Nr3c1 (nuclear receptor subfamily 3, group C, member 1) - Rat Genome Database

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Gene: Nr3c1 (nuclear receptor subfamily 3, group C, member 1) Rattus norvegicus
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Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
RGD ID: 2741
Description: Exhibits several functions, including heat shock protein binding activity; receptor tyrosine kinase binding activity; and transcription coactivator activity. Involved in several processes, including cellular response to magnesium ion; positive regulation of transcription, DNA-templated; and response to glucocorticoid. Localizes to several cellular components, including dendritic spine; glutamatergic synapse; and postsynaptic density, intracellular component. Used to study several diseases, including asthma; congestive heart failure; hypertension; obesity; and type 2 diabetes mellitus. Biomarker of several diseases, including brain disease (multiple); end stage renal disease; muscular atrophy; polycystic ovary syndrome; and post-traumatic stress disorder. Human ortholog(s) of this gene implicated in several diseases, including anorexia nervosa; lung disease (multiple); major depressive disorder; obesity; and renal cell carcinoma. Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1); PARTICIPATES IN cortisol signaling pathway; forkhead class A signaling pathway; prednisolone pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1,4-dithiothreitol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gcr; glucocorticoid receptor; GR; Grl; nuclear receptor subfamily 3 group C member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Nr3c1em1Kuan  
Genetic Models: SD-Nr3c1em1Kuan
Is Marker For: QTLs:   Bp46   Bp47   Scl22   Sprol1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21831,271,681 - 31,393,320 (-)NCBI
Rnor_6.0 Ensembl1831,728,373 - 31,749,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01831,728,373 - 32,704,022 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01831,408,742 - 31,442,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01832,347,227 - 32,348,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41832,371,496 - 32,459,145 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11832,406,765 - 32,494,411 (-)NCBI
Celera1830,905,394 - 30,993,522 (-)NCBICelera
RH 3.4 Map18442.9RGD
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
46, XX Disorders of Sex Development  (ISO)
anorexia nervosa  (ISO)
asthma  (IDA,ISO)
atrial fibrillation  (ISO)
bipolar disorder  (ISO)
brain ischemia  (IEP)
Burns  (IDA,IEP)
cataract  (IMP)
chronic obstructive pulmonary disease  (ISO)
Cocaine-Related Disorders  (ISO)
congestive heart failure  (IMP)
coronary artery disease  (ISO)
Cushing Syndrome  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
Edema  (IDA)
end stage renal disease  (IEP)
endometriosis  (ISO)
Endotoxemia  (IDA)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Diabetes Mellitus  (IEP)
Fetal Growth Retardation  (IDA,IEP)
Glucocorticoid Receptor Deficiency  (ISO)
glucose metabolism disease  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
hypertension  (IMP,ISO)
hypokalemia  (ISO)
interstitial lung disease  (ISO)
lipoid nephrosis  (ISO)
lung disease  (IEP,ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
major depressive disorder  (ISO)
Malocclusion  (IEP)
mental depression  (IEP,ISO)
mood disorder  (ISO)
muscular atrophy  (IEP)
nephrotic syndrome  (ISO)
nephrotic syndrome type 2  (ISO)
Neurodevelopmental Disorders  (ISO)
obesity  (IDA,ISO)
obstructive lung disease  (ISO)
obstructive sleep apnea  (ISO)
ocular hypertension  (ISO)
Perennial Allergic Rhinitis  (ISO)
polycystic ovary syndrome  (IEP)
post-traumatic stress disorder  (IEP)
primary biliary cholangitis  (ISO)
primary hyperaldosteronism  (ISS)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
psychotic disorder  (ISO)
pulmonary sarcoidosis  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (IEP)
schizophrenia  (ISO)
Sepsis  (IDA,ISO)
sinusitis  (ISO)
status epilepticus  (IEP)
Stroke  (IDA)
Transplant Rejection  (ISO)
type 2 diabetes mellitus  (IDA)
uveitis  (IEP)
visual epilepsy  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(3,4-dihydroxyphenyl)acetic acid  (ISO)
(S)-amphetamine  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2,3,4,7,8-Hexachlorodibenzofuran  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (EXP,ISO)
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-bromopropane  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
