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Gene: Fzd2 (frizzled class receptor 2) Rattus norvegicus
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Symbol: Fzd2
Name: frizzled class receptor 2
Description: Exhibits Wnt-activated receptor activity; identical protein binding activity; and protein heterodimerization activity. Involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; Wnt signaling pathway; and cellular response to vitamin D. Localizes to the plasma membrane. Biomarker of myocardial infarction. Orthologous to human FZD2 (frizzled class receptor 2); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, non-canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2-nitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 2; frizzled family receptor 2; frizzled homolog 2; frizzled homolog 2 (Drosophila); frizzled-2; Fz-10; fz-2; Fzd10; rFz2
Orthologs:
Homo sapiens (human) : FZD2 (frizzled class receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Fzd2 (frizzled class receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fzd2 (frizzled class receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FZD2 (frizzled class receptor 2)
Canis lupus familiaris (dog) : FZD2 (frizzled class receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fzd2 (frizzled class receptor 2)
Sus scrofa (pig) : FZD2 (frizzled class receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01090,550,147 - 90,552,057 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01090,343,133 - 90,345,043 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,709,222 - 91,711,132 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11091,723,591 - 91,725,502 (+)NCBI
Celera1086,269,032 - 86,270,942 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fzd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71012
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.