Ccl2 (C-C motif chemokine ligand 2) - Rat Genome Database

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Gene: Ccl2 (C-C motif chemokine ligand 2) Rattus norvegicus
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Symbol: Ccl2
Name: C-C motif chemokine ligand 2
RGD ID: 3645
Description: Enables chemokine activity and heparin binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and leukocyte migration. Located in several cellular components, including perikaryon; perinuclear region of cytoplasm; and rough endoplasmic reticulum. Colocalizes with C-fiber. Used to study several diseases, including artery disease (multiple); diabetic angiopathy; interstitial lung disease (multiple); kidney disease (multiple); and obstructive jaundice. Biomarker of several diseases, including artery disease (multiple); cerebrovascular disease (multiple); lung disease (multiple); non-alcoholic fatty liver disease (multiple); and periodontitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and tuberculosis (multiple). Orthologous to human CCL2 (C-C motif chemokine ligand 2); PARTICIPATES IN angiotensin II signaling pathway; vascular endothelial growth factor signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (R,R,R)-alpha-tocopherol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-C motif chemokine 2; chemokine (C-C motif) ligand 2; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; MCP-1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic protein 1; Scya2; Sigje; small inducible cytokine A2; Small inducible gene JE; small-inducible cytokine A2
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21067,005,424 - 67,007,222 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1067,005,424 - 67,007,226 (+)Ensembl
Rnor_6.01069,412,065 - 69,413,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1069,412,017 - 69,413,870 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,047,091 - 69,048,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41070,256,263 - 70,258,061 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1065,952,968 - 65,954,766 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model