11-deoxycorticosterone  (EXP,ISO)
11-deoxycortisol  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17alpha-hydroxyprogesterone  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-aminophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,4-Dimethylbenzaldehyde  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (EXP,ISO)
3-phenoxybenzoic acid  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (ISO)
4'-hydroxydiclofenac  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
agomelatine  (ISO)
albuterol  (ISO)
aldehydo-D-glucose  (ISO)
aldosterone  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
amitriptyline  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic acid  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
Aurin  (ISO)
avobenzone  (ISO)
aziridines  (ISO)
beclomethasone  (EXP,ISO)
benzbromarone  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzoyl peroxide  (ISO)
betamethasone  (ISO)
bifenthrin  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
budesonide  (EXP,ISO)
butachlor  (ISO)
butanal  (ISO)
Butylparaben  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
celecoxib  (EXP)
chlorpromazine  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciclopirox  (ISO)
cidofovir anhydrous  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
citalopram  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP)
clotrimazole  (ISO)
clozapine  (ISO)
cobalt atom  (EXP)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
compound 48/80  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP,ISO)
corticotropin  (ISO)
cortisol  (EXP,ISO)
cortisone  (ISO)
cortivazol  (ISO)
coumestrol  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (EXP,ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
DDE  (ISO)
DDT  (ISO)
deflazacort  (ISO)
dehydroepiandrosterone  (ISO)
desipramine  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloromethane  (ISO)
diclofenac  (ISO)
Dicyclohexyl phthalate  (ISO)
diisopropyl fluorophosphate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endrin  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
ethiofencarb  (ISO)
ethyl myristate  (ISO)
fenchone  (ISO)
fenvalerate  (EXP)
fludrocortisone  (ISO)
flumethasone  (ISO)
fluoranthene  (ISO)
fluoxetine  (EXP,ISO)
flutamide  (EXP,ISO)
fluticasone  (EXP,ISO)
folic acid  (EXP,ISO)
folpet  (ISO)
formaldehyde  (ISO)
formoterol fumarate  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
Fusarenone X  (ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
ginsenoside Re  (ISO)
glafenine  (EXP)
glucose  (ISO)
hexadecanoic acid  (ISO)
homovanillic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (EXP,ISO)
idazoxan  (EXP)
irinotecan  (ISO)
isoquinolines  (ISO)
ketoconazole  (ISO)
L-1,4-dithiothreitol  (EXP,ISO)
L-ascorbic acid  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
lamotrigine  (ISO)
lead diacetate  (ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
leflunomide  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (EXP,ISO)
lithium chloride  (EXP)
lithium hydride  (EXP,ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP,ISO)
menadione  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (EXP)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylprednisolone aceponate  (ISO)
methylseleninic acid  (ISO)
methyltestosterone  (EXP)
miconazole  (ISO)
mifepristone  (EXP,ISO)
mirex  (EXP)
mitomycin C  (ISO)
mitoxantrone  (ISO)
molybdate  (EXP)
mometasone furoate  (EXP,ISO)
morphine  (EXP)
N,O-dimethyltyramine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-butylbenzenesulfonamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP,ISO)
nimesulide  (EXP)
nitric oxide  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (ISO)
pararosaniline free base  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
Phenoxybenzamine  (ISO)
phenylbutazone  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (EXP)
phosgene  (ISO)
pirinixic acid  (EXP,ISO)
Polygodial  (EXP)
potassium chloride  (EXP)
potassium chromate  (ISO)
prednisolone  (ISO)
prednisone  (ISO)
prednylidene  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (EXP,ISO)
promegestone  (ISO)
propiconazole  (ISO)
propylparaben  (ISO)
protoporphyrin  (ISO)
puromycin  (ISO)
quercetin  (EXP,ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
reserpine  (EXP)
resmethrin  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rimonabant  (ISO)
rotenone  (ISO)
S-methyl methanethiosulfonate  (EXP)
Salmeterol xinafoate  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
selenium atom  (ISO)
selenous acid  (ISO)
senecionine  (EXP)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
spiperone  (ISO)
spiroxamine  (ISO)
succimer  (ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
Tanshinone I  (ISO)
tauroursodeoxycholic acid  (EXP,ISO)
tenofovir disoproxil fumarate  (ISO)
terbutaline  (ISO)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetramethrin  (ISO)
tetraphene  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
thyroxine  (EXP)
titanium dioxide  (ISO)
tolcapone  (EXP)
tolterodine tartrate  (ISO)
tolylfluanid  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
triamcinolone  (ISO)
triamcinolone acetonide  (EXP,ISO)
tributyl phosphate  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (EXP,ISO)
trifluoperazine  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP,ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
undecan-2-one  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (EXP)
verapamil  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zinc atom  (EXP,ISO)
zinc oxide  (ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (ISO)
aging  (IEP)
androgen metabolic process  (IEP)
brain development  (IEP)
cellular response to dexamethasone stimulus  (IMP,ISO)
cellular response to glucocorticoid stimulus  (ISO,ISS)
cellular response to magnesium ion  (IEP)
cellular response to steroid hormone stimulus  (ISO,ISS)
cellular response to transforming growth factor beta stimulus  (ISO)
chromatin remodeling  (IMP)
chromatin-mediated maintenance of transcription  (IMP)
circadian rhythm  (IEP)
female pregnancy  (IEP)
glucocorticoid mediated signaling pathway  (IEA)
glucocorticoid metabolic process  (ISO)
glucocorticoid receptor signaling pathway  (ISO)
intracellular steroid hormone receptor signaling pathway  (IBA)
lung development  (IEP)
mammary gland duct morphogenesis  (ISO)
maternal behavior  (ISO)
muscle atrophy  (IEP)
negative regulation of apoptotic process  (IMP)
negative regulation of glucocorticoid mediated signaling pathway  (ISO)
negative regulation of synaptic plasticity  (IMP)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of vascular permeability  (IMP)
positive regulation of cell growth involved in cardiac muscle cell development  (IMP)
positive regulation of dendritic spine development  (IMP)
positive regulation of glucocorticoid receptor signaling pathway  (IDA)
positive regulation of glutamate secretion  (IMP)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
protein-containing complex assembly  (TAS)
regulation of cell population proliferation  (IDA)
regulation of glucocorticoid biosynthetic process  (ISO)
regulation of gluconeogenesis  (ISO)
regulation of glucose metabolic process  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
regulation of transcription, DNA-templated  (ISO)
response to activity  (IEP)
response to arsenic-containing substance  (IDA)
response to calcium ion  (IEP)
response to corticosterone  (IEP)
response to dexamethasone  (IEP)
response to electrical stimulus  (IEP)
response to inactivity  (IEP)
response to insulin  (IEP)
response to mercury ion  (IEP)
response to radiation  (IEP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Agresti A, etal., Mol Cell. 2005 Apr 1;18(1):109-21.
2. Arai Y, etal., Cancer Invest. 2008 Feb;26(1):35-40.
3. Arambasic J, etal., IUBMB Life. 2010 Mar;62(3):227-36.
4. Asadi A, etal., Biochem Biophys Res Commun. 2008 Apr 11;368(3):569-74. Epub 2008 Feb 7.
5. Bailey MA, etal., Hypertension. 2009 Oct;54(4):890-6. Epub 2009 Jul 27.
6. Bao GS, etal., Chin Med J (Engl). 2011 Sep;124(17):2622-7.
7. Baserga M, etal., Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1943-55. Epub 2007 Feb 1.
8. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
9. Belikov S, etal., Exp Cell Res. 2012 Jan 1;318(1):61-74. Epub 2011 Oct 6.
10. Bertorelli G, etal., Pulm Pharmacol Ther. 2008;21(1):214-21. Epub 2007 Mar 24.
11. Bo T, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2010 Mar;12(3):211-4.
12. Bodwell JE, etal., Chem Res Toxicol 2004 Aug;17(8):1064-76.
13. Bousquet E, etal., PLoS One. 2012;7(11):e49036. doi: 10.1371/journal.pone.0049036. Epub 2012 Nov 9.
14. Brkljacic J, etal., J Appl Toxicol. 2007 Jan-Feb;27(1):43-50.
15. Chen P, etal., Int Urol Nephrol. 2011 Mar;43(1):167-74. Epub 2010 Apr 24.
16. Chen W and Roeder RG, Nucleic Acids Res. 2007;35(18):6161-9. Epub 2007 Sep 7.
17. Corvol H, etal., Respir Res. 2007 Nov 29;8:88.
18. Cvoro A and Matic G, Int J Biochem Cell Biol 2002 Mar;34(3):279-85.
19. de Carvalho CR, etal., Sarcoidosis. 1990 Sep;7(2):93-5.
20. Duma D, etal., Crit Care Med. 2004 Nov;32(11):2304-10.
21. Earp JC, etal., J Pharmacol Exp Ther. 2008 Aug;326(2):532-45. Epub 2008 Apr 30.
22. Eberhardt W, etal., Mol Endocrinol. 2002 Aug;16(8):1752-66.
23. Ekuni D, etal., Neuromolecular Med. 2011 Sep;13(3):197-203. Epub 2011 Jul 13.
24. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
25. GOA data from the GO Consortium
26. Goldbart AD, etal., Pediatr Res. 2005 Feb;57(2):232-6. Epub 2004 Dec 20.
27. Grahammer F, etal., Gastroenterology. 2001 May;120(6):1363-71.
28. Han SH, etal., Nephrol Dial Transplant. 2008 Jan;23(1):169-75. Epub 2007 Sep 22.
29. He XJ, etal., Zhonghua Er Ke Za Zhi. 2005 Feb;43(2):109-12.
30. Hedman E, etal., Proteomics. 2006 May;6(10):3114-26.
31. Hsiao PW, etal., Mol Cell Biol. 2003 Sep;23(17):6210-20.
32. Ichimaru N, etal., Transpl Int. 2000;13(4):255-9.
33. Invitti C, etal., Biol Psychiatry. 1999 Jun 1;45(11):1467-71.
34. Isenovic ER, etal., Acta Biol Hung. 2006 Mar;57(1):37-48.
35. Ishida A, etal., Auris Nasus Larynx. 2010 Oct;37(5):584-8. Epub 2010 Feb 24.
36. Jing L and Bu M, Ann Clin Lab Sci. 2011 Fall;41(1):14-9.
37. Kaul S, etal., J Biol Chem 2002 Sep 27;277(39):36223-32.
38. Ke X, etal., Physiol Genomics. 2010 Jul 7;42(2):177-89. Epub 2010 Apr 13.
39. Kerr JE, etal., J Neuroendocrinol. 1996 Jun;8(6):439-47.
40. Komatsuzaki Y, etal., PLoS One. 2012;7(4):e34124. Epub 2012 Apr 11.
41. Korgun ET, etal., Folia Histochem Cytobiol. 2011;49(2):325-34.
42. Korn SH, etal., Respir Med. 1998 Sep;92(9):1102-9.
43. Kovacs P, etal., Biochem Biophys Res Commun 1997 Jun 18;235(2):343-8
44. Krishnamurthy P, etal., Horm Metab Res. 2008 Mar;40(3):194-8. Epub 2008 Feb 4.
45. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
46. Lee BH, etal., Neonatology. 2007;91(1):12-9. Epub 2006 Nov 10.
47. Lesage J, etal., Endocrinology 2001 May;142(5):1692-702.
48. Li M, etal., Neurol Sci. 2011 Aug;32(4):625-31. Epub 2011 May 17.
49. Li MQ, etal., Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007 Apr;25(4):215-9.
50. Lin H, etal., Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1995 Mar;11(2):103-5.
51. Lin RC, etal., Hypertension. 2003 Mar;41(3):404-7. Epub 2003 Feb 10.
52. Liu C, etal., J Pharmacol Exp Ther. 2011 Oct;339(1):203-9. Epub 2011 Jul 7.
53. Liu DH, etal., Crit Care Med. 2002 Mar;30(3):623-7.
54. Liu L, etal., Zhongguo Zhong Yao Za Zhi. 2011 May;36(10):1342-7.
55. Liu T, etal., Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2010 Apr;32(2):147-50. doi: 10.3881/j.issn.1000-503X.2010.02.004.
56. Liu W, etal., Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12480-4.
57. Lu X, etal., Zhong Xi Yi Jie He Xue Bao. 2009 Feb;7(2):121-4.
58. Luo D, etal., Zhonghua Gan Zang Bing Za Zhi 2002 Jun;10(3):231.
59. Lyu J, etal., Invest Ophthalmol Vis Sci. 2003 May;44(5):2034-40.
60. Macdougall MJ and Howland JG, Cereb Cortex. 2012 Aug 23.
61. Marissal-Arvy N, etal., Metabolism. 2010 Aug 17.
62. Marti A, etal., BMC Med Genet. 2006 May 25;7:50.
63. Meng QY, etal., Mol Cell Endocrinol. 2011 Aug 6;342(1-2):54-63. Epub 2011 Jun 1.
64. MGD data from the GO Consortium
65. Michea L, etal., Hypertension. 2008 Aug;52(2):295-300. Epub 2008 Jun 30.
66. Miesfeld R, etal., Cell 1986 Aug 1;46(3):389-99.
67. Nordquist J, etal., Mol Med. 2007 Sep-Oct;13(9-10):461-70.
68. Numakawa T, etal., Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):647-52. doi: 10.1073/pnas.0800888106. Epub 2009 Jan 6.
