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Gene: CCL2 (C-C motif chemokine ligand 2) Homo sapiens
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Symbol: CCL2
Name: C-C motif chemokine ligand 2
Description: Predicted to have CCR2 chemokine receptor binding activity and chemokine activity. Involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and regulation of apoptotic process. Localizes to extracellular region. Implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune hypersensitivity disease (multiple); gastrointestinal system cancer (multiple); tuberculosis (multiple); and vasculitis (multiple). Biomarker of several diseases, including cardiovascular system disease (multiple); lung disease (multiple); nephritis (multiple); non-alcoholic fatty liver disease (multiple); and retinal disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-C motif chemokine 2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; MGC9434; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; monocyte chemotactic protein 1; monocyte secretory protein JE; SCYA2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small-inducible cytokine A2; SMC-CF
Orthologs:
Mus musculus (house mouse) : Ccl2 (chemokine (C-C motif) ligand 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccl2 (C-C motif chemokine ligand 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CCL2 (C-C motif chemokine ligand 2)
Canis lupus familiaris (dog) : CCL2 (C-C motif chemokine ligand 2)
Sus scrofa (pig) : CCL2 (chemokine (C-C motif) ligand 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1734,255,218 - 34,257,203 (+)EnsemblGRCh38hg38GRCh38
GRCh381734,255,285 - 34,257,203 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371732,582,296 - 32,584,222 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361729,606,409 - 29,608,335 (+)NCBINCBI36hg18NCBI36
Build 341729,606,408 - 29,608,331NCBI
Celera1729,492,130 - 29,494,042 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1728,767,599 - 28,769,525 (+)NCBIHuRef
CHM1_11732,646,183 - 32,648,095 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model