Ccl5 (C-C motif chemokine ligand 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ccl5 (C-C motif chemokine ligand 5) Rattus norvegicus
Analyze
Symbol: Ccl5
Name: C-C motif chemokine ligand 5
RGD ID: 69069
Description: Exhibits chemokine activity and heparin binding activity. Involved in several processes, including cellular response to organonitrogen compound; lymphocyte migration; and positive regulation of response to external stimulus. Localizes to extracellular space. Used to study Chagas disease; bronchiolitis obliterans; kidney disease; non-alcoholic fatty liver disease; and orchitis. Biomarker of several diseases, including alcoholic hepatitis; artery disease (multiple); cardiac arrest; lung disease (multiple); and uveitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including hepatitis B; hepatitis C; liver disease (multiple); pulmonary tuberculosis; and severe acute respiratory syndrome. Orthologous to human CCL5 (C-C motif chemokine ligand 5); PARTICIPATES IN syndecan signaling pathway; Chagas disease pathway; chemokine mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-C motif chemokine 5; chemokine (C-C motif) ligand 5; RANTES; regulated upon activation normal T-cell expressed and secreted; Scya5; SIS-delta; small inducible cytokine A5; small inducible cytokine A5 (RANTES); small-inducible cytokine A5; T-cell-specific protein RANTES
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21068,322,826 - 68,327,365 (-)NCBI
Rnor_6.0 Ensembl1070,739,800 - 70,744,315 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01070,739,764 - 70,744,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01070,373,353 - 70,377,892 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,605,791 - 71,610,330 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,620,206 - 71,624,712 (-)NCBI
Celera1067,264,203 - 67,268,742 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute Liver Failure  (ISO)
alcoholic hepatitis  (IEP,ISO)
allergic conjunctivitis  (IEP)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
Animal Toxoplasmosis  (IEP)
anti-basement membrane glomerulonephritis  (IEP)
arteriosclerosis  (IEP,ISO)
asthma  (IEP,ISO)
atopic dermatitis  (ISO)
autoimmune hepatitis  (ISO)
Breast Neoplasms  (ISO)
bronchiolitis obliterans  (IEP,IMP)
bronchopneumonia  (ISO)
cardiac arrest  (IEP)
Chagas disease  (IMP)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
chronic inflammatory demyelinating polyradiculoneuropathy  (ISO)
chronic obstructive pulmonary disease  (ISO)
COVID-19  (ISO)
Cytomegalovirus Infections  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
end stage renal disease  (IEP)
endometriosis  (IEP)
Endotoxemia  (IEP)
exercise-induced bronchoconstriction  (ISO)
Experimental Arthritis  (IEP,IMP)
Experimental Autoimmune Encephalomyelitis  (IEP,ISO)
Experimental Liver Cirrhosis  (ISO)
extrinsic allergic alveolitis  (ISO)
fatty liver disease  (ISO)
Fever  (IDA)
genital herpes  (ISO)
glomerulonephritis  (ISO)
glucose intolerance  (ISO)
hepatitis B  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
Hermansky-Pudlak syndrome  (ISO)
Herpesviridae Infections  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (IDA,IEP)
Hyperoxaluria  (IEP,ISO)
hypertension  (ISO)
Hypoventilation  (ISO)
Immediate Hypersensitivity  (IEP)
Inflammation  (IEP,ISO)
interstitial lung disease  (ISO)
invasive ductal carcinoma  (ISO)
kidney disease  (IMP)
liver cirrhosis  (ISO)
Liver Metastasis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (IEP)
malignant mesothelioma  (ISO)
Metabolic Syndrome  (IEP)
multiple sclerosis  (ISO)
Mycoplasma pneumoniae pneumonia  (ISO)
myocardial infarction  (IEP)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
non-alcoholic fatty liver  (ISO)
non-alcoholic fatty liver disease  (IEP,IMP)
non-alcoholic steatohepatitis  (ISO)
obesity  (IEP)
obstructive sleep apnea  (ISO)
orchitis  (IDA)
Ovarian Neoplasms  (ISO)
Pain  (IMP)
pancreatic cancer  (ISO)
pancreatitis  (IEP,ISO)
Paramyxoviridae Infections  (ISO)
peptic esophagitis  (IEP)
pleurisy  (ISO)
Pneumococcal Pneumonia  (ISO)
posterior uveitis  (IEP)
pre-eclampsia  (IEP)
primary biliary cholangitis  (ISO)
Pseudomonas Infections  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
Reperfusion Injury  (IEP,ISO)
Respiration Disorders  (ISO)
respiratory syncytial virus infectious disease  (ISO)
sciatic neuropathy  (IEP)
scrapie  (ISO)
Seasonal Allergic Rhinitis  (ISO)
Sepsis  (IEP)
severe acute respiratory syndrome  (ISO)
Spinal Cord Injuries  (ISO)
Spontaneous Abortions  (ISO)
Tissue Adhesions  (IMP)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
uveitis  (IEP)
Viral Bronchiolitis  (ISO)
visual epilepsy  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
(R)-noradrenaline  (ISO)
(S)-nicotine  (ISO)
1,4-benzoquinone  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropyrene  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-naphthylamine  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-nitroquinoline N-oxide  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7-ketocholesterol  (ISO)
8-Br-cAMP  (ISO)
8-chloro-2'-deoxyguanosine  (ISO)
9,10-anthraquinone  (ISO)
9-hydroxycanthin-6-one  (ISO)
acetamide  (EXP)
acrolein  (ISO)
albuterol  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (ISO)
alexidine  (ISO)
all-trans-retinoic acid  (ISO)
aluminium hydroxide  (ISO)
ammonium chloride  (EXP)
amorolfine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
apocynin  (ISO)
arecoline  (ISO)
aripiprazole  (ISO)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
atropine  (ISO)
beclomethasone  (ISO)
benazepril  (EXP)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzene-1,2,4-triol  (ISO)
benzethonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
beryllium sulfate  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-Funaltrexamine  (ISO)
beta-naphthoflavone  (ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
budesonide  (ISO)
butanal  (ISO)
butenafine  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
Calcimycin  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
carrageenan  (EXP,ISO)
catechol  (ISO)
celecoxib  (ISO)
cephaeline  (ISO)
cerium trichloride  (ISO)
chenodeoxycholic acid  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
chloroquine  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
ciglitazone  (ISO)
cisplatin  (EXP,ISO)
clopidogrel  (ISO)
cobalt atom  (ISO)
codeine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (ISO)
cytidine  (ISO)
D-glucose  (ISO)
D-penicillamine  (EXP)
dantrolene  (EXP)
decabromodiphenyl ether  (ISO)
Deguelin  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dequalinium  (ISO)
desipramine  (ISO)
dexamethasone  (EXP,ISO)
dichlorine  (ISO)
dichloromethane  (EXP)
diethylstilbestrol  (ISO)
diflorasone  (ISO)
digitoxigenin  (ISO)
digoxin  (ISO)
dimethyl sulfoxide  (ISO)
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium  (ISO)
dinitrogen  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
emetine  (ISO)
endosulfan  (ISO)
enilconazole  (ISO)
Erionite  (ISO)
ethambutol  (EXP)
ethanol  (ISO)
ethionamide  (EXP)
ethyl acetate  (ISO)
Ethyl icosapentate  (ISO)
ethylbenzene  (EXP)
ethylene glycol  (EXP)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
fenofibrate  (ISO)
Fexofenadine hydrochloride  (ISO)
flavonoids  (EXP)
flunisolide  (ISO)
fluoxetine  (ISO)
flutamide  (EXP)
fluticasone  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
formoterol fumarate  (ISO)
fragrance  (ISO)
fucoidan  (ISO)
fulvestrant  (ISO)
fumonisin B1  (ISO)
gemfibrozil  (EXP)
gentamycin  (EXP)
glucose  (ISO)
glutathione  (ISO)
glycine betaine  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
graphene oxide  (ISO)
GW 1929  (ISO)
helenalin  (ISO)
heparan sulfate  (ISO)
hesperetin  (ISO)
homocysteine  (ISO)
hyaluronic acid  (ISO)
hydrazines  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxytyrosol  (ISO)
indometacin  (EXP)
ionomycin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isotretinoin  (EXP,ISO)
itraconazole  (ISO)
kaempferol  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
lanatoside C  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lead(II) chloride  (ISO)
leukotriene B4  (EXP)
lipopolysaccharide  (EXP,ISO)
losartan  (EXP)
Luliconazole  (ISO)
LY294002  (ISO)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
maraviroc  (ISO)
masoprocol  (EXP)
mechlorethamine  (EXP)
meclocycline  (ISO)
melatonin  (ISO)
menadione  (EXP)
mercaptopurine  (EXP)
mercury dichloride  (EXP)
metam  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methionine sulfoximine  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
minocycline  (ISO)
monocrotaline  (EXP)
monodansylcadaverine  (ISO)
morphine  (ISO)
mycophenolic acid  (EXP)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
naloxone  (ISO)
naringin  (ISO)
neocuproine  (ISO)
neoechinulin A  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nicotine  (ISO)
nitric oxide  (ISO)
nitrogen dioxide  (ISO)
o-anisidine  (ISO)
oxaliplatin  (EXP)
oxytetracycline  (ISO)
ozone  (ISO)
palmatine  (ISO)
paracetamol  (EXP,ISO)
parthenolide  (ISO)
PCB138  (EXP)
PD123319  (EXP)
pentanal  (ISO)
Pentoxifylline  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
permethrin  (EXP)
pevonedistat  (ISO)
phenethyl caffeate  (EXP)
phenobarbital  (EXP)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phytoestrogen  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
platycodin D  (ISO)
poly(I:C)  (ISO)
polymyxin B2  (ISO)
prazosin  (ISO)
procyanidin B3  (ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
propidium  (ISO)
Proscillaridin  (ISO)
prostaglandin E2  (ISO)
purine-6-thiol  (EXP)
pyocyanine  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (EXP)
quercetin 3-O-beta-D-glucopyranoside  (EXP)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rifampicin  (EXP)
rofecoxib  (ISO)
rutin  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
S-nitrosoglutathione  (ISO)
salubrinal  (ISO)
SB 203580  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (ISO)
