GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | increases expression | EXP | | 6480464 | CTD | Cocaine results in increased expression of CCL2 protein | PMID:20354174 | Ccl2 | increases expression | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein | PMID:20354174 | Ccl2 | increases secretion | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Cocaine results in increased secretion of CCL2 protein | PMID:10065903 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein] | PMID:20354174 | | ||||||||||||||||||||||
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