Bp342 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp342 (Blood pressure QTL 342) Rattus norvegicus

Symbol: Bp342
Name: Blood pressure QTL 342
RGD ID: 2313856
Trait: life span trait   (VT:0005372)    
Measurement Type: age at time of death   (CMO:0001193)    
LOD Score: 4.4
P Value: 1.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81087,807,758 - 96,620,484RGD_MAPPER_PIPELINE
mRatBN7.21087,307,617 - 96,121,100RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01090,296,897 - 99,492,409RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01090,085,487 - 99,184,250RGDRnor5.0
RGSC_v3.41091,455,572 - 100,633,982RGDRGSC3.4
Cross Type: intercross
Strains Crossed: SD-Tg(Ren2)27 LEW/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Ace is a candidate Gene for Bp342

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
LEW/NHsd  (IEA)
SD-Tg(Ren2)27  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic mapping of modifier loci affecting malignant hypertension in TGRmRen2 rats. Kantachuvesiri S, etal., Kidney Int 1999 Aug;56(2):414-20.
2. Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. Liu X, etal., J Biol Chem. 2009 Jun 5;284(23):15564-72. Epub 2009 Mar 23.
Related QTLs

Related QTL Description Reference
Bp343 interacts with RGD:619627


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3710Slc4a1solute carrier family 4 member 1 (Diego blood group)108780701087823274Rat
1590900Pno1-ps1partner of NOB1 homolog (S. cerevisiae), pseudogene 1108784617687847446Rat
735057Rundc3aRUN domain containing 3A108785274687861903Rat
1306193Slc25a39solute carrier family 25, member 39108786263087867626Rat
61983Grngranulin precursor108788783487893938Rat
1307966Fam171a2family with sequence similarity 171, member A2108789404987904213Rat
1596428Itga2bintegrin subunit alpha 2b108790869787926225Rat
1596463Gpatch8G patch domain containing 8108793217488012523Rat
402062964LOC134480882uncharacterized LOC134480882108793832887969053Rat
11482925LOC10835213960S ribosomal protein L36 pseudogene108802791388028262Rat
7648353LOC102550111uncharacterized LOC102550111108803856688052469Rat
71012Fzd2frizzled class receptor 2108806198888063898Rat
1591208Atp6v0c-ps1ATPase H+ transporting V0 subunit C, pseudogene 1108807409888084376Rat
1563746Meiocmeiosis specific with coiled-coil domain108812893988147833Rat
1311929Ccdc43coiled-coil domain containing 43108815067288162863Rat
41276998LOC120095185uncharacterized LOC120095185108819324888224985Rat
9450974LOC103693436uncharacterized LOC103693436108819424488207113Rat
7649594Dbf4bDBF4B-CDC7 kinase regulatory subunit108820991388219336Rat
1307515Adam11ADAM metallopeptidase domain 11108822418588242865Rat
628889Gjc1gap junction protein, gamma 1108826284088285646Rat
1306907Higd1bHIG1 hypoxia inducible domain family, member 1B108830228488304558Rat
1560116Eftud2elongation factor Tu GTP binding domain containing 2108830499288352229Rat
1562370Dnaaf19dynein axonemal assembly factor 19108834645388349853Rat
1307851FAM187Afamily with sequence similarity 187, member A108835095788352428Rat
2679Gfapglial fibrillary acidic protein108835298788361661Rat
1310360Kif18bkinesin family member 18B108837052088392388Rat
9420753Rpl22l4ribosomal protein L22 like 4108839253588398738Rat
1306039C1ql1complement C1q like 1108840221988409649Rat
1359211Dcakddephospho-CoA kinase domain containing108845782988489011Rat
628642Nmt1N-myristoyltransferase 1108848891888525496Rat
1310903Plcd3phospholipase C, delta 3108852680288548116Rat
1308404Acbd4acyl-CoA binding domain containing 4108854814688558588Rat
1559851Hexim1HEXIM P-TEFb complex subunit 1108856288988565001Rat
1311635Hexim2HEXIM P-TEFb complex subunit 2108857210288584856Rat
1311042Fmnl1formin-like 1108861529088643411Rat
2319718Efcab15EF-hand calcium binding domain 15108864345488653780Rat
1359156Spata32spermatogenesis associated 32108865330988664455Rat
41262638LOC120095296uncharacterized LOC120095296108866425388685161Rat
1310487Map3k14mitogen-activated protein kinase kinase kinase 14108866541788715669Rat
41159998LOC120095297uncharacterized LOC120095297108870508188725025Rat
735202Arhgap27Rho GTPase activating protein 27108878052788813275Rat
402391928LOC134480883uncharacterized LOC134480883108880518288810667Rat
1308010Plekhm1pleckstrin homology and RUN domain containing M1108881469988876570Rat
402016184LOC134480884uncharacterized LOC134480884108886258388900472Rat
1559753Lrrc37aleucine rich repeat containing 37A108889651788933472Rat
402083236LOC134480885uncharacterized LOC134480885108894429788959023Rat
735046Prp2l1proline rich protein 2-like 1108896229889040600Rat
9180709LOC103693460uncharacterized LOC103693460108903889989051784Rat
1306968Lyzl6lysozyme-like 6108904437589049210Rat
1589060Rprmlreprimo-like108906028089061284Rat
62079Gosr2golgi SNAP receptor complex member 2108908532389105665Rat
1564452Magmas-ps1mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1108910241189102931Rat
41172258LOC120095298uncharacterized LOC120095298108910574489113814Rat
1309574Wnt9bWnt family member 9B108913536289157065Rat
3972Wnt3Wnt family member 3108918022489224195Rat
621594NsfN-ethylmaleimide sensitive factor, vesicle fusing ATPase108922793789357383Rat
402217606LOC134480720uncharacterized LOC134480720108936485989367587Rat
621271Arf2ADP-ribosylation factor 2108936784389389644Rat
61276Crhr1corticotropin releasing hormone receptor 1108954019289583466Rat
1560562Sppl2csignal peptide peptidase like 2C108959526589597470Rat
69329Maptmicrotubule-associated protein tau108963861889736108Rat
6486111LOC100912629uncharacterized LOC100912629108964810489652237Rat
402194529LOC134480886uncharacterized LOC134480886108968542789694506Rat
402347559LOC134480887uncharacterized LOC134480887108971325689723753Rat
1311429Kansl1KAT8 regulatory NSL complex subunit 1108973763789868620Rat
41075489LOC120095423small nucleolar RNA SNORA21108976695389767080Rat
1304921Cdc27cell division cycle 27108990067689949770Rat
1591197Myl4myosin, light chain 4108994973389985308Rat
1591196Gstp1-ps2glutathione S-transferase pi 1, pseudogene 2108999898689999936Rat
628868Itgb3integrin subunit beta 3109000992790067787Rat
402265620LOC134480888uncharacterized LOC134480888109007280590085195Rat
1305423Efcab3EF-hand calcium binding domain 3109008449590577145Rat
11381204LOC108352141uncharacterized LOC108352141109038651090387544Rat
41249496LOC120095378U6 spliceosomal RNA109053332390533429Rat
1310240Mettl2methyltransferase like 2109059541190609234Rat
1590899Cactin-ps2cactin, spliceosome C complex subunit, pseudogene 2109064208790654295Rat
1310907Tlk2tousled-like kinase 2109064862390748427Rat
41034882LOC120095467U6atac minor spliceosomal RNA109072320890723300Rat
41101625Cycs-ps6cytochrome c, somatic, pseudogene 6109072722590727575Rat
1559436Mrc2mannose receptor, C type 2109076175190823055Rat
41318785LOC120095186uncharacterized LOC120095186109076215490777562Rat
41334181LOC120095187uncharacterized LOC120095187109078099090795872Rat
1311692Marchf10membrane associated ring-CH-type finger 10109083264790975700Rat
40927017LOC120095189uncharacterized LOC120095189109084316290866332Rat
11389364LOC108352144uncharacterized LOC108352144109091908590961733Rat
402161618LOC134480889uncharacterized LOC134480889109099313990997954Rat
40973775Trnav-aac25transfer RNA valine (anticodon AAC) 25109104806891048148Rat
1309285Tanc2tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2109105286091373291Rat
41337284LOC120095493U4 spliceosomal RNA109106464191064792Rat
41292971LOC120095191uncharacterized LOC120095191109115998191187275Rat
41135105LOC120095351U6 spliceosomal RNA109124964791249753Rat
9215295Snupn-ps1snurportin 1, pseudogene 1109131050391321238Rat
1310987Cyb561cytochrome b-561109137786691388548Rat
41378188LOC120095193uncharacterized LOC120095193109140717491421273Rat
2493Aceangiotensin I converting enzyme109141012991430246Rat
1561299Ace3angiotensin I converting enzyme (peptidyl-dipeptidase A) 3109143382891448854Rat
