Pecam1 (platelet and endothelial cell adhesion molecule 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pecam1 (platelet and endothelial cell adhesion molecule 1) Rattus norvegicus
Analyze
Symbol: Pecam1
Name: platelet and endothelial cell adhesion molecule 1
RGD ID: 61927
Description: Exhibits protein phosphatase binding activity. Involved in several processes, including cellular response to interferon-gamma; negative regulation of GTPase activity; and negative regulation of actin filament polymerization. Localizes to cell surface and ruffle. Used to study pulmonary hypertension. Biomarker of bacterial pneumonia; orchitis; and osteoarthritis. Human ortholog(s) of this gene implicated in coronary artery disease; coronary stenosis; myocardial infarction; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1); PARTICIPATES IN malaria pathway; INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 2-acetamidofluorene; 5-azacytidine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD31; MGC124998; Pecam; PECAM-1; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
Rnor_6.01094,850,971 - 94,913,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,598,951 - 94,660,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41096,056,220 - 96,057,232 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1090,260,186 - 90,318,290 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
Acute Lung Injury  (IDA)
atherosclerosis  (ISO)
autistic disorder  (ISO)
autoimmune disease  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
babesiosis  (ISO)
bacterial pneumonia  (IEP)
Bone Fractures  (ISO)
Brain Injuries  (IDA)
Breast Neoplasms  (ISO)
chronic myeloid leukemia  (ISO)
chronic venous insufficiency  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
common variable immunodeficiency  (ISO)
corneal neovascularization  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
coronary stenosis  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
Endotoxemia  (ISO)
eosinophilic esophagitis  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IEP)
glioblastoma  (ISO)
Graft vs Host Disease  (ISO)
hyperkalemic periodic paralysis  (ISO)
Limb Ischemia  (ISO)
liver cirrhosis  (ISO)
Lung Injury  (ISO)
Lung Reperfusion Injury  (IDA,IEP)
myeloid leukemia  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (IMP)
Neovascularization, Pathologic  (ISO)
neurilemmoma  (ISO)
neuroblastoma  (ISO)
Ocular Neovascularization  (ISO)
Optic Nerve Injuries  (IEP)
orchitis  (IEP)
osteoarthritis  (IEP)
ovarian cancer  (ISO)
periodontitis  (ISO)
Peritoneal Fibrosis  (ISO)
peritonitis  (ISO)
polycystic ovary syndrome  (ISO)
polymyalgia rheumatica  (ISO)
Preeclamptic Toxemia  (ISO)
psoriatic arthritis  (ISO)
pterygium  (ISO)
pulmonary hypertension  (IDA)
Radiation Injuries, Experimental  (IEP)
Reperfusion Injury  (IEP,IMP,ISO)
sarcoma  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
sickle cell anemia  (ISO)
spinal muscular atrophy  (ISO)
systemic scleroderma  (ISO)
tauopathy  (ISO)
thrombocytopenia  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
Vascular System Injuries  (IDA)
Venous Thrombosis  (ISO)
Wounds, Penetrating  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-acetamidofluorene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetic acid  (ISO)
acetylsalicylic acid  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
andrographolide  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
carbon monoxide  (EXP)
carrageenan  (EXP)
chalcones  (EXP)
chlorogenic acid  (EXP)
choline  (ISO)
chrysene  (ISO)
cobalt dichloride  (EXP,ISO)
curcumin  (EXP,ISO)
D-glucose  (ISO)
demethoxycurcumin  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
emodin  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
furosemide  (EXP)
gefitinib  (ISO)
gemcitabine  (ISO)
glucose  (ISO)
hydroquinone  (ISO)
indometacin  (EXP)
isorhamnetin  (ISO)
L-methionine  (ISO)
Lasiocarpine  (ISO)
letrozole  (ISO)
lipopolysaccharide  (ISO)
losartan  (ISO)
methylglyoxal  (ISO)
monocrotaline  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-nitrosodiethylamine  (EXP)
nicotinic acid  (ISO)
NSC 23766  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
probucol  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rosuvastatin calcium  (ISO)
roxarsone  (ISO)
sarpogrelate  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sphingosine 1-phosphate  (ISO)
streptozocin  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thalidomide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (EXP)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vitamin E  (ISO)
vorinostat  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Asano Y, etal., Am J Pathol. 2010 Apr;176(4):1983-98. doi: 10.2353/ajpath.2010.090593. Epub 2010 Mar 12.
