GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | multiple interactions | ISO | Stat3 (Mus musculus) | 6480464 | CTD | Benzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]]; Benzoic Acid analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; Benzoic Acid analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein | PMID:26088127 | Stat3 | multiple interactions | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | Benzoic Acid analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Benzoic Acid analog inhibits the reaction [STAT3 protein binds to BCL2 promoter]; Benzoic Acid analog inhibits the reaction [STAT3 protein binds to BIRC5 promoter]; Benzoic Acid analog inhibits the reaction [STAT3 protein binds to NOS2 promoter]; Benzoic Acid analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein | PMID:26088127 | | ||||||||||||||||||||||
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