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Gene: Nme1 (NME/NM23 nucleoside diphosphate kinase 1) Rattus norvegicus
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Symbol: Nme1
Name: NME/NM23 nucleoside diphosphate kinase 1
Description: Exhibits several functions, including DNA binding activity; gamma-tubulin binding activity; and nucleoside diphosphate kinase activity. Involved in several processes, including cellular response to glucose stimulus; nervous system development; and response to testosterone. Localizes to the centrosome and cytoplasm. Colocalizes with the intermediate filament. Human ortholog(s) of this gene implicated in neuroblastoma; ovary epithelial cancer; and teratoma. Orthologous to human NME1 (NME/NM23 nucleoside diphosphate kinase 1); PARTICIPATES IN adefovir pharmacokinetics pathway; de novo pyrimidine biosynthetic pathway; E-cadherin signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: expressed in non-metastatic cells 1; expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase); expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase); metastasis inhibition factor NM23; NDK A; NDP kinase A; NDP kinase beta; non-metastatic cells 1, protein (NM23A) expressed in; nucleoside diphosphate kinase A; nucloside diphosphate kinase; tumor metastatic process-associated protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01081,657,152 - 81,666,542 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01081,487,114 - 81,496,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41082,591,705 - 82,601,075 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11082,606,074 - 82,615,445 (-)NCBI
Celera1077,703,467 - 77,712,916 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nme1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70497
Created: 2002-05-02
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.