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AMIGO3 is an NgR1/p75 co-receptor signalling axon growth inhibition in the acute phase of adult central nervous system injury. |
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Epicatechin blocks pro-nerve growth factor (proNGF)-mediated retinal neurodegeneration via inhibition of p75 neurotrophin receptor expression in a rat model of diabetes . |
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3. |
Compromise of cortical proNGF maturation causes selective retrograde atrophy in cholinergic nucleus basalis neurons. |
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Regulation of neuronal type genes in congestive heart failure rats. |
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Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism. |
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ProNGF Induces p75-Mediated Death of Oligodendrocytes following Spinal Cord Injury. |
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Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord. |
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The role of C-terminal binding protein 2 in Schwann cell differentiation after sciatic nerve crush. |
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NGF, BDNF, leptin, and mast cells in human coronary atherosclerosis and metabolic syndrome. |
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Nerve growth factor levels and mast cell distribution in human coronary atherosclerosis. |
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13. |
Divergent roles of p75NTR and Trk receptors in BDNF's effects on dendritic spine density and morphology. |
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Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease. |
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Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor. |
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16. |
The neurotrophin receptor p75NTR as a positive modulator of myelination. |
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SNPs in neurotrophin system genes and Alzheimer's disease in an Italian population. |
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Expression of nerve growth factor receptors is correlated with progression and prognosis of human pancreatic cancer. |
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mRNA for NGF and p75 in the central nervous system of rats affected by experimental allergic encephalomyelitis. |
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A novel p75NTR signaling pathway promotes survival, not death, of immunopurified neocortical subplate neurons. |
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Neurotrophins Redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport. |
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Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt-sensitive rat. |
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Ethanol reduces expression of the nerve growth factor receptor, but not nerve growth factor protein levels in the neonatal rat cerebellum. |
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Increased nerve growth factor and its receptors in atopic dermatitis: an immunohistochemical study. |
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Decreased density of forebrain cholinergic neurons in experimental autoimmune dementia. |
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Transplanting p75-suppressed bone marrow stromal cells promotes functional behavior in a rat model of spinal cord injury. |
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p75NTR suppression in rat bone marrow stromal stem cells significantly reduced their rate of apoptosis during neural differentiation. |
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Blockage of the afferent sensitive pathway prevents sympathetic atrophy and hemodynamic alterations in rat portal hypertension. |
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Inhibition of pan neurotrophin receptor p75 attenuates diesel particulate-induced enhancement of allergic airway responses in C57/B16J mice. |
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Molecular and structural insight into proNGF engagement of p75NTR and sortilin. |
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31. |
Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction. |
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32. |
Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin binding. |
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PLAIDD, a type II death domain protein that interacts with p75 neurotrophin receptor. |
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Localization of brain-derived neurotrophic factor, neurotrophin-4, tropomyosin-related kinase b receptor, and p75 NTR receptor by high-resolution immunohistochemistry on the adult mouse neuromuscular junction. |
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37. |
Rat ISS GO annotations from GOA human gene data--August 2006 |
GOA data from the GO Consortium
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Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. |
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Selective in vivo fluorescence labelling of cholinergic neurons containing p75(NTR) in the rat basal forebrain. |
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Structure of nerve growth factor complexed with the shared neurotrophin receptor p75. |
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Decreased cutaneous expression of stem cell factor and of the p75NGF receptor in urticaria. |
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Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR. |
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Role of low-affinity nerve growth factor receptor inhibitory antibody in reducing pain behavior and calcitonin gene-related Peptide expression in a rat model of wrist joint inflammatory pain. |
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Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma. |
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p75NTR expression in rat urinary bladder sensory neurons and spinal cord with cyclophosphamide-induced cystitis. |
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Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. |
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Nerve growth factor receptor staining of suction biopsies in the diagnosis of Hirschsprung's disease. |
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A missense polymorphism (S205L) of the low-affinity neurotrophin receptor p75NTR gene is associated with depressive disorder and attempted suicide. |
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Deficient p75 low-affinity neurotrophin receptor expression does alter the composition of cellular infiltrate in experimental autoimmune encephalomyelitis in C57BL/6 mice. |
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Activation of the mitogen-activated protein kinase pathway through p75NTR: a common mechanism for the neurotrophin family. |
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Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. |
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Recombinant human nerve growth factor (rhNGF-beta) gene transfer promotes regeneration of crush-injured mental nerve in rats. |
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Light and electron microscopic immunohistochemical observations of p75 nerve growth factor receptor-immunoreactive dermal nerves in prurigo nodularis. |
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Increased levels of truncated nerve growth factor receptor in urine of mildly demented patients with Alzheimer's disease. |
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Neurotrophins regulate cholinergic synaptic transmission in cultured rat sympathetic neurons through a p75-dependent mechanism. |
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Ovarian expression of alpha (1)- and beta (2)-adrenoceptors and p75 neurotrophin receptors in rats with steroid-induced polycystic ovaries. |
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The effect of Anti-NGF receptor (p75 Neurotrophin Receptor) antibodies on nociceptive behavior and activation of spinal microglia in the rat brachial plexus avulsion model. |
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Rat ISS GO annotations from MGI mouse gene data--August 2006 |
MGD data from the GO Consortium
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p75NTR-dependent modulation of cellular handling of reactive oxygen species. |
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Ethanol exposure alters neurotrophin receptor expression in the rat central nervous system: Effects of prenatal exposure. |
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BDNF is expressed in skeletal muscle satellite cells and inhibits myogenic differentiation. |
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Nerve growth factor receptor expressing human basal forebrain neurons: pathologic alterations in Alzheimer's and Parkinson's disease. |
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NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR. |
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Impaired glucose tolerance and insulinopenia in the GK-rat causes peripheral neuropathy. |
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Electronic Transfer of LocusLink and RefSeq Data |
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Mutation of low affinity nerve growth factor receptor gene is associated with the hypertensive phenotype in spontaneously hypertensive inbred rat strains. |
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Sortilin is essential for proNGF-induced neuronal cell death. |
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Iodine plus n-3 fatty acid supplementation augments rescue of postnatal neuronal abnormalities in iodine-deficient rat cerebellum. |
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Co-induction of p75NTR and p75NTR-associated death executor in neurons after zinc exposure in cortical culture or transient ischemia in the rat. |
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Cholinergic transmitter and neurotrophic activities in Lewy body dementia: similarity to Parkinson's and distinction from Alzheimer disease. |
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Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells. |
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Pipeline to import KEGG annotations from KEGG into RGD
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Structural characterization of the self-association of the death domain of p75(NTR.). |
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GOA pipeline |
RGD automated data pipeline
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Data Import for Chemical-Gene Interactions |
RGD automated import pipeline for gene-chemical interactions
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Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions. |
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p75 neurotrophin receptor participates in the choroidal antiangiogenic and apoptotic effects of T-lymphocyte-derived microparticles. |
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The p75 neurotrophin receptor interacts with multiple MAGE proteins. |
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Tentative Sequence Identification Numbers |
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
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Vascular and Neuronal Protection Induced by the Ocular Administration of Nerve Growth Factor in Diabetic-Induced Rat Encephalopathy. |
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Enhanced expression of NGF receptors in multiple sclerosis lesions. |
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Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle. |
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P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp. |
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Protective effects of octacosanol on 6-hydroxydopamine-induced Parkinsonism in rats via regulation of ProNGF and NGF signaling. |
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Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling. |
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Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease. |
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