Gene: Plekhm1 (pleckstrin homology and RUN domain containing M1) Rattus norvegicus
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Symbol: Plekhm1
Name: pleckstrin homology and RUN domain containing M1
Description: ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN lysosome localization (ortholog); positive regulation of bone resorption (ortholog); positive regulation of ruffle assembly (ortholog); ASSOCIATED WITH autosomal dominant osteopetrosis 3 (ortholog); autosomal recessive osteopetrosis 6 (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); nucleolus (ortholog); INTERACTS WITH bisphenol A; flutamide; vinclozolin
AGR Description: Predicted to have metal ion binding activity; predicted to be involved in lysosome localization, positive regulation of bone resorption, and positive regulation of ruffle assembly; predicted to localize to the nucleolus; orthologous to human PLEKHM1 (pleckstrin homology and RUN domain containing M1).
Merged Description: Predicted to have metal ion binding activity; predicted to be involved in lysosome localization, positive regulation of bone resorption, and positive regulation of ruffle assembly; predicted to localize to the nucleolus; orthologous to human PLEKHM1 (pleckstrin homology and RUN domain containing M1); INTERACTS WITH bisphenol A; flutamide; vinclozolin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC303584; MGC94075; PH domain-containing family M member 1; pleckstrin homology domain containing, family M (with RUN domain) member 1; pleckstrin homology domain-containing family M member 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01091,451,890 - 91,500,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01091,218,325 - 91,267,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41092,555,565 - 92,603,324 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11092,569,935 - 92,617,694 (-)NCBI
Celera1087,015,274 - 87,063,066 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Plekhm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308010
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.