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Gene: Gip (gastric inhibitory polypeptide) Rattus norvegicus
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Symbol: Gip
Name: gastric inhibitory polypeptide
Description: Exhibits signaling receptor binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of glucose transmembrane transport; and triglyceride homeostasis. Localizes to the cytoplasm; extracellular space; and neuronal cell body. Used to study obesity and type 2 diabetes mellitus. Biomarker of hyperinsulinism; hypothyroidism; obesity; and pancreas disease. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human GIP (gastric inhibitory polypeptide); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucose-dependent insulinotropic peptide; glucose-dependent insulinotropic polypeptide; Gludins; RATGLUDINS
Orthologs:
Homo sapiens (human) : GIP (gastric inhibitory polypeptide)  HGNC  Alliance
Mus musculus (house mouse) : Gip (gastric inhibitory polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gip (gastric inhibitory polypeptide)
Pan paniscus (bonobo/pygmy chimpanzee) : GIP (gastric inhibitory polypeptide)
Canis lupus familiaris (dog) : GIP (gastric inhibitory polypeptide)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gip (gastric inhibitory polypeptide)
Sus scrofa (pig) : GIP (gastric inhibitory polypeptide)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01083,835,080 - 83,848,399 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01083,645,328 - 83,653,501 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41084,732,705 - 84,740,801 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11084,747,074 - 84,755,168 (+)NCBI
Celera1079,736,495 - 79,744,591 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gip
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2709
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.