STAT3 (signal transducer and activator of transcription 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: STAT3 (signal transducer and activator of transcription 3) Chlorocebus sabaeus
Analyze
Symbol: STAT3
Name: signal transducer and activator of transcription 3
RGD ID: 18657272
Description: ENCODES a protein that exhibits CCR5 chemokine receptor binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN acute-phase response (ortholog); cellular response to cytokine stimulus (ortholog); glucose homeostasis (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; Interleukin-10 signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); adenocarcinoma (ortholog); adult T-cell leukemia/lymphoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,877,884 - 63,957,894 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,922,862 - 63,957,984 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,685,072 - 34,769,191 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 109 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green MonkeyAlzheimer's disease  ISOStat3 (Mus musculus)9068941protein:decreased tyrosine phosphorylation:dentate gyrus and CA1 field of hippocampus RGDPMID:18813209 and REF_RGD_ID:10403051
STAT3Green MonkeyAlzheimer's disease  ISOSTAT3 (Homo sapiens)9068941protein:decreased tyrosine phosphorylation:dentate gyrusRGDPMID:18813209 and REF_RGD_ID:10403051
STAT3Green Monkeyangiomyolipoma  ISOSTAT3 (Homo sapiens)9068941protein:increased tyrosine phosphorylation:kidneyRGDPMID:15994429 and REF_RGD_ID:2298537
STAT3Green Monkeyangiosarcoma  ISOSTAT3 (Homo sapiens)9068941protein:increased phosphorylation:blood vesselRGDPMID:18700251 and REF_RGD_ID:8694308
STAT3Green Monkeyatherosclerosis  ISOStat3 (Rattus norvegicus)9068941associated with type 2 diabetes mellitus more ...RGDPMID:33889291 and REF_RGD_ID:329849122
STAT3Green Monkeyautistic disorder  ISOStat3 (Mus musculus)9068941 RGDPMID:19766327 and REF_RGD_ID:6483028
STAT3Green Monkeybacterial pneumonia  ISOStat3 (Mus musculus)9068941 RGDPMID:18192501 and REF_RGD_ID:6892945
STAT3Green MonkeyBehcet's disease no_associationISOSTAT3 (Homo sapiens)9068941DNA:SNP: :rs744166 and rs2293152 (human)RGDPMID:23127549 and REF_RGD_ID:8694309
STAT3Green MonkeyBehcet's disease  ISOSTAT3 (Homo sapiens)9068941DNA:SNP: :rs2293152 (human)RGDPMID:22205606 and REF_RGD_ID:6483021
STAT3Green MonkeyBrain Injuries  ISOStat3 (Rattus norvegicus)9068941protein:increased phosphorylation:brainRGDPMID:22145815 and REF_RGD_ID:8694312
STAT3Green MonkeyBrain Injuries  ISOStat3 (Rattus norvegicus)9068941 RGDPMID:21596098 more ...
STAT3Green Monkeybreast cancer disease_progressionISOSTAT3 (Homo sapiens)9068941 RGDPMID:22374428 and REF_RGD_ID:8694288
STAT3Green Monkeybreast cancer treatmentISOSTAT3 (Homo sapiens)9068941 RGDPMID:15374974 more ...
STAT3Green Monkeybreast cancer susceptibilityISOSTAT3 (Homo sapiens)9068941DNA:snpRGDPMID:17639043 and REF_RGD_ID:2291912
STAT3Green Monkeycardiomyopathy  ISOStat3 (Mus musculus)9068941 RGDPMID:23619365 and REF_RGD_ID:7495791
STAT3Green Monkeycervix uteri carcinoma in situ disease_progressionISOSTAT3 (Homo sapiens)9068941protein:increased serine phosphorylation:cervix epitheliumRGDPMID:16005944 and REF_RGD_ID:2298536
STAT3Green Monkeycervix uteri carcinoma in situ  ISOSTAT3 (Homo sapiens)9068941protein:increased expression:nucleusRGDPMID:17110342 and REF_RGD_ID:2291916
STAT3Green MonkeyChoroidal Neovascularization treatmentISOStat3 (Mus musculus)9068941 RGDPMID:17525280 and REF_RGD_ID:8694307
STAT3Green MonkeyChoroidal Neovascularization treatmentISOStat3 (Mus musculus)9068941associated with Diabetes Mellitus and ExperimentalRGDPMID:23094067 and REF_RGD_ID:10403057
STAT3Green MonkeyChronic Hepatitis C severityISOSTAT3 (Homo sapiens)9068941 RGDPMID:17318196 and REF_RGD_ID:8694293
1 to 20 of 109 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green Monkeydiffuse large B-cell lymphoma  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Diffuse large B cell lymphomaClinVarPMID:21690253 more ...
STAT3Green Monkeyfollicular dendritic cell sarcoma  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: EBV-Positive Inflammatory Follicular Dendritic Cell SarcomaClinVarPMID:24797340 more ...
STAT3Green Monkeygenetic disease  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:20816194 more ...
STAT3Green Monkeygrowth hormone insensitivity syndrome with immune dysregulation 1  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Growth hormone insensitivity with immune dysregulation 1 and autosomal recessiveClinVarPMID:28492532
STAT3Green Monkeyhyper IgE recurrent infection syndrome 1  ISOSTAT3 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
STAT3Green Monkeyhyper IgE syndrome  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Hyper-IgE syndromeClinVarPMID:17881745 more ...
STAT3Green MonkeyMultisystem Autoimmune Disease, Infantile-Onset, 1  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: STAT3-related early-onset multisystem autoimmune diseaseClinVarPMID:16199547 more ...
STAT3Green Monkeyprimary immunodeficiency disease  ISOSTAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Inherited Immunodeficiency DiseasesClinVarPMID:17676033 more ...
1 to 20 of 56 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green Monkeyacute myeloid leukemia  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19796711
STAT3Green Monkeyadenocarcinoma  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19028472 and PMID:26432044
STAT3Green Monkeyadult T-cell leukemia/lymphoma  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:24090995
STAT3Green Monkeyanaplastic large cell lymphoma  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22155737
STAT3Green MonkeyAnimal Disease Models  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25812446
STAT3Green MonkeyAnimal Mammary Neoplasms  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16316942
STAT3Green Monkeyatherosclerosis  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19330073
STAT3Green MonkeyAtrophy  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16391472
STAT3Green Monkeyautoimmune disease  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25038750
STAT3Green MonkeyB-lymphoblastic leukemia/lymphoma  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19796711
STAT3Green Monkeybrain ischemia  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17901229
STAT3Green MonkeyBreast Neoplasms  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:14975756
STAT3Green Monkeycarcinoma  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16316942
STAT3Green MonkeyCardiomegaly  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:10618415 more ...
STAT3Green Monkeycardiomyopathy  ISOSTAT3 (Homo sapiens)9068941CTD more ...CTDPMID:10618415 and PMID:24448315
STAT3Green MonkeyChemical and Drug Induced Liver Injury  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: therapeuticCTDPMID:38460807
STAT3Green MonkeyChronic Hepatitis  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22879914
STAT3Green MonkeyColonic Neoplasms  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:19028472
STAT3Green Monkeycongenital diaphragmatic hernia  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25812446
STAT3Green Monkeycongestive heart failure  ISOSTAT3 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:36071497
1 to 20 of 56 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green Monkeycolorectal cancer  ISOStat3 (Mus musculus)9068941OMIM:114500 more ...MouseDO 
STAT3Green Monkeyinflammatory bowel disease  ISOStat3 (Mus musculus)9068941 MouseDO 
STAT3Green Monkeyperipartum cardiomyopathy  ISOStat3 (Mus musculus)9068941 MouseDO 
STAT3Green Monkeypsoriasis  ISOStat3 (Mus musculus)9068941 MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green Monkeyhyper IgE recurrent infection syndrome 1  ISOSTAT3 (Homo sapiens)7240710 OMIM 
STAT3Green MonkeyMultisystem Autoimmune Disease, Infantile-Onset, 1  ISOSTAT3 (Homo sapiens)7240710 OMIM 


Biological Process
1 to 20 of 98 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green Monkeyacute-phase response  ISOStat3 (Rattus norvegicus)9068941 RGDPMID:8530402 and REF_RGD_ID:730023
STAT3Green Monkeyastrocyte differentiation involved_inIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycell differentiation involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycell population proliferation acts_upstream_of_or_withinIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycell surface receptor signaling pathway via JAK-STAT involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycell surface receptor signaling pathway via STAT involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycellular response to cytokine stimulus acts_upstream_of_or_withinISOStat3 (Rattus norvegicus)9068941PMID:19414010MGIPMID:19414010 and REF_RGD_ID:10402041
STAT3Green Monkeycellular response to hormone stimulus involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycellular response to interleukin-17 involved_inIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycellular response to leptin stimulus involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycytokine-mediated signaling pathway involved_inIEAARBA:ARBA00028236150520179 UniProtGO_REF:0000117
STAT3Green Monkeyeating behavior acts_upstream_of_or_withinIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyenergy homeostasis involved_inIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeygene expression involved_inIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyglucose homeostasis acts_upstream_of_or_withinIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyglucose homeostasis involved_inISOStat3 (Mus musculus)9068941 PMID:12594516UniProtPMID:12594516
STAT3Green Monkeygrowth hormone receptor signaling pathway involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeygrowth hormone receptor signaling pathway via JAK-STAT involved_inIEAUniProtKB:P40763 more ...150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyinflammatory response involved_inIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyinterleukin-10-mediated signaling pathway involved_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
1 to 20 of 98 rows

Cellular Component
1 to 20 of 27 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green Monkeychromatin located_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
STAT3Green Monkeycytoplasm is_active_inISOSTAT3 (Homo sapiens)9068941 PMID:12743296UniProtPMID:12743296
STAT3Green Monkeycytoplasm located_inIEAARBA:ARBA00026971150520179 UniProtGO_REF:0000117
STAT3Green Monkeycytoplasm is_active_inISOStat3 (Mus musculus)9068941 PMID:16025117UniProtPMID:16025117
STAT3Green Monkeycytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
STAT3Green Monkeycytoplasm located_inIEAUniRule:UR000046415150520179 UniProtGO_REF:0000104
STAT3Green Monkeycytoplasm located_inIEAUniProtKB:P40763 more ...150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycytosol located_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeycytosol  ISOStat3 (Rattus norvegicus)9068941 RGDPMID:23884942 and REF_RGD_ID:8694331
STAT3Green Monkeyglutamatergic synapse is_active_inISOStat3 (Rattus norvegicus)9068941PMID:22284190SynGOPMID:22284190 and REF_RGD_ID:13702421
STAT3Green Monkeymitochondrial inner membrane located_inISOStat3 (Rattus norvegicus)9068941PMID:23271731UniProtPMID:23271731 and REF_RGD_ID:8554545
STAT3Green Monkeymitochondrial inner membrane  ISOStat3 (Rattus norvegicus)9068941 RGDPMID:23271731 and REF_RGD_ID:8554545
STAT3Green Monkeynucleoplasm located_inIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeynucleus is_active_inISOStat3 (Mus musculus)9068941 PMID:27830702UniProtPMID:27830702
STAT3Green Monkeynucleus  ISOStat3 (Rattus norvegicus)9068941 RGDPMID:23884942 and REF_RGD_ID:8694331
STAT3Green Monkeynucleus located_inIEAUniRule:UR000046415150520179 UniProtGO_REF:0000104
STAT3Green Monkeynucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
STAT3Green Monkeynucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
STAT3Green Monkeynucleus located_inIEAUniProtKB:P40763 more ...150520179 EnsemblGO_REF:0000107
1 to 20 of 27 rows

Molecular Function
1 to 20 of 112 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
STAT3Green MonkeyCCR5 chemokine receptor binding  ISOCcr5 (Rattus norvegicus)9068941 RGDPMID:14674010 and REF_RGD_ID:1582346
STAT3Green Monkeychromatin DNA binding enablesIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green MonkeyDNA binding  ISOStat3 (Rattus norvegicus)9068941 RGDPMID:8530402 and REF_RGD_ID:730023
STAT3Green MonkeyDNA binding enablesIEAUniProtKB-KW:KW-0238150520179 UniProtGO_REF:0000043
STAT3Green MonkeyDNA binding enablesIEAUniProtKB:P42227 and ensembl:ENSMUSP00000120152150520179 EnsemblGO_REF:0000107
STAT3Green MonkeyDNA binding enablesIEAInterPro:IPR013801150520179 InterProGO_REF:0000002
STAT3Green MonkeyDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green MonkeyDNA-binding transcription factor activity enablesIEAARBA:ARBA00028295150520179 UniProtGO_REF:0000117
STAT3Green MonkeyDNA-binding transcription factor activity enablesIEAInterPro:IPR001217 and InterPro:IPR008967150520179 InterProGO_REF:0000002
STAT3Green MonkeyDNA-binding transcription factor activity enablesIEAUniProtKB:P40763 more ...150520179 EnsemblGO_REF:0000107
STAT3Green MonkeyDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAUniProtKB:P40763 more ...150520179 EnsemblGO_REF:0000107
STAT3Green MonkeyDNA-binding transcription factor binding enablesIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green MonkeyDNA-binding transcription factor binding  ISOStat5b (Rattus norvegicus)9068941 RGDPMID:16527988 and REF_RGD_ID:1601384
STAT3Green Monkeyidentical protein binding enablesIEAUniProtKB:P40763 more ...150520179 EnsemblGO_REF:0000107
STAT3Green MonkeylncRNA binding enablesIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeynuclear glucocorticoid receptor binding  ISONr3c1 (Rattus norvegicus)9068941 RGDPMID:20155810 and REF_RGD_ID:4892121
STAT3Green Monkeynuclear receptor activity enablesIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyprimary miRNA binding enablesIEAUniProtKB:P40763 and ensembl:ENSP00000264657150520179 EnsemblGO_REF:0000107
STAT3Green Monkeyprotein binding enablesISOPR:Q084819068941 PMID:11254359MGIPMID:11254359
STAT3Green Monkeyprotein binding enablesISOPR:Q06180 and PR:Q3ZN089068941 PMID:26026268MGIPMID:26026268
1 to 20 of 112 rows

RGD Manual Annotations


  

Imported Annotations - PID (archival)

1 to 9 of 9 rows
1 to 9 of 9 rows
PMID:30032202  



STAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,877,884 - 63,957,894 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,922,862 - 63,957,984 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,685,072 - 34,769,191 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,313,324 - 42,388,442 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,313,324 - 42,388,568 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,465,342 - 40,540,460 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,718,869 - 37,794,039 (-)NCBINCBI36Build 36hg18NCBI36
Build 341737,718,868 - 37,794,039NCBI
Celera1737,120,227 - 37,194,843 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,230,024 - 36,304,785 (-)NCBIHuRef
CHM1_11740,701,045 - 40,776,137 (-)NCBICHM1_1
T2T-CHM13v2.01743,169,811 - 43,244,652 (-)NCBIT2T-CHM13v2.0
Stat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,777,632 - 100,830,447 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,775,924 - 100,830,366 (-)EnsemblGRCm39 Ensembl
GRCm3811100,886,806 - 100,939,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,885,098 - 100,939,540 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711100,748,124 - 100,800,825 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,702,900 - 100,755,601 (-)NCBIMGSCv36mm8
MGSCv3611101,663,341 - 101,716,042 (-)NCBIMGSCv36mm8
Celera11112,235,347 - 112,235,602 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.82NCBI
Stat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,311,528 - 86,363,513 (-)NCBIGRCr8
mRatBN7.21085,811,206 - 85,863,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,811,218 - 85,863,057 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,847,511 - 90,899,338 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,326,207 - 90,377,980 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,719,368 - 85,771,150 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,790,401 - 88,842,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,790,408 - 88,842,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,584,605 - 88,638,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,821,078 - 89,872,970 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,835,448 - 89,887,340 (-)NCBI
Celera1084,529,054 - 84,580,831 (-)NCBICelera
RH 3.4 Map10837.0RGD
Cytogenetic Map10q31NCBI
Stat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,319,904 - 16,357,687 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,320,326 - 16,348,505 (-)NCBIChiLan1.0ChiLan1.0
STAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,594,115 - 22,671,720 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,486,658 - 24,561,894 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,928,689 - 15,003,644 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,152,358 - 15,227,084 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,152,358 - 15,227,067 (+)Ensemblpanpan1.1panPan2
STAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,539,660 - 20,614,631 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,539,697 - 20,612,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,001,678 - 20,076,249 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,258,611 - 21,334,353 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,258,632 - 21,334,351 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,044,250 - 20,119,519 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,309,625 - 20,386,466 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,413,942 - 20,489,100 (+)NCBIUU_Cfam_GSD_1.0
Stat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,877,467 - 19,955,950 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,117,290 - 17,178,402 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,119,189 - 17,178,402 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,407,233 - 20,472,992 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,407,316 - 20,471,091 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,709,840 - 20,775,669 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Stat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,648,080 - 1,681,200 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,648,235 - 1,680,788 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in STAT3
1680 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20


