Gene: Ern1 (endoplasmic reticulum to nucleus signaling 1) Rattus norvegicus
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Symbol: Ern1
Name: endoplasmic reticulum to nucleus signaling 1
Description: ENCODES a protein that exhibits Hsp90 protein binding; ADP binding (ortholog); ATP binding (ortholog); INVOLVED IN cellular response to manganese ion; activation of JUN kinase activity (ortholog); cell cycle arrest (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Alzheimer's disease pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH epilepsy (ortholog); hyperkalemic periodic paralysis (ortholog); Smith-Magenis syndrome (ortholog); FOUND IN AIP1-IRE1 complex (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 1,4-dithiothreitol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methyl-6-(phenylethynyl)pyridine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endoplasmic reticulum (ER) to nucleus signalling 1; LOC498013; RGD1559716; serine/threonine-protein kinase/endoribonuclease IRE1; similar to protein kinase/endoribonuclease(IRE1) alpha
Orthologs:
Homo sapiens (human) : ERN1 (endoplasmic reticulum to nucleus signaling 1)  HGNC  Alliance
Mus musculus (house mouse) : Ern1 (endoplasmic reticulum (ER) to nucleus signalling 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Canis lupus familiaris (dog) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ern1 (endoplasmic reticulum to nucleus signaling 1)
Sus scrofa (pig) : ERN1 (endoplasmic reticulum to nucleus signaling 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01094,588,555 - 94,682,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,336,640 - 94,429,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,794,488 - 95,855,895 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1090,003,932 - 90,064,578 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ern1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1559716
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE