GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | increases phosphorylation | EXP | | 6480464 | CTD | Capsaicin results in increased phosphorylation of STAT3 protein | PMID:16788306 | Stat3 | multiple interactions | EXP | | 6480464 | CTD | Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein] | PMID:16788306 PMID:19285962 | Stat3 | affects localization | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | Capsaicin affects the localization of STAT3 protein | PMID:17505005 | Stat3 | multiple interactions | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | Bortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein; pervanadate inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein] | PMID:17505005 | |
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