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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:36904
Term: elemental selenium
Definition: null
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2multiple interactionsISOCCL2 (Homo sapiens)6480464CTD[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of CCL2 mRNA; Selenium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Selenium inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL2 mRNA]PMID:16143069 PMID:21481475
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