Enables several functions, including amyloid-beta binding activity; nerve growth factor binding activity; and neurotrophin TRKA receptor binding activity. Involved in several processes, including positive regulation of cell communication; regulation of apoptotic process; and regulation of neuron projection development. Located in several cellular components, including dendrite membrane; neuronal cell body membrane; and perikaryon. Is active in neuromuscular junction and presynaptic membrane. Used to study degenerative disc disease; glaucoma; hypertension; and middle cerebral artery infarction. Biomarker of several diseases, including brain disease (multiple); neuropathy (multiple); polycystic ovary syndrome; portal hypertension; and respiratory syncytial virus infectious disease. Human ortholog(s) of this gene implicated in Alzheimer's disease and depressive disorder. Orthologous to human NGFR (nerve growth factor receptor); PARTICIPATES IN cytokine mediated signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 17alpha-ethynylestradiol.
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NGFR mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NGFR mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NGFR mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NGFR mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NGFR mRNA
pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA] and pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NGFR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA
Cisplatin promotes the reaction [jinfukang results in increased expression of NGFR mRNA] and jinfukang promotes the reaction [Cisplatin results in increased expression of NGFR mRNA]
[Cyclosporine co-treated with NGF protein] results in increased expression of NGFR mRNA and NGFR protein affects the reaction [[Cyclosporine co-treated with NGF protein] results in increased activity of CASP9 protein]
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NGFR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA
[[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of NGFR-AS1 mRNA] which results in increased expression of NGFR mRNA and [[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of NGFR-AS1 mRNA] which results in increased expression of NGFR mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Flurbiprofen results in increased expression of NGFR mRNA] more ...
[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of NGFR gene more ...
[[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of NGFR-AS1 mRNA] which results in increased expression of NGFR mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of NGFR mRNA
Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA] and Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]
N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [Acetaminophen results in increased expression of NGFR mRNA]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGFR protein] and Naproxen inhibits the reaction [Capsaicin results in increased expression of NGFR protein]
[[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of NGFR-AS1 mRNA] which results in increased expression of NGFR mRNA more ...
[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NGFR mRNA
N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [Acetaminophen results in increased expression of NGFR mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA] and pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]
SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA] and SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGFR protein] and Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGFR protein]
[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NGFR mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NGFR mRNA
[NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NGFR mRNA
Epicatechin blocks pro-nerve growth factor (proNGF)-mediated retinal neurodegeneration via inhibition of p75 neurotrophin receptor expression in a rat model of diabetes .
Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism.
Localization of brain-derived neurotrophic factor, neurotrophin-4, tropomyosin-related kinase b receptor, and p75 NTR receptor by high-resolution immunohistochemistry on the adult mouse neuromuscular junction.
Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR.
Role of low-affinity nerve growth factor receptor inhibitory antibody in reducing pain behavior and calcitonin gene-related Peptide expression in a rat model of wrist joint inflammatory pain.
Deficient p75 low-affinity neurotrophin receptor expression does alter the composition of cellular infiltrate in experimental autoimmune encephalomyelitis in C57BL/6 mice.
The effect of Anti-NGF receptor (p75 Neurotrophin Receptor) antibodies on nociceptive behavior and activation of spinal microglia in the rat brachial plexus avulsion model.
Mutation of low affinity nerve growth factor receptor gene is associated with the hypertensive phenotype in spontaneously hypertensive inbred rat strains.
Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells.
Differential up-regulation of neurotrophin receptors and functional activity of neurotrophins on peripheral blood eosinophils of patients with allergic rhinitis, atopic dermatitis and nonatopic subjects.
induced in dying neurons following seizure, ischemia, excitotoxic agents, axotomy, and in cortical neurons following experimental allergic encephalomyelitis