69. Ogino H, etal., J Infect Chemother. 2009 Apr;15(2):113-7. Epub 2009 Apr 25.
70. OMIM Disease Annotation Pipeline
71. Ostlund Farrants AK, etal., Mol Cell Biol 1997 Feb;17(2):895-905.
72. Park E, etal., J Obstet Gynaecol Res. 2012 Feb;38(2):396-407. doi: 10.1111/j.1447-0756.2011.01705.x. Epub 2011 Dec 19.
73. Peijie B, etal., J Sports Med Phys Fitness. 2007 Jun;47(2):246-9.
74. Perez H, etal., Neurosci Lett. 2010 Oct 8;483(1):41-6. Epub 2010 Jul 30.
75. Perisic T, etal., Respiration. 2009;77(1):70-5. Epub 2008 Sep 18.
76. Pietras T, etal., Mol Biol Rep. 2010 Nov 27.
77. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
78. Pipeline to import SMPDB annotations from SMPDB into RGD
79. Prager EM, etal., PLoS One. 2010 Dec 15;5(12):e14344.
80. Pratt WB, etal., Handb Exp Pharmacol. 2006;(172):111-38.
81. Ren R, etal., Endocrinology. 2012 Nov;153(11):5346-60. doi: 10.1210/en.2012-1563. Epub 2012 Sep 18.
82. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
83. RGD automated import pipeline for gene-chemical interactions
84. Roth M, etal., N Engl J Med. 2004 Aug 5;351(6):560-74.
85. Ruiz N, etal., Brain Res. 2011 Dec 2;1426:86-95. Epub 2011 Oct 8.
86. Saldiva PH, etal., Chest. 1985 Sep;88(3):417-9.
87. Samtani MN, etal., J Pharmacol Exp Ther. 2006 Apr;317(1):127-38. Epub 2005 Dec 21.
88. Sato S, etal., J Toxicol Sci. 2011;36(4):479-86.
89. Sato S, etal., Life Sci. 2011 Dec 19;89(25-26):962-7. Epub 2011 Oct 20.
90. Shi KH, etal., Zhong Xi Yi Jie He Xue Bao. 2010 Aug;8(8):785-9.
91. Silvestrini G, etal., Eur J Histochem. 2003;47(3):245-52.
92. Sola S, etal., Hepatology. 2005 Oct;42(4):925-34.
93. Szpirer C, etal., Mamm Genome 1998 Sep;9(9):721-34
94. Takano K, etal., J Pharmacol Exp Ther. 2011 Feb;336(2):381-90. Epub 2010 Nov 5.
95. Takaya J, etal., Ann Nutr Metab. 2011;59(2-4):73-8. Epub 2011 Dec 2.
96. Tao T, etal., Am J Respir Cell Mol Biol. 2006 Dec;35(6):668-80. Epub 2006 Jun 29.
97. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
98. ter Borg PC, etal., Neth J Med. 2004 Oct;62(9):326-31.
99. Tronche F, etal., Nat Genet. 1999 Sep;23(1):99-103.
100. Tziraki AA, etal., Clin Biochem. 2007 Nov;40(16-17):1188-93. Epub 2007 Aug 21.
101. van den Brandt J, etal., Am J Pathol. 2007 Mar;170(3):1041-53.
102. Wang CC and Wang SJ, Synapse. 2009 Sep;63(9):745-51.
103. Wang TM, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2010 Jan;12(1):47-50.
104. Watanabe S and Suzaki H, In Vivo. 2008 Jan-Feb;22(1):37-42.
105. Widen C, etal., Biochem J. 2003 Jul 1;373(Pt 1):211-20.
106. Wong EY and Herbert J, Eur J Neurosci. 2005 Aug;22(4):785-92.
107. Wu XL, etal., Chin J Integr Med. 2011 Apr;17(4):277-82. Epub 2011 Apr 21.
108. Wu YX, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011 Jul;23(7):426-9.
109. Yakirevich E, etal., Hum Pathol. 2011 Nov;42(11):1684-92. Epub 2011 Apr 29.
110. Yao Z, etal., Pharm Res. 2006 Apr;23(4):670-9. Epub 2006 Feb 2.
111. Yi SS, etal., Neurochem Res. 2009 May;34(5):851-8. Epub 2008 Aug 29.
112. Zhang T, etal., Genome Res 2004 Jan;14(1):79-89. Epub 2003 Dec 12.
113. Zhang Y, etal., Clin Exp Pharmacol Physiol. 2010 Nov;37(11):1044-8. doi: 10.1111/j.1440-1681.2010.05429.x.
114. Zhang Z, etal., J Biol Chem. 2013 Jan 4;288(1):42-58. doi: 10.1074/jbc.M112.427740. Epub 2012 Nov 17.
115. Zhao M, etal., Invest Ophthalmol Vis Sci. 2011 Aug 11;52(9):6340-7. Print 2011 Sep.
116. Zinker B, etal., Metabolism. 2007 Mar;56(3):380-7.
117. Zucchi FC, etal., Exp Transl Stroke Med. 2010 Sep 22;2(1):18.
Additional References at PubMed
PMID:1751485   PMID:1865905   PMID:1894621   PMID:1936288   PMID:1939229   PMID:2115209   PMID:3191912   PMID:3216865   PMID:3684608   PMID:7628695   PMID:7883868   PMID:7914432  
PMID:8191545   PMID:8257681   PMID:8450530   PMID:8493115   PMID:9111344   PMID:9237103   PMID:9353307   PMID:9603939   PMID:9892017   PMID:10224232   PMID:10364267   PMID:10480874  
PMID:10509797   PMID:10744634   PMID:10770488   PMID:10866662   PMID:11278286   PMID:11435610   PMID:11555636   PMID:11739747   PMID:11809422   PMID:11812797   PMID:12118039   PMID:12198239  
PMID:12489571   PMID:12902338   PMID:14659477   PMID:14960289   PMID:14978266   PMID:15016838   PMID:15044366   PMID:15060156   PMID:15071092   PMID:15199138   PMID:15539428   PMID:15580339  
PMID:15731366   PMID:15769988   PMID:15870285   PMID:15932935   PMID:15940303   PMID:16150424   PMID:16297316   PMID:16580234   PMID:16644723   PMID:16728402   PMID:16897719   PMID:16899232  
PMID:17081986   PMID:17210632   PMID:17244200   PMID:17347454   PMID:17367809   PMID:17370312   PMID:17481888   PMID:17552876   PMID:17635946   PMID:17644267   PMID:17689506   PMID:17690167  
PMID:17927667   PMID:17982481   PMID:18427988   PMID:18434352   PMID:18524780   PMID:18534262   PMID:18583028   PMID:18615595   PMID:18625317   PMID:18643788   PMID:18650268   PMID:18725247  
PMID:18829866   PMID:19007760   PMID:19065825   PMID:19118409   PMID:19131573   PMID:19141540   PMID:19145310   PMID:19195790   PMID:19279295   PMID:19293335   PMID:19372434   PMID:19406955  
PMID:19463811   PMID:19521113   PMID:19562035   PMID:19563881   PMID:19596457   PMID:19628874   PMID:19638349   PMID:19665541   PMID:19684579   PMID:19782950   PMID:19816761   PMID:19833863  
PMID:19875699   PMID:19953342   PMID:20223255   PMID:20371704   PMID:20413910   PMID:20573576   PMID:20660300   PMID:20660302   PMID:20861076   PMID:21076867   PMID:21180159   PMID:21245955  
PMID:21463019   PMID:21835217   PMID:22022502   PMID:22253850   PMID:22350213   PMID:22371232   PMID:22456310   PMID:22579827   PMID:22622902   PMID:22641130   PMID:22715380   PMID:22717988  
PMID:22750445   PMID:22957049   PMID:22971526   PMID:23023726   PMID:23071095   PMID:23084728   PMID:23132854   PMID:23159706   PMID:23169346   PMID:23185000   PMID:23195113   PMID:23257260  
PMID:23279724   PMID:23290935   PMID:23358504   PMID:23460384   PMID:23508108   PMID:23525215   PMID:23683655   PMID:23686112   PMID:23728292   PMID:23823477   PMID:23846420   PMID:23878391  
PMID:24097989   PMID:24334056   PMID:24420787   PMID:24721039   PMID:25114262   PMID:25218493   PMID:25510864   PMID:25633096   PMID:25687413   PMID:25972460   PMID:26180184   PMID:26287126  
PMID:26305887   PMID:26333123   PMID:26452320   PMID:26482332   PMID:26504077   PMID:26593036   PMID:26598419   PMID:26779948   PMID:27334923   PMID:27686098   PMID:28200020   PMID:28212940  
PMID:28324065   PMID:28414132   PMID:28696809   PMID:28916632   PMID:29218729   PMID:29522858   PMID:29729371   PMID:29845273   PMID:30101500   PMID:30170158   PMID:30532228   PMID:31071644  
PMID:31139184   PMID:31914623  


Genomics

Comparative Map Data
Nr3c1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21831,271,681 - 31,393,320 (-)NCBI
Rnor_6.0 Ensembl1831,728,373 - 31,749,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01831,728,373 - 32,704,022 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01831,408,742 - 31,442,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01832,347,227 - 32,348,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41832,371,496 - 32,459,145 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11832,406,765 - 32,494,411 (-)NCBI
Celera1830,905,394 - 30,993,522 (-)NCBICelera
RH 3.4 Map18442.9RGD
Cytogenetic Map18p11NCBI
NR3C1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5143,277,931 - 143,435,512 (-)EnsemblGRCh38hg38GRCh38
GRCh385143,277,931 - 143,435,512 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375142,657,496 - 142,815,077 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365142,637,689 - 142,795,270 (-)NCBINCBI36hg18NCBI36
Build 345142,639,324 - 142,763,087NCBI
Celera5138,738,770 - 138,896,297 (-)NCBI
Cytogenetic Map5q31.3NCBI
HuRef5137,804,733 - 137,962,312 (-)NCBIHuRef
CHM1_15142,091,205 - 142,248,804 (-)NCBICHM1_1
Nr3c1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391839,543,598 - 39,652,485 (-)NCBIGRCm39mm39
GRCm39 Ensembl1839,543,598 - 39,652,474 (-)Ensembl
GRCm381839,410,545 - 39,519,421 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1839,410,545 - 39,519,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv371839,570,199 - 39,646,899 (-)NCBIGRCm37mm9NCBIm37
MGSCv361839,537,961 - 39,615,820 (-)NCBImm8
Celera1840,761,405 - 40,838,026 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1821.09NCBI
Nr3c1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541510,494,640 - 10,586,221 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541510,494,704 - 10,585,778 (+)NCBIChiLan1.0ChiLan1.0
NR3C1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15144,741,452 - 144,865,341 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5144,741,452 - 144,865,269 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05138,634,278 - 139,089,171 (-)NCBIMhudiblu_PPA_v0panPan3
NR3C1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1238,124,568 - 38,242,510 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl238,123,190 - 38,240,755 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha235,173,176 - 35,283,390 (-)NCBI
ROS_Cfam_1.0238,573,084 - 38,692,463 (-)NCBI
UMICH_Zoey_3.1235,654,977 - 35,765,222 (-)NCBI
UNSW_CanFamBas_1.0236,468,553 - 36,579,023 (-)NCBI
UU_Cfam_GSD_1.0237,270,194 - 37,380,458 (-)NCBI
Nr3c1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213149,386,116 - 149,482,864 (+)NCBI
SpeTri2.0NW_00493650410,960,069 - 11,056,834 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR3C1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2144,822,937 - 144,956,095 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12144,822,937 - 144,956,451 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22151,051,816 - 151,185,046 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NR3C1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12345,904,926 - 46,031,804 (-)NCBI
ChlSab1.1 Ensembl2345,904,873 - 46,031,125 (-)Ensembl
Nr3c1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247742,496,276 - 2,603,894 (-)NCBI

Position Markers
D18Mit5  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01832,670,352 - 32,670,473NCBIRnor6.0
Rnor_5.01832,348,154 - 32,348,275UniSTSRnor5.0
RGSC_v3.41832,458,819 - 32,458,940UniSTSRGSC3.4
RGSC_v3.11832,494,084 - 32,494,206RGD
Celera1830,993,196 - 30,993,317UniSTS
SHRSP x BN Map1817.1599RGD
SHRSP x BN Map1817.1599UniSTS
Cytogenetic Map18p12UniSTS
D18Wox8  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01832,348,153 - 32,348,275NCBIRnor5.0
RGSC_v3.41832,458,819 - 32,458,940UniSTSRGSC3.4
Celera1830,993,196 - 30,993,317UniSTS
RH 2.0 Map18490.0RGD
SHRSP x BN Map1817.1599UniSTS
AW529964  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01831,730,426 - 31,730,581NCBIRnor6.0
Rnor_5.01831,410,795 - 31,410,950UniSTSRnor5.0
RGSC_v3.41832,373,549 - 32,373,704UniSTSRGSC3.4
Celera1830,907,447 - 30,907,602UniSTS
RH 3.4 Map18442.7UniSTS
Cytogenetic Map18p12UniSTS
RH94419  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01831,731,912 - 31,732,064NCBIRnor6.0
Rnor_5.01831,412,281 - 31,412,433UniSTSRnor5.0
RGSC_v3.41832,375,035 - 32,375,187UniSTSRGSC3.4
Celera1830,908,933 - 30,909,085UniSTS
RH 3.4 Map18442.9UniSTS
Cytogenetic Map18p12UniSTS
NR3C1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01832,669,773 - 32,670,236NCBIRnor6.0
Rnor_5.01832,347,575 - 32,348,038UniSTSRnor5.0
RGSC_v3.41832,458,240 - 32,458,703UniSTSRGSC3.4
Celera1830,992,617 - 30,993,080UniSTS
Cytogenetic Map18p12UniSTS
D18Mit17  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01832,670,288 - 32,670,507NCBIRnor6.0
Rnor_5.01832,348,090 - 32,348,309UniSTSRnor5.0
RGSC_v3.41832,458,755 - 32,458,974UniSTSRGSC3.4
Celera1830,993,132 - 30,993,351UniSTS
Cytogenetic Map18p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135097280Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18138195967Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18138195967Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18138753381Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18371954732487870Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18440751362570466Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18543013441781619Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181467885259678852Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181553296332704022Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553296332704022Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181553942732670473Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553942753861431Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181553942761499684Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553967161985648Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181569587268524999Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181569587287080053Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181569587287080053Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181903103068436105Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181925171732670473Rat
