Gene: Itgb3 (integrin subunit beta 3) Rattus norvegicus
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Symbol: Itgb3
Name: integrin subunit beta 3
Description: ENCODES a protein that exhibits fibrinogen binding; C-X3-C chemokine binding (ortholog); cell adhesion molecule binding (ortholog); INVOLVED IN cellular response to drug; cellular response to insulin-like growth factor stimulus; cellular response to mechanical stimulus; PARTICIPATES IN integrin mediated signaling pathway; abciximab pharmacodynamics pathway; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH Arterial Occlusive Diseases; bacterial pneumonia; Carotid Artery Injuries; FOUND IN apical plasma membrane; cell surface; focal adhesion; INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin, beta 3
Orthologs:
Homo sapiens (human) : ITGB3 (integrin subunit beta 3)  HGNC  Alliance
Mus musculus (house mouse) : Itgb3 (integrin beta 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb3 (integrin subunit beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB3 (integrin subunit beta 3)
Canis lupus familiaris (dog) : ITGB3 (integrin subunit beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb3 (integrin subunit beta 3)
Sus scrofa (pig) : ITGB3 (integrin subunit beta 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01092,667,869 - 92,783,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01092,424,545 - 92,538,859 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1088,202,821 - 88,257,185 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itgb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628868
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE