Gene: Car4 (carbonic anhydrase 4) Rattus norvegicus
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Symbol: Car4
Name: carbonic anhydrase 4
Description: ENCODES a protein that exhibits carbonate dehydratase activity; INVOLVED IN animal organ development; response to drug; response to steroid hormone; ASSOCIATED WITH Colonic Neoplasms (ortholog); retinitis pigmentosa (ortholog); retinitis pigmentosa 17 (ortholog); FOUND IN apical plasma membrane; sarcolemma; sarcoplasmic reticulum; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 3,7-dihydropurine-6-thione
AGR Description: Exhibits carbonate dehydratase activity; involved in animal organ development, response to drug, and response to steroid hormone; localizes to the apical plasma membrane, sarcolemma, and sarcoplasmic reticulum; orthologous to human CA4 (carbonic anhydrase 4).
Merged Description: Exhibits carbonate dehydratase activity; involved in animal organ development, response to drug, and response to steroid hormone; localizes to the apical plasma membrane, sarcolemma, and sarcoplasmic reticulum; orthologous to human CA4 (carbonic anhydrase 4); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CA-IV; Ca4; carbonate dehydratase IV; carbonic anhydrase IV
Orthologs:
Homo sapiens (human) : CA4 (carbonic anhydrase 4)  HGNC  Alliance
Mus musculus (house mouse) : Car4 (carbonic anhydrase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ca4 (carbonic anhydrase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CA4 (carbonic anhydrase 4)
Canis lupus familiaris (dog) : CA4 (carbonic anhydrase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ca4 (carbonic anhydrase 4)
Sus scrofa (pig) : CA4 (carbonic anhydrase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01072,272,286 - 72,281,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01072,173,022 - 72,188,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,229,211 - 73,237,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11073,243,580 - 73,252,077 (+)NCBI
Celera1068,755,736 - 68,764,294 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Car4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2242
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.