Gene: Hsd17b1 (hydroxysteroid (17-beta) dehydrogenase 1) Rattus norvegicus
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Symbol: Hsd17b1
Name: hydroxysteroid (17-beta) dehydrogenase 1
Description: ENCODES a protein that exhibits estradiol 17-beta-dehydrogenase activity; testosterone dehydrogenase (NAD+) activity; estradiol binding (ortholog); INVOLVED IN bone development; cellular response to metal ion; estrogen biosynthetic process; PARTICIPATES IN estradiol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH Abortion, Spontaneous (ortholog); endometriosis (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm; cytosol; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17-beta-HSD 1; 17-beta-hydroxysteroid dehydrogenase type 1; 17BHD1; estradiol 17-beta-dehydrogenase 1; hydroxysteroid 17-beta dehydrogenase 1; Hydroxysteroid dehydrogenase 17 beta type 1; Hydroxysteroid dehydrogenase 17 beta, type 1
Orthologs:
Homo sapiens (human) : HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Hsd17b1 (hydroxysteroid (17-beta) dehydrogenase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsd17b1 (hydroxysteroid 17-beta dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1)
Canis lupus familiaris (dog) : HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd17b1 (hydroxysteroid 17-beta dehydrogenase 1)
Sus scrofa (pig) : HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01088,987,558 - 88,989,758 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01088,786,054 - 88,788,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,094,249 - 90,096,451 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,108,618 - 90,110,820 (+)NCBI
Celera1084,727,443 - 84,729,643 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hsd17b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2836
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE