Pecam1 (platelet and endothelial cell adhesion molecule 1) - Rat Genome Database

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Gene: Pecam1 (platelet and endothelial cell adhesion molecule 1) Rattus norvegicus
Analyze
Symbol: Pecam1
Name: platelet and endothelial cell adhesion molecule 1
RGD ID: 61927
Description: Enables protein phosphatase binding activity. Involved in several processes, including cellular response to interferon-gamma; negative regulation of GTPase activity; and negative regulation of actin filament polymerization. Located in cell surface and ruffle. Used to study pulmonary hypertension. Biomarker of bacterial pneumonia; orchitis; and osteoarthritis. Human ortholog(s) of this gene implicated in coronary artery disease; coronary stenosis; myocardial infarction; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1); PARTICIPATES IN malaria pathway; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 2-acetamidofluorene; 5-azacytidine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CD31; MGC124998; Pecam; PECAM-1; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21091,590,521 - 91,652,279 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
Rnor_6.01094,850,971 - 94,913,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,598,951 - 94,660,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41096,056,220 - 96,057,232 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1090,260,186 - 90,318,290 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
Acute Lung Injury  (IDA)
atherosclerosis  (ISO)
autistic disorder  (ISO)
autoimmune disease  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
babesiosis  (ISO)
bacterial pneumonia  (IEP)
Bone Fractures  (ISO)
Brain Injuries  (IDA)
Breast Neoplasms  (ISO)
chronic myeloid leukemia  (ISO)
chronic venous insufficiency  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
common variable immunodeficiency  (ISO)
corneal neovascularization  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
coronary stenosis  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
Endotoxemia  (ISO)
eosinophilic esophagitis  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IEP)
glioblastoma  (ISO)
Graft vs Host Disease  (ISO)
hyperkalemic periodic paralysis  (ISO)
Limb Ischemia  (ISO)
liver cirrhosis  (ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (IDA,IEP)
myeloid leukemia  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (IMP)
Neovascularization, Pathologic  (ISO)
neurilemmoma  (ISO)
neuroblastoma  (ISO)
Ocular Neovascularization  (ISO)
Optic Nerve Injuries  (IEP)
orchitis  (IEP)
osteoarthritis  (IEP)
ovarian cancer  (ISO)
periodontitis  (ISO)
Peritoneal Fibrosis  (ISO)
peritonitis  (ISO)
polycystic ovary syndrome  (ISO)
polymyalgia rheumatica  (ISO)
Preeclamptic Toxemia  (ISO)
psoriatic arthritis  (ISO)
pterygium  (ISO)
pulmonary hypertension  (IDA)
Radiation Injuries, Experimental  (IEP)
Reperfusion Injury  (IEP,IMP,ISO)
sarcoma  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
sickle cell anemia  (ISO)
spinal muscular atrophy  (ISO)
systemic scleroderma  (ISO)
tauopathy  (ISO)
thrombocytopenia  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
Vascular System Injuries  (IDA)
Venous Thrombosis  (ISO)
Wounds, Penetrating  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetamidofluorene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetic acid  (ISO)
acetylsalicylic acid  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
andrographolide  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
cadmium atom  (ISO)
cannabidiol  (ISO)
carbon monoxide  (EXP)
carrageenan  (EXP)
chalcones  (EXP)
chlorogenic acid  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
cobalt dichloride  (EXP,ISO)
curcumin  (EXP,ISO)
Curcumol  (ISO)
D-glucose  (ISO)
demethoxycurcumin  (EXP)
Destruxin B  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
emodin  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
furosemide  (EXP)
gefitinib  (ISO)
gemcitabine  (ISO)
glucose  (ISO)
hydroquinone  (ISO)
indometacin  (EXP)
isorhamnetin  (ISO)
L-methionine  (ISO)
Lasiocarpine  (ISO)
letrozole  (ISO)
lipopolysaccharide  (ISO)
losartan  (ISO)
metformin  (ISO)
methylglyoxal  (ISO)
monocrotaline  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-nitrosodiethylamine  (EXP)
nicotinic acid  (ISO)
NSC 23766  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
probucol  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rosuvastatin calcium  (ISO)
roxarsone  (ISO)
sarpogrelate  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sorafenib  (EXP)
sphingosine 1-phosphate  (ISO)
streptozocin  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thalidomide  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (EXP)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vitamin E  (ISO)
vorinostat  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
PMID:7589563   PMID:9290466   PMID:10878616   PMID:11078691   PMID:11254359   PMID:12110892   PMID:12477932   PMID:12736726   PMID:12890700   PMID:15489334   PMID:15572031   PMID:15985432  
PMID:16251442   PMID:16455951   PMID:16691571   PMID:17464107   PMID:17563397   PMID:17580308   PMID:17935476   PMID:18332105   PMID:18948084   PMID:19299737   PMID:19342684   PMID:20458337  
PMID:20473743   PMID:20620994   PMID:20724702   PMID:21464233   PMID:21564091   PMID:21708977   PMID:22266279   PMID:23395097   PMID:24009720   PMID:24588994   PMID:26607202   PMID:26702061  
PMID:26706435   PMID:27958302   PMID:31628816   PMID:32437020  


Genomics

Comparative Map Data
Pecam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21091,590,521 - 91,652,279 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
Rnor_6.01094,850,971 - 94,913,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,598,951 - 94,660,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41096,056,220 - 96,057,232 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1090,260,186 - 90,318,290 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
PECAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381764,319,415 - 64,390,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1764,319,415 - 64,413,776 (-)EnsemblGRCh38hg38GRCh38
GRCh371762,396,775 - 62,404,854 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,753,595 - 59,817,743 (-)NCBINCBI36hg18NCBI36
Build 341759,754,144 - 59,817,723NCBI
Celera1756,788,107 - 56,856,790 (-)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1757,766,219 - 57,837,658 (-)NCBIHuRef
CHM1_11762,461,123 - 62,469,204 (-)NCBICHM1_1
Pecam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911106,545,039 - 106,606,107 (-)NCBIGRCm39mm39
GRCm39 Ensembl11106,545,043 - 106,641,454 (-)Ensembl
GRCm3811106,654,213 - 106,715,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,654,217 - 106,750,628 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711106,515,532 - 106,576,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,470,308 - 106,531,371 (-)NCBImm8
Celera11118,385,876 - 118,446,185 (-)NCBICelera
Cytogenetic Map11E1NCBI
Pecam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554787,478,492 - 7,531,188 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554787,448,584 - 7,531,860 (+)NCBIChiLan1.0ChiLan1.0
PECAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11763,511,784 - 63,601,241 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1763,511,784 - 63,579,067 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01758,417,134 - 58,526,409 (-)NCBIMhudiblu_PPA_v0panPan3
PECAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1912,166,124 - 12,219,553 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl912,166,775 - 12,219,778 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha913,062,602 - 13,116,028 (-)NCBI
ROS_Cfam_1.0913,828,912 - 13,882,564 (-)NCBI
ROS_Cfam_1.0 Ensembl913,828,916 - 13,885,280 (-)Ensembl
UMICH_Zoey_3.1912,775,258 - 12,828,596 (-)NCBI
UNSW_CanFamBas_1.0914,703,955 - 14,757,407 (+)NCBI
UU_Cfam_GSD_1.0914,705,590 - 14,758,833 (+)NCBI
Pecam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560214,247,718 - 14,321,139 (+)NCBI
SpeTri2.0NW_0049365414,873,459 - 4,919,787 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PECAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1214,582,481 - 14,723,336 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11214,667,643 - 14,723,296 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21214,661,621 - 14,717,153 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PECAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11656,863,763 - 56,947,479 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1656,880,934 - 56,950,999 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607727,456,525 - 27,565,234 (+)NCBIVero_WHO_p1.0
Pecam1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462487033,293 - 122,536 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127691  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21091,590,681 - 91,590,865 (+)MAPPERmRatBN7.2
Rnor_6.01094,851,132 - 94,851,315NCBIRnor6.0
Rnor_5.01094,599,112 - 94,599,295UniSTSRnor5.0
RGSC_v3.41096,056,381 - 96,056,564UniSTSRGSC3.4
Celera1090,260,347 - 90,260,530UniSTS
RH 3.4 Map10987.4UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091228102104060283Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107437208494965338Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108400727295933025Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)107877551698279596Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
1558652Bw57Body weight QTL 574.20.0008body mass (VT:0001259)body weight (CMO:0000012)1090910316107211142Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)108402232193995963Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107255241693995749Rat
2313856Bp342Blood pressure QTL 3424.40.0001life span trait (VT:0005372)age at time of death (CMO:0001193)108730761796121100Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108256485692369470Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1080515287101325465Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107624608594965338Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108400727295933025Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:585
Count of miRNA genes:259
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000046815
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000094323   ⟹   ENSRNOP00000083671
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105483   ⟹   ENSRNOP00000086124
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106375   ⟹   ENSRNOP00000091045
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110556   ⟹   ENSRNOP00000093793
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110646   ⟹   ENSRNOP00000088286
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,590,522 - 91,652,116 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117408   ⟹   ENSRNOP00000082668
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,613,895 - 91,635,758 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117538   ⟹   ENSRNOP00000088919
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1091,590,521 - 91,652,116 (-)Ensembl
RefSeq Acc Id: NM_031591   ⟹   NP_113779
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,116 (-)NCBI
Rnor_6.01094,850,971 - 94,913,202 (-)NCBI
Rnor_5.01094,598,951 - 94,660,385 (-)NCBI
RGSC_v3.41096,056,220 - 96,057,232 (-)RGD
Celera1090,260,186 - 90,318,290 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085774   ⟹   XP_038941702
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085775   ⟹   XP_038941703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085776   ⟹   XP_038941704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085777   ⟹   XP_038941705
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085778   ⟹   XP_038941706
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,220 (-)NCBI
RefSeq Acc Id: XM_039085779   ⟹   XP_038941707
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085780   ⟹   XP_038941708
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085781   ⟹   XP_038941709
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XR_005489774
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XR_005489776
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_113779   ⟸   NM_031591
- Peptide Label: precursor
- UniProtKB: Q3SWT0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_038941709   ⟸   XM_039085781
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038941707   ⟸   XM_039085779
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038941704   ⟸   XM_039085776
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941708   ⟸   XM_039085780
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038941705   ⟸   XM_039085777
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038941703   ⟸   XM_039085775
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941702   ⟸   XM_039085774
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941706   ⟸   XM_039085778
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000082668   ⟸   ENSRNOT00000117408
RefSeq Acc Id: ENSRNOP00000086124   ⟸   ENSRNOT00000105483
RefSeq Acc Id: ENSRNOP00000083671   ⟸   ENSRNOT00000094323
RefSeq Acc Id: ENSRNOP00000088919   ⟸   ENSRNOT00000117538
RefSeq Acc Id: ENSRNOP00000093793   ⟸   ENSRNOT00000110556
RefSeq Acc Id: ENSRNOP00000088286   ⟸   ENSRNOT00000110646
RefSeq Acc Id: ENSRNOP00000091045   ⟸   ENSRNOT00000106375
Protein Domains
Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3SWT0-F1-model_v2 AlphaFold Q3SWT0 1-678 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61927 AgrOrtholog
BioCyc Gene G2FUF-22930 BioCyc
Ensembl Genes ENSRNOG00000066008 Ensembl, ENTREZGENE
Ensembl Protein ENSRNOP00000082668 ENTREZGENE
  ENSRNOP00000086124 ENTREZGENE
  ENSRNOP00000088286 ENTREZGENE
  ENSRNOP00000088919 ENTREZGENE
  ENSRNOP00000091045 ENTREZGENE
  ENSRNOP00000093793 ENTREZGENE
Ensembl Transcript ENSRNOT00000105483 ENTREZGENE
  ENSRNOT00000106375 ENTREZGENE
  ENSRNOT00000110556 ENTREZGENE
  ENSRNOT00000110646 ENTREZGENE
  ENSRNOT00000117408 ENTREZGENE
  ENSRNOT00000117538 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7368518 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
KEGG Report rno:29583 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124998 IMAGE-MGC_LOAD
NCBI Gene 29583 ENTREZGENE
Pfam Ig_2 UniProtKB/Swiss-Prot
  PF00047 UniProtKB/Swiss-Prot
PhenoGen Pecam1 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
TIGR TC236488
UniProt PECA1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P97635 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-14 Pecam1  platelet and endothelial cell adhesion molecule 1  Pecam1  platelet/endothelial cell adhesion molecule 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Pecam1  platelet/endothelial cell adhesion molecule 1  Pecam  platelet/endothelial cell adhesion molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pecam  platelet/endothelial cell adhesion molecule      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed constitutively on pulmonary arterial, capillary, and venular endothelium 724645
gene_process mediates neutrophil emigration induced by IgG immune complexes during bacterial pneumonia 724645
gene_product member of immunoglobulin (Ig) gene superfamily 724645