(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ERN1 mRNA] CTD PMID:31150632 (S)-nicotine multiple interactions ISO RGD:1558600 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 (Z)-3-butylidenephthalide increases expression ISO RGD:1605125 6480464 butylidenephthalide results in increased expression of ERN1 protein CTD PMID:23770345 1,2-dichloroethane decreases expression ISO RGD:1558600 6480464 ethylene dichloride results in decreased expression of ERN1 mRNA CTD PMID:28973639 1,2-dichloroethane increases expression ISO RGD:1558600 6480464 ethylene dichloride results in increased expression of ERN1 mRNA CTD PMID:28960355 1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:1558600 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 , PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:1605125 6480464 TXN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:1558600 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-naphthyl isothiocyanate multiple interactions ISO RGD:1605125 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of ERN1 mRNA CTD PMID:27344345 15-acetyldeoxynivalenol decreases expression ISO RGD:1605125 6480464 15-acetyldeoxynivalenol results in decreased expression of ERN1 mRNA CTD PMID:20682335 17beta-estradiol increases expression ISO RGD:1605125 6480464 Estradiol results in increased expression of ERN1 mRNA CTD PMID:23373633 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1605125 6480464 Dihydrotestosterone results in increased expression of ERN1 mRNA CTD PMID:29581250 1H-pyrazole increases expression ISO RGD:1558600 6480464 pyrazole results in increased expression of ERN1 mRNA CTD PMID:17945193 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1605125 6480464 ERN1 protein affects the reaction [2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether affects response to substance ISO RGD:1605125 6480464 ERN1 protein affects the susceptibility to 2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether increases phosphorylation ISO RGD:1558600 6480464 2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1558600 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1605125 6480464 2 more ... CTD PMID:22543052 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ERN1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ERN1 mRNA CTD PMID:18796159 , PMID:27136898 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1558600 6480464 Tetrachlorodibenzodioxin results in decreased expression of ERN1 mRNA CTD PMID:18796159 , PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of ERN1 protein CTD PMID:24932542 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1558600 6480464 Tetrachlorodibenzodioxin affects the expression of ERN1 mRNA CTD PMID:21570461 2,4-dichlorophenol increases expression ISO RGD:1558600 6480464 2, 4-dichlorophenol results in increased expression of ERN1 mRNA CTD PMID:25160872 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:1558600 6480464 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA], ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 2-hydroxypropanoic acid decreases expression ISO RGD:1605125 6480464 Lactic Acid results in decreased expression of ERN1 mRNA CTD PMID:30851411 2-methyl-6-(phenylethynyl)pyridine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1558600 6480464 tetrabromobisphenol A results in increased expression of ERN1 mRNA CTD PMID:25172293 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:1558600 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of ERN1 mRNA CTD PMID:26251327 3-acetyldeoxynivalenol increases expression ISO RGD:1605125 6480464 3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA CTD PMID:20682335 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of ERN1 mRNA CTD PMID:28522335 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of ERN1 mRNA CTD PMID:19162173 4-hydroxynon-2-enal decreases expression ISO RGD:1558600 6480464 4-hydroxy-2-nonenal results in decreased expression of ERN1 mRNA CTD PMID:19191707 4-phenylbutyric acid multiple interactions ISO RGD:1605125 6480464 4-phenylbutyric acid inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein] more ... CTD PMID:23885834 more ... 4-phenylbutyric acid decreases expression ISO RGD:1605125 6480464 4-phenylbutyric acid results in decreased expression of ERN1 protein CTD PMID:29444456 , PMID:30796460 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] CTD PMID:20399799 ADP multiple interactions ISO RGD:1558600 6480464 Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein] CTD PMID:25164867 ADP decreases activity ISO RGD:1558600 6480464 Adenosine Diphosphate results in decreased activity of ERN1 protein CTD PMID:25164867 aflatoxin B1 increases expression ISO RGD:1558600 6480464 Aflatoxin B1 results in increased expression of ERN1 mRNA CTD PMID:19770486 aldehydo-D-glucosamine multiple interactions ISO RGD:1558600 6480464 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA], ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 aldehydo-D-glucose increases phosphorylation ISO RGD:1605125 6480464 Glucose deficiency results in increased phosphorylation of ERN1 protein CTD PMID:31022492 aldehydo-D-glucose multiple interactions ISO RGD:1605125 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein] CTD PMID:31022492 all-trans-retinoic acid increases expression ISO RGD:1558600 6480464 Tretinoin results in increased expression of ERN1 mRNA, Tretinoin results in increased expression of ERN1 protein CTD PMID:22498432 all-trans-retinoic acid increases expression ISO RGD:1605125 6480464 Tretinoin results in increased expression of ERN1 mRNA CTD PMID:23724009 amiloride multiple interactions ISO RGD:1558600 6480464 Amiloride inhibits the reaction [Tunicamycin results in increased phosphorylation of and results in increased activity of ERN1 protein] CTD PMID:20015086 amiodarone increases phosphorylation ISO RGD:1558600 6480464 Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:28962527 amosite asbestos increases expression EXP 6480464 Asbestos, Amosite results in increased expression of ERN1 protein CTD PMID:23885834 amosite asbestos multiple interactions ISO RGD:1605125 6480464 4-phenylbutyric acid inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein] more ... CTD PMID:23885834 amosite asbestos increases expression ISO RGD:1605125 6480464 Asbestos, Amosite results in increased expression of ERN1 mRNA, Asbestos, Amosite results in increased expression of ERN1 protein CTD PMID:23885834 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1605125 6480464 pyrazolanthrone inhibits the reaction [dihydrocapsaicin results in increased expression of ERN1 protein] CTD PMID:19139269 apigenin multiple interactions ISO RGD:1558600 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein], Apigenin inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] CTD PMID:20493918 arsenous acid multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] CTD PMID:30660605 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of ERN1 protein CTD PMID:30660605 arsenous acid increases expression ISO RGD:1605125 6480464 Arsenic Trioxide results in increased expression of ERN1 mRNA, Arsenic Trioxide results in increased expression of ERN1 protein CTD PMID:17963750 more ... atrazine increases expression ISO RGD:1605125 6480464 Atrazine results in increased expression of ERN1 mRNA CTD PMID:22378314 Azaspiracid decreases expression ISO RGD:1605125 6480464 azaspiracid results in decreased expression of ERN1 mRNA CTD PMID:28939011 baicalin multiple interactions ISO RGD:1558600 6480464 baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 benomyl increases expression ISO RGD:1605125 6480464 Benomyl results in increased expression of ERN1 protein CTD PMID:27784618 benomyl multiple interactions ISO RGD:1605125 6480464 Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein], MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ERN1 protein] CTD PMID:27784618 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1605125 6480464 7 more ... CTD PMID:19150397 beta-D-glucosamine multiple interactions ISO RGD:1558600 6480464 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA], ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 bicuculline multiple interactions ISO RGD:1558600 6480464 [Bicuculline co-treated with Ethanol] results in increased phosphorylation of ERN1 protein CTD PMID:29044621 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ERN1 mRNA CTD PMID:25181051 bisphenol A affects expression ISO RGD:1605125 6480464 bisphenol A affects the expression of ERN1 mRNA CTD PMID:30903817 bisphenol A increases methylation ISO RGD:1558600 6480464 bisphenol A results in increased methylation of ERN1 promoter CTD PMID:27312807 bortezomib multiple interactions ISO RGD:1605125 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of ERN1 mRNA CTD PMID:25522274 bortezomib decreases response to substance ISO RGD:1605125 6480464 ERN1 results in decreased susceptibility to Bortezomib CTD PMID:16357177 brefeldin A multiple interactions ISO RGD:1558600 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein] CTD PMID:20493918 brefeldin A increases phosphorylation ISO RGD:1558600 6480464 Brefeldin A results in increased phosphorylation of ERN1 protein CTD PMID:20493918 cadmium atom increases expression ISO RGD:1605125 6480464 Cadmium results in increased expression of ERN1 mRNA CTD PMID:21120746 cadmium atom multiple interactions ISO RGD:1558600 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein, Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein] CTD PMID:29373603 cadmium dichloride multiple interactions ISO RGD:1558600 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein, Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein] CTD PMID:29373603 cadmium dichloride increases expression ISO RGD:1605125 6480464 Cadmium Chloride results in increased expression of ERN1 mRNA, Cadmium Chloride results in increased expression of ERN1 protein CTD PMID:29444456 , PMID:30796460 cadmium dichloride multiple interactions ISO RGD:1605125 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] more ... CTD PMID:29444456 , PMID:30796460 caffeine multiple interactions ISO RGD:1558600 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Calcimycin increases expression ISO RGD:1605125 6480464 Calcimycin results in increased expression of ERN1 protein CTD PMID:19139269 Candesartan cilexetil decreases expression EXP 6480464 candesartan cilexetil results in decreased expression of ERN1 protein CTD PMID:22120037 cantharidin increases expression ISO RGD:1605125 6480464 Cantharidin results in increased expression of ERN1 protein CTD PMID:27113412 capsaicin increases expression ISO RGD:1605125 6480464 Capsaicin results in increased expression of ERN1 protein CTD PMID:19139269 , PMID:19699254 carbamazepine affects expression ISO RGD:1605125 6480464 Carbamazepine affects the expression of ERN1 mRNA CTD PMID:24752500 carbon nanotube increases phosphorylation ISO RGD:1558600 6480464 Nanotubes, Carbon results in increased phosphorylation of ERN1 protein CTD PMID:24929217 cerulenin multiple interactions ISO RGD:1605125 6480464 Cerulenin affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] CTD PMID:17283163 ceruletide multiple interactions EXP 6480464 Dietary Fats promotes the reaction [Ceruletide results in increased expression of ERN1 mRNA] more ... CTD PMID:26873426 ceruletide increases expression EXP 6480464 Ceruletide results in increased expression of ERN1 mRNA, Ceruletide results in increased expression of ERN1 protein CTD PMID:26873426 chloroacetic acid increases phosphorylation ISO RGD:1558600 6480464 chloroacetic acid results in increased phosphorylation of ERN1 protein CTD PMID:25451595 chloroacetic acid multiple interactions ISO RGD:1558600 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of ERN1 protein] CTD PMID:25451595 chloropicrin increases expression ISO RGD:1605125 6480464 chloropicrin results in increased expression of ERN1 protein CTD PMID:22516760 choline multiple interactions ISO RGD:1558600 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene CTD PMID:20938992 chrysophanol increases expression ISO RGD:1605125 6480464 chrysophanic acid results in increased expression of ERN1 protein CTD PMID:30300626 cisplatin increases expression ISO RGD:1605125 6480464 Cisplatin results in increased expression of ERN1 mRNA CTD PMID:27594783 cobalt dichloride increases expression ISO RGD:1605125 6480464 cobaltous chloride results in increased expression of ERN1 mRNA CTD PMID:19320972 cocaine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein] more ... CTD PMID:17303341 cocaine increases expression EXP 6480464 Cocaine results in increased expression of ERN1 protein CTD PMID:17303341 copper(II) sulfate increases expression ISO RGD:1605125 6480464 Copper Sulfate results in increased expression of ERN1 mRNA CTD PMID:19549813 curcumin decreases expression ISO RGD:1605125 6480464 Curcumin results in decreased expression of ERN1 mRNA CTD PMID:17999991 curcumin increases expression ISO RGD:1605125 6480464 Curcumin results in increased expression of ERN1 mRNA CTD PMID:29723631 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of ERN1 protein CTD PMID:20136702 cyclosporin A increases expression ISO RGD:1558600 6480464 Cyclosporine results in increased expression of ERN1 protein CTD PMID:27585667 cyclosporin A multiple interactions ISO RGD:1558600 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of ERN1 protein], TLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of ERN1 protein] CTD PMID:27585667 cyclosporin A increases expression ISO RGD:1605125 6480464 Cyclosporine results in increased expression of ERN1 mRNA CTD PMID:25562108 cyclosporin A increases phosphorylation ISO RGD:1558600 6480464 Cyclosporine results in increased phosphorylation of ERN1 protein CTD PMID:23958496 cyclosporin A affects localization ISO RGD:1558600 6480464 Cyclosporine affects the localization of ERN1 protein CTD PMID:23958496 cyclosporin A multiple interactions EXP 6480464 Melatonin promotes the reaction [Cyclosporine results in increased expression of ERN1 protein] CTD PMID:20136702 D-glucose increases phosphorylation ISO RGD:1605125 6480464 Glucose deficiency results in increased phosphorylation of ERN1 protein CTD PMID:31022492 D-glucose multiple interactions ISO RGD:1605125 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein] CTD PMID:31022492 Deguelin decreases expression ISO RGD:1605125 6480464 deguelin results in decreased expression of ERN1 protein CTD PMID:25322282 demethoxycurcumin multiple interactions ISO RGD:1605125 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] CTD PMID:26264395 deoxynivalenol increases expression ISO RGD:1558600 6480464 deoxynivalenol results in increased expression of ERN1 protein CTD PMID:19336499 deoxynivalenol decreases expression ISO RGD:1605125 6480464 deoxynivalenol results in decreased expression of ERN1 mRNA CTD PMID:20682335 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of ERN1 protein CTD PMID:30660605 diarsenic trioxide increases expression ISO RGD:1605125 6480464 Arsenic Trioxide results in increased expression of ERN1 mRNA, Arsenic Trioxide results in increased expression of ERN1 protein CTD PMID:17963750 more ... diarsenic trioxide multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] CTD PMID:30660605 diclofenac affects expression ISO RGD:1605125 6480464 Diclofenac affects the expression of ERN1 mRNA CTD PMID:24752500 dihydrocapsaicin multiple interactions ISO RGD:1605125 6480464 pyrazolanthrone inhibits the reaction [dihydrocapsaicin results in increased expression of ERN1 protein] CTD PMID:19139269 dihydrocapsaicin increases expression ISO RGD:1605125 6480464 dihydrocapsaicin results in increased expression of ERN1 protein CTD PMID:19139269 dinophysistoxin 1 increases expression ISO RGD:1605125 6480464 dinophysistoxin 1 results in increased expression of ERN1 mRNA CTD PMID:28939011 edaravone increases expression EXP 6480464 Edaravone results in increased expression of ERN1 mRNA CTD PMID:19558813 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of ERN1 mRNA CTD PMID:29391264 epoxomicin multiple interactions ISO RGD:1558600 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 ethanol increases expression ISO RGD:1558600 6480464 Ethanol results in increased expression of ERN1 mRNA, Ethanol results in increased expression of ERN1 protein CTD PMID:18377926 , PMID:30319688 ethanol increases phosphorylation ISO RGD:1558600 6480464 Ethanol results in increased phosphorylation of ERN1 protein CTD PMID:29044621 ethanol multiple interactions ISO RGD:1558600 6480464 [Bicuculline co-treated with Ethanol] results in increased phosphorylation of ERN1 protein more ... CTD PMID:29044621 ethanol multiple interactions ISO RGD:1605125 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of ERN1 protein modified form] CTD PMID:24224909 ethanol increases expression ISO RGD:1605125 6480464 Ethanol results in increased expression of ERN1 protein modified form CTD PMID:24224909 ethanol decreases phosphorylation ISO RGD:1558600 6480464 Ethanol results in decreased phosphorylation of ERN1 protein CTD PMID:28119953 ferric oxide multiple interactions ISO RGD:1558600 6480464 ferric oxide analog results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:25086211 fluoranthene multiple interactions ISO RGD:1558600 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of ERN1 mRNA CTD PMID:28329830 folic acid multiple interactions ISO RGD:1558600 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene CTD PMID:20938992 formaldehyde increases phosphorylation ISO RGD:1605125 6480464 Formaldehyde results in increased phosphorylation of ERN1 protein CTD PMID:24140967 formaldehyde increases expression ISO RGD:1605125 6480464 Formaldehyde results in increased expression of ERN1 mRNA CTD PMID:17938736 more ... gadolinium trichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein] CTD PMID:21198628 gadolinium trichloride increases expression EXP 6480464 gadolinium chloride results in increased expression of ERN1 protein CTD PMID:21198628 gamma-aminobutyric acid multiple interactions ISO RGD:1558600 6480464 gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased phosphorylation of ERN1 protein] CTD PMID:29044621 geraniol multiple interactions ISO RGD:1605125 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] CTD PMID:30141137 glucose multiple interactions ISO RGD:1605125 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein] CTD PMID:31022492 glucose increases phosphorylation ISO RGD:1605125 6480464 Glucose deficiency results in increased phosphorylation of ERN1 protein CTD PMID:31022492 glycyrrhetinate multiple interactions ISO RGD:1605125 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 glycyrrhetinic acid multiple interactions ISO RGD:1605125 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 gold atom increases phosphorylation ISO RGD:1605125 6480464 Gold analog results in increased phosphorylation of ERN1 protein CTD PMID:26551149 gold(0) increases phosphorylation ISO RGD:1605125 6480464 Gold analog results in increased phosphorylation of ERN1 protein CTD PMID:26551149 Guanabenz multiple interactions EXP 6480464 Guanabenz inhibits the reaction [Tunicamycin results in increased phosphorylation of ERN1 protein] CTD PMID:24892553 hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 mRNA more ... CTD PMID:26873426 hexadecanoic acid multiple interactions ISO RGD:1558600 6480464 7 more ... CTD PMID:29031535 , PMID:29414781 hexadecanoic acid increases phosphorylation ISO RGD:1558600 6480464 Palmitic Acid results in increased phosphorylation of ERN1 protein CTD PMID:29031535 , PMID:29414781 homocysteine decreases phosphorylation ISO RGD:1605125 6480464 Homocysteine results in decreased phosphorylation of ERN1 protein CTD PMID:22964297 hydrogen peroxide multiple interactions ISO RGD:1605125 6480464 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ERN1 protein] CTD PMID:23885834 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of ERN1 protein CTD PMID:23885834 hydrogen peroxide increases expression ISO RGD:1605125 6480464 Hydrogen Peroxide results in increased expression of ERN1 protein CTD PMID:23885834 L-1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 L-methionine multiple interactions ISO RGD:1558600 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene CTD PMID:20938992 lead diacetate increases expression ISO RGD:1558600 6480464 lead acetate results in increased expression of ERN1 mRNA CTD PMID:21829687 lead diacetate multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of ERN1 protein] CTD PMID:25088297 lead diacetate increases phosphorylation EXP 6480464 lead acetate results in increased phosphorylation of ERN1 protein CTD PMID:25088297 leflunomide increases expression ISO RGD:1605125 6480464 leflunomide results in increased expression of ERN1 mRNA CTD PMID:28988120 manganese(II) chloride multiple interactions EXP 6480464 SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein] CTD PMID:23934647 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of ERN1 protein CTD PMID:23934647 , PMID:25732873 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form], Melatonin promotes the reaction [Cyclosporine results in increased expression of ERN1 protein] CTD PMID:20136702 , PMID:28070110 metacetamol decreases expression ISO RGD:1558600 6480464 3-hydroxyacetanilide results in decreased expression of ERN1 mRNA CTD PMID:18544908 methamphetamine multiple interactions ISO RGD:1605125 6480464 ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein] more ... CTD PMID:27323860 methamphetamine multiple interactions EXP 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form] CTD PMID:28070110 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of ERN1 protein modified form CTD PMID:28070110 methamphetamine increases phosphorylation ISO RGD:1605125 6480464 Methamphetamine results in increased phosphorylation of ERN1 protein CTD PMID:27323860 methamphetamine increases expression ISO RGD:1558600 6480464 Methamphetamine results in increased expression of ERN1 protein CTD PMID:27323860 methotrexate affects expression ISO RGD:1558600 6480464 Methotrexate affects the expression of ERN1 mRNA CTD PMID:18502557 methylmercury chloride multiple interactions ISO RGD:1558600 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form], AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form] CTD PMID:31330229 methylmercury chloride increases expression ISO RGD:1558600 6480464 methylmercuric chloride results in increased expression of ERN1 protein modified form CTD PMID:31330229 methyltestosterone multiple interactions ISO RGD:1605125 6480464 [Methyltestosterone co-treated with Cholic Acids] affects the expression of ERN1 mRNA CTD PMID:27344345 minocycline increases phosphorylation EXP 6480464 Minocycline results in increased phosphorylation of ERN1 protein CTD PMID:22245251 MK-2206 multiple interactions ISO RGD:1605125 6480464 MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 morusin increases expression ISO RGD:1605125 6480464 morusin results in increased expression of ERN1 protein CTD PMID:29421517 muscimol multiple interactions ISO RGD:1558600 6480464 Muscimol inhibits the reaction [Ethanol results in increased phosphorylation of ERN1 protein] CTD PMID:29044621 N-acetyl-L-cysteine multiple interactions ISO RGD:1605125 6480464 Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein], Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]] CTD PMID:24394546 , PMID:27784618 N-acetyl-L-cysteine multiple interactions ISO RGD:1558600 6480464 Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein] more ... CTD PMID:25451595 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein] more ... CTD PMID:21198628 , PMID:30633982 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:1605125 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ERN1 protein CTD PMID:19139269 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:1605125 6480464 TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein] CTD PMID:24140863 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein CTD PMID:24140863 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in increased activity of ERN1 protein, TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein] CTD PMID:12486162 , PMID:24140863 naltrexone multiple interactions ISO RGD:1605125 6480464 Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein] CTD PMID:27323860 nicotine multiple interactions ISO RGD:1558600 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Norbinaltorphimine multiple interactions ISO RGD:1605125 6480464 norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein] CTD PMID:27323860 okadaic acid increases expression ISO RGD:1605125 6480464 Okadaic Acid results in increased expression of ERN1 mRNA CTD PMID:28939011 orlistat multiple interactions ISO RGD:1605125 6480464 orlistat affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] CTD PMID:17283163 oxidopamine multiple interactions EXP 6480464 Oxidopamine results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 paracetamol affects expression ISO RGD:1558600 6480464 Acetaminophen affects the expression of ERN1 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1605125 6480464 Acetaminophen results in increased expression of ERN1 mRNA CTD PMID:21420995 , PMID:29067470 paracetamol increases expression ISO RGD:1558600 6480464 Acetaminophen results in increased expression of ERN1 mRNA CTD PMID:18544908 paraquat multiple interactions ISO RGD:1605125 6480464 Paraquat promotes the reaction [MAP3K5 protein results in increased phosphorylation of ERN1 protein] CTD PMID:20929985 paraquat increases expression ISO RGD:1605125 6480464 Paraquat results in increased expression of ERN1 protein modified form CTD PMID:28986289 paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of ERN1 protein CTD PMID:22245251 paraquat increases phosphorylation ISO RGD:1605125 6480464 Paraquat results in increased phosphorylation of ERN1 protein CTD PMID:20929985 , PMID:28986289 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of ERN1 mRNA CTD PMID:19162173 perfluorooctanoic acid increases expression ISO RGD:1605125 6480464 perfluorooctanoic acid results in increased expression of ERN1 protein CTD PMID:26879310 pirinixic acid decreases expression ISO RGD:1558600 6480464 pirinixic acid results in decreased expression of ERN1 mRNA CTD PMID:16985257 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of ERN1 mRNA CTD PMID:19162173 poly(guanylic acid) multiple interactions EXP 6480464 Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 potassium iodide multiple interactions ISO RGD:1605125 6480464 [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA, Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein] CTD PMID:24231001 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of ERN1 mRNA CTD PMID:19162173 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of ERN1 protein] CTD PMID:25088297 propiconazole increases expression ISO RGD:1558600 6480464 propiconazole results in increased expression of ERN1 mRNA CTD PMID:21278054 pyrazinecarboxamide increases expression ISO RGD:1605125 6480464 Pyrazinamide results in increased expression of ERN1 mRNA CTD PMID:28063906 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Sincalide co-treated with Palmitic Acid] results in increased expression of ERN1 protein] more ... CTD PMID:26873426 quercetin increases phosphorylation ISO RGD:1605125 6480464 Quercetin results in increased phosphorylation of ERN1 protein CTD PMID:24612139 rac-lactic acid decreases expression ISO RGD:1605125 6480464 Lactic Acid results in decreased expression of ERN1 mRNA CTD PMID:30851411 resveratrol increases expression ISO RGD:1605125 6480464 resveratrol results in increased expression of ERN1 protein CTD PMID:24264887 resveratrol multiple interactions ISO RGD:1605125 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of ERN1 protein modified form] CTD PMID:24224909 rotenone multiple interactions EXP 6480464 Rotenone results in increased phosphorylation of and results in increased activity of ERN1 protein CTD PMID:12486162 rotenone increases expression ISO RGD:1605125 6480464 Rotenone results in increased expression of ERN1 protein CTD PMID:30141137 rotenone multiple interactions ISO RGD:1605125 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein], MIR384 mRNA promotes the reaction [Rotenone results in increased phosphorylation of ERN1 protein] CTD PMID:26864693 , PMID:30141137 rotenone increases phosphorylation ISO RGD:1605125 6480464 Rotenone results in increased phosphorylation of ERN1 protein CTD PMID:26864693 SCH 23390 multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 sertraline increases expression ISO RGD:1605125 6480464 Sertraline results in increased expression of ERN1 mRNA CTD PMID:24865413 silicon dioxide multiple interactions EXP 6480464 Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of ERN1 protein CTD PMID:31028789 sincalide multiple interactions EXP 6480464 [Palmitic Acid co-treated with Sincalide] results in increased expression of ERN1 mRNA more ... CTD PMID:26873426 sirolimus multiple interactions ISO RGD:1558600 6480464 [Sirolimus co-treated with HRAS protein] results in decreased expression of ERN1 protein, PPARD protein affects the reaction [[Sirolimus co-treated with HRAS protein] results in decreased expression of ERN1 protein] CTD PMID:24898257 sodium arsenite multiple interactions ISO RGD:1605125 6480464 ERN1 affects the reaction [sodium arsenite results in increased expression of ACE mRNA] more ... CTD PMID:28973481 sodium arsenite increases expression ISO RGD:1558600 6480464 sodium arsenite results in increased expression of ERN1 protein CTD PMID:21911445 sodium arsenite increases expression ISO RGD:1605125 6480464 sodium arsenite results in increased expression of ERN1 mRNA CTD PMID:28973481 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of ERN1 mRNA, Sodium Fluoride results in increased expression of ERN1 protein CTD PMID:23707774 , PMID:30633982 sodium fluoride increases phosphorylation EXP 6480464 Sodium Fluoride results in increased phosphorylation of ERN1 protein CTD PMID:30633982 sodium fluoride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ERN1 mRNA], Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased phosphorylation of ERN1 protein] CTD PMID:30633982 sodium fluoride increases expression ISO RGD:1605125 6480464 Sodium Fluoride results in increased expression of ERN1 mRNA, Sodium Fluoride results in increased expression of ERN1 protein CTD PMID:24231001 sodium fluoride multiple interactions ISO RGD:1605125 6480464 [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA, Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein] CTD PMID:24231001 sodium fluoride increases expression ISO RGD:1558600 6480464 Sodium Fluoride results in increased expression of ERN1 mRNA CTD PMID:21626649 streptozocin multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] CTD PMID:20399799 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of ERN1 protein modified form CTD PMID:20399799 succimer multiple interactions ISO RGD:1558600 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ERN1 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ERN1 mRNA CTD PMID:21641980 , PMID:26378955 T-2 Toxin increases expression ISO RGD:1558600 6480464 T-2 Toxin results in increased expression of ERN1 protein CTD PMID:31170431 T-2 Toxin multiple interactions ISO RGD:1605125 6480464 ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein], ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein] CTD PMID:31170431 T-2 Toxin increases expression ISO RGD:1605125 6480464 T-2 Toxin results in increased expression of ERN1 protein CTD PMID:31170431 tacrolimus hydrate increases phosphorylation ISO RGD:1558600 6480464 Tacrolimus results in increased phosphorylation of ERN1 protein CTD PMID:23958496 