Lig3 (DNA ligase 3) - Rat Genome Database

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Gene: Lig3 (DNA ligase 3) Rattus norvegicus
Analyze
Symbol: Lig3
Name: DNA ligase 3
RGD ID: 1309875
Description: Enables DNA ligase activity. Involved in base-excision repair, DNA ligation. Predicted to be located in mitochondrion; nucleoplasm; and synaptonemal complex. Predicted to be part of DNA ligase III-XRCC1 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 20 and pancreatic cancer. Orthologous to human LIG3 (DNA ligase 3); PARTICIPATES IN nucleotide excision repair pathway; base excision repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-hydroperoxycyclophosphamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA ligase (ATP) 3; ligase III, DNA, ATP-dependent; LOC303369
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp301
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,215,371 - 68,238,705 (+)NCBIGRCr8
mRatBN7.21067,717,808 - 67,741,141 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1067,717,812 - 67,798,414 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1072,337,877 - 72,361,210 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01071,843,252 - 71,866,586 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,305,075 - 67,328,397 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01070,134,734 - 70,158,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,134,729 - 70,158,055 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,765,441 - 69,788,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,000,287 - 71,021,398 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11071,013,909 - 71,035,020 (+)NCBI
Celera1066,662,184 - 66,683,295 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroperoxycyclophosphamide  (EXP)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
clofibrate  (ISO)
coumarin  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
glyphosate  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
ivermectin  (ISO)
methyl methanesulfonate  (ISO)
Methylazoxymethanol acetate  (EXP)
miconazole  (EXP)
monocrotophos  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. DNA polymerases and repair synthesis in NER in human cells. Lehmann AR DNA Repair (Amst). 2011 Jul 15;10(7):730-3. doi: 10.1016/j.dnarep.2011.04.023. Epub 2011 May 20.
4. DNA repair gene polymorphisms and risk of pancreatic cancer. Li D, etal., Clin Cancer Res. 2009 Jan 15;15(2):740-6.
5. Ischemic preconditioning induces XRCC1, DNA polymerase-beta, and DNA ligase III and correlates with enhanced base excision repair. Li N, etal., DNA Repair (Amst). 2007 Sep 1;6(9):1297-306. Epub 2007 Apr 6.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:7565692   PMID:8532526   PMID:9001252   PMID:9809069   PMID:10207110   PMID:12477932   PMID:16648486   PMID:19589734   PMID:21390131   PMID:21390132   PMID:21655080   PMID:21878356  
PMID:24674627   PMID:24837021   PMID:37315345  


Genomics

Comparative Map Data
Lig3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,215,371 - 68,238,705 (+)NCBIGRCr8
mRatBN7.21067,717,808 - 67,741,141 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1067,717,812 - 67,798,414 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1072,337,877 - 72,361,210 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01071,843,252 - 71,866,586 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,305,075 - 67,328,397 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01070,134,734 - 70,158,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,134,729 - 70,158,055 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,765,441 - 69,788,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,000,287 - 71,021,398 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11071,013,909 - 71,035,020 (+)NCBI
Celera1066,662,184 - 66,683,295 (+)NCBICelera
Cytogenetic Map10q26NCBI
LIG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381734,980,512 - 35,010,872 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1734,980,512 - 35,009,743 (+)EnsemblGRCh38hg38GRCh38
GRCh371733,307,531 - 33,336,762 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361730,331,651 - 30,356,201 (+)NCBINCBI36Build 36hg18NCBI36
Build 341730,331,696 - 30,355,936NCBI
Celera1730,217,714 - 30,242,284 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1729,493,447 - 29,518,012 (+)NCBIHuRef
CHM1_11733,371,911 - 33,396,481 (+)NCBICHM1_1
T2T-CHM13v2.01735,928,368 - 35,957,659 (+)NCBIT2T-CHM13v2.0