620304Kcnh6potassium voltage-gated channel subfamily H member 6109144902591471012Rat
1305140Dcaf7DDB1 and CUL4 associated factor 7109147390091496080Rat
1306784Taco1translational activator of cytochrome c oxidase I109150239591510299Rat
1304575Map3k3mitogen activated protein kinase kinase kinase 3109151997691588651Rat
1309967Limd2LIM domain containing 2109159007991592747Rat
727905StradaSTE20 related adaptor alpha109159464891623710Rat
1308813Ccdc47coiled-coil domain containing 47109163010191648626Rat
1304909Ddx42DEAD-box helicase 42109164871991680730Rat
1307110Ftsj3FtsJ RNA 2'-O-methyltransferase 3109168073591687475Rat
708376Psmc5proteasome 26S subunit, ATPase 5109168755391693487Rat
41071609LOC120095430small nucleolar RNA SNORA51109169001791690142Rat
69289Smarcd2SWI/SNF related BAF chromatin remodeling complex subunit D2109169354291702408Rat
69435Tcam1testicular cell adhesion molecule 1109170825891720269Rat
2686Gh1growth hormone 1109172788391729860Rat
620012Cd79bCD79b molecule109173913491742312Rat
3636Scn4asodium voltage-gated channel alpha subunit 4109174545991796452Rat
11498743LOC108352146uncharacterized LOC108352146109176813491777567Rat
1307288Prr29proline rich 29109180429191810213Rat
1359660Icam2intercellular adhesion molecule 2109180844991819319Rat
1559716Ern1endoplasmic reticulum to nucleus signaling 1109182666391920976Rat
41285482Rps10-ps6ribosomal protein S10, pseudogene 6109190255891903061Rat
7650056LOC102546698uncharacterized LOC102546698109193479291935296Rat
41075578Snord104small nucleolar RNA, C/D box 104109193507491935143Rat
41231368Snora50csmall nucleolar RNA, H/ACA box 50C109193533191935463Rat
1305112Tex2testis expressed 2109193639092046360Rat
41384166Trnap-agg83transfer RNA proline (anticodon AGG) 83109195231591952395Rat
61927Pecam1platelet and endothelial cell adhesion molecule 1109209026392152002Rat
620488Milr1mast cell immunoglobulin-like receptor 1109218400292205001Rat
1305128Polg2DNA polymerase gamma 2, accessory subunit109221230392222849Rat
619906Ddx5DEAD-box helicase 5109222439392231928Rat
9685093Mir3064microRNA 3064109222551892225584Rat
1309655Cep95centrosomal protein 95109223182992259813Rat
1310067Smurf2SMAD specific E3 ubiquitin protein ligase 2109226151692362185Rat
41360186Trnaa-agc91transfer RNA alanine (anticodon AGC) 91109228734792287427Rat
41351506LOC120095301survival of motor neuron-related-splicing factor 30-like109237025392371832Rat
11437264LOC108352149uncharacterized LOC108352149109239834792404717Rat
621419Kpna2karyopherin subunit alpha 2109243367892445841Rat
11508819Trnar-ccg2transfer RNA arginine (anticodon CCG) 2109245813092458202Rat
1565033C10h17orf58similar to human chromosome 17 open reading frame 58109247277992477330Rat
1307039Bptfbromodomain PHD finger transcription factor109248000792582485Rat
41304974LOC120095194uncharacterized LOC120095194109254929192554676Rat
41291495LOC120095432U11 spliceosomal RNA109259087592591008Rat
1584081Nol11nucleolar protein 11109262148292641394Rat
1562577Actb-ps10actin, beta, pseudogene 10109264273392643366Rat
1597047Pitpnc1phosphatidylinositol transfer protein, cytoplasmic 1109266326092928616Rat
41017670Snora80dsmall nucleolar RNA, H/ACA box 80D109268835292688484Rat
7727987Mea1-ps1male-enhanced antigen 1, pseudogene 1109273169692732348Rat
41186811LOC120095410small nucleolar RNA SNORA8109281435092814488Rat
1359290Rpl17-ps16ribosomal protein L17, pseudogene 16109287339292874025Rat
1582971Rps23-ps9ribosomal protein S23, pseudogene 9109293393092934447Rat
1359305Psmd12proteasome 26S subunit, non-ATPase 12109293795792956601Rat
1307049Helzhelicase with zinc finger109297903993144868Rat
2249Cacng1calcium voltage-gated channel auxiliary subunit gamma 1109315255893165246Rat
41352320LOC120095197uncharacterized LOC120095197109316112493184930Rat
628804Cacng4calcium voltage-gated channel auxiliary subunit gamma 4109318341093245470Rat
402319976LOC134480890uncharacterized LOC134480890109318963593218010Rat
11397811LOC108352150uncharacterized LOC108352150109321845793229638Rat
11411384LOC108352151uncharacterized LOC108352151109326348893284347Rat
628805Cacng5calcium voltage-gated channel auxiliary subunit gamma 5109332714293369244Rat
3395Prkcaprotein kinase C, alpha109338899193787617Rat
1310625Apohapolipoprotein H109384199293855897Rat
1564168Cep112centrosomal protein 112109386563094332679Rat
402001926LOC134480891uncharacterized LOC134480891109401874194020270Rat
40973555LOC120095198uncharacterized LOC120095198109432488694331569Rat
41189455LOC120095199uncharacterized LOC120095199109436787994386419Rat
69259Axin2axin 2109439337994426579Rat
11444070LOC108352227uncharacterized LOC108352227109443535394438298Rat
40994897LOC120095200uncharacterized LOC120095200109448532594520945Rat
7698326LOC102550112uncharacterized LOC102550112109451628894537789Rat
7529341LOC102550334uncharacterized LOC102550334109454260794601766Rat
41387346LOC120095201uncharacterized LOC120095201109460839194618833Rat
41147803LOC120095202uncharacterized LOC120095202109463403894647218Rat
7551922LOC102550454uncharacterized LOC102550454109466681894672717Rat
1597401Rpl10a-ps5ribosomal protein L10A, pseudogene 5109467383394674495Rat
1565459Mifl4macrophage migration inhibitory factor like 4109468869194696405Rat
3572Rgs9regulator of G-protein signaling 9109469655694770387Rat
7579672LOC102550782uncharacterized LOC102550782109473921194744345Rat
41120726LOC120095203uncharacterized LOC120095203109478869194796489Rat
7625474LOC102550846uncharacterized LOC102550846109481638694817681Rat
402006339LOC134480892uncharacterized LOC134480892109482655694836846Rat
1310221Gna13G protein subunit alpha 13109483727194870290Rat
1304846Amz2archaelysin family metallopeptidase 2109490105394911629Rat
1306571Arsgarylsulfatase G109491209495063021Rat
735117Slc16a6solute carrier family 16, member 6109492388894946990Rat
402227108LOC1344808935E5 antigen-like109494450094954086Rat
1307754Wipi1WD repeat domain, phosphoinositide interacting 1109504245195079679Rat
6488368LOC100912202uncharacterized LOC100912202109511684395120611Rat
3391Prkar1aprotein kinase cAMP-dependent type I regulatory subunit alpha109512053795139028Rat
1306364Fam20aFAM20A, golgi associated secretory pathway pseudokinase109513679995197176Rat
401997979LOC134480894uncharacterized LOC134480894109516341095174673Rat
15595781700012B07RklRIKEN cDNA 1700012B07 gene like109527103495304337Rat
7651542Rpl23a-ps1ribosomal protein L23a, pseudogene 1109541583995416870Rat
1307069Abca8ATP binding cassette subfamily A member 8109541698495490647Rat
1307333Abca8aATP-binding cassette, subfamily A (ABC1), member 8a109550179895571770Rat
1305931Abca9ATP binding cassette subfamily A member 9109557707995638706Rat
1308998Abca6ATP binding cassette subfamily A member 6109564202695711535Rat
628661Abca5ATP binding cassette subfamily A member 5109573961095808633Rat
620666Map2k6mitogen-activated protein kinase kinase 6109587274795987747Rat
7693387LOC102551705uncharacterized LOC102551705109601288196027047Rat
11381410LOC108352228uncharacterized LOC108352228109626365196277412Rat
61824Kcnj16potassium inwardly-rectifying channel, subfamily J, member 16109648932996520745Rat
41147005LOC120095205uncharacterized LOC120095205109650686296517857Rat
40991355LOC120095206uncharacterized LOC120095206109655363196560187Rat
61968Kcnj2potassium inwardly-rectifying channel, subfamily J, member 2109656022596570788Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10466D10Mit1194109141768591417879Ratregion
10467D10Wox18173109141769691417869Ratregion
10926D10Wox21130108963582289635952Ratregion
11169D10Mgh21140108903917589039315Ratregion
34100D10Mgh3153109609974996099902Ratregion
34485D10Mgh4104109286902592869129Ratregion
11308D10Wox20111108780775887807869Ratregion
36297D10Rat52144109308475493084898Ratregion
35256D10Rat11191109662029396620484Ratregion
36958D10Rat9140109560453795604677Ratregion