2. Baelde HJ, etal., Am J Kidney Dis. 2004 Apr;43(4):636-50.
3. Blankenberg FG, etal., J Nucl Med. 2011 Oct;52(10):1630-7. Epub 2011 Sep 2.
4. Bogen S, etal., J Exp Med. 1994 Mar 1;179(3):1059-64.
5. Breen DM, etal., Atherosclerosis. 2012 Jun;222(2):375-81. Epub 2012 Mar 27.
6. Breithaupt-Faloppa AC, etal., J Surg Res. 2012 Jul;176(1):195-201. Epub 2011 Jul 28.
7. Brudecki L, etal., Infect Immun. 2012 Jun;80(6):2026-34. Epub 2012 Mar 26.
8. Cameron S, etal., Exp Mol Pathol. 2012 Apr;92(2):243-58. Epub 2011 Dec 29.
9. Chian CF, etal., Shock. 2012 May 15.
10. Couty JP, etal., J Neurochem. 2007 Oct;103(2):793-801. Epub 2007 Jul 27.
11. de Vries M, etal., Virchows Arch. 2012 Jun;460(6):629-36. Epub 2012 May 4.
12. Dhanjal TS, etal., Blood. 2007 May 15;109(10):4237-44. Epub 2007 Jan 18.
13. Elrayess MA, etal., Atherosclerosis. 2003 May;168(1):131-8.
14. Elrayess MA, etal., Atherosclerosis. 2004 Nov;177(1):127-35.
15. Fang F, etal., Zhonghua Xin Xue Guan Bing Za Zhi. 2011 Dec;39(12):1110-6.
16. Fiocco U, etal., J Rheumatol Suppl. 2012 Jul;89:61-4.
17. Gao HK, etal., Hepatobiliary Pancreat Dis Int. 2003 Aug;2(3):463-6.
18. Gao HK, etal., World J Gastroenterol. 2005 Feb 7;11(5):661-4.
19. Gardemann A, etal., Thromb Haemost. 2000 Apr;83(4):629.
20. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
21. Gaudreault N, etal., Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):264-72. Epub 2011 Nov 3.
22. GOA data from the GO Consortium
23. Gompels LL, etal., Arthritis Res Ther. 2011;13(5):R161. Epub 2011 Oct 7.
24. Groyer E, etal., J Am Coll Cardiol. 2007 Jul 24;50(4):344-50. Epub 2007 Jul 6.
25. Guazzone VA, etal., Reproduction. 2012 May;143(5):651-62. Epub 2012 Feb 20.
26. Gumina RJ, etal., Circulation. 1996 Dec 15;94(12):3327-33.
27. Hebeda CB, etal., J Ethnopharmacol. 2011 May 17;135(2):261-9. doi: 10.1016/j.jep.2011.02.033. Epub 2011 Mar 15.
28. Huang H, etal., Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5825-32. doi: 10.1167/iovs.10-5576. Epub 2010 Jun 10.