Lig3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,671,977 - 82,695,100 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1182,671,934 - 82,695,100 (+)EnsemblGRCm39 Ensembl
GRCm381182,781,109 - 82,804,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,781,108 - 82,804,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,594,637 - 82,617,776 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361182,597,330 - 82,620,469 (+)NCBIMGSCv36mm8
Celera1192,400,612 - 92,423,646 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.23NCBI
Lig3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554819,696,054 - 9,715,637 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554819,696,050 - 9,716,154 (+)NCBIChiLan1.0ChiLan1.0
LIG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21929,456,509 - 29,487,762 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11731,342,056 - 31,367,159 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,776,483 - 21,805,706 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11722,073,487 - 22,097,754 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1722,074,046 - 22,095,220 (-)Ensemblpanpan1.1panPan2
LIG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1938,346,275 - 38,366,634 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl938,346,199 - 38,366,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha937,569,261 - 37,590,027 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0939,158,185 - 39,178,954 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl939,155,826 - 39,178,934 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1937,940,790 - 37,961,563 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0938,226,708 - 38,247,470 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0938,314,196 - 38,334,891 (-)NCBIUU_Cfam_GSD_1.0
Lig3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560237,328,228 - 37,350,583 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936538206,839 - 226,441 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936538206,179 - 228,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,153,397 - 40,183,622 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11240,153,105 - 40,205,077 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,714,491 - 41,773,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11628,487,953 - 28,511,945 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1628,490,434 - 28,511,130 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660751,476,469 - 1,500,221 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lig3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248752,872,357 - 2,893,967 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248752,871,944 - 2,907,757 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lig3
43 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:453
Count of miRNA genes:240
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000055982
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)106697895567750281Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106631944767750281Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
1579917Bp282Blood pressure QTL 2820.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106740031668164786Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106631944767750281Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)106631944767750281Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106631944768164786Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106631944768164786Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106631944768164786Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106631944768164786Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106631944767750281Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106592723382565079Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106134527681714865Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106134541382564856Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106750210873579767Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106124830367785171Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106631944767750281Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat

Markers in Region
D10Chm170  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21067,720,219 - 67,720,443 (+)MAPPERmRatBN7.2
Rnor_6.01070,137,131 - 70,137,354NCBIRnor6.0
Rnor_5.01069,767,838 - 69,768,061UniSTSRnor5.0
RGSC_v3.41071,002,650 - 71,002,873UniSTSRGSC3.4
Celera1066,664,547 - 66,664,770UniSTS
Cytogenetic Map10q26UniSTS
BE109015  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21067,728,917 - 67,729,074 (+)MAPPERmRatBN7.2
Rnor_6.01070,145,829 - 70,145,985NCBIRnor6.0
Rnor_5.01069,776,536 - 69,776,692UniSTSRnor5.0
RGSC_v3.41071,011,348 - 71,011,504UniSTSRGSC3.4
Celera1066,673,245 - 66,673,401UniSTS
Cytogenetic Map10q26UniSTS
RH134877  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21067,716,622 - 67,716,808 (+)MAPPERmRatBN7.2
Rnor_6.01070,133,534 - 70,133,719NCBIRnor6.0
Rnor_5.01069,764,241 - 69,764,426UniSTSRnor5.0
RGSC_v3.41070,999,053 - 70,999,238UniSTSRGSC3.4
Celera1066,660,950 - 66,661,135UniSTS
Cytogenetic Map10q26UniSTS
RH141104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21067,739,005 - 67,739,212 (+)MAPPERmRatBN7.2
Rnor_6.01070,155,916 - 70,156,122NCBIRnor6.0
Rnor_5.01069,786,623 - 69,786,829UniSTSRnor5.0
RGSC_v3.41071,021,435 - 71,021,641UniSTSRGSC3.4
Celera1066,683,332 - 66,683,538UniSTS
Cytogenetic Map10q26UniSTS
MARC_3929-3930:996679185:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21067,733,525 - 67,734,591 (+)MAPPERmRatBN7.2
Rnor_6.01070,150,436 - 70,151,501NCBIRnor6.0
Rnor_5.01069,781,143 - 69,782,208UniSTSRnor5.0
RGSC_v3.41071,015,955 - 71,017,020UniSTSRGSC3.4
Celera1066,677,852 - 66,678,917UniSTS
Cytogenetic Map10q26UniSTS
Lig3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21067,727,114 - 67,727,979 (+)MAPPERmRatBN7.2
Rnor_6.01070,144,026 - 70,144,890NCBIRnor6.0
Rnor_5.01069,774,733 - 69,775,597UniSTSRnor5.0
RGSC_v3.41071,009,545 - 71,010,409UniSTSRGSC3.4
Celera1066,671,442 - 66,672,306UniSTS
Cytogenetic Map10q26UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 51 35 19 35 5 5 74 35 41 11 5
Low 14 6 6 6 3 6 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001394035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_172067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000055982   ⟹   ENSRNOP00000052836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1067,717,857 - 67,738,968 (+)Ensembl
Rnor_6.0 Ensembl1070,134,768 - 70,155,881 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076703   ⟹   ENSRNOP00000068142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1070,153,427 - 70,154,512 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076739   ⟹   ENSRNOP00000068489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1067,717,812 - 67,741,142 (+)Ensembl
Rnor_6.0 Ensembl1070,134,729 - 70,158,055 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084076   ⟹   ENSRNOP00000069379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1067,717,812 - 67,798,414 (+)Ensembl
Rnor_6.0 Ensembl1070,136,855 - 70,156,772 (+)Ensembl
RefSeq Acc Id: NM_001394035   ⟹   NP_001380964
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,371 - 68,238,703 (+)NCBI
mRatBN7.21067,717,808 - 67,741,141 (+)NCBI
RefSeq Acc Id: NM_001394036   ⟹   NP_001380965
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,371 - 68,238,703 (+)NCBI
mRatBN7.21067,717,808 - 67,741,141 (+)NCBI
RefSeq Acc Id: NR_172067
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,371 - 68,238,703 (+)NCBI
mRatBN7.21067,717,808 - 67,741,141 (+)NCBI
RefSeq Acc Id: XM_008768020   ⟹   XP_008766242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,595 - 68,238,705 (+)NCBI
mRatBN7.21067,719,943 - 67,741,141 (+)NCBI
Rnor_6.01070,134,922 - 70,158,051 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768021   ⟹   XP_008766243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,602 - 68,238,705 (+)NCBI
mRatBN7.21067,719,943 - 67,741,141 (+)NCBI
Rnor_6.01070,134,925 - 70,158,051 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086028   ⟹   XP_038941956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,217,248 - 68,238,705 (+)NCBI
mRatBN7.21067,719,677 - 67,741,141 (+)NCBI
RefSeq Acc Id: XM_039086029   ⟹   XP_038941957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,885 - 68,238,705 (+)NCBI
mRatBN7.21067,718,320 - 67,741,141 (+)NCBI
RefSeq Acc Id: XM_039086030   ⟹   XP_038941958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,886 - 68,238,705 (+)NCBI
mRatBN7.21067,718,537 - 67,741,141 (+)NCBI
RefSeq Acc Id: XM_039086031   ⟹   XP_038941959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,593 - 68,230,798 (+)NCBI
mRatBN7.21067,719,943 - 67,733,236 (+)NCBI
RefSeq Acc Id: XM_063269079   ⟹   XP_063125149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,604 - 68,238,705 (+)NCBI
RefSeq Acc Id: XM_063269080   ⟹   XP_063125150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,216,888 - 68,238,705 (+)NCBI
RefSeq Acc Id: XM_063269081   ⟹   XP_063125151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,601 - 68,235,180 (+)NCBI
RefSeq Acc Id: XM_063269082   ⟹   XP_063125152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,217,510 - 68,238,705 (+)NCBI
RefSeq Acc Id: XM_063269083   ⟹   XP_063125153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81068,215,600 - 68,235,180 (+)NCBI
RefSeq Acc Id: XP_008766243   ⟸   XM_008768021
- Peptide Label: isoform X4
- UniProtKB: A0A096MKE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766242   ⟸   XM_008768020
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000052836   ⟸   ENSRNOT00000055982
RefSeq Acc Id: ENSRNOP00000069379   ⟸   ENSRNOT00000084076
RefSeq Acc Id: ENSRNOP00000068489   ⟸   ENSRNOT00000076739
RefSeq Acc Id: ENSRNOP00000068142   ⟸   ENSRNOT00000076703
RefSeq Acc Id: XP_038941957   ⟸   XM_039086029
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941958   ⟸   XM_039086030
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941956   ⟸   XM_039086028
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941959   ⟸   XM_039086031
- Peptide Label: isoform X8
RefSeq Acc Id: NP_001380965   ⟸   NM_001394036
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380964   ⟸   NM_001394035
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125153   ⟸   XM_063269083
- Peptide Label: isoform X7
- UniProtKB: Q5U2M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125151   ⟸   XM_063269081
- Peptide Label: isoform X5
- UniProtKB: Q5U2M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125149   ⟸   XM_063269079
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125150   ⟸   XM_063269080
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JV76 (UniProtKB/TrEMBL),   A6HHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125152   ⟸   XM_063269082
- Peptide Label: isoform X6
- UniProtKB: Q5U2M4 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MKE9-F1-model_v2 AlphaFold A0A096MKE9 1-1002 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697515
Promoter ID:EPDNEW_R8039
Type:initiation region
Name:Lig3_1
Description:DNA ligase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01070,134,766 - 70,134,826EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309875 AgrOrtholog
BioCyc Gene G2FUF-23919 BioCyc
Ensembl Genes ENSRNOG00000021815 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000055982.5 UniProtKB/TrEMBL
  ENSRNOT00000076739.3 UniProtKB/TrEMBL
  ENSRNOT00000084076.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3260.10 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
  3.30.1490.70 UniProtKB/TrEMBL
  3.30.1740.10 UniProtKB/TrEMBL
  3.40.50.10190 UniProtKB/TrEMBL
  DNA ligase/mRNA capping enzyme UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135421 IMAGE-MGC_LOAD
InterPro BRCT_dom UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/TrEMBL
  DNA_ligase UniProtKB/TrEMBL
  DNA_ligase_A_C UniProtKB/TrEMBL
  DNA_ligase_A_M UniProtKB/TrEMBL
  DNA_ligase_A_N UniProtKB/TrEMBL
  DNA_ligase_CS UniProtKB/TrEMBL
  DNA_ligase_N_sf UniProtKB/TrEMBL
  LIG3_BRCT UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Znf_PARP UniProtKB/TrEMBL
  Znf_PARP_sf UniProtKB/TrEMBL
KEGG Report rno:303369 UniProtKB/TrEMBL
MGC_CLONE MGC:95328 IMAGE-MGC_LOAD
NCBI Gene 303369 ENTREZGENE
PANTHER DNA LIGASE 1/3 FAMILY MEMBER UniProtKB/TrEMBL
  DNA LIGASE 3 UniProtKB/TrEMBL
Pfam DNA_ligase_A_C UniProtKB/TrEMBL
  DNA_ligase_A_M UniProtKB/TrEMBL
  DNA_ligase_A_N UniProtKB/TrEMBL
  LIG3_BRCT UniProtKB/TrEMBL
  zf-PARP UniProtKB/TrEMBL
PhenoGen Lig3 PhenoGen
PROSITE BRCT UniProtKB/TrEMBL
  DNA_LIGASE_A1 UniProtKB/TrEMBL
  DNA_LIGASE_A2 UniProtKB/TrEMBL
  DNA_LIGASE_A3 UniProtKB/TrEMBL
  PARP_ZN_FINGER_1 UniProtKB/TrEMBL
  PARP_ZN_FINGER_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021815 RatGTEx
SMART BRCT UniProtKB/TrEMBL
  zf-PARP UniProtKB/TrEMBL
Superfamily-SCOP DNA ligase/mRNA capping enzyme, catalytic domain UniProtKB/TrEMBL
  Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  Nucleic_acid_OB UniProtKB/TrEMBL
  SSF117018 UniProtKB/TrEMBL
  SSF52113 UniProtKB/TrEMBL
UniProt A0A096MKE9 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JV76 ENTREZGENE, UniProtKB/TrEMBL
  A6HHE1 ENTREZGENE, UniProtKB/TrEMBL
  F7FP17_RAT UniProtKB/TrEMBL
  Q5U2M4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Lig3  DNA ligase 3  Lig3  ligase III, DNA, ATP-dependent  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Lig3  ligase III, DNA, ATP-dependent  Lig3_predicted  ligase III, DNA, ATP-dependent (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Lig3_predicted  ligase III, DNA, ATP-dependent (predicted)      Symbol and Name status set to approved 70820 APPROVED