1331735Rf44Renal function QTL 442.981total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181925171732670473Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)182028575887080053Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142163949166639491Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182260373687074531Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182260476461985648Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182318422753861431Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182596102681761656Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182674340443659626Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182774302448499517Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182774302448499517Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182774302448499517Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182774302448499517Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182774302448499517Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182774302448499517Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182774302448499517Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)183053361475533614Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)183053361475533614Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)183053361475533614Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183136134176361341Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183136134176361341Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183136134176361341Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183136134176361341Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183160842476608424Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183172837362570429Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183267035261985812Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035263897621Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183267035273016546Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183267035287080053Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267047361985648Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183270402280696226Rat


Genetic Models
This gene Nr3c1 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1042
Count of miRNA genes:348
Interacting mature miRNAs:478
Transcripts:ENSRNOT00000019409, ENSRNOT00000044287
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 57 41 19 41 8 10 38 35 31 11 8
Low 2 1 36 10
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB115420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC096226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF455050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ271870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY066016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY293740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB699574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF495208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y12264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000044287   ⟹   ENSRNOP00000044335
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1831,728,373 - 31,749,647 (-)Ensembl
RefSeq Acc Id: NM_012576   ⟹   NP_036708
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,271,681 - 31,359,735 (-)NCBI
Rnor_6.01831,728,373 - 32,670,678 (-)NCBI
Rnor_5.01831,408,742 - 31,442,725 (-)NCBI
Rnor_5.01832,347,227 - 32,348,480 (-)NCBI
RGSC_v3.41832,371,496 - 32,459,145 (-)RGD
Celera1830,905,394 - 30,993,522 (-)RGD
Sequence:
RefSeq Acc Id: XM_008772065   ⟹   XP_008770287
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,273,365 - 31,362,278 (-)NCBI
Rnor_6.01831,728,373 - 32,672,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600839   ⟹   XP_017456328
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,271,681 - 31,362,278 (-)NCBI
Rnor_6.01831,728,373 - 32,672,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600840   ⟹   XP_017456329
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,275,610 - 31,361,837 (-)NCBI
Rnor_6.01831,728,373 - 32,672,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600841   ⟹   XP_017456330
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,275,610 - 31,363,144 (-)NCBI
Rnor_6.01831,728,373 - 32,673,965 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600842   ⟹   XP_017456331
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01831,728,373 - 32,674,236 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600843   ⟹   XP_017456332
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,275,610 - 31,393,320 (-)NCBI
Rnor_6.01831,728,373 - 32,704,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600844   ⟹   XP_017456333
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,275,610 - 31,363,460 (-)NCBI
Rnor_6.01831,728,373 - 32,674,418 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096566   ⟹   XP_038952494
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,272,716 - 31,363,143 (-)NCBI
RefSeq Acc Id: XM_039096567   ⟹   XP_038952495
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21831,275,610 - 31,362,278 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_036708   ⟸   NM_012576
- UniProtKB: P06536 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008770287   ⟸   XM_008772065
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456332   ⟸   XM_017600843
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456333   ⟸   XM_017600844
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456331   ⟸   XM_017600842
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456330   ⟸   XM_017600841
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456328   ⟸   XM_017600839
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456329   ⟸   XM_017600840
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000044335   ⟸   ENSRNOT00000044287
RefSeq Acc Id: XP_038952494   ⟸   XM_039096566
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952495   ⟸   XM_039096567
- Peptide Label: isoform X3
Protein Domains
NR LBD   Nuclear receptor

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV