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Gene: Hap1 (huntingtin-associated protein 1) Rattus norvegicus
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Symbol: Hap1
Name: huntingtin-associated protein 1
Description: Exhibits several functions, including brain-derived neurotrophic factor binding activity; identical protein binding activity; and ion channel binding activity. Involved in several processes, including axonal transport; generation of neurons; and positive regulation of cell communication. Localizes to several cellular components, including the distal axon; postsynaptic cytosol; and presynaptic cytosol. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human HAP1 (huntingtin associated protein 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HAP-1; HAP1-A; HAP1-B
Orthologs:
Homo sapiens (human) : HAP1 (huntingtin associated protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Hap1 (huntingtin-associated protein 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HAP1 (huntingtin associated protein 1)
Canis lupus familiaris (dog) : HAP1 (huntingtin associated protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hap1 (huntingtin associated protein 1)
Sus scrofa (pig) : HAP1 (huntingtin associated protein 1)
Chlorocebus sabaeus (African green monkey) : HAP1 (huntingtin associated protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01088,257,975 - 88,266,210 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,257,976 - 88,266,210 (-)Ensembl
Rnor_5.01088,051,219 - 88,059,478 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,285,396 - 89,293,631 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,299,766 - 89,308,001 (-)NCBI
Celera1083,995,991 - 84,004,228 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68327
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.