Gene: Nr3c1 (nuclear receptor subfamily 3, group C, member 1) Rattus norvegicus
Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Description: Exhibits several functions, including heat shock protein binding activity, nucleic acid binding activity, and protein dimerization activity; involved in several processes, including animal organ development, chromatin organization, and positive regulation of cell differentiation; localizes to several cellular components, including the cytoplasm, dendritic spine, and glutamatergic synapse; used to study several diseases, including asthma, cataract, congestive heart failure, hypertension, and obesity; biomarker of several diseases, including brain ischemia, end stage renal failure, epilepsy (multiple), eye disease (multiple), and lung disease; orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1); PARTICIPATES IN cortisol signaling pathway; forkhead class A signaling pathway; prednisolone pharmacodynamics pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gcr; glucocorticoid receptor; GR; Grl; nuclear receptor subfamily 3 group C member 1
Is Marker For: QTLs:   Bp46   Bp47   Scl22   Sprol1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01831,728,373 - 32,704,022 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01832,347,227 - 32,348,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01831,408,742 - 31,442,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41832,371,496 - 32,459,145 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11832,406,765 - 32,494,411 (-)NCBI
Celera1830,905,394 - 30,993,522 (-)NCBICelera
Cytogenetic Map18p11NCBI
RH 3.4 Map18442.9RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)