37150D10Rat204221109090424590904466Ratregion
36624D10Rat13283109319859093198873Ratregion
34813D10Rat16164109360796793608131Ratregion
34896D10Rat17184109112727091127454Ratregion
35627D10Rat12159109522434495224503Ratregion
39928D10Rat189195109372338193723576Ratregion
40572D10Rat203132109260843792608569Ratregion
39136D10Rat74213109500506795005280Ratregion
39140D10Rat84135108903918089039315Ratregion
39302D10Rat120251108863246088632711Ratregion
39306D10Rat122212108864948488649696Ratregion
39410D10Rat140187109003487990035066Ratregion
41932D10Arb13269108780772587807994Ratregion
42259D10Rat54338109217585192176189Ratregion
42932D10Rat234255109083571890835973Ratregion
42933D10Rat202148109177521891775366Ratregion
42934D10Rat233214109516419695164410Ratregion
40794D10Rat141236108890050188900737Ratregion
44815D10Got131205108807820688078411Ratregion
44819D10Got135221108975834089758561Ratregion
44833D10Got149205109527450695274711Ratregion
59969D10Got133267108961598089616247Ratregion
59972D10Got151287109534514095345427Ratregion
59976D10Got163106109447684194476947Ratregion
66502D10Mco69236109595341295953648Ratregion
66524D10Mco74586109270821592708801Ratregion
66565D10Mco7316109524058895240904Ratregion
66715D10Mco15212109449528094495492Ratregion
67318D10Arb12241109062853790628778Ratregion
1578868D10Chm159243109335312893353371Ratregion
1630061D10Got216123108983627489836397Ratregion
1578874D10Chm155161109605161496051775Ratregion
1578920D10Chm55215109487131494871529Ratregion
1578923D10Chm235258109435260194352859Ratregion
1578932D10Chm54300109492129694921596Ratregion
1578975D10Chm240251109486878494869035Ratregion
1578980D10Chm12205109348112093481325Ratregion
1578981D10Chm254273109582158995821862Ratregion
1578983D10Chm156154109643242296432576Ratregion
1579130D10Chm154197109546460595464802Ratregion
1579168D10Chm260251109560653095606781Ratregion
5037091RH46167246109550747295507718Ratregion
5027815RH94851240109339411093394350Ratregion
5056199RH144240337108896264188962978Ratregion
5054863RH143468170109083557090835740Ratregion
5052665RH142195167108836089488361061Ratregion
5054485RH143251195109248007892480273Ratregion
5043736RH130197195108793217487932369Ratregion
5045862RH131422160109511989295120052Ratregion
5039412RH127691184109209042392090607Ratregion
5040806RH128494251108852684688527097Ratregion
5072654RH136975269109169320991693478Ratregion
5078804RH140561620108786016687860786Ratregion
5071892RH135345203108973244089732643Ratregion
5069488AU046465148109280573592805883Ratregion
5060334AW531488188108954392389544111Ratregion
5061084AW532191707108965128089651987Ratregion
5086923BQ191940207109531556595315772Ratregion
5087291BQ208647170109266606192666231Ratregion
5090823AU049984149109081147690811625Ratregion
5090357AU049703129109464136394641492Ratregion
5085870AA866270196109193655891936754Ratregion
5503136NSF-1654108927522889275882Ratregion
5506019Crhr1429108957639489576823Ratregion
5507111UniSTS:224586165108973337489733539Ratregion
5499625MARC_4113-4114:991938380:3681109168755791688238Ratregion
5502018MARC_23993-23994:1029524382:1796108830680388307599Ratregion
10402890D10Chm276238109586005095860288Ratregion
10402916D10Chm289153109207052392070676Ratregion
Position Markers

Flank 1: (D10Wox20)
Rat AssemblyChrPosition (strand)Source
GRCr81087,807,758 - 87,807,869 (+)Marker Load Pipeline
mRatBN7.21087,307,617 - 87,307,728 (+)MAPPER
Rnor_6.01090,296,897 - 90,297,007NCBI
Rnor_5.01090,085,487 - 90,085,597UniSTS
RGSC_v3.41091,455,572 - 91,455,683RGD
RGSC_v3.41091,455,573 - 91,455,683UniSTS
RGSC_v3.11091,469,942 - 91,470,053RGD
Celera1086,019,596 - 86,019,706UniSTS
RH 3.4 Map10880.59UniSTS
RH 3.4 Map10880.59RGD
RH 2.0 Map101017.0RGD
Cytogenetic Map10q32UniSTS
Peak: (Ace)
Rat AssemblyChrPosition (strand)Source
GRCr81091,410,129 - 91,430,246 (+)NCBI
mRatBN7.21090,910,316 - 90,930,437 (+)NCBI
mRatBN7.2 Ensembl1090,910,316 - 90,931,131 (+)Ensembl
UTH_Rnor_SHR_Utx1095,964,627 - 95,984,783 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01095,427,801 - 95,447,951 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01090,839,016 - 90,859,102 (+)NCBI
Rnor_6.01094,170,766 - 94,213,831 (+)NCBI
Rnor_6.0 Ensembl1094,170,766 - 94,187,822 (+)Ensembl
Rnor_5.01093,922,062 - 93,965,127 (+)NCBI
RGSC_v3.41095,361,338 - 95,381,455 (+)NCBI
Celera1089,588,544 - 89,608,666 (+)NCBI
Cytogenetic Map10q32.1NCBI
Flank 2: (D10Rat11)
Rat AssemblyChrPosition (strand)Source
GRCr81096,620,293 - 96,620,484 (+)Marker Load Pipeline
mRatBN7.21096,120,911 - 96,121,100 (+)MAPPER
Rnor_6.01099,492,217 - 99,492,409NCBI
Rnor_5.01099,184,058 - 99,184,250UniSTS
RGSC_v3.410100,633,654 - 100,633,848UniSTS
RGSC_v3.410100,633,512 - 100,633,982RGD
RGSC_v3.110100,648,024 - 100,648,218RGD
Celera1094,766,403 - 94,766,596UniSTS
RH 3.4 Map101084.8RGD
RH 3.4 Map101084.8UniSTS
RH 2.0 Map101218.2RGD
SHRSP x BN Map1077.15RGD
FHH x ACI Map1082.4RGD


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093723381107556066Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108101207791729860Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
631558Bp137Blood pressure QTL 1370.013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)109522434497335592Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)109090424595604677Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108306123692869129Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)1079272424102982300Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395464802Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
2313856Bp342Blood pressure QTL 3424.40.0001life span trait (VT:0005372)age at time of death (CMO:0001193)108780775896620484Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087807758107713808Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106724133498502431Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)109112727095604677Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1091127270107556066Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)107369533997272278Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1081012077101828297Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)9090424595604677Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)9090424595604677Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)109090424595604677Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107304965694495280Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)109090424595604677Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)109090424595604677Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1089039175107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)108890050196620484Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1558652Bw57Body weight QTL 574.20.0008body mass (VT:0001259)body weight (CMO:0000012)108982706891430246Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108450348796432422Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395604677Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108450348796432422Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091727883107713808Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene 100310884

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 252 males 619627
qtl_general measurement method: two F1 populations were produced by SD-Tg(Ren2)27 males and F344 and LEW females; animals which had no symptoms of MH (polyuria, weight loss lethargy, hemiparesis, piloerection, seizure and lethality) by 120 days of age were marked as survived and the age of death of the others was noted 619627
qtl_general all males from F344 females developed terminal MH from 50-70 days; all males from LEW females survived 120 days without any symptoms 619627
qtl_general locus responsible for the reduction of life span by 7.3+-1.6 days and increased the probability of MH by 4.2 fold 619627
qtl_general higher ACE activity was noticed in F344 progeny as compard to LEW progeny 619627