3 protein CTD PMID:17507688 simvastatin multiple interactions ISO RGD:737517 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein] CTD PMID:18453621 sirolimus decreases phosphorylation ISO RGD:737517 6480464 Sirolimus results in decreased phosphorylation of STAT3 protein CTD PMID:20038814 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein] CTD PMID:26648565 sirolimus decreases phosphorylation EXP 6480464 Sirolimus results in decreased phosphorylation of STAT3 protein CTD PMID:16391472 sirolimus multiple interactions ISO RGD:737517 6480464 Sirolimus inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein] CTD PMID:16427044 sodium arsenate decreases expression ISO RGD:69005 6480464 sodium arsenate results in decreased expression of STAT3 mRNA CTD PMID:30953684 sodium arsenite multiple interactions ISO RGD:737517 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA more ... CTD PMID:15116095 more ... sodium arsenite increases phosphorylation ISO RGD:737517 6480464 sodium arsenite results in increased phosphorylation of STAT3 protein CTD PMID:26101800 more ... sodium arsenite decreases phosphorylation ISO RGD:737517 6480464 sodium arsenite results in decreased phosphorylation of STAT3 protein CTD PMID:29039521 sodium arsenite increases expression ISO RGD:737517 6480464 sodium arsenite results in increased expression of STAT3 mRNA CTD PMID:28444938 sodium arsenite decreases expression ISO RGD:69005 6480464 sodium arsenite results in decreased expression of STAT3 mRNA, sodium arsenite results in decreased expression of STAT3 protein modified form CTD PMID:23143138 , PMID:28370166 sodium arsenite increases phosphorylation ISO RGD:69005 6480464 sodium arsenite results in increased phosphorylation of STAT3 protein CTD PMID:20008137 , PMID:26631322 sodium arsenite decreases response to substance ISO RGD:69005 6480464 STAT3 protein results in decreased susceptibility to sodium arsenite CTD PMID:23143138 sodium arsenite multiple interactions ISO RGD:69005 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein] more ... CTD PMID:20008137 more ... sodium arsenite decreases expression ISO RGD:737517 6480464 sodium arsenite results in decreased expression of STAT3 CTD PMID:17224793 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of STAT3 mRNA CTD PMID:25993096 Soman increases expression EXP 6480464 Soman results in increased expression of STAT3 mRNA CTD PMID:19281266 sorafenib decreases phosphorylation ISO RGD:737517 6480464 sorafenib analog results in decreased phosphorylation of STAT3 protein, sorafenib results in decreased phosphorylation of STAT3 protein CTD PMID:19001435 more ... sorafenib multiple interactions ISO RGD:737517 6480464 resveratrol promotes the reaction [sorafenib results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:18512153 more ... sorafenib affects localization ISO RGD:69005 6480464 sorafenib affects the localization of STAT3 protein CTD PMID:21360571 sphingosine 1-phosphate multiple interactions ISO RGD:737517 6480464 Janus Kinase Inhibitors inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of STAT3 protein] more ... CTD PMID:32401414 sphingosine 1-phosphate increases phosphorylation ISO RGD:737517 6480464 sphingosine 1-phosphate results in increased phosphorylation of STAT3 protein CTD PMID:32401414 stattic multiple interactions ISO RGD:737517 127284846 Stattic inhibits the reaction [Il-6 increases phosphorylation of STAT3 protein in the stomach) RGD stattic multiple interactions EXP 6480464 stattic inhibits the reaction [zoniporide results in increased phosphorylation of STAT3 protein] CTD PMID:20942815 stattic multiple interactions ISO RGD:69005 6480464 stattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:22454431 more ... stattic decreases phosphorylation ISO RGD:737517 6480464 stattic results in decreased phosphorylation of STAT3 protein CTD PMID:24627483 stattic multiple interactions ISO RGD:737517 6480464 stattic affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein] more ... CTD PMID:23255093 more ... staurosporine multiple interactions ISO RGD:737517 6480464 Staurosporine inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 stavudine decreases expression EXP 6480464 Stavudine results in decreased expression of STAT3 mRNA CTD PMID:18299183 stilbenoid affects activity ISO RGD:737517 6480464 Stilbenes analog affects the activity of STAT3 protein CTD PMID:25063218 streptozocin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:19958114 more ... streptozocin decreases phosphorylation EXP 6480464 Streptozocin results in decreased phosphorylation of STAT3 protein CTD PMID:21912612 , PMID:24810525 streptozocin increases phosphorylation EXP 6480464 Streptozocin results in increased phosphorylation of STAT3 protein CTD PMID:20821229 more ... streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of STAT3 mRNA, Streptozocin results in increased expression of STAT3 protein CTD PMID:19958114 