29. Ibrahim S, etal., Cancer. 2003 Apr 15;97(8):1914-9.
30. Ikarashi N, etal., Clin Exp Hypertens. 2012;34(8):575-81. doi: 10.3109/10641963.2012.681728. Epub 2012 May 4.
31. Jaworski T, etal., Am J Pathol. 2011 Oct;179(4):2001-15. Epub 2011 Aug 10.
32. Jhanji V, etal., Br J Ophthalmol. 2011 Sep;95(9):1309-15. Epub 2011 Jun 30.
33. Jiang JF, etal., Lancet Infect Dis. 2015 Feb;15(2):196-203. doi: 10.1016/S1473-3099(14)71046-1. Epub 2014 Dec 22.
34. Jimenez-Andrade JM and Mantyh PW, Arthritis Res Ther. 2012 May 1;14(3):R101.
35. Katzenell S, etal., Thromb Res. 2012 Apr 23.
36. Kiersnowska-Rogowska B, etal., Przegl Lek. 2005;62(8):772-4.
37. Kitamura M, etal., Chem Biol Interact. 2012 Jan 5;195(1):95-104. doi: 10.1016/j.cbi.2011.11.002. Epub 2011 Nov 15.
38. Kong SL, etal., Virus Res. 2009 Nov;145(2):260-9. Epub 2009 Jul 25.
39. Kroll H, etal., Blood. 2000 Aug 15;96(4):1409-14.
40. Li G, etal., Mol Med Rep. 2015 Aug;12(2):2203-10. doi: 10.3892/mmr.2015.3586. Epub 2015 Apr 1.
41. Li TS, etal., PLoS One. 2011;6(10):e25543. Epub 2011 Oct 3.
42. Listi F, etal., Eur J Immunogenet. 2004 Aug;31(4):175-8.
43. Liu G, etal., Blood. 2012 Jul 17.
44. Liu T, etal., J Sex Med. 2011 Oct;8(10):2761-72. doi: 10.1111/j.1743-6109.2011.02421.x.
45. Liu YM, etal., Zhonghua Yan Ke Za Zhi. 2011 Dec;47(12):1089-95.
46. Livezeanu C, etal., Rom J Morphol Embryol. 2011;52(3):837-44.
47. MGD data from the GO Consortium
48. Miyazaki R, etal., Clin Sci (Lond). 2012 Aug 1;123(4):241-9.
49. Mkonyi LE, etal., J Dent Res. 2012 Jan;91(1):71-7. Epub 2011 Oct 6.
50. Mourad H, etal., Egypt J Immunol. 2008;15(1):25-37.
51. Nassar D, etal., PLoS One. 2012;7(5):e37084. Epub 2012 May 16.
52. NCBI rat LocusLink and RefSeq merged data July 26, 2002
53. Neubauer K, etal., BMC Physiol. 2008 May 8;8:9.
54. Onore CE, etal., Biol Psychiatry. 2012 Jun 19.
55. Oraei M, etal., J Investig Allergol Clin Immunol. 2012;22(3):160-7.
56. Pepene CE Gynecol Endocrinol. 2012 May;28(5):370-4. Epub 2012 Mar 29.
57. Persad R, etal., J Pediatr Gastroenterol Nutr. 2012 Feb 10.
58. Pickarski M, etal., BMC Musculoskelet Disord. 2011 Aug 24;12:197.
59. Pinter E, etal., Am J Pathol. 1999 May;154(5):1367-79.
60. Pipeline to import KEGG annotations from KEGG into RGD
61. Pirro M, etal., J Intern Med. 2011 Dec 30. doi: 10.1111/j.1365-2796.2011.02510.x.
62. Pradhan AK and Chakraborty S, Leuk Lymphoma. 2014 Apr;55(4):954-6. doi: 10.3109/10428194.2013.815350. Epub 2013 Jul 24.
63. Prasad S, etal., Clin Cancer Res. 2012 Jul 25.
64. Privratsky JR, etal., Life Sci. 2012 Jan 30;90(5-6):177-84. Epub 2011 Nov 18.
65. Pullen NA, etal., J Neurooncol. 2012 Feb;106(3):461-71. Epub 2011 Aug 21.
66. Qu Y, etal., Cancer Gene Ther. 2011 Sep;18(9):663-73. doi: 10.1038/cgt.2011.37. Epub 2011 Jul 15.
67. Rautou PE, etal., Gastroenterology. 2012 Jul;143(1):166-176.e6. Epub 2012 Mar 30.
68. RGD automated data pipeline
69. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
70. RGD automated import pipeline for gene-chemical interactions
71. Rokutanda T, etal., Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2872-80. Epub 2011 Sep 22.
72. Sagawa K, etal., J Biol Chem. 1997 Dec 5;272(49):31086-91.
73. Sagawa K, etal., J Biol Chem. 1997 May 16;272(20):13412-8.
74. Sasaoka T, etal., Ann N Y Acad Sci. 2001 Dec;947:259-69; discussion 269-70.
75. Sebastian A, etal., Wound Repair Regen. 2011 Nov;19(6):693-708. doi: 10.1111/j.1524-475X.2011.00736.x. Epub 2011 Oct 19.
76. Shalhoub J, etal., Stroke. 2011 Dec;42(12):3634-6. Epub 2011 Sep 29.
77. Shimoyama T, etal., Med Sci Monit. 2006 Feb;12(2):BR51-6. Epub 2006 Jan 26.
78. Singhal J, etal., Cancer Prev Res (Phila). 2012 Mar;5(3):473-83. Epub 2011 Dec 15.
79. Somers E, etal., Neuromuscul Disord. 2012 May;22(5):435-42. Epub 2011 Dec 7.
80. Sun CK, etal., J Transl Med. 2011 Jul 22;9:118.
81. Sun Z, etal., J Surg Res. 2002 Jun 15;105(2):220-33.
82. Tada Y, etal., Arthritis Rheum. 2003 Nov;48(11):3280-90.
83. Tasaka S, etal., Am J Respir Crit Care Med 2003 Jan 15;167(2):164-70.
84. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
85. Thompson RD, etal., J Immunol. 2000 Jul 1;165(1):426-34.
86. Tisato V, etal., PLoS One. 2012;7(6):e39543. Epub 2012 Jun 21.
87. Vaporciyan AA, etal., Science. 1993 Dec 3;262(5139):1580-2.
88. Wang B, etal., J Neurol Sci. 2012 Aug 15;319(1-2):117-23. Epub 2012 Jun 2.
89. Wang XX, etal., Plast Reconstr Surg. 2011 Aug;128(2):395-405.
90. Wenzel K, etal., Hum Mutat. 1999 Dec;14(6):545.
91. Yadav VR, etal., Int J Cancer. 2012 May 1;130(9):2176-84. doi: 10.1002/ijc.26251. Epub 2011 Sep 12.
92. Yang LL, etal., Int J Ophthalmol. 2012;5(1):32-7. Epub 2012 Feb 18.
93. Ye Y, etal., Biol Pharm Bull. 2012;35(3):355-61.
94. Yuan L and Liu X, Mol Med Rep. 2015 Apr;11(4):2449-58. doi: 10.3892/mmr.2014.3082. Epub 2014 Dec 11.
Additional References at PubMed
PMID:7589563   PMID:9290466   PMID:10878616   PMID:11078691   PMID:11254359   PMID:12110892   PMID:12477932   PMID:12736726   PMID:12890700   PMID:15489334   PMID:15572031   PMID:15985432  
PMID:16251442   PMID:16455951   PMID:16691571   PMID:17464107   PMID:17563397   PMID:17580308   PMID:17935476   PMID:18332105   PMID:18948084   PMID:19299737   PMID:19342684   PMID:20458337  
PMID:20473743   PMID:20620994   PMID:20724702   PMID:21464233   PMID:21564091   PMID:21708977   PMID:22266279   PMID:23395097   PMID:24009720   PMID:24588994   PMID:26607202   PMID:26702061  
PMID:26706435   PMID:27958302   PMID:32437020  


Genomics

Comparative Map Data
Pecam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
Rnor_6.01094,850,971 - 94,913,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,598,951 - 94,660,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41096,056,220 - 96,057,232 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1090,260,186 - 90,318,290 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
PECAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1764,319,415 - 64,413,776 (-)EnsemblGRCh38hg38GRCh38
GRCh381764,319,415 - 64,413,844 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371762,396,775 - 62,404,854 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,753,595 - 59,817,743 (-)NCBINCBI36hg18NCBI36
Build 341759,754,144 - 59,817,723NCBI
Celera1756,788,107 - 56,856,790 (-)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1757,766,219 - 57,837,658 (-)NCBIHuRef
CHM1_11762,461,123 - 62,469,204 (-)NCBICHM1_1
Pecam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911106,545,039 - 106,606,107 (-)NCBIGRCm39mm39
GRCm39 Ensembl11106,545,043 - 106,641,454 (-)Ensembl
GRCm3811106,654,213 - 106,715,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,654,217 - 106,750,628 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711106,515,532 - 106,576,595 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,470,308 - 106,531,371 (-)NCBImm8
Celera11118,385,876 - 118,446,185 (-)NCBICelera
Cytogenetic Map11E1NCBI
Pecam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554787,478,492 - 7,531,188 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554787,448,584 - 7,531,860 (+)NCBIChiLan1.0ChiLan1.0
PECAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11763,511,784 - 63,601,241 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1763,511,784 - 63,579,067 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01758,417,134 - 58,526,409 (-)NCBIMhudiblu_PPA_v0panPan3
PECAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1912,166,124 - 12,219,553 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl912,166,775 - 12,219,778 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha913,062,602 - 13,116,028 (-)NCBI
ROS_Cfam_1.0913,828,912 - 13,882,564 (-)NCBI
UMICH_Zoey_3.1912,775,258 - 12,828,596 (-)NCBI
UNSW_CanFamBas_1.0914,703,955 - 14,757,407 (+)NCBI
UU_Cfam_GSD_1.0914,705,590 - 14,758,833 (+)NCBI
Pecam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560214,247,718 - 14,321,139 (+)NCBI
SpeTri2.0NW_0049365414,873,459 - 4,919,787 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PECAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1214,582,481 - 14,723,336 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11214,667,643 - 14,723,296 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21214,661,621 - 14,717,153 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PECAM1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11656,863,763 - 56,947,479 (+)NCBI
ChlSab1.1 Ensembl1656,880,934 - 56,950,999 (+)Ensembl
Pecam1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462487033,293 - 122,536 (-)NCBI

Position Markers
RH127691  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01094,851,132 - 94,851,315NCBIRnor6.0
Rnor_5.01094,599,112 - 94,599,295UniSTSRnor5.0
RGSC_v3.41096,056,381 - 96,056,564UniSTSRGSC3.4
Celera1090,260,347 - 90,260,530UniSTS
RH 3.4 Map10987.4UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)1020170031102897474Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)1027237530101482600Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1027237530102427718Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103618592995845311Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1041260363106105607Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1043289657108540162Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104659302198939209Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105063833795638337Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105310471898104718Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1053621375112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1053621375112626471Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105362581598939209Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)1055224855100224855Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1055678976112626471Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)1055679084102427604Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1056698730101698730Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1060450007105450007Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1060875260105875260Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1060875260105875260Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1060875260105875260Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1062096293107096293Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)1064648175101691360Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1064648175102149713Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1064648175102149713Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1065590122110590122Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1065992275110992275Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1065992275110992275Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1067880046112626471Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1067988218110992091Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1069123603101482600Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1069385595112626471Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1069385595112626471Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1070166960112626471Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1070800069112626471Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1071692298112626471Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1073008136112626471Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1073008136112626471Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1073008136112626471Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1073467158112626471Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107504539197308358Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1075544754112626471Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1075544754112626471Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107598380599492217Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107598380599492217Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107705574198282519Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107897027998282519Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1078970279112626471Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1079927661112626471Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1080239190112626471Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)1081515116101758478Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1083389828104994768Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1085079943112626471Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108551382295638337Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1086566908112626471Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108696256399303173Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108696256399303173Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)108697786197308569Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1088544136107545372Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1090041957112626471Rat
2313856Bp342Blood pressure QTL 3424.40.0001life span trait (VT:0005372)age at time of death (CMO:0001193)109029689799492409Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1090296897112626471Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)109154814599492409Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1091689348112626471Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1093662786112626471Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1093662786112626471Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1093662786112626471Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1093662786112626471Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)93662786112626471Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)93662786112626471Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1093886117110992275Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1093886117112626471Rat
1558652Bw57Body weight QTL 574.20.0008body mass (VT:0001259)body weight (CMO:0000012)1094170766112626471Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1094486204107857673Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:585
Count of miRNA genes:259
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000046815
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_031591   ⟹   NP_113779
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,116 (-)NCBI
Rnor_6.01094,850,971 - 94,913,202 (-)NCBI
Rnor_5.01094,598,951 - 94,660,385 (-)NCBI
RGSC_v3.41096,056,220 - 96,057,232 (-)RGD
Celera1090,260,186 - 90,318,290 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085774   ⟹   XP_038941702
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085775   ⟹   XP_038941703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085776   ⟹   XP_038941704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085777   ⟹   XP_038941705
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085778   ⟹   XP_038941706
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,220 (-)NCBI
RefSeq Acc Id: XM_039085779   ⟹   XP_038941707
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085780   ⟹   XP_038941708
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XM_039085781   ⟹   XP_038941709
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XR_005489774
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
RefSeq Acc Id: XR_005489776
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21091,590,521 - 91,652,279 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_113779   ⟸   NM_031591
- Peptide Label: precursor
- UniProtKB: Q3SWT0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_038941709   ⟸   XM_039085781
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038941707   ⟸   XM_039085779
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038941704   ⟸   XM_039085776
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941708   ⟸   XM_039085780
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038941705   ⟸   XM_039085777
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038941703   ⟸   XM_039085775
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941702   ⟸   XM_039085774
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941706   ⟸   XM_039085778
- Peptide Label: isoform X5
Protein Domains
Ig-like C2-type


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61927 AgrOrtholog
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7368518 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
KEGG Report rno:29583 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124998 IMAGE-MGC_LOAD
NCBI Gene 29583 ENTREZGENE
Pfam Ig_2 UniProtKB/Swiss-Prot
  PF00047 UniProtKB/Swiss-Prot
PhenoGen Pecam1 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
TIGR TC236488
UniProt PECA1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P97635 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-14 Pecam1  platelet and endothelial cell adhesion molecule 1  Pecam1  platelet/endothelial cell adhesion molecule 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Pecam1  platelet/endothelial cell adhesion molecule 1  Pecam  platelet/endothelial cell adhesion molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pecam  platelet/endothelial cell adhesion molecule      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed constitutively on pulmonary arterial, capillary, and venular endothelium 724645
gene_process mediates neutrophil emigration induced by IgG immune complexes during bacterial pneumonia 724645
gene_product member of immunoglobulin (Ig) gene superfamily 724645