sodium chloride  (EXP)
sodium cholate  (ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
streptozocin  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tacrine  (EXP)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
taurocholic acid  (ISO)
telmisartan  (ISO)
terbinafine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tofacitinib  (ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
topotecan  (EXP)
trametinib  (ISO)
tremolite asbestos  (ISO)
triamcinolone acetonide  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
troglitazone  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
vanadyl sulfate  (ISO)
verteporfin  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
wortmannin  (ISO)
WR-1065  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of phospholipase D activity  (ISO)
aging  (IEP)
calcium ion transport  (ISO)
cell chemotaxis  (IEA)
cell-cell signaling  (ISO)
cellular calcium ion homeostasis  (ISO)
cellular response to alkyl hydroperoxide  (IEP)
cellular response to amino acid stimulus  (IEP)
cellular response to cytokine stimulus  (IEP)
cellular response to ethanol  (IEP)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to high density lipoprotein particle stimulus  (IEP)
cellular response to interferon-gamma  (IBA,ISO)
cellular response to interleukin-1  (IBA,ISO)
cellular response to lipid  (IEP)
cellular response to lipopolysaccharide  (IEP)
cellular response to morphine  (IEP)
cellular response to organic cyclic compound  (ISO)
cellular response to transforming growth factor beta stimulus  (IEP)
cellular response to tumor necrosis factor  (IBA,IEP,ISO)
cellular response to virus  (ISO)
cellular response to vitamin K  (IEP)
chemokine-mediated signaling pathway  (IBA,ISO,ISS)
chronic inflammatory response  (IEP)
dibenzo-p-dioxin metabolic process  (IEP)
eosinophil chemotaxis  (ISO)
exocytosis  (ISO)
G protein-coupled receptor signaling pathway  (IBA,ISO,ISS)
immune response  (IEA)
inflammatory response  (IBA,IEA,IEP,ISO)
leukocyte cell-cell adhesion  (ISO)
lipopolysaccharide-mediated signaling pathway  (ISO)
lymphocyte chemotaxis  (IBA,IDA)
MAPK cascade  (ISO)
monocyte chemotaxis  (IBA)
negative regulation by host of viral transcription  (ISO)
negative regulation of cell death  (IMP)
negative regulation of chemokine-mediated signaling pathway  (IEA)
negative regulation of G protein-coupled receptor signaling pathway  (ISO)
negative regulation of macrophage apoptotic process  (IEA,ISO)
negative regulation of neuron death  (IMP)
negative regulation of T cell apoptotic process  (ISO)
negative regulation of viral genome replication  (ISO)
neutrophil activation  (ISO)
neutrophil chemotaxis  (IBA)
positive chemotaxis  (IEA)
positive regulation of angiogenesis  (IMP)
positive regulation of calcium ion transport  (ISO)
positive regulation of cell adhesion  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell-cell adhesion mediated by integrin  (ISO)
positive regulation of cellular biosynthetic process  (ISO)
positive regulation of epithelial cell proliferation  (IEA,ISO)
positive regulation of ERK1 and ERK2 cascade  (IBA)
positive regulation of fever generation  (IDA)
positive regulation of gene expression  (IDA,IMP)
positive regulation of GTPase activity  (IBA)
positive regulation of homotypic cell-cell adhesion  (ISO)
positive regulation of macrophage chemotaxis  (ISO)
positive regulation of mast cell chemotaxis  (IDA)
positive regulation of monocyte chemotaxis  (IEA,ISO)
positive regulation of natural killer cell chemotaxis  (ISO)
positive regulation of neuron differentiation  (IMP)
positive regulation of osteoclast differentiation  (IDA)
positive regulation of phosphatidylinositol 3-kinase signaling  (IDA,ISO)
positive regulation of phosphorylation  (ISO)
positive regulation of protein tyrosine kinase activity  (IEA)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of T cell apoptotic process  (ISO)
positive regulation of T cell chemotaxis  (IBA,IDA,ISO)
positive regulation of T cell migration  (ISO)
positive regulation of T cell proliferation  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
protein kinase B signaling  (ISO)
protein phosphorylation  (IEA)
pseudopodium assembly  (IDA)
regulation of insulin secretion  (ISO,ISS)
regulation of neuron death  (ISO,ISS)
regulation of T cell activation  (ISO)
response to activity  (IEP)
response to alcohol  (IEP)
response to bacterium  (IEP)
response to cholesterol  (IEP)
response to cytokine  (IEP,ISO)
response to drug  (IEP)
response to estrogen  (IEP)
response to glucocorticoid  (IEP)
response to insulin  (IEP)
response to interferon-gamma  (IDA)
response to lipopolysaccharide  (IEP)
response to nutrient levels  (IEP)
response to organic cyclic compound  (IEP)
response to salt stress  (IEP)
response to toxic substance  (ISO)
response to tumor necrosis factor  (IEA,ISO)
response to virus  (IEP)
signal transduction  (IEA)
T-helper 1 cell diapedesis  (IDA)

Cellular Component
cytoplasm  (IEA,ISO)
extracellular space  (IBA,IDA,IEA,ISO)

References

