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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731046
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2increases secretionEXP 6480464CTDThioacetamide results in increased secretion of CCL2 proteinPMID:27605418
CCL2increases expressionISOCcl2 (Mus musculus)6480464CTDThioacetamide results in increased expression of CCL2 mRNAPMID:36343683
CCL2increases expressionISOCcl2 (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of CCL2 mRNA; Thioacetamide results in increased expression of CCL2 proteinPMID:19389872 PMID:25051504 PMID:26957569 PMID:34492290
CCL2multiple interactionsISOCcl2 (Mus musculus)6480464CTDEdaravone inhibits the reaction [Thioacetamide results in increased expression of CCL2 mRNA]PMID:36343683
CCL2multiple interactionsISOCcl2 (Rattus norvegicus)6480464CTDIron, Dietary affects the reaction [Thioacetamide affects the expression of CCL2 mRNA]PMID:18032466
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