SU6656 multiple interactions ISO RGD:69005 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:23376140 succinic acid multiple interactions ISO RGD:737517 6480464 [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of STAT3 mRNA CTD PMID:31401087 sulfasalazine multiple interactions ISO RGD:69005 6480464 Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein] CTD PMID:32272095 sulforaphane decreases expression ISO RGD:737517 6480464 sulforaphane results in decreased expression of STAT3 mRNA CTD PMID:31838189 sulindac multiple interactions ISO RGD:737517 6480464 BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form], BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein] CTD PMID:17401459 sulindac decreases expression ISO RGD:737517 6480464 Sulindac results in decreased expression of STAT3 protein, Sulindac results in decreased expression of STAT3 protein modified form CTD PMID:17401459 sulindac decreases phosphorylation ISO RGD:737517 6480464 Sulindac results in decreased phosphorylation of STAT3 protein CTD PMID:11861373 sulindac sulfide multiple interactions ISO RGD:737517 6480464 sulindac sulfide results in decreased expression of and results in decreased phosphorylation of STAT3 protein CTD PMID:17566705 sulindac sulfide decreases expression ISO RGD:737517 6480464 sulindac sulfide results in decreased expression of STAT3 mRNA CTD PMID:17566705 sunitinib decreases expression ISO RGD:737517 6480464 Sunitinib results in decreased expression of STAT3 mRNA CTD PMID:31533062 syringic acid decreases expression ISO RGD:737517 6480464 syringic acid results in decreased expression of STAT3 mRNA CTD PMID:33759321 T-2 toxin multiple interactions ISO RGD:69005 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of STAT3 mRNA CTD PMID:26141394 T-2 toxin increases expression ISO RGD:69005 6480464 T-2 Toxin results in increased expression of STAT3 mRNA CTD PMID:22454431 T-2 toxin increases phosphorylation ISO RGD:69005 6480464 T-2 Toxin results in increased phosphorylation of STAT3 protein CTD PMID:22454431 tacrolimus hydrate increases phosphorylation ISO RGD:69005 6480464 Tacrolimus results in increased phosphorylation of STAT3 protein CTD PMID:23958496 tamoxifen multiple interactions ISO RGD:737517 6480464 Tamoxifen inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of STAT3 protein modified form CTD PMID:17901229 tamoxifen multiple interactions ISO RGD:69005 6480464 Tamoxifen inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:16860915 Tanshinone I multiple interactions ISO RGD:737517 6480464 tanshinone inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein] CTD PMID:35304817 taurine decreases expression ISO RGD:737517 6480464 Taurine results in decreased expression of STAT3 mRNA CTD PMID:16579726 taurocholic acid multiple interactions ISO RGD:737517 6480464 sorafenib inhibits the reaction [Taurocholic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:18512153 taurocholic acid increases phosphorylation ISO RGD:737517 6480464 Taurocholic Acid results in increased phosphorylation of STAT3 protein CTD PMID:18512153 tert-butyl hydroperoxide multiple interactions ISO RGD:737517 6480464 3, 4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein] CTD PMID:29128606 tert-butyl hydroperoxide decreases phosphorylation ISO RGD:737517 6480464 tert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein CTD PMID:29128606 testosterone multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of STAT3 protein modified form] CTD PMID:32628957 testosterone increases expression ISO RGD:69005 6480464 Testosterone deficiency results in increased expression of STAT3 mRNA CTD PMID:33848595 testosterone increases expression EXP 6480464 Testosterone results in increased expression of STAT3 protein modified form CTD PMID:32628957 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of STAT3 mRNA CTD PMID:17522070 , PMID:26062544 tetrachloromethane increases phosphorylation ISO RGD:69005 6480464 Carbon Tetrachloride results in increased phosphorylation of STAT3 protein CTD PMID:14999682 more ... tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of STAT3 protein CTD PMID:17009398 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of STAT3 mRNA CTD PMID:16239168 tetrachloromethane multiple interactions ISO RGD:69005 6480464 2 more ... CTD PMID:12730884 more ... tetrachloromethane increases activity ISO RGD:69005 6480464 Carbon Tetrachloride results in increased activity of STAT3 protein CTD PMID:12730884 , PMID:12830005 tetrachloromethane multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA] CTD PMID:26062544 tetracycline increases expression EXP 6480464 Tetracycline results in increased expression of STAT3 mRNA CTD PMID:17522070 thalidomide decreases phosphorylation ISO RGD:737517 6480464 Thalidomide analog results in decreased phosphorylation of STAT3 protein CTD PMID:15858615 thalidomide multiple interactions ISO RGD:737517 6480464 [resveratrol co-treated with Thalidomide] results in decreased phosphorylation of STAT3 protein, Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein] CTD PMID:17164350 , PMID:17505005 thapsigargin multiple interactions EXP 6480464 Thapsigargin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:19285962 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of STAT3 protein CTD PMID:35544339 thapsigargin increases expression ISO RGD:69005 6480464 Thapsigargin results in increased expression of STAT3 protein CTD PMID:24648495 theobromine multiple interactions EXP 127229954 [Theobromine co-treated with Theanine] inhibits the reaction [1 more ... RGD theophylline increases expression ISO RGD:737517 6480464 Theophylline results in increased expression of STAT3 mRNA CTD PMID:16083514 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of STAT3 mRNA CTD PMID:34492290 thymoquinone multiple interactions ISO RGD:737517 6480464 Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of and results in decreased activity of STAT3 protein] more ... CTD PMID:31433961 , PMID:34627931 thymoquinone multiple interactions ISO RGD:69005 6480464 Doxorubicin promotes the reaction [thymoquinone results in decreased phosphorylation of STAT3 protein], thymoquinone inhibits the reaction [Doxorubicin results in increased phosphorylation of STAT3 protein] CTD PMID:34605108 thymoquinone decreases phosphorylation ISO RGD:737517 6480464 thymoquinone results in decreased phosphorylation of STAT3 protein CTD PMID:34627931 thymoquinone decreases phosphorylation ISO RGD:69005 6480464 thymoquinone results in decreased phosphorylation of STAT3 protein CTD PMID:34605108 thyroxine increases phosphorylation ISO RGD:737517 6480464 Thyroxine results in increased phosphorylation of STAT3 protein CTD PMID:31336132 thyroxine multiple interactions ISO RGD:737517 6480464 NSC 74859 inhibits the reaction [Thyroxine results in increased phosphorylation of STAT3 protein] CTD PMID:31336132 tofacitinib decreases activity ISO RGD:737517 6480464 tofacitinib results in decreased activity of STAT3 protein CTD PMID:22348037 tofacitinib multiple interactions ISO RGD:737517 6480464 tofacitinib inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21383241 more ... tofacitinib multiple interactions ISO RGD:69005 6480464 tofacitinib inhibits the reaction [IL1B protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21383241 more ... tofacitinib decreases phosphorylation ISO RGD:737517 6480464 tofacitinib results in decreased phosphorylation of STAT3 protein CTD PMID:25487280 , PMID:26244872 tofacitinib decreases expression ISO RGD:737517 6480464 tofacitinib results in decreased expression of STAT3 protein modified form CTD PMID:25398374 , PMID:27059729 tolcapone increases expression EXP 6480464 tolcapone results in increased expression of STAT3 mRNA CTD PMID:24136188 toluene increases expression ISO RGD:69005 6480464 Toluene results in increased expression of STAT3 mRNA CTD PMID:21601613 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of STAT3 mRNA CTD PMID:25729387 torcetrapib increases phosphorylation ISO RGD:737517 6480464 torcetrapib results in increased phosphorylation of STAT3 protein CTD PMID:25617244 trametinib multiple interactions ISO RGD:737517 6480464 physapubescin B inhibits the reaction [trametinib results in increased phosphorylation of STAT3 protein] CTD PMID:33035574 trametinib increases phosphorylation ISO RGD:737517 6480464 trametinib results in increased phosphorylation of STAT3 protein CTD PMID:33035574 trimethyltin increases expression ISO RGD:69005 6480464 trimethyltin results in increased expression of STAT3 mRNA, trimethyltin results in increased expression of STAT3 protein CTD PMID:21435392 Triptolide increases expression ISO RGD:69005 6480464 triptolide results in increased expression of STAT3 mRNA CTD PMID:24949944 trovafloxacin multiple interactions ISO RGD:69005 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of STAT3 mRNA CTD PMID:18930950 tungsten decreases expression ISO RGD:69005 6480464 Tungsten results in decreased expression of STAT3 mRNA CTD PMID:30912803 tyrphostin AG 1478 multiple interactions ISO RGD:737517 6480464 RTKI cpd inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA], RTKI cpd inhibits the reaction [EGF protein results in increased activity of STAT3 protein] CTD PMID:21909620 , PMID:25841994 tyrphostin AG 1478 decreases expression ISO RGD:737517 6480464 RTKI cpd results in decreased expression of STAT3 protein modified form CTD PMID:29974605 tyrphostin AG 1478 multiple interactions ISO RGD:69005 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein], [RTKI cpd results in decreased activity of EGFR protein] which results in decreased phosphorylation of STAT3 protein CTD PMID:21268125 , PMID:23376140 tyrphostin B42 multiple interactions ISO RGD:737517 127284886 tyrphostin B42 co-treated with N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases phosphorylation of STAT3 protein in stomach] RGD U50488 multiple interactions ISO RGD:69005 6480464 [3 more ... CTD PMID:18385270 urethane decreases expression ISO RGD:69005 6480464 Urethane results in decreased expression of STAT3 mRNA CTD PMID:12400877 urethane increases expression ISO RGD:737517 6480464 Urethane results in increased expression of STAT3 mRNA CTD PMID:28818685 urethane increases expression ISO RGD:69005 6480464 Urethane results in increased expression of STAT3 mRNA CTD PMID:22797328 urethane multiple interactions ISO RGD:69005 6480464 Phytic Acid inhibits the reaction [Urethane results in increased expression of and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:22797328 ursolic acid multiple interactions ISO RGD:69005 6480464 Resveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]] more ... CTD PMID:26100520 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of STAT3 mRNA CTD PMID:24136188 valproic acid increases expression ISO RGD:69005 6480464 Valproic Acid results in increased expression of STAT3 mRNA CTD PMID:21427059 valproic acid increases expression ISO RGD:737517 6480464 Valproic Acid results in increased expression of STAT3 mRNA CTD PMID:19101580 more ... valproic acid affects expression ISO RGD:737517 6480464 Valproic Acid affects the expression of STAT3 mRNA CTD PMID:25979313 valsartan multiple interactions ISO RGD:737517 6480464 Valsartan inhibits the reaction [AGT protein affects the localization of STAT3 protein] more ... CTD PMID:12846741 vanadium atom multiple interactions EXP 6480464 Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein] CTD PMID:16195403 vanadium(0) multiple interactions EXP 6480464 Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein] CTD PMID:16195403 vanadyl sulfate increases expression ISO RGD:737517 6480464 vanadyl sulfate results in increased expression of STAT3 mRNA CTD PMID:16330358 vancomycin decreases expression ISO RGD:69005 6480464 Vancomycin results in decreased expression of STAT3 mRNA CTD PMID:18930951 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein], Verapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 verteporfin multiple interactions ISO RGD:69005 6480464 Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:31812773 verteporfin decreases expression ISO RGD:69005 6480464 Verteporfin results in decreased expression of STAT3 protein CTD PMID:31812773 vincaleukoblastine multiple interactions ISO RGD:737517 6480464 Vinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 withaferin A multiple interactions ISO RGD:69005 6480464 withaferin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:21396905 wogonin decreases phosphorylation ISO RGD:737517 6480464 wogonin results in decreased phosphorylation of STAT3 protein CTD PMID:32671444 zinc atom decreases activity EXP 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc atom decreases phosphorylation ISO RGD:737517 6480464 Zinc deficiency results in decreased phosphorylation of STAT3 protein CTD PMID:28086195 zinc atom multiple interactions EXP 6480464 Zinc deficiency results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:28086195 zinc atom increases expression ISO RGD:69005 6480464 Zinc deficiency results in increased expression of STAT3 mRNA, Zinc results in increased expression of STAT3 mRNA CTD PMID:31505237 zinc atom multiple interactions ISO RGD:737517 6480464 Thioctic Acid inhibits the reaction [Zinc deficiency affects the localization of STAT3 protein] CTD PMID:28086195 zinc atom decreases activity ISO RGD:737517 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc protoporphyrin multiple interactions ISO RGD:69005 6480464 zinc protoporphyrin inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:24095726 zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]], zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]] CTD PMID:24810525 zinc sulfate multiple interactions ISO RGD:737517 6480464 Zinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:16896058 zinc(0) multiple interactions ISO RGD:737517 6480464 Thioctic Acid inhibits the reaction [Zinc deficiency affects the localization of STAT3 protein] CTD PMID:28086195 zinc(0) increases expression ISO RGD:69005 6480464 Zinc deficiency results in increased expression of STAT3 mRNA, Zinc results in increased expression of STAT3 mRNA CTD PMID:31505237 zinc(0) decreases activity EXP 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc(0) decreases activity ISO RGD:737517 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc(0) decreases phosphorylation ISO RGD:737517 6480464 Zinc deficiency results in decreased phosphorylation of STAT3 protein CTD PMID:28086195 zinc(0) multiple interactions EXP 6480464 Zinc deficiency results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:28086195 zoledronic acid increases expression ISO RGD:737517 6480464 zoledronic acid results in increased expression of STAT3 mRNA CTD PMID:24714768