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Gene: Ubtf (upstream binding transcription factor) Rattus norvegicus
Symbol: Ubtf
Name: upstream binding transcription factor
RGD ID: 3927
Description: Predicted to have several functions, including RNA polymerase I general transcription initiation factor activity; RNA polymerase I transcription regulatory region sequence-specific DNA binding activity; and scaffold protein binding activity. Predicted to be involved in cellular response to leukemia inhibitory factor; regulation of transcription, DNA-templated; and transcription by RNA polymerase I. Localizes to fibrillar center. Orthologous to human UBTF (upstream binding transcription factor); PARTICIPATES IN cisplatin drug pathway; RNA polymerase I transcription pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC679205; nucleolar transcription factor 1; similar to Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1); Tcfubf; Transcription factor UBF; UBF-1; upstream binding transcription factor, RNA polymerase I; upstream-binding factor 1
Homo sapiens (human) : UBTF (upstream binding transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Ubtf (upstream binding transcription factor, RNA polymerase I)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ubtf (upstream binding transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : UBTF (upstream binding transcription factor)
Canis lupus familiaris (dog) : UBTF (upstream binding transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ubtf (upstream binding transcription factor)
Sus scrofa (pig) : UBTF (upstream binding transcription factor)
Chlorocebus sabaeus (African green monkey) : UBTF (upstream binding transcription factor)
Heterocephalus glaber (naked mole-rat) : Ubtf (upstream binding transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01090,250,275 - 90,265,772 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1090,250,275 - 90,265,017 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01090,036,613 - 90,051,685 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,385,368 - 91,398,458 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11091,400,434 - 91,410,657 (-)NCBI
Celera1085,973,415 - 86,009,030 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ubtf
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3927
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.