Gene: Abcc3 (ATP binding cassette subfamily C member 3) Rattus norvegicus
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Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Description: ENCODES a protein that exhibits ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN canalicular bile acid transport; drug transmembrane transport; drug transport; PARTICIPATES IN doxorubicin pharmacokinetics pathway; etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; ASSOCIATED WITH bilirubin metabolic disorder; cholestasis; Dubin-Johnson syndrome; FOUND IN basolateral plasma membrane; integral component of plasma membrane (ortholog); INTERACTS WITH (S)-colchicine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; MLP-2; Mlp2; MRP-like protein 2; Mrp3; multidrug resistance protein 3; multidrug resistance-associated protein 3; organic anion transporter
Orthologs:
Homo sapiens (human) : ABCC3 (ATP binding cassette subfamily C member 3)  HGNC  Alliance
Mus musculus (house mouse) : Abcc3 (ATP-binding cassette, sub-family C (CFTR/MRP), member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc3 (ATP binding cassette subfamily C member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC3 (ATP binding cassette subfamily C member 3)
Canis lupus familiaris (dog) : ABCC3 (ATP binding cassette subfamily C member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc3 (ATP binding cassette subfamily C member 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01082,047,308 - 82,116,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01081,879,487 - 81,880,151 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01081,896,621 - 81,938,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41082,986,552 - 83,030,799 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1078,085,499 - 78,131,465 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71101
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2018-07-10
Status: ACTIVE