Gene: Itga2b (integrin subunit alpha 2b) Rattus norvegicus
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Symbol: Itga2b
Name: integrin subunit alpha 2b
Description: Exhibits fibrinogen binding activity; involved in platelet aggregation and positive regulation of leukocyte migration; localizes to the cell surface; orthologous to human ITGA2B (integrin subunit alpha 2b); PARTICIPATES IN abciximab pharmacodynamics pathway; ephrin - ephrin receptor bidirectional signaling axis; eptifibatide pharmacodynamics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: MODEL
Also known as: integrin alpha 2b (Cd41b); integrin alpha-IIb; integrin, alpha 2B; LOC685269; similar to Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen)
Orthologs:
Homo sapiens (human) : ITGA2B (integrin subunit alpha 2b)  HGNC  Alliance
Mus musculus (house mouse) : Itga2b (integrin alpha 2b)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga2b (integrin subunit alpha 2b)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA2B (integrin subunit alpha 2b)
Canis lupus familiaris (dog) : ITGA2B (integrin subunit alpha 2b)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga2b (integrin subunit alpha 2b)
Sus scrofa (pig) : ITGA2B (integrin subunit alpha 2b)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01090,397,960 - 90,416,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01090,186,491 - 90,205,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,557,086 - 91,574,194 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1086,112,796 - 86,134,968 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itga2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1596428
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.