References - curated
1. Akyildiz H, etal., Surgery. 2008 Sep;144(3):404-9. Epub 2008 Jul 10.
2. Al-Qahtani A, etal., Genet Mol Res. 2012 Apr 10;11(2):855-62. doi: 10.4238/2012.April.10.1.
3. Avdoshina V, etal., Glia. 2010 Oct;58(13):1630-9.
4. Barbe MF, etal., J Orthop Res. 2008 Oct;26(10):1320-6.
5. Barnes DA, etal., J Clin Invest. 1998 Jun 15;101(12):2910-9.
6. Baumer W, etal., Br J Dermatol. 2004 Oct;151(4):823-30.
7. Bautista AP, Life Sci. 2001 Mar 16;68(17):1939-49. doi: 10.1016/s0024-3205(01)00986-9.
8. Benamar K, etal., Eur J Pharmacol. 2008 Sep 11;592(1-3):93-5. Epub 2008 Jul 11.
9. Berres ML, etal., J Clin Invest. 2010 Nov;120(11):4129-40. doi: 10.1172/JCI41732. Epub 2010 Oct 18.
10. Bhangoo S, etal., Mol Pain. 2007 Dec 12;3:38.
11. Bhushan S, etal., J Immunol. 2008 Apr 15;180(8):5537-47.
12. Bless NM, etal., J Immunol 2000 Mar 1;164(5):2650-9.
13. Bogdanski P, etal., Int J Clin Pharmacol Ther. 2007 Oct;45(10):563-7.
14. Bonaros N, etal., J Thorac Cardiovasc Surg. 2008 Oct;136(4):1044-53. Epub 2008 Jul 7.
15. Bondar' IA, etal., Ter Arkh. 2008;80(1):52-6.
16. Borel JC, etal., PLoS One. 2009 Aug 24;4(8):e6733.
17. Boven LA, etal., Clin Exp Immunol. 2000 Nov;122(2):257-63.
18. Brattstrom A, etal., Phytomedicine. 2010 Jul;17(8-9):551-6. Epub 2010 Jan 22.
19. Brzezinska-Blaszczyk E, etal., J Interferon Cytokine Res. 2007 Nov;27(11):911-9.
20. Camelo S, etal., J Ocul Pharmacol Ther. 2009 Feb;25(1):9-21.
21. Carrigan SO, etal., J Immunol. 2010 Sep 15;185(6):3602-9. Epub 2010 Aug 18.
22. Castellani ML, etal., Calcif Tissue Int. 2007 Jan;80(1):60-7. Epub 2006 Dec 8.
23. Cavalher-Machado SC, etal., Int Immunopharmacol. 2008 Nov;8(11):1552-60. Epub 2008 Jul 29.
24. Chang YS, etal., Int J Mol Sci. 2020 Apr 30;21(9). pii: ijms21093179. doi: 10.3390/ijms21093179.
25. Charni F, etal., Cancer Epidemiol Biomarkers Prev. 2011 Jul;20(7):1439-46. doi: 10.1158/1055-9965.EPI-11-0341. Epub 2011 May 24.
26. Chen CJ, etal., J Gen Virol. 2010 Apr;91(Pt 4):1028-37. Epub 2009 Dec 9.
27. Chen J, etal., J Virol. 2010 Feb;84(3):1289-301. Epub 2009 Nov 11.
28. Chen Y, etal., Gut. 2004 Dec;53(12):1772-80.
29. Chung J, etal., Biotechnol Lett. 2008 Sep;30(9):1553-8. Epub 2008 May 14.
30. Colombo G, etal., Shock. 2007 Mar;27(3):326-33.
31. Defaux A, etal., Brain Res. 2010 Sep 24;1353:213-24. Epub 2010 Jul 16.
32. Di Stefano A, etal., Thorax. 2009 Nov;64(11):968-75. Epub 2009 Aug 23.
33. Dodd J, etal., J Immunol. 2009 Jan 15;182(2):1174-81.
34. dos Santos AC, etal., J Neuroimmunol. 2005 May;162(1-2):122-9.
35. Doupis J, etal., J Clin Endocrinol Metab. 2009 Mar 10.
36. Duell EJ, etal., Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):726-31.
37. Duo J and Stenken JA, Anal Bioanal Chem. 2010 Oct 30.
38. El Feghaly RE, etal., Pediatr Infect Dis J. 2010 Apr;29(4):e26-31.
39. El Seweidy MM, etal., J Pharm Pharmacol. 2005 Nov;57(11):1467-74.
40. Farivar AS, etal., Exp Mol Pathol. 2003 Dec;75(3):210-6.
41. Garcia GE, etal., FASEB J. 2008 Feb;22(2):445-54. Epub 2007 Sep 26.
42. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
43. Glass WG, etal., J Immunol. 2004 Sep 15;173(6):4030-9. doi: 10.4049/jimmunol.173.6.4030.
44. Goodwill AG, etal., Microcirculation. 2009 Nov;16(8):667-84.
45. Grau V, etal., Transplant Proc 1999 May;31(3):1571.
46. Harandi AM, etal., J Virol. 2003 Jan;77(2):953-62.
47. Hassan AO, etal., Cell. 2020 Jun 10. pii: S0092-8674(20)30742-X. doi: 10.1016/j.cell.2020.06.011.
48. Herder C, etal., Diabetes. 2005 Dec;54 Suppl 2:S11-7.
49. Hofstetter C, etal., Crit Care Med. 2005 Oct;33(10):2317-22.
50. Hohsfield LA and Humpel C, Curr Neurovasc Res. 2010 Aug 1;7(3):192-200.
51. Hoshino Y, etal., J Immunol. 2004 May 15;172(10):6251-8.
52. Hou Y, etal., Acta Pharm Sin B. 2016 May;6(3):212-21. doi: 10.1016/j.apsb.2016.03.002. Epub 2016 Mar 22.
53. Huang WC, etal., J Neuroinflammation. 2010 Apr 29;7:28.
54. Huik K, etal., PLoS One. 2016 Jun 15;11(6):e0156850. doi: 10.1371/journal.pone.0156850. eCollection 2016.
55. Huo X, etal., Exp Ther Med. 2019 Jul;18(1):172-178. doi: 10.3892/etm.2019.7572. Epub 2019 May 10.
56. Im GJ, etal., Acta Otolaryngol. 2005 Apr;125(4):370-7.
57. Jeschke MG, etal., Mol Med. 2002 Aug;8(8):443-50.
58. Johnsen-Soriano S, etal., Ocul Immunol Inflamm. 2010 Jun;18(3):208-15.
59. Jungraithmayr W, etal., Eur Respir J. 2010 Jun;35(6):1354-63. Epub 2009 Oct 19.
60. Kawai T, etal., J Immunol. 1999 Sep 15;163(6):3269-78.
61. Kim HJ, etal., J Immunol. 2008 Dec 15;181(12):8753-60.
62. Kim HK, etal., Biotechnol Lett. 2006 Jan;28(1):17-23.
63. Kimoff RJ, etal., Eur Respir J. 2010 Sep 16.
64. Kizu T, etal., Am J Physiol Gastrointest Liver Physiol. 2015 Apr 1;308(7):G613-24. doi: 10.1152/ajpgi.00289.2014. Epub 2015 Jan 23.
65. Knight BC, etal., J Neuroimmunol. 2005 Mar;160(1-2):41-7. Epub 2004 Dec 19.
66. Kotzampassi K, etal., Mol Nutr Food Res. 2009 Jun;53(6):770-9.
67. Lau YL and Peiris JS, Hong Kong Med J. 2009 Feb;15 Suppl 2:43-6.
68. Le Goffic R, etal., Endocrinology 2002 Apr;143(4):1434-40.
69. Lee CM, etal., Sci Rep. 2017 Jun 16;7(1):3698. doi: 10.1038/s41598-017-03956-7.
70. Leifeld L, etal., J Pathol. 2003 Mar;199(3):335-44. doi: 10.1002/path.1298.
71. Lewis DK, etal., J Neuroimmunol. 2010 Jun;223(1-2):31-8.
72. Li BH, etal., Transl Res. 2017 Feb;180:103-117.e4. doi: 10.1016/j.trsl.2016.08.006. Epub 2016 Aug 31.
73. Li S, etal., JCI Insight. 2020 May 19. pii: 138070. doi: 10.1172/jci.insight.138070.
74. Lines JL, etal., J Immunol. 2010 Sep 1;185(5):2980-8. Epub 2010 Jul 23.
75. Louboutin JP, etal., FASEB J. 2010 Oct 12.
76. Maier R, etal., Mol Vis. 2008 Mar 27;14:637-43.
77. Manczak M, etal., J Autoimmun. 2002 Jun;18(4):259-70.
78. Meleth AD, etal., Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4295-301.
79. MGD data from the GO Consortium
80. Mohs A, etal., J Hepatol. 2017 Apr;66(4):743-753. doi: 10.1016/j.jhep.2016.12.011. Epub 2016 Dec 21.
81. Mu W, etal., J Am Soc Nephrol. 2005 Dec;16(12):3651-60. Epub 2005 Oct 26.
82. Mukaino M, etal., Exp Neurol. 2010 Aug;224(2):403-14. Epub 2010 May 16.
83. Nakajima K, etal., Diabetes Care. 2003 Mar;26(3):892-8.
84. Naura AS, etal., Lab Invest. 2009 Nov;89(11):1243-51. Epub 2009 Sep 14.
85. NCBI rat LocusLink and RefSeq merged data July 26, 2002
86. Nellen A, etal., PLoS One. 2012;7(5):e36614. doi: 10.1371/journal.pone.0036614. Epub 2012 May 4.
87. Nesbeth YC, etal., J Immunol. 2010 May 15;184(10):5654-62. Epub 2010 Apr 16.
88. Ng PC, etal., Arch Dis Child. 2005 Apr;90(4):422-3. doi: 10.1136/adc.2004.053660.
89. Nguyen Y, etal., Virology. 2008 Oct 25;380(2):182-90. Epub 2008 Sep 2.
90. Nischalke HD, etal., Mediators Inflamm. 2004 Dec;13(5-6):357-9. doi: 10.1080/09629350400003159.
91. Nomura S, etal., Thromb Res. 2005;115(4):277-85.
92. Oh SB, etal., J Neurosci. 2001 Jul 15;21(14):5027-35.
93. Oh-i K, etal., Br J Ophthalmol. 2007 Feb;91(2):237-42. Epub 2006 Sep 20.
94. Online Mendelian Inheritance in Man, OMIM (TM).
95. Oshima M, etal., Lung. 1999;177(4):229-40.
96. Ozaki A, etal., Graefes Arch Clin Exp Ophthalmol. 2003 May;241(5):394-402. Epub 2003 Apr 4.
97. Palaniappan R, etal., J Immunol. 2006 Feb 15;176(4):2346-56.
98. Pan HC, etal., Neurochem Res. 2009 Jul;34(7):1304-16. Epub 2009 Jan 17.
99. Park MH, etal., Exp Cell Res. 2009 Oct 1;315(16):2715-26. Epub 2009 Jun 24.
100. Pipeline to import KEGG annotations from KEGG into RGD
101. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
102. Promrat K, etal., Gastroenterology. 2003 Feb;124(2):352-60. doi: 10.1053/gast.2003.50061.
103. Rebourcet D, etal., Int J Androl. 2010 Apr;33(2):413-24. Epub 2009 Jan 3.
104. Reverter JL, etal., Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1378-82. Epub 2008 Oct 31.
105. RGD automated data pipeline
106. RGD automated import pipeline for gene-chemical interactions
107. Roffe E, etal., Microbes Infect. 2010 Aug;12(8-9):669-76. Epub 2010 May 7.
108. Roson MI, etal., J Cell Physiol. 2010 Jul;224(1):41-8.
109. Rouhani FN, etal., Am J Respir Crit Care Med. 2009 Dec 1;180(11):1114-21. Epub 2009 Sep 3.
110. Ruddell RG, etal., Hepatology. 2009 Jan;49(1):227-39.
111. Russo RC, etal., Am J Respir Cell Mol Biol. 2010 Sep 10.
112. Samuel I, etal., J Gastrointest Surg. 2006 Jul-Aug;10(7):950-9.
113. Sanchez A, etal., Neuropeptides. 2009 Aug;43(4):315-20. Epub 2009 Jun 3.
114. Sanchez-Castanon M, etal., Int J Tuberc Lung Dis. 2009 Apr;13(4):480-5.
115. Schafer A, etal., Br J Pharmacol. 2008 Jul;154(5):1047-54. Epub 2008 May 12.
116. Schaier M, etal., Am J Physiol Renal Physiol. 2009 Sep;297(3):F769-80. Epub 2009 Jun 17.
117. Scheven BA, etal., Biochem Biophys Res Commun. 1999 Jan 27;254(3):773-8.
118. Segawa S, etal., Clin Exp Immunol. 2010 Jun;160(3):394-402. Epub 2010 Jan 19.
119. Sekine Y, etal., Am J Respir Cell Mol Biol. 2000 Dec;23(6):719-26.
120. Serag AR, etal., Eur J Cardiothorac Surg. 2010 Apr;37(4):853-8. Epub 2009 Nov 20.
121. Sharma AK, etal., Respir Res. 2009 Jun 26;10:58.
122. Sharma GR, etal., Adv Exp Med Biol. 2008;614:83-91.
123. Soria G, etal., Cytokine. 2008 Oct;44(1):191-200. Epub 2008 Sep 13.
124. Stevens KE, etal., Immunol Cell Biol. 2019 Mar;97(3):317-325. doi: 10.1111/imcb.12221. Epub 2019 Jan 24.
125. Stormes KA, etal., Breast Cancer Res Treat. 2005 Jan;89(2):209-12. doi: 10.1007/s10549-004-5328-3.
126. Stowell NC, etal., Respir Res. 2009 Jun 1;10:43.
127. Suga M, etal., Am J Respir Crit Care Med. 2000 Nov;162(5):1940-8.
128. Sugawa T, etal., Gut. 2008 May;57(5):575-81. Epub 2008 Jan 25.
129. Tagliabue C, etal., J Infect Dis. 2008 Oct 15;198(8):1180-8.
130. Tan MC, etal., J Immunol. 2009 Feb 1;182(3):1746-55.
131. Tang M, etal., J Cereb Blood Flow Metab. 2010 Jan;30(1):119-29. Epub 2009 Sep 16.
132. Tang NL, etal., Clin Chem. 2005 Dec;51(12):2333-40. doi: 10.1373/clinchem.2005.054460. Epub 2005 Sep 29.
133. Tavares E and Minano FJ, Fundam Clin Pharmacol. 2004 Apr;18(2):163-9.
134. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
135. Thio CL, etal., J Immunol. 2008 Dec 1;181(11):7944-7. doi: 10.4049/jimmunol.181.11.7944.
136. Thorne PS, etal., Am J Respir Crit Care Med. 2006 Apr 1;173(7):759-68. Epub 2005 Dec 30.
137. Tian M, etal., Eur J Pediatr. 2009 Aug;168(8):963-7. Epub 2008 Nov 13.
138. Tinsley JH, etal., Am J Hypertens. 2009 Oct;22(10):1107-14. Epub 2009 Jul 16.
139. Toblli JE, etal., Urol Res. 2005 Nov;33(5):358-67. Epub 2005 Nov 13.
140. Tribouillard-Tanvier D, etal., J Virol. 2012 Oct;86(19):10377-83. doi: 10.1128/JVI.01340-12. Epub 2012 Jul 11.
141. Trinh L, etal., Mol Vis. 2008;14:2428-34. Epub 2008 Dec 19.
142. Tripathy D and Grammas P, J Neuroinflammation. 2009 Mar 16;6:10.
143. Tripathy D, etal., Neurobiol Aging. 2010 Jan;31(1):8-16. Epub 2008 Apr 28.
144. Tsai HT, etal., Med Oncol. 2012 Dec;29(4):2771-9. doi: 10.1007/s12032-012-0189-9. Epub 2012 Feb 29.
145. Tyner JW, etal., Nat Med. 2005 Nov;11(11):1180-7. Epub 2005 Oct 2.
146. Uller L, etal., Respir Res. 2010 May 9;11(1):54.
147. Umezawa M, etal., Cytokine. 2008 Aug;43(2):105-9. Epub 2008 Jul 1.
148. Veillard NR, etal., Circ Res. 2004 Feb 6;94(2):253-61. Epub 2003 Dec 1.
149. Vera PL, etal., Exp Biol Med (Maywood). 2008 May;233(5):620-6. Epub 2008 Mar 28.
150. Wang CH, etal., Respir Res. 2005 May 11;6:42. doi: 10.1186/1465-9921-6-42.
151. Wang Y, etal., Br J Pharmacol. 2009 Jul;157(6):1004-13. Epub 2009 Jun 5.