1 to 17 of 17 rows
RefSeq Transcripts XM_008012636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008012647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037993170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037993171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037993173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037993174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037993175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 17 of 17 rows

Ensembl Acc Id: ENSCSAT00000001245   ⟹   ENSCSAP00000014828
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1663,922,862 - 63,957,984 (+)Ensembl
RefSeq Acc Id: XM_008012636   ⟹   XP_008010827
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,884 - 63,956,019 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,078 - 34,769,191 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012637   ⟹   XP_008010828
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,884 - 63,956,019 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,077 - 34,767,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012638   ⟹   XP_008010829
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,884 - 63,956,019 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,078 - 34,767,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012639   ⟹   XP_008010830
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,884 - 63,957,894 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,077 - 34,767,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012640   ⟹   XP_008010831
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,884 - 63,956,019 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,078 - 34,767,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012642   ⟹   XP_008010833
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,884 - 63,956,019 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,078 - 34,769,191 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012645   ⟹   XP_008010836
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,877,896 - 63,957,894 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,072 - 34,767,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012646   ⟹   XP_008010837
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,916,931 - 63,956,019 (+)NCBI
Vero_WHO_p1.0NW_02366607734,725,225 - 34,767,030 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012647   ⟹   XP_008010838
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11663,878,077 - 63,957,894 (+)NCBI
Vero_WHO_p1.0NW_02366607734,685,198 - 34,767,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037993170   ⟹   XP_037849098
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607734,685,077 - 34,767,864 (+)NCBI
RefSeq Acc Id: XM_037993171   ⟹   XP_037849099
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607734,685,077 - 34,767,864 (+)NCBI
RefSeq Acc Id: XM_037993173   ⟹   XP_037849101
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607734,685,198 - 34,767,864 (+)NCBI
RefSeq Acc Id: XM_037993174   ⟹   XP_037849102
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607734,685,198 - 34,767,864 (+)NCBI
RefSeq Acc Id: XM_037993175   ⟹   XP_037849103
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607734,735,438 - 34,769,191 (+)NCBI
1 to 5 of 15 rows
1 to 5 of 15 rows
RefSeq Acc Id: XP_008010830   ⟸   XM_008012639
- Peptide Label: isoform X4
RefSeq Acc Id: XP_008010827   ⟸   XM_008012636
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008010831   ⟸   XM_008012640
- Peptide Label: isoform X5
RefSeq Acc Id: XP_008010829   ⟸   XM_008012638
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008010833   ⟸   XM_008012642
- Peptide Label: isoform X7



1 to 33 of 33 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000003215 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001245.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.532.10 UniProtKB/TrEMBL
  2.60.40.630 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  STAT transcription factor, all-alpha domain UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  STAT UniProtKB/TrEMBL
  STAT3_SH2 UniProtKB/TrEMBL
  STAT_linker UniProtKB/TrEMBL
  STAT_N_sf UniProtKB/TrEMBL
  STAT_TF_alpha UniProtKB/TrEMBL
  STAT_TF_coiled-coil UniProtKB/TrEMBL
  STAT_TF_DNA-bd UniProtKB/TrEMBL
  STAT_TF_DNA-bd_N UniProtKB/TrEMBL
  STAT_TF_prot_interaction UniProtKB/TrEMBL
NCBI Gene STAT3 ENTREZGENE
PANTHER PTHR11801 UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  STAT_alpha UniProtKB/TrEMBL
  STAT_bind UniProtKB/TrEMBL
  STAT_int UniProtKB/TrEMBL
  STAT_linker UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
SMART STAT_int UniProtKB/TrEMBL
Superfamily-SCOP SSF47655 UniProtKB/TrEMBL
  SSF48092 UniProtKB/TrEMBL
  SSF49417 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A0D9S1T9 ENTREZGENE, UniProtKB/TrEMBL
1 to 33 of 33 rows