GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | multiple interactions | EXP | | 6480464 | CTD | Cyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]; Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] | PMID:19299911 | Stat3 | increases expression | ISO | Stat3 (Mus musculus) | 6480464 | CTD | Cyclosporine results in increased expression of STAT3 protein | PMID:27585667 | Stat3 | increases phosphorylation | ISO | Stat3 (Mus musculus) | 6480464 | CTD | Cyclosporine results in increased phosphorylation of STAT3 protein | PMID:22155090 PMID:23958496 | Stat3 | multiple interactions | ISO | Stat3 (Mus musculus) | 6480464 | CTD | alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]; caffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]; Cyclosporine results in increased phosphorylation of and affects the localization of STAT3 protein; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of STAT3 protein]; TLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of STAT3 protein] | PMID:22155090 PMID:23958496 PMID:27585667 | | ||||||||||||||||||||||
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