Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	3772
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Stat3
Name:	signal transducer and activator of transcription 3

Acc ID:	CHEBI:36706
Term:	resiquimod
Definition:	An imidazoquinoline that has formula C17H22N4O2.
Chemical ID:	MESH:C402365

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Stat3	increases expression	ISO	Stat3 (Mus musculus)	6480464	CTD	resiquimod results in increased expression of STAT3 mRNA	PMID:17238832

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.