Stat3 (signal transducer and activator of transcription 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Stat3 (signal transducer and activator of transcription 3) Chinchilla lanigera
Analyze
Symbol: Stat3
Name: signal transducer and activator of transcription 3
RGD ID: 9047623
Description: ENCODES a protein that exhibits CCR5 chemokine receptor binding (ortholog); chromatin DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN acute-phase response (ortholog); astrocyte differentiation (ortholog); cell differentiation (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; Interleukin-10 signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); adenocarcinoma (ortholog); adenoid cystic carcinoma (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: signal transducer and activator of transcription 3 (acute-phase response factor)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,319,904 - 16,357,687 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,320,326 - 16,348,505 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoid cystic carcinoma  (ISO)
adult T-cell leukemia/lymphoma  (ISO)
Alzheimer's disease  (ISO)
anaplastic large cell lymphoma  (ISO)
angiomyolipoma  (ISO)
angiosarcoma  (ISO)
Animal Disease Models  (ISO)
Animal Mammary Neoplasms  (ISO)
atherosclerosis  (ISO)
Atrophy  (ISO)
autistic disorder  (ISO)
autoimmune disease  (ISO)
B-lymphoblastic leukemia/lymphoma  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
cervix uteri carcinoma in situ  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis  (ISO)
Chronic Hepatitis C  (ISO)
chronic lymphocytic leukemia  (ISO)
Churg-Strauss syndrome  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
colorectal carcinoma  (ISO)
congenital diaphragmatic hernia  (ISO)
congestive heart failure  (ISO)
Copper-Overload Cirrhosis  (ISO)
Crohn's disease  (ISO)
depressive disorder  (ISO)
Diabetic Nephropathies  (ISO)
diffuse large B-cell lymphoma  (ISO)
duodenal ulcer  (ISO)
Endometrial Neoplasms  (ISO)
Epidermal Hyperplasia  (ISO)
esophageal carcinoma  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Uveitis  (ISO)
Experimental Autoimmune Uveoretinitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Fever  (ISO)
Fibrosis  (ISO)
follicular dendritic cell sarcoma  (ISO)
gastric adenocarcinoma  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
growth hormone insensitivity syndrome with immune dysregulation 1  (ISO)
head and neck squamous cell carcinoma  (ISO)
heart disease  (ISO)
hepatocellular carcinoma  (ISO)
hyper IgE recurrent infection syndrome 1  (ISO)
hyper IgE syndrome  (ISO)
Hyperalgesia  (ISO)
hyperuricemia  (ISO)
idiopathic pulmonary fibrosis  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
irritant dermatitis  (ISO)
juvenile rheumatoid arthritis  (ISO)
liver cirrhosis  (ISO)
Liver Injury  (ISO)
Liver Neoplasms  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lymphangioleiomyomatosis  (ISO)
Lymphatic Metastasis  (ISO)
lymphoproliferative syndrome  (ISO)
medulloblastoma  (ISO)
Memory Disorders  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
middle cerebral artery infarction  (ISO)
Multisystem Autoimmune Disease, Infantile-Onset, 1  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
nasal type extranodal NK/T-cell lymphoma  (ISO)
nasopharynx carcinoma  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephroblastoma  (ISO)
neutropenia  (ISO)
Niemann-Pick disease type C1  (ISO)
obesity  (ISO)
ovarian cancer  (ISO)
Ovarian Neoplasms  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatic cancer  (ISO)
periodontitis  (ISO)
peripartum cardiomyopathy  (ISO)
pre-malignant neoplasm  (ISO)
primary immunodeficiency disease  (ISO)
prostate cancer  (ISO)
prostate carcinoma  (ISO)
Prostatic Neoplasms  (ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary fibrosis  (ISO)
Pyogenic Granuloma  (ISO)
rectum adenocarcinoma  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Retina Reperfusion Injury  (ISO)
rheumatoid arthritis  (ISO)
scrapie  (ISO)
Sepsis  (ISO)
Sepsis-Associated Encephalopathy  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
Subarachnoid Hemorrhage  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
T-cell non-Hodgkin lymphoma  (ISO)
Tongue Neoplasms  (ISO)
transient cerebral ischemia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (ISO)
astrocyte differentiation  (ISO)
cell differentiation  (ISO)
cell population proliferation  (ISO)
cell surface receptor signaling pathway via JAK-STAT  (ISO)
cell surface receptor signaling pathway via STAT  (ISO)
cellular response to cytokine stimulus  (ISO)
cellular response to hormone stimulus  (ISO)
cellular response to interleukin-17  (ISO)
cellular response to leptin stimulus  (ISO)
cellular response to organic cyclic compound  (ISO)
eating behavior  (ISO)
energy homeostasis  (ISO)
gene expression  (ISO)
glucose homeostasis  (ISO)
growth hormone receptor signaling pathway  (ISO)
growth hormone receptor signaling pathway via JAK-STAT  (ISO)
inflammatory response  (ISO)
interleukin-10-mediated signaling pathway  (ISO)
interleukin-11-mediated signaling pathway  (ISO)
interleukin-15-mediated signaling pathway  (ISO)
interleukin-2-mediated signaling pathway  (ISO)
interleukin-23-mediated signaling pathway  (ISO)
interleukin-6-mediated signaling pathway  (ISO)
interleukin-9-mediated signaling pathway  (ISO)
intracellular receptor signaling pathway  (ISO)
leptin-mediated signaling pathway  (ISO)
modulation of chemical synaptic transmission  (ISO)
mRNA transcription by RNA polymerase II  (ISO)
negative regulation of autophagy  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cellular process  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of glycolytic process  (ISO)
negative regulation of hydrogen peroxide biosynthetic process  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of inflammatory response to wounding  (ISO)
negative regulation of neuron migration  (ISO)
negative regulation of primary miRNA processing  (ISO)
negative regulation of stem cell differentiation  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
phosphorylation  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of ATP biosynthetic process  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cytokine production involved in inflammatory response  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of erythrocyte differentiation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation  (ISO)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of metalloendopeptidase activity  (ISO)
positive regulation of miRNA transcription  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of vascular endothelial cell proliferation  (ISO)
positive regulation of vascular endothelial growth factor production  (ISO)
postsynapse to nucleus signaling pathway  (ISO)
protein import into nucleus  (ISO)
radial glial cell differentiation  (ISO)
regulation of cell cycle  (ISO)
regulation of cellular response to hypoxia  (ISO)
regulation of DNA-templated transcription  (ISO)
regulation of feeding behavior  (ISO)
regulation of mitochondrial membrane permeability  (ISO)
regulation of multicellular organism growth  (ISO)
response to cytokine  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to ischemia  (ISO)
response to leptin  (ISO)
response to organic cyclic compound  (ISO)
response to peptide hormone  (ISO)
response to xenobiotic stimulus  (ISO)
retinal rod cell differentiation  (ISO)
sexual reproduction  (ISO)
somatic stem cell population maintenance  (ISO)
T-helper 17 cell lineage commitment  (ISO)
T-helper 17 type immune response  (ISO)
temperature homeostasis  (ISO)
transcription by RNA polymerase II  (ISO)
transforming growth factor beta receptor signaling pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Stat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,319,904 - 16,357,687 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,320,326 - 16,348,505 (-)NCBIChiLan1.0ChiLan1.0
STAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,313,324 - 42,388,442 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,313,324 - 42,388,568 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,465,342 - 40,540,460 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,718,869 - 37,794,039 (-)NCBINCBI36Build 36hg18NCBI36
Build 341737,718,868 - 37,794,039NCBI
Celera1737,120,227 - 37,194,843 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,230,024 - 36,304,785 (-)NCBIHuRef
CHM1_11740,701,045 - 40,776,137 (-)NCBICHM1_1
T2T-CHM13v2.01743,169,811 - 43,244,652 (-)NCBIT2T-CHM13v2.0
Stat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,777,632 - 100,830,447 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,775,924 - 100,830,366 (-)EnsemblGRCm39 Ensembl
GRCm3811100,886,806 - 100,939,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,885,098 - 100,939,540 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711100,748,124 - 100,800,825 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,702,900 - 100,755,601 (-)NCBIMGSCv36mm8
MGSCv3611101,663,341 - 101,716,042 (-)NCBIMGSCv36mm8
Celera11112,235,347 - 112,235,602 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.82NCBI
Stat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,311,528 - 86,363,513 (-)NCBIGRCr8
mRatBN7.21085,811,206 - 85,863,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,811,218 - 85,863,057 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,847,511 - 90,899,338 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,326,207 - 90,377,980 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,719,368 - 85,771,150 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,790,401 - 88,842,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,790,408 - 88,842,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,584,605 - 88,638,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,821,078 - 89,872,970 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,835,448 - 89,887,340 (-)NCBI
Celera1084,529,054 - 84,580,831 (-)NCBICelera
RH 3.4 Map10837.0RGD
Cytogenetic Map10q31NCBI
STAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,594,115 - 22,671,720 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,486,658 - 24,561,894 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,928,689 - 15,003,644 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,152,358 - 15,227,084 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,152,358 - 15,227,067 (+)Ensemblpanpan1.1panPan2
STAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,539,660 - 20,614,631 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,539,697 - 20,612,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,001,678 - 20,076,249 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,258,611 - 21,334,353 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,258,632 - 21,334,351 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,044,250 - 20,119,519 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,309,625 - 20,386,466 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,413,942 - 20,489,100 (+)NCBIUU_Cfam_GSD_1.0
Stat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,877,467 - 19,955,950 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,117,290 - 17,178,402 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,119,189 - 17,178,402 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,407,233 - 20,472,992 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,407,316 - 20,471,091 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,709,840 - 20,775,669 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,877,884 - 63,957,894 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,922,862 - 63,957,984 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,685,072 - 34,769,191 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,648,080 - 1,681,200 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,648,235 - 1,680,788 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Ensembl Acc Id: ENSCLAT00000021700   ⟹   ENSCLAP00000021497
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545116,319,904 - 16,348,505 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000021701   ⟹   ENSCLAP00000021498
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545116,320,353 - 16,357,687 (-)Ensembl
RefSeq Acc Id: XM_013519135   ⟹   XP_013374589
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545116,320,326 - 16,337,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013519137   ⟹   XP_013374591
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545116,320,326 - 16,348,505 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013519138   ⟹   XP_013374592
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545116,320,326 - 16,337,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013519139   ⟹   XP_013374593
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545116,320,326 - 16,337,157 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013374591   ⟸   XM_013519137
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YT68 (UniProtKB/TrEMBL),   A0A8C2YT69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013374592   ⟸   XM_013519138
- Peptide Label: isoform X3
- UniProtKB: A0A8C2YT69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013374589   ⟸   XM_013519135
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YT69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013374593   ⟸   XM_013519139
- Peptide Label: isoform X4
- UniProtKB: A0A8C2YT69 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000021498   ⟸   ENSCLAT00000021701
Ensembl Acc Id: ENSCLAP00000021497   ⟸   ENSCLAT00000021700
Protein Domains
SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021700 ENTREZGENE
  ENSCLAT00000021700.1 UniProtKB/TrEMBL
  ENSCLAT00000021701 ENTREZGENE
  ENSCLAT00000021701.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.532.10 UniProtKB/TrEMBL
  2.60.40.630 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  STAT transcription factor, all-alpha domain UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  STAT UniProtKB/TrEMBL
  STAT3_SH2 UniProtKB/TrEMBL
  STAT_linker UniProtKB/TrEMBL
  STAT_N_sf UniProtKB/TrEMBL
  STAT_TF_alpha UniProtKB/TrEMBL
  STAT_TF_coiled-coil UniProtKB/TrEMBL
  STAT_TF_DNA-bd UniProtKB/TrEMBL
  STAT_TF_DNA-bd_N UniProtKB/TrEMBL
  STAT_TF_prot_interaction UniProtKB/TrEMBL
NCBI Gene Stat3 ENTREZGENE
PANTHER PTHR11801 UniProtKB/TrEMBL
  SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  STAT_alpha UniProtKB/TrEMBL
  STAT_bind UniProtKB/TrEMBL
  STAT_int UniProtKB/TrEMBL
  STAT_linker UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
SMART STAT_int UniProtKB/TrEMBL
Superfamily-SCOP SSF47655 UniProtKB/TrEMBL
  SSF48092 UniProtKB/TrEMBL
  SSF49417 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C2YT68 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YT69 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Stat3  signal transducer and activator of transcription 3    signal transducer and activator of transcription 3 (acute-phase response factor)  Symbol and/or name change 5135510 APPROVED