Gene: Grn (granulin precursor) Rattus norvegicus
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Symbol: Grn
Name: granulin precursor
Description: ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN chondrocyte proliferation; male mating behavior; neural precursor cell proliferation; ASSOCIATED WITH status epilepticus; Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); endosome (ortholog); extracellular space (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acrogranin; granulin; granulins; PGRN; proepithelin; progranulin; progranulin ; prostate cancer cell-derived growth factor
Orthologs:
Homo sapiens (human) : GRN (granulin precursor)  HGNC  Alliance
Mus musculus (house mouse) : Grn (granulin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grn (granulin precursor)
Pan paniscus (bonobo/pygmy chimpanzee) : GRN (granulin precursor)
Canis lupus familiaris (dog) : GRN (granulin precursor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grn (granulin precursor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01090,377,103 - 90,383,207 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01090,165,634 - 90,171,738 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,536,135 - 91,542,239 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11091,552,883 - 91,556,599 (+)NCBI
Celera1086,096,583 - 86,102,687 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Grn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61983
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE