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Gene: Lig3 (DNA ligase 3) Rattus norvegicus
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Symbol: Lig3
Name: DNA ligase 3
Description: Exhibits DNA ligase activity. Involved in base-excision repair, DNA ligation. Localizes to the nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human LIG3 (DNA ligase 3); PARTICIPATES IN nucleotide excision repair pathway; base excision repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-hydroperoxycyclophosphamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA ligase (ATP) 3; ligase III, DNA, ATP-dependent; LOC303369
Orthologs:
Homo sapiens (human) : LIG3 (DNA ligase 3)  HGNC  Alliance
Mus musculus (house mouse) : Lig3 (ligase III, DNA, ATP-dependent)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lig3 (DNA ligase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LIG3 (DNA ligase 3)
Canis lupus familiaris (dog) : LIG3 (DNA ligase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lig3 (DNA ligase 3)
Sus scrofa (pig) : LIG3 (DNA ligase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01070,134,734 - 70,158,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01069,765,441 - 69,788,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,000,287 - 71,021,398 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,013,909 - 71,035,020 (+)NCBI
Celera1066,662,184 - 66,683,295 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lig3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309875
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.