152. Wang Y, etal., Int Immunopharmacol. 2006 Dec 5;6(12):1825-32. Epub 2006 Aug 31.
153. Ward SE, etal., Antivir Ther. 2005;10(2):263-75.
154. Wasmuth HE, etal., Hepatology. 2004 Aug;40(2):327-34. doi: 10.1002/hep.20322.
155. Wei XQ, etal., Zhonghua Gan Zang Bing Za Zhi. 2007 Aug;15(8):585-8.
156. Weigt SS, etal., Am J Transplant. 2008 Jul;8(7):1512-22.
157. Wen X, etal., J Biol Chem. 2010 Sep 24;285(39):29981-8. Epub 2010 Jul 27.
158. Wender-Ozegowska E, etal., Acta Obstet Gynecol Scand. 2008;87(1):14-9.
159. Westerweel PE, etal., Thromb Haemost. 2008 Apr;99(4):794-5.
160. Wu FY, etal., Mol Cancer Res. 2008 Aug;6(8):1276-88.
161. Wu H, etal., Kidney Int. 2005 Jun;67(6):2178-86.
162. Xie JY, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Mar;28(3):238-41.
163. Xie M, etal., Chin Med J (Engl). 2008 Jan 5;121(1):73-7.
164. Yao Y, etal., J Hum Genet. 2018 Jul;63(7):831-839. doi: 10.1038/s10038-018-0452-9. Epub 2018 Apr 27.
165. Yeligar SM, etal., J Immunol. 2009 Nov 1;183(9):5964-76. Epub 2009 Oct 14.
166. Zeng Y, etal., Biol Pharm Bull. 2007 Aug;30(8):1438-44.
167. Zhang C, etal., Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Dec;33(12):1279-82.
168. Zhang M, etal., Diabetes Metab Res Rev. 2010 Sep;26(6):455-63.
169. Zhang YG, etal., Arch Med Res. 2010 Jan;41(1):50-8.
170. Zhao DY, etal., Zhonghua Er Ke Za Zhi. 2008 Feb;46(2):89-93.
171. Zhernakova A, etal., Genes Immun. 2006 Oct;7(7):544-9. Epub 2006 Jul 20.
172. Zietkowski Z, etal., Respiration. 2010;80(6):463-71. Epub 2009 Dec 7.
173. Zou LP and Zhang SL, Zhongguo Dang Dai Er Ke Za Zhi. 2010 Mar;12(3):181-3.
Additional References at PubMed
PMID:1375672   PMID:1699135   PMID:7517217   PMID:7544376   PMID:7545673   PMID:8558019   PMID:8631850   PMID:8699119   PMID:9139699   PMID:9407497   PMID:9417081   PMID:9469451  
PMID:10488085   PMID:10490959   PMID:10660125   PMID:10734056   PMID:10841574   PMID:10910894   PMID:12477932   PMID:12899200   PMID:15001559   PMID:15504940   PMID:15530372   PMID:15557190  
PMID:15718270   PMID:16778803   PMID:16830364   PMID:17001303   PMID:17218081   PMID:18337562   PMID:18832695   PMID:19779041   PMID:20132097   PMID:21147091   PMID:21148126   PMID:21167894  
PMID:21297082   PMID:21827949   PMID:22292067   PMID:22450806   PMID:22752444   PMID:22960654   PMID:23460747   PMID:23480650   PMID:23498802   PMID:23620790   PMID:23696660   PMID:23979485  
PMID:24656930   PMID:25635831   PMID:28381538   PMID:31032369  


Genomics

Candidate Gene Status
Ccl5 is a candidate Gene for QTL Eau3
Ccl5 is a candidate Gene for QTL Bp299
Ccl5 is a candidate Gene for QTL Eau9
Comparative Map Data
Ccl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21068,322,826 - 68,327,365 (-)NCBI
Rnor_6.0 Ensembl1070,739,800 - 70,744,315 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01070,739,764 - 70,744,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01070,373,353 - 70,377,892 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,605,791 - 71,610,330 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,620,206 - 71,624,712 (-)NCBI
Celera1067,264,203 - 67,268,742 (-)NCBICelera
Cytogenetic Map10q26NCBI
CCL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1735,871,491 - 35,880,793 (-)EnsemblGRCh38hg38GRCh38
GRCh381735,871,491 - 35,880,360 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371734,198,495 - 34,207,364 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361731,222,608 - 31,231,490 (-)NCBINCBI36hg18NCBI36
Celera1731,108,052 - 31,116,934 (-)NCBI
Cytogenetic Map17q12NCBI
HuRef1730,383,508 - 30,392,390 (-)NCBIHuRef
CHM1_11734,263,060 - 34,271,942 (-)NCBICHM1_1
Ccl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,416,604 - 83,421,344 (-)NCBIGRCm39mm39
GRCm39 Ensembl1183,416,604 - 83,421,344 (-)Ensembl
GRCm381183,525,778 - 83,530,518 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,525,778 - 83,530,518 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,339,280 - 83,344,020 (-)NCBIGRCm37mm9NCBIm37
MGSCv361183,341,974 - 83,346,692 (-)NCBImm8
Celera1193,127,305 - 93,132,049 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.66NCBI
Ccl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495548110,293,399 - 10,301,143 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495548110,293,758 - 10,301,118 (-)NCBIChiLan1.0ChiLan1.0
CCL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11721,210,798 - 21,219,172 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,210,798 - 21,219,172 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01720,915,198 - 20,923,530 (+)NCBIMhudiblu_PPA_v0panPan3
CCL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,817,409 - 37,823,852 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl937,817,305 - 37,823,852 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha937,039,892 - 37,046,335 (+)NCBI
ROS_Cfam_1.0938,627,353 - 38,633,796 (+)NCBI
UMICH_Zoey_3.1937,410,157 - 37,416,605 (+)NCBI
UNSW_CanFamBas_1.0937,695,725 - 37,702,162 (+)NCBI
UU_Cfam_GSD_1.0937,783,127 - 37,789,578 (+)NCBI
Ccl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560236,815,103 - 36,821,857 (+)NCBI
SpeTri2.0NW_004936490253,279 - 259,947 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,648,598 - 39,659,118 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,652,731 - 39,659,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,218,074 - 41,228,604 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCL5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11629,351,214 - 29,361,317 (-)NCBI
Ccl5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248753,334,136 - 3,342,085 (-)NCBI

Position Markers
D10Chm184  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21068,328,123 - 68,328,363 (+)MAPPER
Rnor_6.01070,745,062 - 70,745,301NCBIRnor6.0
Rnor_5.01070,378,651 - 70,378,890UniSTSRnor5.0
RGSC_v3.41071,611,089 - 71,611,328UniSTSRGSC3.4
Celera1067,269,501 - 67,269,740UniSTS
Cytogenetic Map10q26UniSTS
RH129414  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21068,322,907 - 68,323,098 (+)MAPPER
Rnor_6.01070,739,846 - 70,740,036NCBIRnor6.0
Rnor_5.01070,373,435 - 70,373,625UniSTSRnor5.0
RGSC_v3.41071,605,873 - 71,606,063UniSTSRGSC3.4
Celera1067,264,285 - 67,264,475UniSTS
Cytogenetic Map10q26UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101482789492423564Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)1020170031102897474Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102152390683549467Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)12152390690312401Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102152390690312401Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102290149793886300Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)1027237530101482600Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1027237530102427718Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102878928073789280Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103098380575983805Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103191939778343192Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103317903078179030Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103334319278343192Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103513942480139424Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103618592982675365Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103618592995845311Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)104051404485514044Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)104051404485514044Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1041260363106105607Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104318865981042642Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1043289657108540162Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104370495588704955Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104659302198939209Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104684834691848346Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104684834691848346Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104684834691848346Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105063833795638337Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)105128920384596393Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)105128920384596393Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)105128920384596393Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105310471898104718Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1053621375112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1053621375112626471Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105362581598939209Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105363748594807701Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)1055224855100224855Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1055678976112626471Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)1055679084102427604Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1056698730101698730Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1060450007105450007Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1060875260105875260Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1060875260105875260Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1060875260105875260Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1062096293107096293Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106464817584601269Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)1064648175101691360Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1064648175102149713Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1064648175102149713Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106464831185513822Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1065590122110590122Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1065992275110992275Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1065992275110992275Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1067880046112626471Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1067988218110992091Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106830503785514044Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1069123603101482600Rat
631565Hcuc4Hepatic copper content QTL 44.15hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106934845975983662Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1069385595112626471Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1069385595112626471Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106991083276109716Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1070166960112626471Rat
1642290Bp299Blood pressure QTL 299arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)107064708971727943Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000014865
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 9 11 6 14 6 1 7 10
Low 2 18 32 21 5 21 6 7 24 28 23 1 6
Below cutoff 4 8 8 8 2 4 27 7 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014865   ⟹   ENSRNOP00000014865
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1070,739,800 - 70,744,315 (-)Ensembl
RefSeq Acc Id: NM_031116   ⟹   NP_112378
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21068,322,826 - 68,327,365 (-)NCBI
Rnor_6.01070,739,764 - 70,744,303 (-)NCBI
Rnor_5.01070,373,353 - 70,377,892 (-)NCBI
RGSC_v3.41071,605,791 - 71,610,330 (-)RGD
Celera1067,264,203 - 67,268,742 (-)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_112378   ⟸   NM_031116
- Peptide Label: precursor
- UniProtKB: Q6PED1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014865   ⟸   ENSRNOT00000014865
Protein Domains
SCY

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697533
Promoter ID:EPDNEW_R8058
Type:single initiation site
Name:Ccl5_1
Description:C-C motif chemokine ligand 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01070,744,318 - 70,744,378EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69069 AgrOrtholog
Ensembl Genes ENSRNOG00000010906 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014865 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014865 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921268 IMAGE-MGC_LOAD
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81780 UniProtKB/TrEMBL
MGC_CLONE MGC:72786 IMAGE-MGC_LOAD
NCBI Gene 81780 ENTREZGENE
PANTHER PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccl5 PhenoGen
PROSITE SMALL_CYTOKINES_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218419
UniProt CCL5_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6PED1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-08 Ccl5  C-C motif chemokine ligand 5  Ccl5  chemokine (C-C motif) ligand 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Ccl5  chemokine (C-C motif) ligand 5  Scya5  small inducible cytokine A5  Symbol and Name updated 629477 APPROVED
2002-06-10 Scya5  small inducible cytokine A5      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression increases during renal allografts 61510
gene_expression increases during renal allografts 68880
gene_expression mRNA expression in testicular somatic cells increases in response to Sendai virus infection 704384