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of ERN1 protein] CTD PMID:30660605 tauroursodeoxycholic acid multiple interactions ISO RGD:1558600 6480464 tauroursodeoxycholic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 tert-butyl hydroperoxide multiple interactions ISO RGD:1605125 6480464 Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]] more ... CTD PMID:24394546 tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of ERN1 protein CTD PMID:25858767 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of ERN1 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ERN1 mRNA] CTD PMID:31150632 tetrachloromethane increases phosphorylation ISO RGD:1558600 6480464 Carbon Tetrachloride results in increased phosphorylation of ERN1 protein CTD PMID:25827057 , PMID:30538632 tetrachloromethane multiple interactions ISO RGD:1558600 6480464 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of ERN1 protein] CTD PMID:25827057 thapsigargin increases expression ISO RGD:1605125 6480464 Thapsigargin results in increased expression of ERN1 mRNA more ... CTD PMID:17963750 more ... thapsigargin affects splicing ISO RGD:1605125 6480464 Thapsigargin affects the splicing of ERN1 mRNA CTD PMID:27587023 thapsigargin increases phosphorylation ISO RGD:1605125 6480464 Thapsigargin results in increased phosphorylation of ERN1 protein CTD PMID:23576437 , PMID:26264395 thapsigargin increases phosphorylation EXP 6480464 Thapsigargin results in increased phosphorylation of ERN1 protein CTD PMID:24638036 thapsigargin increases phosphorylation ISO RGD:1558600 6480464 Thapsigargin results in increased phosphorylation of ERN1 protein CTD PMID:20493918 , PMID:23576437 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of ERN1 protein CTD PMID:23885834 thapsigargin multiple interactions ISO RGD:1605125 6480464 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] more ... CTD PMID:23576437 more ... thapsigargin multiple interactions ISO RGD:1558600 6480464 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] more ... CTD PMID:20493918 more ... titanium dioxide affects expression ISO RGD:1605125 6480464 titanium dioxide affects the expression of ERN1 protein CTD PMID:30273564 titanium dioxide increases expression ISO RGD:1605125 6480464 titanium dioxide results in increased expression of ERN1 mRNA CTD PMID:30273564 Tributyltin oxide increases expression ISO RGD:1605125 6480464 bis(tri-n-butyltin)oxide results in increased expression of ERN1 mRNA CTD PMID:21601586 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1605125 6480464 tris(2-butoxyethyl) phosphate affects the expression of ERN1 mRNA CTD PMID:29024780 troglitazone decreases expression ISO RGD:1558600 6480464 troglitazone results in decreased expression of ERN1 mRNA CTD PMID:28973697 tunicamycin multiple interactions ISO RGD:1558600 6480464 [Tunicamycin co-treated with HRAS protein] results in increased expression of ERN1 protein more ... CTD PMID:20015086 more ... tunicamycin increases phosphorylation EXP 6480464 Tunicamycin results in increased phosphorylation of ERN1 protein CTD PMID:24892553 tunicamycin multiple interactions EXP 6480464 Guanabenz inhibits the reaction [Tunicamycin results in increased phosphorylation of ERN1 protein] CTD PMID:24892553 tunicamycin multiple interactions ISO RGD:1605125 6480464 ERGIC3 protein inhibits the reaction [Tunicamycin results in increased expression of ERN1 protein] CTD PMID:27588471 tunicamycin increases expression ISO RGD:1558600 6480464 Tunicamycin results in increased expression of ERN1 mRNA CTD PMID:17127020 more ... tunicamycin increases expression ISO RGD:1605125 6480464 Tunicamycin results in increased expression of ERN1 mRNA more ... CTD PMID:19139269 more ... tunicamycin increases phosphorylation ISO RGD:1558600 6480464 Tunicamycin results in increased phosphorylation of ERN1 protein CTD PMID:22001960 , PMID:30253173 urethane increases expression ISO RGD:1605125 6480464 Urethane results in increased expression of ERN1 mRNA CTD PMID:28818685 ursolic acid increases activity ISO RGD:1605125 6480464 ursolic acid results in increased activity of ERN1 protein CTD PMID:24802810 valproic acid increases methylation ISO RGD:1605125 6480464 Valproic Acid results in increased methylation of ERN1 gene CTD PMID:29154799 vemurafenib multiple interactions ISO RGD:1605125 6480464 [KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased expression of ERN1 protein CTD PMID:27222248 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of ERN1 mRNA CTD PMID:23034163
Gene-Chemical Interaction Annotations
